Lee, Y. K., McVey, G. P., South, C. P., Dearnaley, D. P. (2013) Coplanar intensity-modulated radiotherapy class solution for patients with prostate cancer with bilateral hip prostheses with and without nodal involvement. MEDICAL DOSIMETRY, 38 (2). pp. 165-170. ISSN 0958-3947

Full text not available from this repository.

Abstract

Dose distributions for prostate radiotherapy are difficult to predict in patients with bilateral hip prostheses in situ, due to image distortions and difficulty in dose calculation. The feasibility of delivering curative doses to prostate using intensity-modulated radiotherapy (IMRT) in patients with bilateral hip prostheses was evaluated. Planning target volumes for prostate only (PTV1) and pelvic nodes (PTV2) were generated from data on 5 patients. PTV1 and PTV2 dose prescriptions were 70 Gy and 60 Gy, respectively, in 35 fractions, and an additional nodal boost of 65 Gy was added for 1 plan. Rectum, bladder, and bowel were also delineated. Beam angles and segments were chosen to best avoid entering through the prostheses. Dose-volume data were assessed with respect to clinical objectives. The plans achieved the required prescription doses to the PTVs. Five-field IMRT plans were adequate for patients with relatively small prostheses (head volumes < 60 cm(3)) but 7-field plans were required for patients with larger prostheses. Bowel and bladder doses were clinically acceptable for all patients. Rectal doses were deemed clinically acceptable, although the V-50 Gy objective was not met for 4/5 patients. We describe an IMRT solution for patients with bilateral hip prostheses of varying size and shape, requiring either localized or whole pelvic radiotherapy for prostate cancer. (C) 2013 American Association of Medical Dosimetrists.

Item Type:	Article
Authors (ICR Faculty only):	Dearnaley, David
All Authors:	Lee, Y. K., McVey, G. P., South, C. P., Dearnaley, D. P.
Additional Information:	ISI Document Delivery No.: 142WR Times Cited: 0 Cited Reference Count: 17 Lee, Young K. McVey, Gerard P. South, Chris P. Dearnaley, David P. Elsevier science inc New york
Uncontrolled Keywords:	IMRT Prostate Bilateral hip prostheses trials nodes
Research teams:	ICR divisions > Radiotherapy and Imaging > Clinical Academic Radiotherapy (Dearnaley)
Depositing User:	Barry Jenkins
Date Deposited:	18 Jun 2013 11:21
Last Modified:	18 Jun 2013 11:21
URI:	http://publications.icr.ac.uk/id/eprint/12503

Actions (login required)

View Item