Article

Wetterskog, D., Lopez-Garcia, M. A., Lambros, M. B., A'Hern, R., Geyer, F. C., Milanezi, F., Cabral, M. C., Natrajan, R., Gauthier, A., Shiu, K. K., Orr, N., Shousha, S., Gatalica, Z., Mackay, A., Palacios, J., Reis, J. S., Weigelt, B. (2012) Adenoid cystic carcinomas constitute a genomically distinct subgroup of triple-negative and basal-like breast cancers. JOURNAL OF PATHOLOGY, 226 (1). pp. 84-96. ISSN 0022-3417

Weigelt, B., Pusztai, L., Ashworth, A., Reis, J. S. (2012) Challenges translating breast cancer gene signatures into the clinic. NATURE REVIEWS CLINICAL ONCOLOGY, 9 (1). pp. 58-64. ISSN 1759-4774

Lacroix-Triki, M., Lambros, M. B., Geyer, F. C., Suarez, P. H., Reis, J. S., Weigelt, B. (2011) Absence of microsatellite instability in mucinous carcinomas of the breast. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 4 (1). 22-U38. ISSN 1936-2625

Geyer, F. C., Lacroix-Triki, M., Savage, K., Arnedos, M., Lambros, M. B., MacKay, A., Natrajan, R., Reis-Filho, J. S. (2011) beta-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation. MODERN PATHOLOGY, 24 (2). pp. 209-231. ISSN 0893-3952

Reis, J. S., Pusztai, L. (2011) Breast Cancer 2 Gene expression profiling in breast cancer: classification, prognostication, and prediction. LANCET, 378 (9805). pp. 1812-1823. ISSN 0140-6736

Patani, N., Barbashina, V., Lambros, M. B. K., Gauthier, A., Mansour, M., Mackay, A., Reis, J. S. (2011) Direct evidence for concurrent morphological and genetic heterogeneity in an invasive ductal carcinoma of triple-negative phenotype. JOURNAL OF CLINICAL PATHOLOGY, 64 (9). pp. 822-828. ISSN 0021-9746

Dedes, K. J., Natrajan, R., Lambros, M. B., Geyer, F. C., Lopez-Garcia, M. A., Savage, K., Jones, R. L., Reis-Filho, J. S. (2011) Down-regulation of the miRNA master regulators Drosha and Dicer is associated with specific subgroups of breast cancer. EUROPEAN JOURNAL OF CANCER , 47 (1). pp. 138-150. ISSN 0959-8049

Rajan, N., Elliott, R., Clewes, O., Mackay, A., Reis-Filho, J. S., Burn, J., Langtry, J., Sieber-Blum, M., Lord, C. J., Ashworth, A. (2011) Dysregulated TRK signalling is a therapeutic target in CYLD defective tumours. ONCOGENE, 30 (41). pp. 4243-4260. ISSN 0950-9232

Henry, L. A., Johnson, D. A., Sarrio, D., Lee, S., Quinlan, P. R., Crook, T., Thompson, A. M., Reis, J. S., Isacke, C. M. (2011) Endoglin expression in breast tumor cells suppresses invasion and metastasis and correlates with improved clinical outcome. ONCOGENE, 30 (9). pp. 1046-1058. ISSN 0950-9232

Xu, H. L., Yan, M., Patra, J., Natrajan, R., Yan, Y. Q., Swagemakers, S., Tomaszewski, J. M., Verschoor, S., Millar, E. K. A., van der Spek, P., Reis-Filho, J. S., Ramsay, R. G., O'Toole, S. A., McNeil, C. M., Sutherland, R. L., McKay, M. J., Fox, S. B. (2011) Enhanced RAD21 cohesin expression confers poor prognosis and resistance to chemotherapy in high grade luminal, basal and HER2 breast cancers. BREAST CANCER RESEARCH, 13 (1). ISSN 1465-5411

Sharpe, R., Pearson, A., Herrera-Abreu, M. T., Johnson, D., Mackay, A., Welti, J. C., Natrajan, R., Reynolds, A. R., Reis, J. S., Ashworth, A., Turner, N. C. (2011) FGFR Signaling Promotes the Growth of Triple-Negative and Basal-Like Breast Cancer Cell Lines Both In Vitro and In Vivo. CLINICAL CANCER RESEARCH, 17 (16). pp. 5275-5286. ISSN 1078-0432

Wilkerson, P. M., Dedes, K. J., Wetterskog, D., Mackay, A., Lambros, M. B., Mansour, M., Frankum, J., Lord, C. J., Natrajan, R., Ashworth, A., Reis-Filho, J. S. (2011) Functional characterization of EMSY gene amplification in human cancers. JOURNAL OF PATHOLOGY, 225 (1). pp. 29-42. ISSN 0022-3417

Brough, R., Frankum, J. R., Sims, D., Mackay, A., Mendes-Pereira, A. M., Bajrami, I., Costa-Cabral, S., Rafiq, R., Ahmad, A. S., Cerone, M. A., Natrajan, R., Sharpe, R., Shiu, K. K., Wetterskog, D., Dedes, K. J., Lambros, M. B., Rawjee, T., Linardopoulos, S., Reis, J. S., Turner, N. C., Lord, C. J., Ashworth, A. (2011) Functional Viability Profiles of Breast Cancer. CANCER DISCOVERY , 1 (3). pp. 260-273. ISSN 2159-8274

Robinson, D. R., Kalyana-Sundaram, S., Wu, Y. M., Shankar, S., Cao, X. H., Ateeq, B., Asangani, I. A., Iyer, M., Maher, C. A., Grasso, C. S., Lonigro, R. J., Quist, M., Siddiqui, J., Mehra, R., Jing, X. J., Giordano, T. J., Sabel, M. S., Kleer, C. G., Palanisamy, N., Natrajan, R., Lambros, M. B., Reis-Filho, J. S., Kumar-Sinha, C., Chinnaiyan, A. M. (2011) Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer. NATURE MEDICINE, 17 (12). 1646-U163. ISSN 1078-8956

Ashworth, A., Lord, C. J., Reis, J. S. (2011) Genetic Interactions in Cancer Progression and Treatment. CELL, 145 (1). pp. 30-38. ISSN 0092-8674

Tan, D. S. P., Iravani, M., McCluggage, W. G., Lambros, M. B. K., Milanezi, F., Mackay, A., Gourley, C., Geyer, F. C., Vatcheva, R., Millar, J., Thomas, K., Natrajan, R., Savage, K., Fenwick, K., Williams, A., Jameson, C., El-Bahrawy, M., Gore, M. E., Gabra, H., Kaye, S. B., Ashworth, A., Reis, J. S. (2011) Genomic Analysis Reveals the Molecular Heterogeneity of Ovarian Clear Cell Carcinomas. CLINICAL CANCER RESEARCH, 17 (6). pp. 1521-1534. ISSN 1078-0432

Loveday, C., Turnbull, C., Ramsay, E., Hughes, D., Ruark, E., Frankum, J. R., Bowden, G., Kalmyrzaev, B., Warren-Perry, M., Snape, K., Adlard, J. W., Barwell, J., Berg, J., Brady, A. F., Brewer, C., Brice, G., Chapman, C., Cook, J., Davidson, R., Donaldson, A., Douglas, F., Greenhalgh, L., Henderson, A., Izatt, L., Kumar, A., Lalloo, F., Miedzybrodzka, Z., Morrison, P. J., Paterson, J., Porteous, M., Rogers, M. T., Shanley, S., Walker, L., Eccles, D., Evans, D. G., Renwick, A., Seal, S., Lord, C. J., Ashworth, A., Reis-Filho, J. S., Antoniou, A. C., Rahman, N., Breast Canc, Susceptibility (2011) Germline mutations in RAD51D confer susceptibility to ovarian cancer. NATURE GENETICS, 43 (9). 879-U90. ISSN 1061-4036

Lambros, M. B. K., Wilkerson, P. M., Natrajan, R., Patani, N., Pawar, V., Vatcheva, R., Mansour, M., Laschet, M., Oelze, B., Orr, N., Muller, S., Reis, J. S. (2011) High-throughput detection of fusion genes in cancer using the Sequenom MassARRAY platform. LABORATORY INVESTIGATION, 91 (10). pp. 1491-1501. ISSN 0023-6837

Tanas, M. R., Sboner, A., Oliveira, A. M., Erickson-Johnson, M. R., Hespelt, J., Hanwright, P. J., Flanagan, J., Luo, Y. L., Fenwick, K., Natrajan, R., Mitsopoulos, C., Zvelebil, M., Hoch, B. L., Weiss, S. W., Debiec-Rychter, M., Sciot, R., West, R. B., Lazar, A. J., Ashworth, A., Reis, J. S., Lord, C. J., Gerstein, M. B., Rubin, M. A., Rubin, B. P. (2011) Identification of a Disease-Defining Gene Fusion in Epithelioid Hemangioendothelioma. Science Translational Medicine, 3 (98). ISSN 1946-6242

Ha, K. C. H., Lalonde, E., Li, L. L., Cavallone, L., Natrajan, R., Lambros, M. B., Mitsopoulos, C., Hakas, J., Kozarewa, I., Fenwick, K., Lord, C. J., Ashworth, A., Vincent-Salomon, A., Basik, M., Reis, J. S., Majewski, J., Foulkes, W. D. (2011) Identification of gene fusion transcripts by transcriptome sequencing in BRCA1-mutated breast cancers and cell lines. Bmc Medical Genomics, 4 . ISSN 1755-8794

Hungermann, D., Schmidt, H., Natrajan, R., Tidow, N., Poos, K., Reis, J. S., Brandt, B., Buerger, H., Korsching, E. (2011) Influence of whole arm loss of chromosome 16q on gene expression patterns in oestrogen receptor-positive, invasive breast cancer. JOURNAL OF PATHOLOGY, 224 (4). pp. 517-528. ISSN 0022-3417

Mackay, A., Weigelt, B., Grigoriadis, A., Kreike, B., Natrajan, R., A'Hern, R., Tan, D. S. P., Dowsett, M., Ashworth, A., Reis-Filho, J. S. (2011) Microarray-Based Class Discovery for Molecular Classification of Breast Cancer: Analysis of Interobserver Agreement. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 103 (8). pp. 662-673. ISSN 0027-8874

Jones, R. L., Rojo, F., A'Hern, R., Villena, N., Salter, J., Corominas, J. M., Servitja, S., Smith, I. E., Rovira, A., Reis-Filho, J. S., Dowsett, M., Albanell, J. (2011) Nuclear NF-kappa B/p65 expression and response to neoadjuvant chemotherapy in breast cancer. JOURNAL OF CLINICAL PATHOLOGY, 64 (2). pp. 130-135. ISSN 0021-9746

Ragazzi, M., Biase, D., Betts, C. M., Farnedi, A., Ramadan, S. S., Tallini, G., Reis, J. S., Eusebi, V. (2011) Oncocytic carcinoma of the breast: frequency, morphology and follow-up. HUMAN PATHOLOGY, 42 (2). pp. 166-175. ISSN 0046-8177

Vargas, A. C., Reis, J. S., Lakhani, S. R. (2011) Phenotype-Genotype Correlation in Familial Breast Cancer. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, 16 (1). pp. 27-40. ISSN 1083-3021

