Article

Dowsett, M., Cuzick, J., Ingle, J., Coates, A., Forbes, J., Bliss, J., Buyse, M., Baum, M., Buzdar, A., Colleoni, M., Coombes, C., Snowdon, C., Gnant, M., Jakesz, R., Kaufmann, M., Boccardo, F., Godwin, J., Davies, C., Peto, R. (2010) Meta-Analysis of Breast Cancer Outcomes in Adjuvant Trials of Aromatase Inhibitors Versus Tamoxifen. JOURNAL OF CLINICAL ONCOLOGY, 28 (3). pp. 509-518. ISSN 0732-183X

Freedman, O. C., Amir, E., Hanna, W., Kahn, H., O'Malley, F., Dranitsaris, G., Cole, D. E. C., Verma, S., Folkerd, E., Dowsett, M., Clemons, M. (2010) A randomized trial exploring the biomarker effects of neoadjuvant sequential treatment with exemestane and anastrozole in post-menopausal women with hormone receptor-positive breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 119 (1). pp. 155-161. ISSN 0167-6806

Jones, R. L., Salter, J., A'Hern, R., Nerurkar, A., Parton, M., Reis-Filho, J. S., Smith, I. E., Dowsett, M. (2010) Relationship between oestrogen receptor status and proliferation in predicting response and long-term outcome to neoadjuvant chemotherapy for breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 119 (2). pp. 315-323. ISSN 0167-6806

Roddam, A. W., Appleby, P., Neale, R., Dowsett, M., Folkerd, E., Tipper, S., Allen, N. E., Key, T. J. (2009) Association between endogenous plasma hormone concentrations and fracture risk in men and women: the EPIC-Oxford prospective cohort study. JOURNAL OF BONE AND MINERAL METABOLISM, 27 (4). pp. 485-493. ISSN 0914-8779

Arnedos, M., Nerurkar, A., Osin, P., A'Hern, R., Smith, I. E., Dowsett, M. (2009) Discordance between core needle biopsy (CNB) and excisional biopsy (EB) for estrogen receptor (ER), progesterone receptor (PgR) and HER2 status in early breast cancer (EBC). ANNALS OF ONCOLOGY, 20 (12). pp. 1948-1952. ISSN 0923-7534

Dowsett, M., Procter, M., McCaskill-Stevens, W., De Azambuja, E., Dafni, U., Rueschoff, J., Jordan, B., Dolci, S., Abramovitz, M., Stoss, O., Viale, G., Gelber, R. D., Piccart-Gebhart, M., Leyland-Jones, B. (2009) Disease-Free Survival According to Degree of HER2 Amplification for Patients Treated With Adjuvant Chemotherapy With or Without 1 Year of Trastuzumab: The HERA Trial. JOURNAL OF CLINICAL ONCOLOGY, 27 (18). pp. 2962-2969. ISSN 0732-183X

Stone, J., Folkerd, E., Doody, D., Schroen, C., Treloar, S. A., Giles, G. G., Pike, M. C., English, D. R., Southey, M. C., Hopper, J. L., Dowsett, M. (2009) Familial Correlations in Postmenopausal Serum Concentrations of Sex Steroid Hormones and Other Mitogens: A Twins and Sisters Study. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM, 94 (12). pp. 4793-4800. ISSN 0021-972X

Walker, K., Fletcher, O., Johnson, N., Coupland, B., McCormack, V. A., Folkerd, E., Gibson, L., Hillier, S. G., Holly, J. M., Moss, S., Dowsett, M., Peto, J., Silva, I. S. (2009) Premenopausal Mammographic Density in Relation to Cyclic Variations in Endogenous Sex Hormone Levels, Prolactin, and Insulin-like Growth Factors. CANCER RESEARCH, 69 (16). pp. 6490-6499. ISSN 0008-5472

Jones, R. L., Salter, J., A'Hern, R., Nerurkar, A., Parton, M., Reis-Filho, J. S., Smith, I. E., Dowsett, M. (2009) The prognostic significance of Ki67 before and after neoadjuvant chemotherapy in breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 116 (1). pp. 53-68. ISSN 0167-6806

