Wigneshweraraj, S., Bose, D., Burrows, P. C., Joly, N., Schumacher, J., Rappas, M., Pape, T., Zhang, X. D., Stockley, P., Severinov, K., Buck, M. (2008) Modus operandi of the bacterial RNA polymerase containing the sigma(54) promoter-specificity factor. MOLECULAR MICROBIOLOGY, 68 (3). pp. 538-546. ISSN 0950-382X

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Abstract

Bacterial sigma (sigma) factors confer gene specificity upon the RNA polymerase, the central enzyme that catalyses gene transcription. The binding of the alternative sigma factor sigma(54) confers upon the RNA polymerase special functional and regulatory properties, making it suited for control of several major adaptive responses. Here, we summarize our current understanding of the interactions the sigma(54) factor makes with the bacterial transcription machinery.

Item Type:	Article
All Authors:	Wigneshweraraj, S., Bose, D., Burrows, P. C., Joly, N., Schumacher, J., Rappas, M., Pape, T., Zhang, X. D., Stockley, P., Severinov, K., Buck, M.
Uncontrolled Keywords:	ENHANCER-BINDING PROTEINS; OPEN COMPLEX-FORMATION; ESCHERICHIA-COLI; TRANSCRIPTION INITIATION; DNA COMPLEX; CONFORMATIONAL-CHANGES; ANGSTROM RESOLUTION; STRUCTURAL BASIS; FACTOR SIGMA-54; FLAP DOMAIN
Research teams:	Closed research groups > Pearl Group
Depositing User:	Users 10 not found.
Date Deposited:	21 May 2008 09:26
Last Modified:	14 Sep 2011 13:36
URI:	http://publications.icr.ac.uk/id/eprint/6101

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