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Eosinophilic fasciitis associated with hypereosinophilia, abnormal bone-marrow karyotype and inversion of chromosome 5

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Ferguson, J. S., Bosworth, J., Min, T., Mercieca, J., Holden, C. A. (2014) Eosinophilic fasciitis associated with hypereosinophilia, abnormal bone-marrow karyotype and inversion of chromosome 5. CLINICAL AND EXPERIMENTAL DERMATOLOGY, 39 (2). pp. 150-153. ISSN 0307-6938

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Abstract

We report the case of a male patient presenting with eosinophilia, pulmonary oedema and eosinophilic fasciitis (EF). He had the classic clinical appearance and magnetic resonance imaging of EF. Cytogenetic analysis of the bone marrow revealed a previously undescribed pericentric inversion of chromosome 5. Overall, the presentation was consistent with a diagnosis of chronic eosinophilic leukaemia, not otherwise specified (CEL-NOS). Dermatologists should consult a haematologist in cases of EF, in order to rule out possible haematological malignancies.

Item Type: Article
All Authors: Ferguson, J. S., Bosworth, J., Min, T., Mercieca, J., Holden, C. A.
Additional Information: ISI Document Delivery No.: AA6BJ Times Cited: 0 Cited Reference Count: 10 Ferguson, J. S. Bosworth, J. Min, T. Mercieca, J. Holden, C. A. Wiley-blackwell Hoboken
Uncontrolled Keywords: cellulitis patient
Research teams: Clinical Units > Other Royal Marsden Services/Clinical Units
Depositing User: Alexander Smithson
Date Deposited: 20 Mar 2014 10:14
Last Modified: 20 Mar 2014 10:14
URI: http://publications.icr.ac.uk/id/eprint/13113

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