Murray, J., Young, O. E., Renshaw, L., White, S., Williams, L., Evans, D. B., Thomas, J. S., Dowsett, M., Dixon, J. M. (2009) A randomised study of the effects of letrozole and anastrozole on oestrogen receptor positive breast cancers in postmenopausal women. BREAST CANCER RESEARCH AND TREATMENT, 114 (3). pp. 495-501. ISSN 0167-6806

Drury, S., Anderson, H., Dowsett, M. (2009) Selection of Reference Genes for Normalization of qRT-PCR Data Derived From FFPE Breast Tumors. DIAGNOSTIC MOLECULAR PATHOLOGY, 18 (2). pp. 103-107. ISSN 1052-9551

Attard, G., Reid, A. H. M., A'Hern, R., Parker, C., Oommen, N. B., Folkerd, E., Messiou, C., Molife, L. R., Maier, G., Thompson, E., Olmos, D., Sinha, R., Lee, G., Dowsett, M., Kaye, S. B., Dearnaley, D., Kheoh, T., Molina, A., de Bono, J. S. (2009) Selective Inhibition of CYP17 With Abiraterone Acetate Is Highly Active in the Treatment of Castration-Resistant Prostate Cancer. JOURNAL OF CLINICAL ONCOLOGY, 27 (23). pp. 3742-3748. ISSN 0732-183X

Ellis, P., Barrett-Lee, P., Johnson, L., Cameron, D., Wardley, A., O'Reilly, S., Verrill, M., Smith, I., Yarnold, J., Coleman, R., Earl, H., Canney, P., Twelves, C., Poole, C., Bloomfield, D., Hopwood, P., Johnston, S., Dowsett, M., Bartlett, J. M. S., Ellis, I., Peckitt, C., Hall, E., Bliss, J. M., TACT Trial Management Grp, [Group Author], TACT Trialists, [Group Author] (2009) Sequential docetaxel as adjuvant chemotherapy for early breast cancer (TACT): an open-label, phase III, randomised controlled trial. LANCET, 373 (9676). pp. 1681-1692. ISSN 0140-6736

McCormack, V. A., Dowsett, M., Folkerd, E., Johnson, N., Palles, C., Coupland, B., Holly, J. M., Vinnicombe, S. J., Perry, N. M., Silva, I. S. (2009) Sex steroids, growth factors and mammographic density: a cross-sectional study of UK postmenopausal Caucasian and Afro-Caribbean women. BREAST CANCER RESEARCH, 11 (3). ISSN 1465-5411

Banerjee, S., Zvelebil, M., Furet, P., Mueller-Vieira, U., Evans, D. B., Dowsett, M., Martin, L. A. (2009) The Vascular Endothelial Growth Factor Receptor Inhibitor PTK787/ZK222584 Inhibits Aromatase. CANCER RESEARCH, 69 (11). pp. 4716-4723. ISSN 0008-5472

Sanders, M. E., Dias, E. C., Xu, B. J., Mobley, J. A., Billheimer, D., Roder, H., Grigorieva, J., Dowsett, M., Arteaga, C. L., Caprioli, R. M. (2008) Differentiating proteomic biomarkers in breast cancer by laser capture microdissection and MALDI MS. JOURNAL OF PROTEOME RESEARCH, 7 (4). pp. 1500-1507. ISSN 1535-3893

Williams, N., [ATAC Trialists Group (includes Mitch Dowsett)] (2008) Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial. LANCET ONCOLOGY, 9 (1). pp. 45-53. ISSN 1470-2045

Banerjee, S., Pancholi, S., A'Hern, R., Ghazoui, Z., Smith, I. E., Dowsett, M., Martin, L. A. (2008) The effects of neoadjuvant anastrozole and tamoxifen on circulating vascular endothelial growth factor and soluble vascular endothelial growth factor receptor 1 in breast cancer. CLINICAL CANCER RESEARCH, 14 (9). pp. 2656-2663. ISSN 1078-0432