Nguyen, D. H., Oketch-Rabah, H. A., Illa-Bochaca, I., Geyer, F. C., Reis-Filho, J. S., Mao, J. H., Ravani, S. A., Zavadi, J., Borowsky, A. D., Jerry, D. J., Dunphy, K. A., Seo, J. H., Haslam, S., Medina, D., Barcellos-Hoff, M. H. (2011) Radiation Acts on the Microenvironment to Affect Breast Carcinogenesis by Distinct Mechanisms that Decrease Cancer Latency and Affect Tumor Type. CANCER CELL, 19 (5). pp. 640-651. ISSN 1535-6108

Dedes, K. J., Wilkerson, P. M., Wetterskog, D., Weigelt, B., Ashworth, A., Reis-Filho, J. S. (2011) Synthetic lethality of PARP inhibition in cancers lacking BRCA1 and BRCA2 mutations. CELL CYCLE, 10 (8). pp. 1192-1199. ISSN 1538-4101

Wansbury, O., Mackay, A., Kogata, N., Mitsopoulos, C., Kendrick, H., Davidson, K., Ruhrberg, C., Reis, J. S., Smalley, M. J., Zvelebil, M., Howard, B. A. (2011) Transcriptome analysis of embryonic mammary cells reveals insights into mammary lineage establishment. BREAST CANCER RESEARCH, 13 (4). ISSN 1465-5411

Lacroix-Triki, M., Geyer, F. C., Lambros, M. B., Savage, K., Ellis, I. O., Lee, A. H. S., Reis-Filho, J. S. (2010) beta-catenin/Wnt signalling pathway in fibromatosis, metaplastic carcinomas and phyllodes tumours of the breast. MODERN PATHOLOGY, 23 (11). pp. 1438-1448. ISSN 0893-3952

Abdel-Fatah, T. M., Powe, D. G., Agboola, J., Adamowicz-Brice, M., Blamey, R. W., Lopez-Garcia, M. A., Green, A. R., Reis-Filho, J. S., Ellis, I. O. (2010) The biological, clinical and prognostic implications of p53 transcriptional pathways in breast cancers. JOURNAL OF PATHOLOGY, 220 (4). pp. 419-434. ISSN 0022-3417

Molyneux, G., Geyer, F. C., Magnay, F., McCarthy, A., Kendrick, H., Natrajan, R., MacKay, A., Grigoriadis, A., Tutt, A., Ashworth, A., Reis-Filho, J. S., Smalley, M. J. (2010) BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells. CELL STEM CELL, 7 (3). pp. 403-417. ISSN 1934-5909

Weigelt, B., Mackay, A., A'hern, R., Natrajan, R., Tan, D. S. P., Dowsett, M., Ashworth, A., Reis-Filho, J. S. (2010) Breast cancer molecular profiling with single sample predictors: a retrospective analysis. LANCET ONCOLOGY, 11 (4). pp. 339-349. ISSN 1470-2045

Simpson, P. T., Reis-Filho, J. S., Lakhani, S. R. (2010) Breast pathology: beyond morphology. SEMINARS IN DIAGNOSTIC PATHOLOGY, 27 (1). pp. 91-96. ISSN 0740-2570

Frio, T. R., Lavoie, J., Hamel, N., Geyer, F. C., Kushner, Y. B., Novak, D. J., Wark, L., Capelli, C., Reis-Filho, J. S., Mai, S., Pastinen, T., Tischkowitz, M. D., Marcus, V. A., Foulkes, W. D. (2010) Brief Report: Homozygous BUB1B Mutation and Susceptibility to Gastrointestinal Neoplasia. NEW ENGLAND JOURNAL OF MEDICINE, 363 (27). pp. 2628-2637. ISSN 0028-4793

Klingbeil, P., Natrajan, R., Everitt, G., Vatcheva, R., Marchio, C., Palacios, J., Buerger, H., Reis-Filho, J. S., Isacke, C. M. (2010) CD44 is overexpressed in basal-like breast cancers but is not a driver of 11p13 amplification. BREAST CANCER RESEARCH AND TREATMENT, 120 (1). pp. 95-109. ISSN 0167-6806

Rakha, E. A., Patel, A., Powe, D. G., Benhasouna, A., Green, A. R., Lambros, M. B., Reis-Filho, J. S., Ellis, I. O. (2010) Clinical and Biological Significance of E-cadherin Protein Expression in Invasive Lobular Carcinoma of the Breast. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 34 (10). pp. 1472-1479. ISSN 0147-5185

McCluggage, W. G., Harley, I., Houghton, J. P., Geyer, F. C., MacKay, A., Reis-Filho, J. S. (2010) Composite cervical adenocarcinoma composed of adenoma malignum and gastric type adenocarcinoma (dedifferentiated adenoma malignum) in a patient with Peutz Jeghers syndrome. JOURNAL OF CLINICAL PATHOLOGY, 63 (10). pp. 935-941. ISSN 0021-9746

Dedes, K. J., Lopez-Garcia, M., Geyer, F. C., Lambros, M. B. K., Savage, K., Vatcheva, R., Wilkerson, P., Wetterskog, D., Lacroix-Triki, M., Natrajan, R., Reis-Filho, J. S. (2010) Cortactin gene amplification and expression in breast cancer: a chromogenic in situ hybridisation and immunohistochemical study. BREAST CANCER RESEARCH AND TREATMENT, 124 (3). pp. 653-666. ISSN 0167-6806

Turner, N., Pearson, A., Sharpe, R., Lambros, M., Geyer, F., Lopez-Garcia, M. A., Natrajan, R., Marchio, C., Iorns, E., Mackay, A., Gillett, C., Grigoriadis, A., Tutt, A., Reis-Filho, J. S., Ashworth, A. (2010) FGFR1 Amplification Drives Endocrine Therapy Resistance and Is a Therapeutic Target in Breast Cancer. CANCER RESEARCH, 70 (5). pp. 2085-2094. ISSN 0008-5472

Geyer, F. C., Lambros, M. B. K., Natrajan, R., Mehta, R., Mackay, A., Savage, K., Parry, S., Ashworth, A., Badve, S., Reis-Filho, J. S. (2010) Genomic and immunohistochemical analysis of adenosquamous carcinoma of the breast. MODERN PATHOLOGY, 23 (7). pp. 951-960. ISSN 0893-3952

Natrajan, R., Weigelt, B., Mackay, A., Geyer, F. C., Grigoriadis, A., Tan, D. S. P., Jones, C., Lord, C. J., Vatcheva, R., Rodriguez-Pinilla, S. M., Palacios, J., Ashworth, A., Reis-Filho, J. S. (2010) An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers. BREAST CANCER RESEARCH AND TREATMENT, 121 (3). pp. 575-589. ISSN 0167-6806

Turner, N., Lambros, M. B., Horlings, H. M., Pearson, A., Sharpe, R., Natrajan, R., Geyer, F. C., van Kouwenhove, M., Kreike, B., Mackay, A., Ashworth, A., de Vijver, M. J., Reis-Filho, J. S. (2010) Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets. ONCOGENE, 29 (14). pp. 2013-2023. ISSN 0950-9232

Hudson, T. J., Anderson, W., Aretz, A., Barker, A. D., Bell, C., Bernabe, R. R., Bhan, M. K., Calvo, F., Eerola, I., Gerhard, D. S., Guttmacher, A., Guyer, M., Hemsley, F. M., Jennings, J. L., Kerr, D., Klatt, P., Kolar, P., Kusuda, J., Lane, D. P., Laplace, F., Lu, Y., Nettekoven, G., Ozenberger, B., Peterson, J., Rao, T. S., Remacle, J., Schafer, A. J., Shibata, T., Stratton, M. R., Vockley, J. G., Watanabe, K., Yang, H., Yuen, M. M. F., Knoppers, M., Bobrow, M., Cambon-Thomsen, A., Dressler, L. G., Dyke, S. O. M., Joly, Y., Kato, K., Kennedy, K. L., Nicolas, P., Parker, M. J., Rial-Sebbag, E., Romeo-Casabona, C. M., Shaw, K. M., Wallace, S., Wiesner, G. L., Zeps, N., Lichter, P., Biankin, A. V., Chabannon, C., Chin, L., Clement, B., de Alava, E., Degos, F., Ferguson, M. L., Geary, P., Hayes, D. N., Johns, A. L., Nakagawa, H., Penny, R., Piris, M. A., Sarin, R., Scarpa, A., Shibata, T., van de Vijver, M., Futreal, P. A., Aburatani, H., Bayes, M., Bowtell, D. D. L., Campbell, P. J., Estivill, X., Grimmond, S. M., Gut, I., Hirst, M., Lopez-Otin, C., Majumder, P., Marra, M., Nakagawa, H., Ning, Z., Puente, X. S., Ruan, Y., Shibata, T., Stratton, M. R., Stunnenberg, H. G., Swerdlow, H., Velculescu, V. E., Wilson, R. K., Xue, H. H., Yang, L., Spellman, P. T., Bader, G. D., Boutros, P. C., Campbell, P. J., Flicek, P., Getz, G., Guigo, R., Guo, G., Haussler, D., Heath, S., Hubbard, T. J., Jiang, T., Jones, S. M., Li, Q., Lopez-Bigas, N., Luo, R., Pearson, J. V., Puente, X. S., Quesada, V., Raphael, B. J., Sander, C., Shibata, T., Speed, T. P., Stuart, J. M., Teague, J. W., Totoki, Y., Tsunoda, T., Valencia, A., Wheeler, D. A., Wu, H., Zhao, S., Zhou, G., Stein, L. D., Guigo, R., Hubbard, T. J., Joly, Y., Jones, S. M., Lathrop, M., Lopez-Bigas, N., Ouellette, B. F. F., Spellman, P. T., Teague, J. W., Thomas, G., Valencia, A., Yoshida, T., Kennedy, K. L., Axton, M., Dyke, S. O. M., Futreal, P. A., Gunter, C., Guyer, M., McPherson, J. D., Miller, L. J., Ozenberger, B., Kasprzyk, A., Zhang, J., Haider, S. A., Wang, J., Yung, C. K., Cross, A., Liang, Y., Gnaneshan, S., Guberman, J., Hsu, J., Bobrow, M., Chalmers, D. R. C., Hasel, K. W., Joly, Y., Kaan, T. S. H., Kennedy, K. L., Knoppers, B. M., Lowrance, W. W., Masui, T., Nicolas, P., Rial-Sebbag, E., Rodriguez, L. L., Vergely, C., Yoshida, T., Grimmond, S. M., Biankin, A. V., Bowtell, D. D. L., Cloonan, N., Defazio, A., Eshleman, J. R., Etemadmoghadam, D., Gardiner, B. A., Kench, J. G., Scarpa, A., Sutherland, R. L., Tempero, M. A., Waddell, N. J., Wilson, P. J., Gallinger, S., Tsao, M., Shaw, P. A., Petersen, G. M., Mukhopadhyay, D., Chin, L., DePinho, R. A., Thayer, S., Muthuswamy, L., Shazand, K., Beck, T., Sam, M., Timms, L., Ballin, V., Lu, Y., Ji, J., Zhang, X., Chen, F., Hu, X., Zhou, G., Yang, Q., Tian, G., Zhang, L., Xing, X., Li, X., Zhu, Z., Yu, Y., Yu, J., Yang, H., Lathrop, M., Tost, J., Brennan, P., Holcatova, I., Zaridze, D., Brazma, A., Egevad, L., Prokhortchouk, E., Banks, R. E., Uhlen, M., Cambon-Thomsen, A., Viksna, J., Ponten, F., Skryabin, K., Stratton, M. R., Futreal, P. A., Birney, E., Borg, A., Borresen-Dale, A., Caldas, C., Foekens, J. A., Martin, S., Reis-Filho, J. S., Richardson, A. L., Sotiriou, C., Stunnenberg, H. G., Thomas, G., van de Vijver, M., van't Veer, L., Birnbaum, D., Blanche, H., Boucher, P., Boyault, S., Chabannon, C., Gut, I., Masson-Jacquemier, J. D., Lathrop, M., Pauporte, I., Pivot, X., Vincent-Salomon, A., Tabone, E., Theillet, C., Thomas, G., Tost, J., Treilleux, I., Bioulac-Sage, P., Clement, B., Decaens, T., Degos, F., Franco, D., Gut, I., Gut, M., Heath, S., Lathrop, M., Samuel, D., Thomas, G., Zucman-Rossi, J., Lichter, P., Eils, R., Brors, B., Korbel, J. O., Korshunov, A., Landgraf, P., Lehrach, H., Pfister, S., Radlwimmer, B., Reifenberger, G., Taylor, M. D., von Kalle, C., Majumder, P. P., Sarin, R., Scarpa, A., Pederzoli, P., Lawlor, R. T., Delledonne, M., Bardelli, A., Biankin, A. V., Grimmond, S. M., Gress, T., Klimstra, D., Zamboni, G., Shibata, T., Nakamura, Y., Nakagawa, H., Kusuda, J., Tsunoda, T., Miyano, S., Aburatani, H., Kato, K., Fujimoto, A., Yoshida, T., Campo, E., Lopez-Otin, C., Estivill, X., Guigo, R., de Sanjose, S., Piris, M. A., Montserrat, E., Gonzalez-Diaz, M., Puente, X. S., Jares, P., Valencia, A., Himmelbaue, H., Quesada, V., Bea, S., Stratton, M. R., Futreal, P. A., Campbell, P. J., Vincent-Salomon, A., Richardson, A. L., Reis-Filho, J. S., van de Vijver, M., Thomas, G., Masson-Jacquemier, J. D., Aparicio, S., Borg, A., Borresen-Dale, A., Caldas, C., Foekens, J. A., Stunnenberg, H. G., van't Veer, L., Easton, D. F., Spellman, P. T., Martin, S., Chin, L., Collins, F. S., Compton, C. C., Ferguson, M. L., Getz, G., Gunter, C., Guyer, M., Hayes, D. N., Lander, E. S., Ozenberger, B., Penny, R., Peterson, J., Sander, C., Speed, T. P., Spellman, P. T., Wheeler, D. A., Wilson, R. K., Chin, L., Knoppers, B. M., Lander, E. S., Lichter, P., Stratton, M. R., Bobrow, M., Burke, W., Collins, F. S., DePinho, R. A., Easton, D. F., Futreal, P. A., Green, A. R., Guyer, M., Hamilton, S. R., Hubbard, T. J., Kallioniemi, O. P., Kennedy, K. L., Ley, T. J., Liu, E. T., Lu, Y., Majumder, P., Marra, M., Ozenberger, B., Peterson, J., Schafer, A. J., Spellman, P. T., Stunnenberg, H. G., Wainwright, B. J., Wilson, R. K., Yang, H., Int Canc Genome Consortium, [Group Author] (2010) International network of cancer genome projects. NATURE, 464 (7291). pp. 993-998. ISSN 0028-0836

