Lalondrelle, S., Sohaib, S. A., Castellano, I. A., Mears, D., Huddart, R., Khoo, V. (2012) Investigating the relationship between virtual cystoscopy image quality and CT slice thickness. BRITISH JOURNAL OF RADIOLOGY, 85 (1016). pp. 1112-1117. ISSN 0007-1285

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Abstract

Objective: To investigate the effect of reconstruction slice thickness on image quality at CT virtual cystoscopy (VC). Methods: Pelvic CT examinations in bladder cancer patients were reconstructed at different slice thicknesses (0.6-5 mm) and intervals, and resulting VC images assessed. Quality indicators were ridging, holes, floaters and dimpling artefacts, tumour definition, and an overall score, ranked 1 (best) to 7 (worst). CT number and standard deviation (SD) for bladder contents and bladder wall were recorded. The mean SD was used as a measure of noise, and the contrast-to-noise ratio (CNR) was calculated as the CT number difference between them divided by the average image noise. The mean CNR across the three levels was used for analysis. Each qualitative image quality measure was compared with CT number, noise and CNR measurements. Results: Dimpling artefacts increased with thinner slice reconstruction and correlated with increased noise, often resulting in poor tumour definition. The best overall image quality score was seen for VC images reconstructed at 1.2 mm slice thickness, probably because of the competing effects of spatial resolution and CNR. Conclusion: A slice thickness reconstruction <1.2 mm does not provide for better image quality at VC owing to the presence of increased noise.

Item Type:	Article
Authors (ICR Faculty only):	Khoo, Vincent and Huddart, Robert
All Authors:	Lalondrelle, S., Sohaib, S. A., Castellano, I. A., Mears, D., Huddart, R., Khoo, V.
Additional Information:	ISI Document Delivery No.: 988OK Times Cited: 0 Cited Reference Count: 26 Lalondrelle, S. Sohaib, S. A. Castellano, I. A. Mears, D. Huddart, R. Khoo, V. Institute of Cancer Research; Bob Champion Cancer Trust; Cancer Research UK Section of Radiotherapy (CRUK)[C46/A2131]; NHS; RMH/ICR general clinical research fund; NHS Executive This work was supported by the Institute of Cancer Research, the Bob Champion Cancer Trust and Cancer Research UK Section of Radiotherapy (CRUK) grant number C46/A2131. We acknowledge NHS funding to the NIHR Biomedical Research Centre. SL was funded by the RMH/ICR general clinical research fund.This work was undertaken in The Royal Marsden NHS Foundation Trust, which received a proportion of its funding from the NHS Executive; the views expressed in this publication are those of the authors and not necessarily those of the NHS Executive. British inst radiology London
Uncontrolled Keywords:	material-filled bladder multidetector row ct clinical-experience computed-tomography urinary-bladder colon phantom colonography tumors neoplasms complications
Research teams:	Clinical Units > Urology Unit ICR divisions > Radiotherapy and Imaging > Clinical Academic Radiotherapy (Huddart)
Depositing User:	Alexander Smithson
Date Deposited:	04 Oct 2012 16:12
Last Modified:	04 Oct 2012 16:12
URI:	http://publications.icr.ac.uk/id/eprint/11912

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