Pancholi, S., Lykkesfeldt, A. E., Hilmi, C., Banerjee, S., Leary, A., Drury, S., Johnston, S., Dowsett, M., Martin, L. A. (2008) ERBB2 influences the subcellullar localization of the estrogen receptor in tamoxifen-resistant MCF-7 cells leading to the activation of AKT and RPS6KA2. ENDOCRINE-RELATED CANCER, 15 (4). pp. 985-1002. ISSN 1351-0088

Walker, R. A., Bartlett, J. M. S., Dowsett, M., Ellis, I. O., Hanby, A. M., Jasani, B., Miller, K., Pinder, S. E. (2008) HER2 testing in the UK: further update to recommendations. JOURNAL OF CLINICAL PATHOLOGY, 61 (7). pp. 818-824. ISSN 0021-9746

Thompson, D. J., Healey, C. S., Baynes, C., Kalmyrzaev, B., Ahmed, S., Dowsett, M., Folkerd, E., Luben, R. N., Cox, D., Ballinger, D., Pharoah, P. D. P., Ponder, B. A. J., Dunning, A. M., Easton, D. F., Studies Epidemiology Risks Can, [Group Author] (2008) Identification of Common Variants in the SHBG Gene Affecting Sex Hormone-Binding Globulin Levels and Breast Cancer Risk in Postmenopausal Women. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 17 (12). pp. 3490-3498. ISSN 1055-9965

Kendall, A., Anderson, H., Dunbier, A. K., Mackay, A., Dexter, T., Urruticoechea, A., Harper-Wynne, C., Dowsett, M. (2008) Impact of estrogen deprivation on gene expression profiles of normal postmenopausal breast tissue in vivo. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 17 (4). pp. 855-863. ISSN 1055-9965

Dixon, J. M., Renshaw, L., Young, O., Murray, J., Macaskill, E. J., McHugh, M., Folkerd, E., Cameron, D. A., A'Hern, R. P., Dowsett, M. (2008) Letrozole suppresses plasma estradiol and estrone sulphate more completely than anastrozole in postmenopausal women with breast cancer. JOURNAL OF CLINICAL ONCOLOGY, 26 (10). pp. 1671-1676. ISSN 0732-183X

Dowsett, M. (2008) Optimizing the implementation of future treatment using surrogate end-points. BREAST CANCER RESEARCH, 10 (Supplement 4). ISSN 1465-5411

Ellis, M. J., Tao, Y., Luo, J. Q., A'Hern, R., Evans, D. B., Bhatnagar, A. S., Ross, H. A. C., von Kameke, A., Miller, W. R., Smith, I., Eiermann, W., Dowsett, M. (2008) Outcome prediction for estrogen receptor-positive breast cancer based on postneoadjuvant endocrine therapy tumor characteristics. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 100 (19). pp. 1380-1388. ISSN 0027-8874

Chan, M. F., Dowsett, M., Folkerd, E., Wareham, N., Luben, R., Welch, A., Bingham, S., Khaw, K. T. (2008) Past oral contraceptive and hormone therapy use and endogenous hormone concentrations in postmenopausal women. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 15 (2). pp. 332-339. ISSN 1072-3714

Attard, G., Reid, A. H. M., Yap, T. A., Raynaud, F., Dowsett, M., Settatree, S., Barrett, M., Parker, C., Martins, V., Folkerd, E., Clark, J., Cooper, C. S., Kaye, S. B., Dearnaley, D., Lee, G., de Bono, J. S. (2008) Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven. JOURNAL OF CLINICAL ONCOLOGY, 26 (28). pp. 4563-4571. ISSN 0732-183X

Urruticoechea, A., Aguilar, H., Sole, X., Capella, G., Martin, L. A., Dowsett, M., Germa-Lluch, J. R. (2008) Pre-clinical validation of early molecular markers of sensitivity to aromatase inhibitors in a mouse model of post-menopausal hormone-sensitive breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 109 (3). pp. 463-470. ISSN 0167-6806