Heidom, S. J., Milagre, C., Whittaker, S., Nourry, A., Niculescu-Duvas, I., Dhomen, N., Hussain, J., Reis-Filho, J. S., Springer, C. J., Pritchard, C., Marais, R. (2010) Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF. CELL, 140 (2). pp. 209-221. ISSN 0092-8674

Graeser, M., McCarthy, A., Lord, C. J., Savage, K., Hills, M., Salter, J., Orr, N., Parton, M., Smith, I. E., Reis-Filho, J. S., Dowsett, M., Ashworth, A., Turner, N. C. (2010) A Marker of Homologous Recombination Predicts Pathologic Complete Response to Neoadjuvant Chemotherapy in Primary Breast Cancer. CLINICAL CANCER RESEARCH, 16 (24). pp. 6159-6168. ISSN 1078-0432

Geyer, F. C., Weigelt, B., Natrajan, R., Lambros, M. B. K., de Blase, D., Vatcheva, R., Savage, K., Mackay, A., Ashworth, A., Reis-Filho, J. S. (2010) Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas. JOURNAL OF PATHOLOGY, 220 (5). pp. 562-573. ISSN 0022-3417

Reis, J. S., Weigelt, B., Fumagalli, D., Sotiriou, C. (2010) Molecular Profiling: Moving Away from Tumor Philately. Science Translational Medicine, 2 (47). ISSN 1946-6234

Weigelt, B., Geyer, F. C., Natrajan, R., Lopez-Garcia, M. A., Ahmad, A. S., Savage, K., Kreike, B., Reis-Filho, J. S. (2010) The molecular underpinning of lobular histological growth pattern: a genome-wide transcriptomic analysis of invasive lobular carcinomas and grade- and molecular subtype-matched invasive ductal carcinomas of no special type. JOURNAL OF PATHOLOGY, 220 (1). pp. 45-57. ISSN 0022-3417

Milagre, C., Dhomen, N., Geyer, F. C., Hayward, R., Lambros, M., Reis-Filho, J. S., Marais, R. (2010) A Mouse Model of Melanoma Driven by Oncogenic KRAS. CANCER RESEARCH, 70 (13). pp. 5549-5557. ISSN 0008-5472

Lacroix-Triki, M., Suarez, P. H., MacKay, A., Lambros, M. B., Natrajan, R., Savage, K., Geyer, F. C., Weigelt, B., Ashworth, A., Reis-Filho, J. S. (2010) Mucinous carcinoma of the breast is genomically distinct from invasive ductal carcinomas of no special type. JOURNAL OF PATHOLOGY, 222 (3). pp. 282-298. ISSN 0022-3417

Whittaker, S., Menard, D., Kirk, R., Ogilvie, L., Hedley, D., Zambon, A., Lopes, F., Preece, N., Manne, H., Rana, S., Lambros, M., Reis-Filho, J. S., Marais, R., Springer, C. J. (2010) A Novel, Selective, and Efficacious Nanomolar Pyridopyrazinone Inhibitor of (V600E)BRAF. CANCER RESEARCH, 70 (20). pp. 8036-8044. ISSN 0008-5472

Lambros, M. B., Natrajan, R., Geyer, F. C., Lopez-Garcia, M. A., Dedes, K. J., Savage, K., Lacroix-Triki, M., Jones, R. L., Lord, C. J., Linardopoulos, S., Ashworth, A., Reis-Filho, J. S. (2010) PPM1D gene amplification and overexpression in breast cancer: a qRT-PCR and chromogenic in situ hybridization study. MODERN PATHOLOGY, 23 (10). pp. 1334-1345. ISSN 0893-3952

Resetkova, E., Reis-Filho, J. S., Jain, R. K., Mehta, R., Thorat, M. A., Nakshatri, H., Badve, S. (2010) Prognostic impact of ALDH1 in breast cancer: a story of stem cells and tumor microenvironment. BREAST CANCER RESEARCH AND TREATMENT, 123 (1). pp. 97-108. ISSN 0167-6806

Abdel-Fatah, T. M. A., Powe, D. G., Ball, G., Lopez-Garcia, M. A., Habashy, H. O., Green, A. R., Reis-Filho, J. S., Ellis, I. O. (2010) Proposal for a modified grading system based on mitotic index and Bcl2 provides objective determination of clinical outcome for patients with breast cancer. JOURNAL OF PATHOLOGY, 222 (4). pp. 388-399. ISSN 0022-3417

Dedes, K. J., Wetterskog, D., Mendes-Pereira, A. M., Natrajan, R., Lambros, M. B., Geyer, F. C., Vatcheva, R., Savage, K., Mackay, A., Lord, C. J., Ashworth, A., Reis-Filho, J. S. (2010) PTEN Deficiency in Endometrioid Endometrial Adenocarcinomas Predicts Sensitivity to PARP Inhibitors. Science Translational Medicine, 2 (53). ISSN 1946-6234

Jones, R. L., Salter, J., A'Hern, R., Nerurkar, A., Parton, M., Reis-Filho, J. S., Smith, I. E., Dowsett, M. (2010) Relationship between oestrogen receptor status and proliferation in predicting response and long-term outcome to neoadjuvant chemotherapy for breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 119 (2). pp. 315-323. ISSN 0167-6806

Burrell, R. A., Juul, N., Johnston, S. R., Reis-Filho, J. S., Szallasi, Z., Swanton, C. (2010) Targeting Chromosomal Instability and Tumour Heterogeneity in HER2-Positive Breast Cancer. JOURNAL OF CELLULAR BIOCHEMISTRY, 111 (4). pp. 782-790. ISSN 0730-2312

Lopez-Garcia, M. A., Geyer, F. C., Natrajan, R., Kreike, B., Mackay, A., Grigoriadis, A., Reis-Filho, J. S., Weigelt, B. (2010) Transcriptomic analysis of tubular carcinomas of the breast reveals similarities and differences with molecular subtype-matched ductal and lobular carcinomas. JOURNAL OF PATHOLOGY, 222 (1). pp. 64-75. ISSN 0022-3417

Foulkes, W. D., Reis-Filho, J. S., Narod, S. A. (2010) Tumor size and survival in breast cancer-a reappraisal. NATURE REVIEWS CLINICAL ONCOLOGY, 7 (6). pp. 348-353. ISSN 1759-4774

Lancashire, L. J., Powe, D. G., Reis-Filho, J. S., Rakha, E., Lemetre, C., Weigelt, B., Abdel-Fatah, T. M., Green, A. R., Mukta, R., Blamey, R., Paish, E. C., Rees, R. C., Ellis, I. O., Ball, G. R. (2010) A validated gene expression profile for detecting clinical outcome in breast cancer using artificial neural networks. BREAST CANCER RESEARCH AND TREATMENT, 120 (1). pp. 83-93. ISSN 0167-6806

Stephens, P. J., McBride, D. J., Lin, M., Varela, I., Pleasance, E. D., Simpson, J. T., Stebbings, L. A., Leroy, C., Edkins, S., Mudie, L. J., Greenman, C. D., Jia, M., Latimer, C., Teague, J. W., Lau, K. W., Burton, J., Quail, M. A., Swerdlow, H., Churcher, C., Natrajan, R., Sieuwerts, A. M., Martens, J. W. M., Silver, D. P., Langerod, A., Russnes, H. E. G., Foekens, J. A., Reis-Filho, J. S., van't Veer, L., Richardson, A. L., Borresen-Dale, A., Campbell, P. J., Futreal, P. A., Stratton, M. R. (2009) Complex landscapes of somatic rearrangement in human breast cancer genomes. NATURE, 462 (7276). 1005-U60. ISSN 0028-0836

