Attard, G., Antonarakis, E. S. (2016) AR aberrations and resistance to abiraterone or enzalutamide. NATURE REVIEWS UROLOGY, 13 (12). pp. 697-698. ISSN 1759-4812

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Abstract

Resistance to abiraterone or enzalutamide is a major medical burden the duration of benefit is highly variable and cross-resistance often occurs when these two agents are given sequentially. Blood-based analysis of androgen receptor splice variants and AR copy number gain or mutations could enhance understanding of the mechanisms of resistance and improve management of patients with castration-resistant prostate cancer.

Item Type:	Editorial
Authors (ICR Faculty only):	Attard, Gert
All Authors:	Attard, G., Antonarakis, E. S.
Additional Information:	ISI Document Delivery No.: EE9SL Times Cited: 0 Cited Reference Count: 10 Attard, Gerhardt Antonarakis, Emmanuel S. 0 NATURE PUBLISHING GROUP NEW YORK NAT REV UROL
Research teams:	ICR divisions > Molecular Pathology > Treatment Resistance
Depositing User:	Barry Jenkins
Date Deposited:	10 Jan 2017 09:31
Last Modified:	10 Jan 2017 09:31
URI:	http://publications.icr.ac.uk/id/eprint/15606

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