Dowsett, M., Allred, C., Knox, J., Quinn, E., Salter, J., Wale, C., Cuzick, J., Houghton, J., Williams, N., Mallon, E., Bishop, H., Ellis, I., Larsimont, D., Sasano, H., Carder, P., Cussac, A. L., Knox, F., Speirs, V., Forbes, J., Buzdar, A. (2008) Relationship between quantitative estrogen and progesterone receptor expression and human epidermal growth factor receptor 2 (HER-2) status with recurrence in the arimidex, tamoxifen, alone or in combination trial. JOURNAL OF CLINICAL ONCOLOGY, 26 (7). pp. 1059-1065. ISSN 0732-183X

Thorpe, H., Brown, S. R., Sainsbury, J. R., Perren, T. J., Hiley, V., Dowsett, M., Nejim, A., Brown, J. M. (2008) Timing of breast cancer surgery in relation to menstrual cycle phase: no effect on 3-year prognosis: The ITS Study. BRITISH JOURNAL OF CANCER, 98 (1). pp. 39-44. ISSN 0007-0920

Tan, D. S. P., Marchio, C., Jones, R. L., Savage, K., Smith, I. E., Dowsett, M., Reis, J. S. (2008) Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients. BREAST CANCER RESEARCH AND TREATMENT, 111 (1). pp. 27-44. ISSN 0167-6806

Smith, I., Procter, M. D. Gelber, R., Guillaume, S., Feyereislova, A., Dowsett, M., Goldhirsch, A., Untch, M., Mariani, G., Baselga, J., Kaufmann, M., Cameron, D., Bell, R., Bergh, J., Coleman, R., Wardley, A., Harbeck, N., Lopez, R. I., Mallmann, P., Gelmon, K., Wilcken, N., Wist, E., Rovira, P. S., Piccart-Gebhart, M., HERA Study Team, [Group Author] (2007) 2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial. LANCET, 369 (9555). pp. 29-36. ISSN 0140-6736

Wolff, A. C., Hammond, M. E., Schwartz, J. N., Hagerty, K. L., Allred, D. C., Cote, R. J., Dowsett, M., Fitzgibbons, P. L., Hanna, W. M., Langer, A., McShane, L. M., Pail, S., Pegram, M. D., Perez, E. A., Press, M. F., Rhodes, A., Sturgeon, C., Taube, S. E., Tubbs, R., Vance, G. H., Van de Vijver, M., Wheeler, T. M., Hayes, D. F. (2007) American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. JOURNAL OF CLINICAL ONCOLOGY, 25 (1). pp. 118-145. ISSN 0732-183X

Arriola, E., Hui, E., Dowsett, M., Smith, I. E. (2007) Aromatase inhibitors and male breast cancer. CLINICAL AND TRANSLATIONAL ONCOLOGY, 9 (3). pp. 192-194. ISSN 1699-048X

Kote-Jarai, Z., Powles, T. J., Mitchell, G., Tidy, A., Ashley, S., Easton, D., Assersohn, L., Sodha, N., Salter, J., Gusterson, B., Dowsett, M., Eeles, R. (2007) BRCA1/BRCA2 mutation status and analysis of cancer family history in participants of the Royal Marsden Hospital tamoxifen chemoprevention trial. CANCER LETTERS, 247 (2). pp. 259-265. ISSN 0304-3835

Johnston, S. R. D., Martin, L. A., Leary, A., Head, J., Dowsett, M. (2007) Clinical strategies for rationale combinations of aromatase inhibitors with novel therapies for breast cancer. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 106 (1–5). pp. 180-186. ISSN 0960-0760

Jones, M. E., Folkerd, E. J., Doody, D. A., Iqbal, J., Dowsett, M., Ashworth, A., Swerdlow, A. J. (2007) Effect of delays in processing blood samples on measured endogenous plasma sex hormone levels in women. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 16 (6). pp. 1136-1139. ISSN 1055-9965

Kubista, E., Gomez, Jvmp, Dowsett, M., Foidart, J. M., Pohlodek, K., Serreyn, R., Nechushkin, M., Manikhas, A. G., Semiglazov, V. F., Hageluken, C. C. M., Singer, C. F. (2007) Effect of tibolone on breast cancer cell proliferation in postmenopausal ER+ patients: Results from STEM trial. CLINICAL CANCER RESEARCH, 13 (14). pp. 4185-4190. ISSN 1078-0432