McCarthy, A., Lord, C. J., Savage, K., Grigoriadis, A., Smith, D. P., Weigelt, B., Reis-Filho, J. S., Ashworth, A. (2009) Conditional deletion of the Lkb1 gene in the mouse mammary gland induces tumour formation. JOURNAL OF PATHOLOGY, 219 (3). pp. 306-316. ISSN 0022-3417

Marchio, C., Lambros, M. B., Gugliotta, P., Di Cantogno, L. V., Botta, C., Pasini, B., Tan, D. S. P., Mackay, A., Fenwick, K., Tamber, N., Bussolati, G., Ashworth, A., Reis-Filho, J. S., Sapino, A. (2009) Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridization and microarray-based CGH analysis. JOURNAL OF PATHOLOGY, 219 (1). pp. 16-24. ISSN 0022-3417

Bax, D. A., Gaspar, N., Little, S. E., Marshall, L., Perryman, L., Regairaz, M., Viana-Pereira, M., Vuononvirta, R., Sharp, S. Y., Reis-Filho, J. S., Stavale, J. N., Al-Sarraj, S., Reis, R. M., Vassal, G., Pearson, A. D. J., Hargrave, D., Ellison, D. W., Workman, P., Jones, C. (2009) EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines. CLINICAL CANCER RESEARCH, 15 (18). pp. 5753-5761. ISSN 1078-0432

Vuononvirta, R., Sebire, N. J., Messahel, B., Perusinghe, N., Reis-Filho, J. S., Pritchard-Jones, K., Vujanic, G. M., Jones, C. (2009) Expression of Hepatocyte Growth Factor and Its Receptor Met in Wilms' Tumors and Nephrogenic Rests Reflects Their Roles in Kidney Development. CLINICAL CANCER RESEARCH, 15 (8). pp. 2723-2730. ISSN 1078-0432

Martinho, O., Longatto-Filho, A., Lambros, M. B. K., Martins, A., Pinheiro, C., Silva, A., Pardal, F., Amorim, J., Mackay, A., Milanezi, F., Tamber, N., Fenwick, K., Ashworth, A., Reis-Filho, J. S., Lopes, J. M., Reis, R. M. (2009) Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas. BRITISH JOURNAL OF CANCER, 101 (6). pp. 973-982. ISSN 0007-0920

Geyer, F. C., Decker, T., Reis-Filho, J. S. (2009) Genome-wide expression profiling as a clinical tool. PATHOLOGE, 30 (2). pp. 141-146. ISSN 0172-8113

Westbury, C. B., Reis-Filho, J. S., Dexter, T., Mahler-Araujo, B., Fenwick, K., Iravani, M., Grigoriadis, A., Parry, S., Robertson, D., Mackay, A., Ashworth, A., Yarnold, J. R., Isacke, C. M. (2009) Genome-wide transcriptomic profiling of microdissected human breast tissue reveals differential expression of KIT (c-Kit, CD117) and oestrogen receptor-alpha (ER alpha) in response to therapeutic radiation. JOURNAL OF PATHOLOGY, 219 (1). pp. 131-140. ISSN 0022-3417

Lambros, M. B. K., Tan, D. S. P., Jones, R. L., Vatcheva, R., Savage, K., Tamber, N., Fenwick, K., Mackay, A., Ashworth, A., Reis-Filho, J. S. (2009) Genomic profile of a secretory breast cancer with an ETV6-NTRK3 duplication. JOURNAL OF CLINICAL PATHOLOGY, 62 (7). pp. 604-612. ISSN 0021-9746

Mackay, A., Tamber, N., Fenwick, K., Iravani, M., Grigoriadis, A., Dexter, T., Lord, C. J., Reis-Filho, J. S., Ashworth, A. (2009) A high-resolution integrated analysis of genetic and expression profiles of breast cancer cell lines. BREAST CANCER RESEARCH AND TREATMENT, 118 (3). pp. 481-498. ISSN 0167-6806

Packer, L. M., East, P., Reis-Filho, J. S., Marais, R. (2009) Identification of direct transcriptional targets of V600EBRAF/MEK signalling in melanoma. PIGMENT CELL & MELANOMA RESEARCH, 22 (6). pp. 785-798. ISSN 1755-1471

Iorns, E., Lord, C. J., Grigoriadis, A., McDonald, S., Fenwick, K., MacKay, A., Mein, C. A., Natrajan, R., Savage, K., Tamber, N., Reis-Filho, J. S., Turner, N. C., Ashworth, A. (2009) Integrated Functional, Gene Expression and Genomic Analysis for the Identification of Cancer Targets. PLOS ONE, 4 (4). ISSN 1932-6203

Natrajan, R., Lambros, M. B. K., Geyer, F. C., Marchio, C., Tan, D. S. P., Vatcheva, R., Shiu, K. K., Hungermann, D., Rodriguez-Pinilla, S. M., Palacios, J., Ashworth, A., Buerger, H., Reis-Filho, J. S. (2009) Loss of 16q in High Grade Breast Cancer is Associated with Estrogen Receptor Status: Evidence for Progression in Tumors with a Luminal Phenotype? GENES CHROMOSOMES & CANCER, 48 (4). pp. 351-365. ISSN 1045-2257

Weigelt, B., Kreike, B., Reis-Filho, J. S. (2009) Metaplastic breast carcinomas are basal-like breast cancers: a genomic profiling analysis. BREAST CANCER RESEARCH AND TREATMENT, 117 (2). pp. 273-280. ISSN 0167-6806

Geyer, F. C., Kushner, Y. B., Lambros, M. B., Natrajan, R., Mackay, A., Tamber, N., Fenwick, K., Purnell, D., Ashworth, A., Walker, R. A., Reis-Filho, J. S. (2009) Microglandular adenosis or microglandular adenoma? A molecular genetic analysis of a case associated with atypia and invasive carcinoma. HISTOPATHOLOGY, 55 (6). pp. 732-743. ISSN 0309-0167

Marchio, C., Iravan, M., Natrajan, R., Lambros, M. B. K., Geyer, F. C., Savage, K., Parry, S., Tamber, N., Fenwick, K., Mackay, A., Schmitt, F. C., Bussolati, G., Ellis, I., Ashworth, A., Sapino, A., Reis-Filho, J. S. (2009) Mixed micropapillary-ductal carcinomas of the breast: a genomic and immunohistochemical analysis of morphologically distinct components. JOURNAL OF PATHOLOGY, 218 (3). pp. 301-315. ISSN 0022-3417

Weigelt, B., Geyer, F. C., Horlings, H. M., Kreike, B., Halfwerk, H., Reis-Filho, J. S. (2009) Mucinous and neuroendocrine breast carcinomas are transcriptionally distinct from invasive ductal carcinomas of no special type. MODERN PATHOLOGY, 22 (11). pp. 1401-1414. ISSN 0893-3952

Reis-Filho, J. S. (2009) Next-generation sequencing. BREAST CANCER RESEARCH, 11 (Suppl. 3). ISSN 1465-5411

Dhomen, N., Reis-Filho, J. S., Dias, S. D., Hayward, R., Savage, K., Delmas, V., Larue, L., Pritchard, C., Marais, R. (2009) Oncogenic Braf Induces Melanocyte Senescence and Melanoma in Mice. CANCER CELL, 15 (4). pp. 294-303. ISSN 1535-6108

Tan, D. S. P., Lambros, M. B. K., Rayter, S., Natrajan, R., Vatcheva, R., Gao, Q., Marchio, C., Geyer, F. C., Savage, K., Parry, S., Fenwick, K., Tamber, N., Mackay, A., Dexter, T., Jameson, C., McCluggage, W. G., Williams, A., Graham, A., Faratian, D., El-Bahrawy, M., Paige, A. J., Gabra, H., Gore, M. E., Zvelebil, M., Lord, C. J., Kaye, S. B., Ashworth, A., Reis-Filho, J. S. (2009) PPM1D Is a Potential Therapeutic Target in Ovarian Clear Cell Carcinomas. CLINICAL CANCER RESEARCH, 15 (7). pp. 2269-2280. ISSN 1078-0432

Jones, R. L., Salter, J., A'Hern, R., Nerurkar, A., Parton, M., Reis-Filho, J. S., Smith, I. E., Dowsett, M. (2009) The prognostic significance of Ki67 before and after neoadjuvant chemotherapy in breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 116 (1). pp. 53-68. ISSN 0167-6806

Rocha, R. M., Nunes, C. B., Sanches, F. S. F., Rocha, G. F. S., de Oliveira, F. N., Reis-Filho, J. S., Lambros, M. B., Gobbi, H. (2009) RABBIT ANTIBODIES FOR HORMONE RECEPTORS AND HER2 EVALUATION IN BREAST CANCER. REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, 55 (2). pp. 163-168. ISSN 0104-4230

Natrajan, R., Lambros, M. B., Rodriguez-Pinilla, S. M., Moreno-Bueno, G., Tan, D. S. P., Marchio, C., Vatcheva, R., Rayter, S., Mahler-Araujo, B., Fulford, L. G., Hungermann, D., Mackay, A., Grigoriadis, A., Fenwick, K., Tamber, N., Hardisson, D., Tutt, A., Palacios, J., Lord, C. J., Buerger, H., Ashworth, A., Reis-Filho, J. S. (2009) Tiling Path Genomic Profiling of Grade 3 Invasive Ductal Breast Cancers. CLINICAL CANCER RESEARCH, 15 (8). pp. 2711-2722. ISSN 1078-0432

Rakha, E. A., Elsheikh, S. E., Aleskandarany, M. A., Habashi, H. O., Green, A. R., Powe, D. G., El-Sayed, M. E., Benhasouna, A., Brunet, J. S., Akslen, L. A., Evans, A. J., Blamey, R., Reis-Filho, J. S., Foulkes, W. D., Ellis, I. O. (2009) Triple-Negative Breast Cancer: Distinguishing between Basal and Nonbasal Subtypes. CLINICAL CANCER RESEARCH, 15 (7). pp. 2302-2310. ISSN 1078-0432

Viana-Pereira, M., Lopes, J. M., Little, S., Milanezi, F., Basto, D., Pardal, F., Jones, C., Reis-Filho, R. M. (2008) Analysis of EGFR overexpression, EGFR gene amplification and the EGFRvIII mutation in Portuguese high-grade gliomas. ANTICANCER RESEARCH, 28 (2A). pp. 913-920. ISSN 0250-7005

Elsheikh, S. E., Green, A. R., Rakha, E. A., Samaka, R. M., Ammar, A. A., Powe, D., Reis-Filho, J. S., Ellis, I. O. (2008) Caveolin 1 and caveolin 2 are associated with breast cancer basal-like and triple-negative immunophenotype. BRITISH JOURNAL OF CANCER, 99 (2). pp. 327-334. ISSN 0007-0920

Elsheikh, S., Green, A. R., Aleskandarany, M. A., Grainge, M., Paish, C. E., Lambros, M. B. K., Reis, J. S., Ellis, I. O. (2008) CCND1 amplification and cyclin D1 expression in breast cancer and their relation with proteomic subgroups and patient outcome. BREAST CANCER RESEARCH AND TREATMENT, 109 (2). pp. 325-335. ISSN 0167-6806

