A Therapeutic Target for Smoking-Associated Lung Cancer
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Turner, N. C., Seckl, M. J.
(2010)
A Therapeutic Target for Smoking-Associated Lung Cancer.
Science Translational Medicine, 2 (62).
ISSN 1946-6234
Full text not available from this repository.
Abstract
A report in this issue of Science Translational Medicine reveals that amplification of the FGFR1 gene-which encodes fibroblast growth factor receptor 1-is a major oncogenic aberration in squamous cell lung cancer. This genetic variation may represent the first relatively high-frequency therapeutic target of smoking-associated lung cancer.
Item Type: | Article |
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All Authors: | Turner, N. C., Seckl, M. J. |
Additional Information: | ISI Document Delivery No.: 735UG Times Cited: 0 Cited Reference Count: 32 Turner, Nicholas C. Seckl, Michael J. Astra Zeneca N.C.T. is a consultant for Novartis and receives research funding from Astra Zeneca. Amer assoc advancement science Washington |
Uncontrolled Keywords: | fibroblast-growth-factor polymorphism array analysis monoclonal-antibody breast-cancer fgfr1 amplifications tumors inhibition carcinomas expression |
Research teams: | ICR divisions > Breast Cancer Research > Gene Function ICR divisions > Molecular Pathology > Gene Function |
Depositing User: | Barry Jenkins |
Date Deposited: | 05 Apr 2011 12:07 |
Last Modified: | 10 Aug 2011 13:59 |
URI: | http://publications.icr.ac.uk/id/eprint/10612 |
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