Khaw, K. T., Dowsett, M., Folkerd, E., Bingham, S., Wareham, N., Luben, R., Welch, A., Day, N. (2007) Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) prospective population study. CIRCULATION, 116 (23). pp. 2694-2701. ISSN 0009-7322

Johnston, S. R. D., Leary, A., Martin, L. A., Smith, I. E., Dowsett, M. (2007) Enhancing endocrine response with novel targeted therapies - Why have the clinical trials to date failed to deliver on the preclinical promise? CANCER, 112 (3 Supplement S). pp. 710-717. ISSN 0008-543X

Arriola, E., Lambros, M. B. K., Jones, C., Dexter, T., Mackay, A., Tan, D. S. P., Tamber, N., Fenwick, K., Ashworth, A., Dowsett, M., Reis-Filho, J. S. (2007) Evaluation of Phi29-based whole-genome amplification for microarray-based comparative genomic hybridisation. LABORATORY INVESTIGATION, 87 (1). pp. 75-83. ISSN 0023-6837

Martin, L. A., Head, J. E., Pancholi, S., Salter, J., Quinn, E., Detre, S., Kaye, S., Howes, A., Dowsett, M., Johnston, S. R. D. (2007) The farnesyltransferase inhibitor R115777 (tipifarnib) in combination with tamoxifen acts synergistically to inhibit MCF-7 breast cancer cell proliferation and cell cycle progression in vitro and in vivo. MOLECULAR CANCER THERAPEUTICS, 6 (9). pp. 2458-2467. ISSN 1535-7163

Dowsett, M., Hanby, A. M., Laing, R., Walker, R., Natl HER2 Consultation Steering Gr, [Group Author] (2007) HER2 testing in the UK: consensus from a national consultation. JOURNAL OF CLINICAL PATHOLOGY, 60 (6). pp. 685-689. ISSN 0021-9746

Bartlett, J. M. S., Ellis, I. O., Dowsett, M., Mallon, E. A., Cameron, D. A., Johnston, S., Hall, E., A'Hern, R., Peckitt, C., Bliss, J. M., Johnson, L., Barrett-Lee, P., Ellis, P. (2007) Human epidermal growth factor receptor 2 status correlates with lymph node involvement in patients with estrogen receptor (ER) -negative, but with grade in those with ER-Positive early-stage breast cancer suitable for cytotoxic chemotherapy. JOURNAL OF CLINICAL ONCOLOGY, 25 (28). pp. 4423-4430. ISSN 0732-183X

Ellis, M. J., Dixon, M., Dowsett, M., Nagarajan, R., Mardis, E. (2007) A luminal breast cancer genome atlas: Progress and barriers. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 106 (1–5). pp. 125-129. ISSN 0960-0760

Pierga, J. Y., Reis-Filho, J. S., Cleator, S. J., Dexter, T., MacKay, A., Simpson, P., Fenwick, K., Iravani, M., Salter, J., Hills, M., Jones, C., Ashworth, A., Smith, I. E., Powles, T., Dowsett, M. (2007) Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapy. BRITISH JOURNAL OF CANCER, 96 (2). pp. 341-351. ISSN 0007-0920

Mackay, A., Urruticoechea, A., Dixon, J. M., Dexter, T., Fenwick, K., Ashworth, A., Drury, S., Larionov, A., Young, O., White, S., Miller, W. R., Evans, D. B., Dowsett, M. (2007) Molecular response to aromatase inhibitor treatment in primary breast cancer. BREAST CANCER RESEARCH, 9 (3). ISSN 1465-5411

Smith, I. E., Walsh, G., Skene, A., Llombart, A., Mayordomo, J. I., Detre, S., Salter, J., Clark, E., Magill, P., Dowsett, M. (2007) A phase II placebo-controlled trial of neoadjuvant anastrozole alone or with gefitinib in early breast cancer. JOURNAL OF CLINICAL ONCOLOGY, 25 (25). pp. 3816-3822. ISSN 0732-183X