Nunes, C. B., Rocha, R. M., Reis-Filho, J. S., Lambros, M. B., Rocha, G. F. S., Sanches, F. S. F., Oliveira, F. N., Gobbi, H. (2008) Comparative analysis of six different antibodies against Her2 including the novel rabbit monoclonal antibody (SP3) and chromogenic in situ hybridisation in breast carcinomas. JOURNAL OF CLINICAL PATHOLOGY, 61 (8). pp. 934-938. ISSN 0021-9746

Natrajan, R., Warren, W., Messahel, B., Reis-Filho, J. S., Brundler, M. A., Dome, J. S., Grundy, P. E., Vujanic, G., Pritchard-Jones, K., Jones, C. (2008) Complex patterns of chromosome 9 alterations including the p16(INK4a) locus in Wilms tumours. JOURNAL OF CLINICAL PATHOLOGY, 61 (1). pp. 95-102. ISSN 0021-9746

Savage, K., Leung, S., Todd, S. K., Brown, L. A., Jones, R. L., Robertson, D., James, M., Parry, S., Pinilla, S. M. R., Huntsman, D., Reis-Filho, J. S. (2008) Distribution and significance of caveolin 2 expression in normal breast and invasive breast cancer: an immunofluorescence and immunohistochemical analysis. BREAST CANCER RESEARCH AND TREATMENT, 110 (2). pp. 245-256. ISSN 0167-6806

Thorat, M. A., Marchio, C., Morimiya, A., Savage, K., Nakshatri, H., Reis-Filho, J. S., Badve, S. (2008) Forkhead box A1 expression in breast cancer is associated with luminal subtype and good prognosis. JOURNAL OF CLINICAL PATHOLOGY, 61 (3). pp. 327-332. ISSN 0021-9746

Arriola, E., Marchio, C., Tan, D. S., Drury, S. C., Lambros, M. B., Natrajan, R., Rodriguez-Pinilla, S. M., Mackay, A., Tamber, N., Fenwick, K., Jones, C., Dowsett, M., Ashworth, A., Reis-Filho, J. S. (2008) Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines. LABORATORY INVESTIGATION, 88 (5). pp. 491-503. ISSN 0023-6837

Marchio, C., Iravani, M., Natrajan, R., Lambros, M. B., Savage, K., Tamber, N., Fenwick, K., Mackay, A., Senetta, R., Di Palma, S., Schmitt, F. C., Bussolati, G., Ellis, I. O., Ashworth, A., Sapino, A., Reis-Filho, J. S. (2008) Genomic and immunophenotypical characterization of pure micropapillary carcinomas of the breast. JOURNAL OF PATHOLOGY, 215 (4). pp. 398-410. ISSN 0022-3417

Marchio, C., Natrajan, R., Shiu, K. K., Lambros, M. B. K., Rodriguez-Pinilla, S. M., Tan, D. S. P., Lord, C. J., Hungermann, D., Fenwick, K., Tamber, N., Mackay, A., Palacios, J., Sapino, A., Buerger, H., Ashworth, A., Reis-Filho, J. S. (2008) The genomic profile of HER2-amplified breast cancers: the influence of ER status. JOURNAL OF PATHOLOGY, 216 (4). pp. 399-407. ISSN 0022-3417

Reis-Filho, J. S., Natrajan, R., Vatcheva, R., Lambros, M. B. K., Marcho, C., Mahler-Araujo, B., Paish, C., Hodi, Z., Eusebi, V., Ellis, I. O. (2008) Is acinic cell carcinoma a variant of secretory carcinoma? A FISH study using ETV6 'split apart' probes. HISTOPATHOLOGY, 52 (7). pp. 840-846. ISSN 0309-0167

Simpson, P. T., ReIs-Filho, J. S., Lambros, M. B. K., Jones, C., Steele, D., Mackay, A., Iravani, M., Fenwick, K., Dexter, T., Jones, A., Reid, L., Da Silva, L., Shin, S. J., Hardisson, D., Ashworth, A., Schmitt, F. C., Palacios, J., Lakhani, S. R. (2008) Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas. JOURNAL OF PATHOLOGY, 215 (3). pp. 231-244. ISSN 0022-3417

Abdel-Fatah, T. M. A., Powe, D. G., Hodi, Z., Reis-Filho, J. S., Lee, A. H. S., Ellis, I. O. (2008) Morphologic and molecular evolutionary pathways of low nuclear grade invasive breast cancers and their putative precursor lesions: Further evidence to support the concept of low nuclear grade breast neoplasia family. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 32 (4). pp. 513-523. ISSN 0147-5185

Robertson, D., Savage, K., Reis-Filho, J. S., Isacke, C. M. (2008) Multiple immunofluorescence labelling of formalin-fixed paraffin-embedded (FFPE) tissue. BMC CELL BIOLOGY, 9 . ISSN 1471-2121

Parry, S., Savage, K., Marchio, C., Reis-Filho, J. S. (2008) Nestin is expressed in basal-like and triple negative breast cancers. JOURNAL OF CLINICAL PATHOLOGY, 61 (9). pp. 1045-1050. ISSN 0021-9746

Vuononvirta, R., Sebire, N. J., Dallosso, A. R., Reis-Filho, J. S., Williams, R. D., Mackay, A., Fenwick, K., Grigoriadis, A., Ashworth, A., Pritchard-Jones, K., Brown, K. W., Vujanic, G. M., Jones, C. (2008) Perilobar Nephrogenic Rests Are Nonobligate Molecular Genetic Precursor Lesions of Insulin-Like Growth Factor-II-Associated Wilms Tumors. CLINICAL CANCER RESEARCH, 14 (23). pp. 7635-7644. ISSN 1078-0432

Mahler-Araujo, B., Savage, K., Parry, S., Reis-Filho, J. S. (2008) Reduction of E-cadherin expression is associated with non-lobular breast carcinomas of basal-like and triple negative phenotype. JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY, 61 (5). pp. 615-620. ISSN 1366-8714

Edwards, S. L., Brough, R., Lord, C. J., Natrajan, R., Vatcheva, R., Levine, D. A., Boyd, J., Reis-Filho, J. S., Ashworth, A. (2008) Resistance to therapy caused by intragenic deletion in BRCA2. NATURE, 451 (7182). pp. 1111-1115. ISSN 0028-0836

Tan, D. S. P., Marchio, C., Jones, R. L., Savage, K., Smith, I. E., Dowsett, M., Reis, J. S. (2008) Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients. BREAST CANCER RESEARCH AND TREATMENT, 111 (1). pp. 27-44. ISSN 0167-6806

Natrajan, R., Little, S. E., Sodha, N., Reis-Filho, J. S., Mackay, A., Fenwick, K., Ashworth, A., Perlman, E. J., Dome, J. S., Grundy, P. E., Pritchard-Jones, K., Jones. C. (2007) Analysis by array CGH of genomic changes associated with the progression or relapse of Wilms' tumour. JOURNAL OF PATHOLOGY, 211 (1). pp. 52-59. ISSN 0022-3417

Tischkowitz, M., Xia, B., Sabbaghian, N., Reis-Filho, J. S., Hamel, N., Li, G. L., van Beers, E. H., Li, L. L., Khalil, T., Quenneville, L. A., Omeroglu, A., Poll, A., Lepage, P., Wong, N., Nederlof, P. M., Ashworth, A., Tonin, P. N., Narod, S. A., Livingston, D. M., Foulkes, W. D. (2007) Analysis of PALB2/FANCN-associated breast cancer families. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 104 (16). pp. 6788-6793. ISSN 0027-8424

Briassouli, P., Chan, F., Savage, K., Reis-Filho, J. S., Linardopoulos, S. (2007) Aurora-A regulation of nuclear factor-kappa B signaling by phosphorylation of I kappa B alpha. CANCER RESEARCH, 67 (4). pp. 1689-1695. ISSN 0008-5472

Fulford, L. G., Reis-Filho, J. S., Ryder, K., Jones, C., Gillett, C. E., Hanby, A., Easton, D. F., Lakhani, S. R. (2007) Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival. BREAST CANCER RESEARCH, 9 (1). ISSN 1465-5411

Turner, N. C., Reis-Filho, J. S., Russell, A. M., Springall, R. J., Ryder, K., Steele, D., Savage, K., Gillett, C. E., Schmitt, F. C., Ashworth, A., Tutt, A. N. (2007) BRCA1 dysfunction in sporadic basal-like breast cancer. ONCOGENE, 26 (14). pp. 2126-2132. ISSN 0950-9232

Jones, C., Rodriguez-Pinilla, M., Lambros, M., Bax, D., Messahel, B., Vujanic, G. M., Reis-Filho, J. S., Pritchard-Jones, K. (2007) c-KIT overexpression, without gene amplification and mutation, in paediatric renal tumours. JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY, 60 (11). pp. 1226-1231. ISSN 1366-8714

Savage, K., Lambros, M. B. K., Robertson, D., Jones, R. L., Jones, C., Mackay, A., James, M., Hornick, J. L., Pereira, E. M., Milanezi, F., Fletcher, C. D. M., Schmitt, F. C., Ashworth, A., Reis-Filho, J. S. (2007) Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: A morphologic, ultrastructural, immunohistochemical, and in situ hybridization analysis. CLINICAL CANCER RESEARCH, 13 (1). pp. 90-101. ISSN 1078-0432

Wienke, D., Davies, G. C., Johnson, D. A., Sturge, J., Lambros, M. B. K., Savage, K., Elsheikh, S. E., Green, A. R., Ellis, I. O., Robertson, D., Reis-Filho, J. S., Isacke, C. M. (2007) The collagen receptor endo180 (CD280) is expressed on basal-like breast tumor cells and promotes tumor growth in vivo. CANCER RESEARCH, 67 (21). pp. 10230-10240. ISSN 0008-5472

Amary, M. F. C., Berisha, F., Bernardi, F. D., Herbert, A., James, M., Reis-Filho, J. S., Fisher, C., Nicholson, A. G., Tirabosco, R., Diss, T. C., Flanagan, A. M. (2007) Detection of SS18-SSX fusion transcripts in formalin-fixed paraffin-embedded neoplasms: analysis of conventional RT-PCR, qRT-PCR and dual color FISH as diagnostic tools for synovial sarcoma. MODERN PATHOLOGY, 20 (4). pp. 482-496. ISSN 0893-3952

Arriola, E., Lambros, M. B. K., Jones, C., Dexter, T., Mackay, A., Tan, D. S. P., Tamber, N., Fenwick, K., Ashworth, A., Dowsett, M., Reis-Filho, J. S. (2007) Evaluation of Phi29-based whole-genome amplification for microarray-based comparative genomic hybridisation. LABORATORY INVESTIGATION, 87 (1). pp. 75-83. ISSN 0023-6837

Lee, A. H. S., Paish, E. C., Marchio, C., Sapino, A., Schmitt, F. C., Ellis, I. O., Reis-Filho, J. S. (2007) The expression of Wilms' tumour-1 and Ca125 in invasive micropapillary carcinoma of the breast. HISTOPATHOLOGY, 51 (6). pp. 824-828. ISSN 0309-0167

Elsheikh, S. E., Green, A. R., Lambros, M. B. K., Turner, N. C., Grainge, M. J., Powe, D., Ellis, I. O., Reis-Filho, J. S. (2007) FGFR1 amplification in breast carcinomas: a chromogenic in situ hybridisation analysis. BREAST CANCER RESEARCH, 9 (2). R23-R23. ISSN 1465-5411

