Article

Stojic, L., Lun, A. T. L., Mangeri, J., Mascalchi, P., Quarantotti, V., Barr, A. R., Bakal, C., Marioni, J. C., Gergely, F., Odom, D. T. (2018) Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis. NUCLEIC ACIDS RESEARCH, 46 (12). pp. 5950-5966. ISSN 0305-1048

Heldt, F. S., Barr, A. R., Cooper, S., Bakal, C., Novak, B. (2018) A comprehensive model for the proliferation-quiescence decision in response to endogenous DNA damage in human cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115 (10). pp. 2532-2537. ISSN 0027-8424

Sanchez-Alvarez, M., del Pozo, M. A., Bakal, C. (2017) AKT-mTOR signaling modulates the dynamics of IRE1 RNAse activity by regulating ER-mitochondria contacts. SCIENTIFIC REPORTS, 7. ISSN 2045-2322

Barr, A. R., Cooper, S., Heldt, F. S., Butera, F., Stoy, H., Mansfeld, J., Novak, B., Bakal, C. (2017) DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression. Nature Communications, 8. ISSN 2041-1723

Sailem, H. Z., Bakal, C. (2017) Identification of clinically predictive metagenes that encode components of a network coupling cell shape to transcription by image-omics. GENOME RESEARCH, 27 (2). pp. 196-207. ISSN 1088-9051

Sero, J. E., Bakal, C. (2017) Multiparametric Analysis of Cell Shape Demonstrates that beta-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion. Cell Systems, 4 (1). pp. 84-96. ISSN 2405-4712

Cooper, S., Barr, A. R., Glen, R., Bakal, C. (2017) NucliTrack: an integrated nuclei tracking application. BIOINFORMATICS, 33 (20). pp. 3320-3322. ISSN 1367-4803

Mardakheh, F. K., Sailem, H. Z., Kumper, S., Tape, C. J., McCully, R. R., Paul, A., Anjomani-Virmouni, S., Jorgensen, C., Poulogiannis, G., Marshall, C. J., Bakal, C. (2017) Proteomics profiling of interactome dynamics by colocalisation analysis (COLA). MOLECULAR BIOSYSTEMS, 13 (1). pp. 92-105. ISSN 1742-206X

Pascual-Vargas, P., Cooper, S., Sero, J., Bousgouni, V., Arias-Garcia, M., Bakal, C. (2017) RNAi screens for Rho GTPase regulators of cell shape and YAP/TAZ localisation in triple negative breast cancer. Scientific Data, 4. ISSN 2052-4463

Asghar, U. S., Barr, A. R., Cutts, R., Beaney, M., Babina, I., Sampath, D., Giltnane, J., Lacap, J. A., Crocker, L., Young, A., Pearson, A., Herrera-Abreu, M. T., Bakal, C., Turner, N. C. (2017) Single-Cell Dynamics Determines Response to CDK4/6 Inhibition in Triple-Negative Breast Cancer. CLINICAL CANCER RESEARCH, 23 (18). pp. 5561-5572. ISSN 1078-0432

Natrajan, R., Sailem, H., Mardakheh, F. K., Garcia, M. A., Tape, C. J., Dowsett, M., Bakal, C., Yuan, Y. Y. (2016) Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology-Genomic Integration Analysis. PLOS MEDICINE, 13 (2). ISSN 1549-1277

Cooper, S., Sadok, A., Bousgouni, V., Bakal, C. (2015) Apolar and polar transitions drive the conversion between amoeboid and mesenchymal shapes in melanoma cells. MOLECULAR BIOLOGY OF THE CELL, 26 (22). pp. 4163-4170. ISSN 1059-1524

Sanchez-Alvarez, M., Zhang, Q. F., Finger, F., Wakelam, M. J. O., Bakal, C. (2015) Cell cycle progression is an essential regulatory component of phospholipid metabolism and membrane homeostasis. Open Biology, 5 (9). ISSN 2046-2441

Sero, J. E., Sailem, H. Z., Ardy, R. C., Almuttaqi, H., Zhang, T. L., Bakal, C. (2015) Cell shape and the microenvironment regulate nuclear translocation of NF-kappa B in breast epithelial and tumor cells. Molecular Systems Biology, 11 (3). ISSN 1744-4292

Barr, A. R., Bakal, C. (2015) A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly. Scientific Reports, 5. ISSN 2045-2322

Sailem, H. Z., Sero, J. E., Bakal, C. (2015) Visualizing cellular imaging data using PhenoPlot. Nature Communications, 6. ISSN 2041-1723

Sailem, H., Bousgouni, V., Cooper, S., Bakal, C. (2014) Cross-talk between Rho and Rac GTPases drives deterministic exploration of cellular shape space and morphological heterogeneity. OPEN BIOLOGY, 4 (1). ISSN 1230-1612

Yin, Z., Sailem, H., Sero, J., Ardy, R., Wong, S. T. C., Bakal, C. (2014) How cells explore shape space: A quantitative statistical perspective of cellular morphogenesis. BIOESSAYS, 36 (12). pp. 1195-1203. ISSN 0265-9247

Evans, L., Sailem, H., Vargas, P. P., Bakal, C. (2013) Inferring signalling networks from images. JOURNAL OF MICROSCOPY-OXFORD, 252 (1). pp. 1-7. ISSN 0022-2720

Yin, Z., Sadok, A., Sailem, H., McCarthy, A., Xia, X. F., Li, F. H., Garcia, M. A., Evans, L., Barr, A. R., Perrimon, N., Marshall, C. J., Wong, S. T. C., Bakal, C. (2013) A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes. NATURE CELL BIOLOGY, 15 (7). pp. 860-871. ISSN 1465-7392

Garcia, M. A., Alvarez, M. S., Sailem, H., Bousgouni, V., Sero, J., Bakal, C. (2012) Differential RNAi screening provides insights into the rewiring of signalling networks during oxidative stress. MOLECULAR BIOSYSTEMS, 8 (10). pp. 2605-2613. ISSN 1742-206X

Bakal, C. (2011) Drosophila RNAi screening in a postgenomic world. BRIEFINGS IN FUNCTIONAL GENOMICS, 10 (4). pp. 197-205. ISSN 2041-2649

Sero, J. E., Thodeti, C. K., Mammoto, A., Bakal, C., Thomas, S., Ingber, D. E. (2011) Paxillin Mediates Sensing of Physical Cues and Regulates Directional Cell Motility by Controlling Lamellipodia Positioning. PLOS ONE, 6 (12). ISSN 1932-6203

Review Article

Spill, F., Bakal, C., Mak, M. (2018) Mechanical and Systems Biology of Cancer. COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 16. pp. 237-245. ISSN 2001-0370

Spill, F., Bakal, C., Mak, M. (2018) Mechanical and Systems Biology of Cancer. COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 16. pp. 237-245. ISSN 2001-0370

Cooper, S., Bakal, C. (2017) Accelerating Live Single-Cell Signalling Studies. TRENDS IN BIOTECHNOLOGY, 35 (5). pp. 422-433. ISSN 0167-7799

Sailem, H. Z., Cooper, S., Bakal, C. (2016) Visualizing quantitative microscopy data: History and challenges. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY, 51 (2). pp. 96-101. ISSN 1040-9238

Editorial

Barr, A. R., Bakal, C. (2012) A direct look at RNAi screens. Molecular Systems Biology, 8. ISSN 1744-4292

Bakal, C., Perrimon, N. (2010) Realizing the Promise of RNAi High Throughput Screening. DEVELOPMENTAL CELL, 18 (4). pp. 506-507. ISSN 1534-5807