Tworoger, S. S., Missmer, S. A., Eliassen, A. H., Barbieri, R. L., Dowsett, M., Hankinson, S. E. (2007) Physical activity and inactivity in relation to sex hormone, prolactin, and insulin-like growth factor concentrations in premenopausal women - Exercise and premenopausal hormones. CANCER CAUSES & CONTROL, 18 (7). pp. 743-752. ISSN 0957-5243

Low, Y. L., Dunning, A. M., Dowsett, M., Folkerd, E., Doody, D., Taylor, J., Bhaniani, A., Luben, R., Khaw, K. T., Wareham, N. J., Bingham, S. A. (2007) Phytoestrogen exposure is associated with circulating sex hormone levels in postmenopausal women and interact with ESR1 and NR1I2 gene variants. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 16 (5). pp. 1009-1016. ISSN 1055-9965

Anderson, H., Bulun, S., Smith, I., Dowsett, M. (2007) Predictors of response to aromatase inhibitors. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 106 (1–5). pp. 49-54. ISSN 0960-0760

Dowsett, M., Smith, I.E., Ebbs, S.R., Dixon, J.M., Skene, A., A'Hern, R., Salter, J., Detre, S., Hills, M., Walsh, G., IMPACT Trialists Group, [Group Author] (2007) Prognostic value of ki67 expression after short-term presurgical endocrine therapy for primary breast cancer. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 99 (2). pp. 167-170. ISSN 0027-8874

Kaptoge, S., Dalzell, N., Folkerd, E., Doody, D., Khaw, K. T., Beck, T. J., Loveridge, N., Mawer, E. B., Berry, J. L., Shearer, M. J., Dowsett, M., Reeve, J. (2007) Sex hormone status may modulate rate of expansion of proximal femur diameter in older women alongside other skeletal regulators. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM, 92 (1). pp. 304-313. ISSN 0021-972X

Dowsett, M., Salter, J., Hills, M., Detre, S., A'Hern, R., Smith, I. E. (2007) Short-term presurgical treatment for all? BREAST CANCER RESEARCH, 9 (Supplement 2). ISSN 1465-5411

Dowsett, M., Hanna, W. M., Kockx, M., Penault-Llorca, F., Ruschoff, J., Gutjahr, T., Habben, K., van de Vijver, M. J. (2007) Standardization of HER2 testing: results of an international proficiency-testing ring study. MODERN PATHOLOGY, 20 (5). pp. 584-591. ISSN 0893-3952

Arriola, E., Rodriguez-Pinilla, S. M., Lambros, M. B. K., Jones, R. L., James, M., Savage, K., Smith, I. E., Dowsett, M., Reis-Filho, J. S. (2007) Topoisomerase II alpha amplification may predict benefit from adjuvant anthracyclines in HER2 positive early breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 106 (2). pp. 181-189. ISSN 0167-6806

Geisler, J., Haynes, B., Ekse, D., Dowsett, M., Lonning, P. E. (2007) Total body aromatization in postmenopausal breast cancer patients is strongly correlated to plasma leptin levels. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 104 (1-2). pp. 27-34. ISSN 0960-0760

Powles, T. J., Ashley, S., Tidy, A., Dowsett, M., Smith, I. A. (2007) Twenty-year follow-up of the royal Marsden randomized, double-blinded tamoxifen breast cancer prevention trial. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 99 (4). pp. 283-290. ISSN 0027-8874

Chan, M. F., Dowsett, M., Folkerd, E., Bingham, S., Wareham, N., Luben, R., Welch, A., Khaw, K. T. (2007) Usual physical activity and endogenous sex hormones in postmenopausal women: The European prospective investigation into cancer - Norfolk Population Study. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 16 (5). pp. 900-905. ISSN 1055-9965

Smith, I. E., Dowsett, M., Yap, Y. S., Walsh, G., Lonning, P. E., Santen, R. J., Hayes, D. (2006) Adjuvant aromatase inhibitors for early breast cancer after chemotherapy-induced arnenorrhoea: Caution and suggested guidelines. JOURNAL OF CLINICAL ONCOLOGY, 24 (16). pp. 2444-2447. ISSN 0732-183X