Abdel-Fatah, T. M. A., Powe, D. G., Hodi, Z., Lee, A. H. S., Reis-Filho, J. S., Ellis, I. O. (2007) High frequency of coexistence of columnar cell lesions, lobular neoplasia, and low grade ductal carcinoma in situ with invasive tubular carcinoma and invasive lobular carcinoma. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 31 (3). pp. 417-426. ISSN 0147-5185

Westbury, C. B., Pearson, A., Nerurkar, A., Reis-Filho, J. S., Steele, D., Peckitt, C., Sharp, G., Yarnold, J. R. (2007) Hypoxia can be detected in irradiated normal human tissue: a study using the hypoxic marker pimonidazole hydrochloride. BRITISH JOURNAL OF RADIOLOGY, 80 (959). pp. 934-938. ISSN 0007-1285

Esseghir, S., Kennedy, A., Seedhar, P., Nerurkar, A., Poulsom, R., Reis-Filho, J. S., Isacke, C. M. (2007) Identification of NTN4, TRA1, and STC2 as prognostic markers in breast cancer in a screen for signal sequence encoding proteins. CLINICAL CANCER RESEARCH, 13 (11). pp. 3164-3173. ISSN 1078-0432

Pierga, J. Y., Reis-Filho, J. S., Cleator, S. J., Dexter, T., MacKay, A., Simpson, P., Fenwick, K., Iravani, M., Salter, J., Hills, M., Jones, C., Ashworth, A., Smith, I. E., Powles, T., Dowsett, M. (2007) Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapy. BRITISH JOURNAL OF CANCER, 96 (2). pp. 341-351. ISSN 0007-0920

Gomes, A. L., Reis-Filho, J. S., Lopes, J. M., Martinho, O., Lambros, M. B. K., Martins, A., Schmitt, F., Pardal, F., Reis, R. M. (2007) Molecular alterations of KIT oncogene in gliomas. CELLULAR ONCOLOGY, 29 (5). pp. 399-408. ISSN 1570-5870

McCarthy, A., Savage, K., Gabriel, A., Naceur, C., Reis-Filho, J. S., Ashworth, A. (2007) A mouse model of basal-like breast carcinoma with metaplastic elements. JOURNAL OF PATHOLOGY, 211 (4). pp. 389-398. ISSN 0022-3417

Little, S. E., Bax, D. A., Rodriguez-Pinilla, M., Natrajan, R., Messahel, B., Pritchard-Jones, K., Vujanic, G. M., Reis-Filho, J. S., Jones, C. (2007) Multifaceted Dysregulation of the Epidermal Growth Factor Receptor Pathway in Clear Cell Sarcoma of the Kidney. CLINICAL CANCER RESEARCH, 13 (15 Part 1). pp. 4360-4364. ISSN 1078-0432

Rodriguez-Pinilla, S. M., Jones, R. L., Lambros, M. B. K., Arriola, E., Savage, K., James, M., Pinder, S. E., Reis-Filho, J. S. (2007) MYC amplification in breast cancer: a chromogenic in situ hybridisation study. JOURNAL OF CLINICAL PATHOLOGY, 60 (9). pp. 1017-1023. ISSN 0021-9746

Pinder, S. E., Reis-Filho, J. S. (2007) Non-operative breast pathology: columnar cell lesions. JOURNAL OF CLINICAL PATHOLOGY, 60 (12). pp. 1307-1312. ISSN 0021-9746

Reis-Filho, J. S., Pinder, S. E. (2007) Non-operative breast pathology: lobular neoplasia. JOURNAL OF CLINICAL PATHOLOGY, 60 (12). pp. 1321-1327. ISSN 0021-9746

Di Palma, S., Lambros, M. B. K., Savage, K., Jones, C., Mackay, A., Dexter, T., Iravani, M., Fenwick, K., Ashworth, A., Reis-Filho, J. S. (2007) Oncocytic change in pleomorphic adenoma: molecular evidence in support of an origin in neoplastic cells. JOURNAL OF CLINICAL PATHOLOGY, 60 (5). pp. 492-499. ISSN 0021-9746

Esseghir, S., Todd, S. K., Hunt, T., Poulsom, R., Plaza-Menacho, I., Reis-Filho, J. S., Isacke, C. M. (2007) A role for glial cell-derived neurotrophic factor-induced expression by inflammatory cytokines and RET/GFR alpha 1 receptor up-regulation in breast cancer. CANCER RESEARCH, 67 (24). pp. 11732-11741. ISSN 0008-5472

Rodriguez-Pinilla, S. M., Sarrio, D., Moreno-Bueno, G., Rodriguez-Gil, Y., Martinez, M. A., Hernandez, L., Hardisson, D., Reis-Filho, J. S., Palacios, J. (2007) Sox2: a possible driver of the basal-like phenotype in sporadic breast cancer. MODERN PATHOLOGY, 20 (4). pp. 474-481. ISSN 0893-3952

Arriola, E., Rodriguez-Pinilla, S. M., Lambros, M. B. K., Jones, R. L., James, M., Savage, K., Smith, I. E., Dowsett, M., Reis-Filho, J. S. (2007) Topoisomerase II alpha amplification may predict benefit from adjuvant anthracyclines in HER2 positive early breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 106 (2). pp. 181-189. ISSN 0167-6806

Mansson, S. S., Reis-Filho, J., Landberg, G. (2007) Transcriptional upregulation and unmethylation of the promoter region of p16 in invasive basal cell carcinoma cells and partial co-localization with the gamma 2 chain of laminin-332. JOURNAL OF PATHOLOGY, 212 (1). pp. 102-111. ISSN 0022-3417

Natrajan, R., Little, S. E., Reis-Filho, J. S., Hing, L., Messahel, B., Grundy, P. E., Dome, J. S., Schneider, T., Vujanic, G. M., Pritchard-Jones, K., Jones, C. (2006) Amplification and overexpression of CACNA1E correlates with relapse in favorable histology Wilms' tumors. CLINICAL CANCER RESEARCH, 12 (24). pp. 7284-7293. ISSN 1078-0432

Natrajan, R., Williams, R. D., Hing, S. N., Mackay, A., Reis-Filho, J. S., Fenwick, K., Iravani, M., Valgeirsson, H., Grigoriadis, A., Langford, C. F., Dovey, O., Gregory, S. G., Weber, B. L., Ashworth, A., Grundy, P. E., Pritchard-Jones, K., Jones, C. (2006) Array CGH profiling of favourable histology Wilms tumours reveals novel gains and losses associated with relapse. JOURNAL OF PATHOLOGY, 210 (1). pp. 49-58. ISSN 0022-3417

Little, S. E., Vuononvirta, R., Reis-Filho, J. S., Natrajan, R., Iravani, M., Fenwick, K., Mackay, A., Ashworth, A., Pritchard-Jones, K., Jones, C. (2006) Array CGH using whole genome amplification of fresh-frozen and formalin-fixed, paraffin-embedded tumor DNA. GENOMICS, 87 (2). pp. 298-306. ISSN 0888-7543

Banerjee, S., Reis-Filho, J. S., Ashley, S., Steele, D., Ashworth, A., Lakhani, S. R., Smith, I. E. (2006) Basal-like breast carcinomas: clinical outcome and response to chemotherapy. JOURNAL OF CLINICAL PATHOLOGY, 59 (7). pp. 729-735. ISSN 0021-9746

Natrajan, R., Reis-Filho, J. S., Little, S. E., Messahel, B., Brundler, M. A., Dome, J. S., Grundy, P. E., Vujanic, G. M., Pritchard-Jones, K., Jones, C. (2006) Blastemal expression of type I insulin-like growth factor receptor in Wilms' tumors is driven by increased copy number and correlates with relapse. CANCER RESEARCH, 66 (23). pp. 11148-11155. ISSN 0008-5472

Reis-Filho, J. S., Savage, K., Lambros, M. B. K., James, M., Steele, D., Jones, R. L., Dowsett, M. (2006) Cyclin D1 protein overexpression and CCND1 amplification in breast carcinomas: an immunohistochemical and chromogenic in situ hybridisation analysis. MODERN PATHOLOGY, 19 (7). pp. 999-1009. ISSN 0893-3952

Reis-Filho, J. S., Steele, D., Di Palma, S., Jones, R. L., Savage, K., James, M., Milanezi, F., Schmitt, F. C., Ashworth, A. (2006) Distribution and significance of nerve growth factor receptor (NGFR/p75(NTR)) in normal, benign and malignant breast tissue. MODERN PATHOLOGY, 19 (2). pp. 307-319. ISSN 0893-3952

Reis-Filho, J. S., Pinheiro, C., Lambros, M. B. K., Milanezi, F., Carvalho, S., Savage, K., Simpson, P. T., Jones, C., Swift, S., Mackay, A., Reis, R. M., Hornick, J. L., Pereira, E. M., Baltazar, F., Fletcher, C. D. M., Ashworth, A., Lakhani, S. R., Schmitt, F. C. (2006) EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. JOURNAL OF PATHOLOGY, 209 (4). pp. 445-453. ISSN 0022-3417

Grigoriadis, A., Mackay, A., Reis-Filho, J. S., Steele, D., Iseli, C., Stevenson, B. J., Jongeneel, C. V., Valgeirsson, H., Fenwick, K., Iravani, M., Leao, M., Simpson, A. J. G., Strausberg, R. L., Jat, P. S., Ashworth, A., Neville, A. M., O'Hare, M. J. (2006) Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data. BREAST CANCER RESEARCH, 8 (5). ISSN 1465-5411

Reis-Filho, J. S., Simpson, P. T., Turner, N. C., Lambros, M. B., Jones, C., Mackay, A., Grigoriadis, A., Sarrio, D., Savage, K., Dexter, T., Iravani, M., Fenwick, K., Weber, B., Hardisson, D., Schmitt, F. C., Palacios, J., Lakhani, S. R., Ashworth, A. (2006) FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas. CLINICAL CANCER RESEARCH, 12 (22). pp. 6652-6662. ISSN 1078-0432

Esseghir, S., Reis-Filho, J. S., Kennedy, A., James, M., O'Hare, M. J., Jeffery, R., Poulsom, R., Isacke, C. M. (2006) Identification of transmembrane proteins as potential prognostic markers and therapeutic targets in breast cancer by a screen for signal sequence encoding transcripts. JOURNAL OF PATHOLOGY, 210 (4). pp. 420-430. ISSN 0022-3417

Reis-Filho, J. S., Milanezi, F., Steele, D., Savage, K., Simpson, P. T., Nesland, J. M., Pereira, E. M., Lakhani, S. R., Schmitt, F. C. (2006) Metaplastic breast carcinomas are basal-like tumours. HISTOPATHOLOGY, 49 (1). pp. 10-21. ISSN 0309-0167

Fulford, L. G., Easton, D. F., Reis-Filho, J. S., Sofronis, A., Gillett, C. E., Lakhani, S. R., Hanby, A. (2006) Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast. HISTOPATHOLOGY, 49 (1). pp. 22-34. ISSN 0309-0167

Lambros, M. B. K., Simpson, P. T., Jones, C., Natrajan, R., Westbury, C., Steele, D., Savage, K., Mackay, A., Schmitt, F. C., Ashworth, A., Reis-Filho, J. S. (2006) Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridization. LABORATORY INVESTIGATION, 86 (4). pp. 398-408. ISSN 0023-6837

