Article

Curry, E., Zeller, C., Masrour, N., Patten, D. K., Gallon, J., Wilhelm-Benartzi, C. S., Ghaem-Maghami, S., Bowtell, D. D., Brown, R. (2018) Genes Predisposed to DNA Hypermethylation during Acquired Resistance to Chemotherapy Are Identified in Ovarian Tumors by Bivalent Chromatin Domains at Initial Diagnosis. CANCER RESEARCH, 78 (6). pp. 1383-1391. ISSN 0008-5472

Flanagan, J. M., Wilson, A., Koo, C., Masrour, N., Gallon, J., Loomis, E., Flower, K., Wilhelm-Benartzi, C., Hergovich, A., Cunnea, P., Gabra, H., Braicu, E. I., Sehouli, J., Darb-Esfahani, S., Vanderstichele, A., Vergote, I., Kreuzinger, C., Castillo-Tong, D. C., Wisman, G. B. A., Berns, E. M., Siddiqui, N., Paul, J., Brown, R. (2017) Platinum-Based Chemotherapy Induces Methylation Changes in Blood DNA Associated with Overall Survival in Patients with Ovarian Cancer. CLINICAL CANCER RESEARCH, 23 (9). pp. 2213-2222. ISSN 1078-0432

Bonito, N. A., Borley, J., Wilhelm-Benartzi, C. S., Ghaem-Maghami, S., Brown, R. (2016) Epigenetic Regulation of the Homeobox Gene MSX1 Associates with Platinum-Resistant Disease in High-Grade Serous Epithelial Ovarian Cancer. CLINICAL CANCER RESEARCH, 22 (12). pp. 3097-3104. ISSN 1078-0432

Flower, K. J., Shenker, N. S., El-Bahrawy, M., Goldgar, D. E., Parsons, M. T., Spurdle, A. B., Morris, J. R., Brown, R., Flanagan, J. M., Investigators, K. ConFab, Affect Study, Grp (2015) DNA methylation profiling to assess pathogenicity of BRCA1 unclassified variants in breast cancer. Epigenetics, 10 (12). pp. 1121-1132. ISSN 1559-2294

Curry, E., Green, I., Chapman-Rothe, N., Shamsaei, E., Kandil, S., Cherblanc, F. L., Payne, L., Bell, E., Ganesh, T., Srimongkolpithak, N., Caron, J., Li, F. L., Uren, A. G., Snyder, J. P., Vedadi, M., Fuchter, M. J., Brown, R. (2015) Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells. Clinical Epigenetics, 7. ISSN 1868-7083

Flanagan, J. M., Brook, M. N., Orr, N., Tomczyk, K., Coulson, P., Fletcher, O., Jones, M. E., Schoemaker, M. J., Ashworth, A., Swerdlow, A., Brown, R., Garcia-Closas, M. (2015) Temporal Stability and Determinants of White Blood Cell DNA Methylation in the Breakthrough Generations Study. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 24 (1). pp. 221-229. ISSN 1055-9965

Dai, W., Zeller, C., Masrour, N., Siddiqui, N., Paul, J., Brown, R. (2013) Promoter CpG Island Methylation of Genes in Key Cancer Pathways Associates with Clinical Outcome in High-Grade Serous Ovarian Cancer. CLINICAL CANCER RESEARCH, 19 (20). pp. 5788-5797. ISSN 1078-0432

Zeller, C., Dai, W., Steele, N. L., Siddiq, A., Walley, A. J., Wilhelm-Benartzi, C. S. M., Rizzo, S., van der Zee, A., Plumb, J. A., Brown, R. (2012) Candidate DNA methylation drivers of acquired cisplatin resistance in ovarian cancer identified by methylome and expression profiling. ONCOGENE, 31 (42). pp. 4567-4576. ISSN 0950-9232

Brennan, K., Garcia-Closas, M., Orr, N., Fletcher, O., Jones, M., Ashworth, A., Swerdlow, A., Thorne, H., Riboli, E., Vineis, P., Dorronsoro, M., Clavel-Chapelon, F., Panico, S., Onland-Moret, N. C., Trichopoulos, D., Kaaks, R., Khaw, K. T., Brown, R., Flanagan, J. M., Investigators, K. ConFab (2012) Intragenic ATM Methylation in Peripheral Blood DNA as a Biomarker of Breast Cancer Risk. CANCER RESEARCH, 72 (9). pp. 2304-2313. ISSN 0008-5472

Rizzo, S., Hersey, J. M., Mellor, P., Dai, W., Santos-Silva, A., Liber, D., Luk, L., Titley, I., Carden, C. P., Box, G., Hudson, D. L., Kaye, S. B., Brown, R. (2011) Ovarian Cancer Stem Cell-Like Side Populations Are Enriched Following Chemotherapy and Overexpress EZH2. MOLECULAR CANCER THERAPEUTICS, 10 (2). pp. 325-335. ISSN 1535-7163

Dai, W., Teodoridis, J. M., Zeller, C., Graham, J., Hersey, J., Flanagan, J. M., Stronach, E., Millan, D. W., Siddiqui, N., Paul, J., Brown, R. (2011) Systematic CpG Islands Methylation Profiling of Genes in the Wnt Pathway in Epithelial Ovarian Cancer Identifies Biomarkers of Progression-Free Survival. CLINICAL CANCER RESEARCH, 17 (12). pp. 4052-4062. ISSN 1078-0432

Steele, N. L., Plumb, J. A., Vidal, L., Tjornelund, J., Knoblauch, P., Rasmussen, A., Ooi, C. E., Buhl-Jensen, P., Brown, R., Evans, T. R. J., DeBono, J. S. (2008) A phase 1 pharmacokinetic and pharmacodynamic study of the histone deacetylase inhibitor belinostat in patients with advanced solid tumors. CLINICAL CANCER RESEARCH, 14 (3). pp. 804-810. ISSN 1078-0432

Appleton, K., Mackay, H. J., Judson, I., Plumb, J. A., McCormick, C., Strathdee, G., Lee, C., Barrett, S., Reade, S., Jadayel, D., Tang, A., Bellenger, K., Mackay, L., Setanoians, A., Schatzlein, A., Twelves, C., Kaye, S. B., Brown, R. (2007) Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors. JOURNAL OF CLINICAL ONCOLOGY, 25 (29). pp. 4603-4609. ISSN 0732-183X

Morley, S., MacDonald, G., Kirn, D., Kaye, S., Brown, R., Soutar, D. (2004) The dl1520 virus is found preferentially in tumor tissue after direct intratumoral injection in oral carcinoma. CLINICAL CANCER RESEARCH, 10 (13). pp. 4357-4362. ISSN 1078-0432

Review Article

Wilhelm-Benartzi, C. S., Koestler, D. C., Karagas, M. R., Flanagan, J. M., Christensen, B. C., Kelsey, K. T., Marsit, C. J., Houseman, E. A., Brown, R. (2013) Review of processing and analysis methods for DNA methylation array data. BRITISH JOURNAL OF CANCER, 109 (6). pp. 1394-1402. ISSN 0007-0920

Borley, J., Wilhelm-Benartzi, C., Brown, R., Ghaem-Maghami, S. (2012) Does tumour biology determine surgical success in the treatment of epithelial ovarian cancer? A systematic literature review. BRITISH JOURNAL OF CANCER, 107 (7). pp. 1069-1074. ISSN 0007-0920