Simpson PT, Gale T, Reis-Filho JS, Jones C, Parry S, Sloane JP, Hanby A, Pinder SE, Lee AHS, Humphreys S, Ellis IO, Lakhani SR (2005) Columnar cell lesions of the breast: The missing link in breast cancer progression? A morphological and molecular analysis. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 29 (6). pp. 734-746. ISSN 0147-5185

Reis, R. M., Reis-Filho, J. S., Longatto, A., Tomarev, S., Silva, P., Lopes, J. M. (2005) Differential Prox-1 and CD 31 expression in mucousae, cutaneous and soft tissue vascular lesions and tumors. PATHOLOGY, RESEARCH AND PRACTICE, 201 (12). pp. 771-776. ISSN 0344-0338

Reis-Filho, J. S., Schmitt, F. C. D. (2005) Fluorescence in situ hybridization, comparative genomic hybridization, and other molecular biology techniques in the analysis of effusions. DIAGNOSTIC CYTOPATHOLOGY, 33 (5). pp. 294-299. ISSN 8755-1039

Reis-Filho, J. S., Milanezi, F., Carvalho, S., Simpson, P. T., Steele, D., Savage, K., Lambros, M. B. K., Pereira, E. M., Nesland, J. M., Lakhani, S. R., Schmitt, F. C. (2005) Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis. BREAST CANCER RESEARCH, 7 (6). R1028-R1035. ISSN 1465-5411

Reis-Filho JS, Simpson PT, Jones C, Steele D, Mackay A, Iravani M, Fenwick K, Valgeirsson H, Lambros M, Ashworth A, Palacios J, Schmitt F, Lakhani SR (2005) Pleomorphic lobular carcinoma of the breast: role of comprehensive molecular pathology in characterization of an entity. JOURNAL OF PATHOLOGY, 207 (1). pp. 1-13. ISSN 0022-3417

Lakhani, S. R., Reis-Filho, J. S,. Fulford, L., Penault-Llorca, F., van der Vjiver, M., Parry, S., Bishop, T., Benitez, J., Rivas, C., Bignon, Y. J,. Chang-Claude, J., Hamann, U., Cornelisse, C. J., Devilee, P., Beckmann, M. W., Nestle-Kramling, C., Daly, P. A., Haites, N., Varley, J., Lalloo, F., Evans, G., Maugard, C., Meijers-Heijboer, H., Klijn, J. G. M., Olah, E., Gusterson, B. A., Pilotti, S., Radice, P., Scherneck, S., Sobol, H., Jacquemier, J., Wagner, T., Peto, J., Stratton, M. R., McGuffog, L., Easton, D. F. (2005) Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype. CLINICAL CANCER RESEARCH, 11 (14). pp. 5175-5180. ISSN 1078-0432

Reis-Filho, J. S., Fulford, L. G., Crebassa, B., Carpentier, S., Lakhani, S. R. (2004) Collagenous spherulosis in an adenomyoepithelioma of the breast. JOURNAL OF CLINICAL PATHOLOGY, 57 (1). pp. 83-86. ISSN 0021-9746

Clarke CL, Sandle J, Parry SC, Reis-Filho JS, O'Hare MJ, Lakhani SR (2004) Cytokeratin 5/6 in normal human breast: lack of evidence for a stem cell phenotype. JOURNAL OF PATHOLOGY, 204 (2). pp. 147-152. ISSN 0022-3417

Simpson PT, Gale T, Reis-Filho JS, Jones C, Parry S, Steele D, Cossu A, Budroni M, Palmieri G, Lakhani SR (2004) Distribution and significance of 14-3-3 sigma, a novel myoepithelial marker, in normal, benign, and malignant breast tissue. JOURNAL OF PATHOLOGY, 202 (3). pp. 274-285. ISSN 0022-3417

Angele, S., Jones, C., Reis-Filho, J. S., Fulford, L. G., Treilleux, I., Lakhani, S. R., Hall, J. (2004) Expression of ATM, p53, and the MRE11-Rad50-NBS1 complex in myoepithelial cells from benign and malignant proliferations of the breast. JOURNAL OF CLINICAL PATHOLOGY, 57 (11). pp. 1179-1184. ISSN 0021-9746

Jones, C., Mackay, A., Grigoriadis, A., Cossu, A., Reis-Filho, J. S., Fulford, L., Dexter, T., Davies, S., Bulmer, K., Ford, E., Parry, S., Budroni, M., Palmieri, G., Neville, A. M., O'Hare, M. J., Lakhani, S. R. (2004) Expression profiling of purified normal human luminal and myoepithelial breast cells: Identification of novel prognostic markers for breast cancer. CANCER RESEARCH, 64 (9). pp. 3037-3045. ISSN 0008-5472

Cruz, J., Reis-Filho, J. S., Lopes, J. M. (2004) Malignant peripheral nerve sheath tumour-like primary cutaneous malignant melanoma. JOURNAL OF CLINICAL PATHOLOGY, 57 (2). pp. 218-220. ISSN 0021-9746

Jones, C., Ford, E., Gillett, C., Ryder, K., Merrett, S., Reis-Filho, J. S., Fulford, L. G., Hanby, A., Lakhani, S. R. (2004) Molecular cytogenetic identification of subgroups of grade III invasive ductal breast carcinomas with different clinical outcomes. CLINICAL CANCER RESEARCH, 10 (18). pp. 5988-5997. ISSN 1078-0432

Reis-Filho JS, Simpson PT, Fulford LG, Martins A, Schmitt FC (2004) p63-driven nuclear accumulation of beta-catenin is not a frequent event in human neoplasms. PATHOLOGY, RESEARCH AND PRACTICE, 199 (12). pp. 785-793. ISSN 0344-0338

Preto, A., Cameselle-Teijeiro, J., Moldes-Boullosa, J., Soares, P., Cameselle-Teijeiro, J. F., Silva, P., Reis-Filho, J. S., Reyes-Santias, R. M., Alfonsin-Barreiro, N., Forteza, J., Sobrinho-Simoes, M. (2004) Telomerase expression and proliferative activity suggest a stem cell role for thyroid solid cell nests. MODERN PATHOLOGY, 17 (7). pp. 819-826. ISSN 0893-3952

Reis-Filho JS, Simpson PT, Martins A, Preto A, Gartner F, Schmitt FC (2003) Distribution of p63, cytokeratins 5/6 and cytokeratin 14 in 51 normal and 400 neoplastic human tissue samples using TARP-4 multi-tumor tissue microarray. VIRCHOWS ARCHIV, 443 (2). pp. 122-132. ISSN 0945-6317

Reis-Filho JS, Fulford LG, Freeman A, Lakhani SR (2003) Pathologic quiz case - A 93-year-old woman with an enlarged and tender left breast. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 127 (12). pp. 1626-1628. ISSN 0003-9985

Book Section

Simpson, P. T., Reis-Filho, J. S., Lakhani, S. R. (2009) Lobular Carcinoma In Situ: Biology and Pathology. In: Diseases of the Breast (4th ed.). Lippincott Williams and Wilkins, Philadelphia, USA, pp. 333-340. ISBN 978-078179117-5

Editorial

Moelans, C. B., Reis, J. S., van Diest, P. J. (2011) Implications of rarity of chromosome 17 polysomy in breast cancer. LANCET ONCOLOGY, 12 (12). pp. 1087-1089. ISSN 1470-2045

Lacroix-Triki, M., Geyer, F. C., Reis-Filho, J. S. (2010) Caveolin-1 P132L Mutation in Human Cancers 1 CAVeat to be Voiced. JOURNAL OF MOLECULAR DIAGNOSTICS, 12 (5). pp. 562-565. ISSN 1525-1578

Weigelt, B., Mackay, A., Natrajan, R., Tan, D. S. P., Dowsett, M., Ashworth, A., Reis-Filho, J. S. (2010) The importance of gene-centring microarray data Reply. LANCET ONCOLOGY, 11 (8). pp. 720-721. ISSN 1470-2045

Hall, P. A., Reis-Filho, J. S., Tomlinson, I. P. M., Poulsom, R. (2010) An introduction to genes, genomes and disease. JOURNAL OF PATHOLOGY, 220 (2). pp. 109-113. ISSN 0022-3417

Weigelt, B., Reis-Filho, J. S. (2010) Molecular profiling currently offers no more than tumour morphology and basic immunohistochemistry INTRODUCTION. BREAST CANCER RESEARCH, 12 (Suppl. 4). ISSN 1465-5411

Smalley, M. J., Reis-Filho, J. S., Ashworth, A. (2008) BRCa1 and stem cells: tumour typecasting. NATURE CELL BIOLOGY, 10 (4). pp. 377-379. ISSN 1465-7392

Reis-Filho, J. S., Lakhani, S. R. (2008) Breast cancer special types: why bother? JOURNAL OF PATHOLOGY, 216 (4). pp. 394-398. ISSN 0022-3417

Tan, D. S. P., Lambros, M. B. K., Marchio, C., Reis-Filho, J. S. (2008) ESR1 amplification in endometrial carcinomas: hope or hyperbole? JOURNAL OF PATHOLOGY, 216 (3). pp. 271-274. ISSN 0022-3417

Kilburn, L. S., T.N.T. Trial Management Group, [Group Author] (2008) 'Triple negative' breast cancer: a new area for phase III breast cancer clinical trials. CLINICAL ONCOLOGY, 20 (1). pp. 35-39. ISSN 0936-6555

Pinder, S. E., Reis-Filho, J. S. (2007) Non-operative breast pathology. JOURNAL OF CLINICAL PATHOLOGY, 60 (12). pp. 1297-1299. ISSN 0021-9746

Letter

Rakha, E., Ellis, I., Reis-Filho, J. (2008) Are triple-negative and basal-like breast cancer synonymous? CLINICAL CANCER RESEARCH, 14 (2). p. 618. ISSN 1078-0432

Reis-Filho, J. S., Drury, S., Lambros, M. B., Marchio, C., Johnson, N., Natrajan, R., Salter, J., Levey, P., Fletcher, O., Peto, J., Ashworth, A., Dowsett, M. (2008) ESR1 gene amplification in breast cancer: a common phenomenon? NATURE GENETICS, 40 (7). pp. 809-810. ISSN 1061-4036

Rakha, E. A., Ellis, I. O., Reis-Filho, J. S. (2008) Immunohistochemical heterogeneity of breast carcinomas negative for estrogen receptors, progesterone receptors and Her2/neu (basal-like breast carcinomas). MODERN PATHOLOGY, 21 (8). pp. 1060-1061. ISSN 0893-3952

Rakha, E. A., Tan, D. S. P., Foulkes, W. D., Ellis, I. O., Tutt, A., Nielsen, T. O., Reis-Filho, J. S. (2007) Are triple-negative tumours and basal-like breast cancer synonymous? BREAST CANCER RESEARCH, 9 (6). ISSN 1465-5411

Pierga, J. Y., Reis-Filho, J. S. (2005) Ewing's sarcoma of the rectum: Can we afford not to use molecular pathology? JOURNAL OF CLINICAL ONCOLOGY, 23 (30). pp. 7761-7762. ISSN 0732-183X

Reis-Filho JS (2005) Re: Korsching et al. The origin of vimentin expression in invasive breast cancer: epithelial-mesenchymal transition, myoepithelial histogenesis or histogenesis from progenitor cells with bilinear differentiation potential? J Pathol 2005; 206: 451-457. JOURNAL OF PATHOLOGY, 207 (3). pp. 367-369. ISSN 0022-3417

Reis-Filho JS (2003) Primary salivary clear cell tumors. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 127 (3). pp. 278-279. ISSN 0003-9985

Reis-Filho JS (2003) Re: Sastre-Garau et al. Inflammatory myofibroblastic tumour (inflammatory pseudotumour) of the breast: clinicopathological and genetic analysis of a case with evidence for clonality. J Pathol 2002; 196 : 97-102. JOURNAL OF PATHOLOGY, 200 (2). pp. 269-271. ISSN 0022-3417

Review Article

Geyer, F. C., Rodrigues, D. N., Weigelt, B., Reis, J. S. (2012) Molecular Classification of Estrogen Receptor-positive/Luminal Breast Cancers. ADVANCES IN ANATOMIC PATHOLOGY, 19 (1). pp. 39-53. ISSN 1072-4109

Badve, S., Dabbs, D. J., Schnitt, S. J., Baehner, F. L., Decker, T., Eusebi, V., Fox, S. B., Ichihara, S., Jacquemier, J., Lakhani, S. R., Palacios, J., Rakha, E. A., Richardson, A. L., Schmitt, F. C., Tan, P., Tse, G. M., Weigelt, B., Ellis, I. O., Reis-Filho, J. S. (2011) Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists. MODERN PATHOLOGY, 24 (2). pp. 157-167. ISSN 0893-3952

Andre, F., McShane, L. M., Michiels, S., Ransohoff, D. F., Altman, D. G., Reis, J. S., Hayes, D. F., Pusztai, L. (2011) Biomarker studies: a call for a comprehensive biomarker study registry. NATURE REVIEWS CLINICAL ONCOLOGY, 8 (3). pp. 171-176. ISSN 1759-4774

Dedes, K. J., Wetterskog, D., Ashworth, A., Kaye, S. B., Reis, J. S. (2011) Emerging therapeutic targets in endometrial cancer. NATURE REVIEWS CLINICAL ONCOLOGY, 8 (5). pp. 261-271. ISSN 1759-4774

Colombo, P. E., Milanezi, F., Weigelt, B., Reis, J. S. (2011) Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and prediction. BREAST CANCER RESEARCH, 13 (3). ISSN 1465-5411

Natrajan, R., Reis, J. S. (2011) Next-generation sequencing applied to molecular diagnostics. EXPERT REVIEW OF MOLECULAR DIAGNOSTICS, 11 (4). pp. 425-444. ISSN 1473-7159

Marchio, C., Dowsett, M., Reis, J. S. (2011) Revisiting the technical validation of tumour biomarker assays: how to open a Pandora's box. BMC MEDICINE, 9 . ISSN 1741-7015

Marchio, C., Weigelt, B., Reis-Filho, J. S. (2010) Adenoid cystic carcinomas of the breast and salivary glands (or 'The strange case of Dr Jekyll and Mr Hyde' of exocrine gland carcinomas). JOURNAL OF CLINICAL PATHOLOGY, 63 (3). pp. 220-228. ISSN 0021-9746

Lopez-Garcia, M. A., Geyer, F. C., Lacroix-Triki, M., Marchio, C., Reis-Filho, J. S. (2010) Breast cancer precursors revisited: molecular features and progression pathways. HISTOPATHOLOGY, 57 (2). pp. 171-192. ISSN 0309-0167

Rakha, E. A., Reis-Filho, J. S., Baehner, F., Dabbs, D. J., Decker, T., Eusebi, V., Fox, S. B., Ichihara, S., Jacquemier, J., Lakhani, S. R., Palacios, J., Richardson, A. L., Schnitt, S. J., Schmitt, F. C., Tan, P., Tse, G. M., Badve, S., Ellis, I. O. (2010) Breast cancer prognostic classification in the molecular era: the role of histological grade. BREAST CANCER RESEARCH, 12 (4). ISSN 1465-5411

Rakha, E. A., Reis-Filho, J. S., Ellis, I. O. (2010) Combinatorial biomarker expression in breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 120 (2). pp. 293-308. ISSN 0167-6806

Weigelt, B., Baehner, F. L., Reis-Filho, J. S. (2010) The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade. JOURNAL OF PATHOLOGY, 220 (2). pp. 263-280. ISSN 0022-3417

Shiu, K., Natrajan, R., Geyer, F. C., Ashworth, A., Reis-Filho, J. S. (2010) DNA amplifications in breast cancer: genotypic-phenotypic correlations. FUTURE ONCOLOGY, 6 (6). pp. 967-984. ISSN 1479-6694

Weigelt, B., Geyer, F. C., Reis-Filho, J. S. (2010) Histological types of breast cancer: How special are they? MOLECULAR ONCOLOGY, 4 (3). pp. 192-208. ISSN 1574-7891

Foulkes, W. D., Smith, I. E., Reis-Filho, J. S. (2010) Triple-Negative Breast Cancer. NEW ENGLAND JOURNAL OF MEDICINE, 363 (20). pp. 1938-1948. ISSN 0028-4793

Rakha, E., Reis-Filho, J. S. (2009) Basal-like Breast Carcinoma From Expression Profiling to Routine Practice. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 133 (6). pp. 860-868. ISSN 0003-9985

Geyer, F. C., Lopez-Garcia, M. A., Lambros, M. B., Reis-Filho, J. S. (2009) Genetic characterization of breast cancer and implications for clinical management. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 13 (10). pp. 4090-4103. ISSN 1582-1838

Weigelt, B., Reis-Filho, J. S. (2009) Histological and molecular types of breast cancer: is there a unifying taxonomy? NATURE REVIEWS CLINICAL ONCOLOGY, 6 (12). pp. 718-730. ISSN 1759-4774

Geyer, F. C., Reis-Filho, J. S. (2009) Microarray-based Gene Expression Profiling as a Clinical Tool for Breast Cancer Management: Are We There Yet? INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY, 17 (4). pp. 285-302. ISSN 1066-8969

Rakha, E. A., El-Sayed, M. E., Reis-Filho, J., Ellis, I. O. (2009) Patho-biological aspects of basal-like breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 113 (3). pp. 411-422. ISSN 0167-6806

Geyer, F. C., Marchio, C., Reis-Filho, J. S. (2009) The role of molecular analysis in breast cancer. PATHOLOGY, 41 (1). pp. 77-88. ISSN 0031-3025

Rakha, E. A., Reis-Filho, J. S., Ellis, I. O. (2008) Basal-like breast cancer: A critical review. JOURNAL OF CLINICAL ONCOLOGY, 26 (15). pp. 2568-2581. ISSN 0732-183X

Tan, D. S. R., Reis-Filho, J. S. (2008) Comparative genomic hybridisation arrays: High-throughput tools to determine targeted therapy in breast cancer. PATHOBIOLOGY, 75 (2). pp. 63-74. ISSN 1015-2008

Shiu, K. K., Tan, D. S. P., Reis-Filho, J. S. (2008) Development of therapeutic approaches to 'triple negative' phenotype breast cancer. EXPERT OPINION ON THERAPEUTIC TARGETS, 12 (9). pp. 1123-1137. ISSN 1472-8222

Rakha, E. A., El-Sayed, M. E., Reis-Filho, J. S., Ellis, I. O. (2008) Expression profiling technology: its contribution to our understanding of breast cancer. HISTOPATHOLOGY, 52 (1). pp. 67-81. ISSN 0309-0167

Tan, D. S. P., Marchio, C., Reis-Filho, J. S. (2008) Hereditary breast cancer: from molecular pathology to tailored therapies. JOURNAL OF CLINICAL PATHOLOGY, 61 (10). pp. 1073-1082. ISSN 0021-9746

Rakha, E. A., Reis-Filho, J. S., Ellis, I. O. (2008) Impact of basal-like breast carcinoma determination for a more specific therapy. PATHOBIOLOGY, 75 (2). pp. 95-103. ISSN 1015-2008

Reis-Filho, J. S., Tutt, A. N. J. (2008) Triple negative tumours: a critical review. HISTOPATHOLOGY, 52 (1). pp. 108-118. ISSN 0309-0167

Lambros, M. B. K., Natrajan, R., Reis-Filho, J. S. (2007) Chromogenic and fluorescent in situ hybridization in breast cancer. HUMAN PATHOLOGY, 38 (8). pp. 1105-1122. ISSN 0046-8177

Tan, D. S. P., Lambros, M. B. K., Natrajan, R., Reis-Filho, J. S. (2007) Getting it right: designing microarray (and not 'microawry') comparative genomic hybridization studies for cancer research. LABORATORY INVESTIGATION, 87 (8). pp. 737-754. ISSN 0023-6837

Pinder, S. E., Provenzano, E., Reis-Filho, J. S. (2007) Lobular in situ neoplasia and columnar cell lesions: diagnosis in breast core biopsies and implications for management. PATHOLOGY, 39 (2). pp. 208-216. ISSN 0031-3025

Turner, N. C., Reis-Filho, J. S. (2006) Basal-like breast cancer and the BRCA1 phenotype. ONCOGENE, 25 (43). pp. 5846-5853. ISSN 0950-9232

Reis-Filho, J. S., Westbury, C., Pierga, J. Y. (2006) The impact of expression profiling on prognostic and predictive testing in breast cancer. JOURNAL OF CLINICAL PATHOLOGY, 59 (3). pp. 225-231. ISSN 0021-9746

Simpson PT, Reis-Filho JS, Gale T, Lakhani SR (2005) Molecular evolution of breast cancer. JOURNAL OF PATHOLOGY, 205 (2). pp. 248-254. ISSN 0022-3417

Reis-Filho JS, Simpson PT, Gale T, Lakhani SR (2005) The molecular genetics of breast cancer: The contribution of comparative genomic hybridization. PATHOLOGY, RESEARCH AND PRACTICE, 201 (11). pp. 713-725. ISSN 0344-0338

Schmitt, F. C,. Reis-Filho, J. S. (2003) c-myc, not her-2/neu, can predict the prognosis of breast cancer patients: how novel, how accurate, and how significant? BREAST CANCER RESEARCH, 5 (4). pp. 188-191. ISSN 1465-5411

Reis-Filho, J. S., Lakhani, S. R. (2003) The diagnosis and management of pre-invasive breast disease - Genetic alterations in pre-invasive lesions. BREAST CANCER RESEARCH, 5 (6). pp. 313-319. ISSN 1465-5411

Simpson, P. T., Gale, T., Fulford, L. G., Reis-Filho, J. S., Lakhani, S. R. (2003) The diagnosis and management of pre-invasive breast disease - Pathology of atypical lobular hyperplasia and lobular carcinoma in situ. BREAST CANCER RESEARCH, 5 (5). pp. 258-262. ISSN 1465-5411

Pia-Foschini, M., Reis-Filho, J. S., Eusebi, V., Lakhani, S. R. (2003) Salivary gland-like tumours of the breast: surgical and molecular pathology. JOURNAL OF CLINICAL PATHOLOGY, 56 (7). pp. 497-506. ISSN 0021-9746