Tworoger, S. S., Missmer, S. A., Eliassen, A. H., Spiegelman, D., Folkerd, E., Dowsett, M., Barbieri, R. L., Hankinson, S. E. (2006) The association of plasma DHEA and DHEA sulfate with breast cancer risk in predominantly premenopausal women. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 15 (5). pp. 967-971. ISSN 1055-9965

Warren, R., Skinner, J., Sala, E., Denton, E., Dowsett, M., Folkerd, E., Healey, C. S., Dunning, A., Doody, D., Ponder, B., Luben, R. N., Day, N. E., Easton, D. (2006) Associations among mammographic density, circulating sex hormones, and polymorphisms in sex hormone metabolism genes in postmenopausal women. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 15 (8). pp. 1502-1508. ISSN 1055-9965

Dowsett, M., Houghton, J., Iden, C., Salter, J., Farndon, J., A'Hern, R., Sainsbury, R., Baum, M. (2006) Benefit from adjuvant tamoxifen therapy in primary breast cancer patients according oestrogen receptor, progesterone receptor, EGF receptor and HER2 status. ANNALS OF ONCOLOGY, 17 (5). pp. 818-826. ISSN 0923-7534

Tworoger, S. S., Eliassen, A. H., Missmer, S. A., Baer, H., Rich-Edwards, J., Michels, K. B., Barbieri, R. L., Dowsett, M., Hankinson, S. E. (2006) Birthweight and body size throughout life in relation to sex hormones and prolactin concentrations in premenopausal women. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 15 (12). pp. 2494-2501. ISSN 1055-9965

Kendall, A., Dowsett, M., Folkerd, E., Smith, I. (2006) Caution: Vaginal estradiol appears to be contraindicated in postmenopausal women on adjuvant aromatase inhibitors. ANNALS OF ONCOLOGY, 17 (4). pp. 584-587. ISSN 0923-7534

Lee, J. S., Ettinger, B., Stanczyk, F. Z., Vittinghoff, E., Hanes, V., Cauley, J. A., Chandler, W., Settlage, J., Beattie, M. S., Folkerd, E., Dowsett, M., Grady, D., Cummings, S. R. (2006) Comparison of methods to measure low serum estradiol levels in postmenopausal women. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM, 91 (10). pp. 3791-3797. ISSN 0021-972X

Reis-Filho, J. S., Savage, K., Lambros, M. B. K., James, M., Steele, D., Jones, R. L., Dowsett, M. (2006) Cyclin D1 protein overexpression and CCND1 amplification in breast carcinomas: an immunohistochemical and chromogenic in situ hybridisation analysis. MODERN PATHOLOGY, 19 (7). pp. 999-1009. ISSN 0893-3952

Eastell, R., Hannon, R. A., Cuzick, J., Dowsett, M., Clack, G., Adams, J. E., ATAC Trialists Grp, [Group Author] (2006) Effect of an aromatase inhibitor on BMD and bone turnover markers: 2-year results of the Anastrozole, Tamoxifen, Alone or in Combination (ATAC) trial (18233230). JOURNAL OF BONE AND MINERAL RESEARCH, 21 (8). pp. 1215-1223. ISSN 0884-0431

Cleator, S. J., Powles, T. J., Dexter, T., Fulford, L., Mackay, A., Smith, I. E., Valgeirsson, H., Ashworth, A., Dowsett, M. (2006) The effect of the stromal component of breast tumours on prediction of clinical outcome using gene expression microarray analysis. BREAST CANCER RESEARCH, 8 (3). ISSN 1465-5411

Beattie, M. S., Costantino, J. P., Cummings, S. R., Wickerham, D. L., Vogel, V. G., Dowsett, M., Folkerd, E. J., Willett, W. C., Wolmark, N., Hankinson, S. E. (2006) Endogenous sex hormones, breast cancer risk, and tamoxifen response: An ancillary study in the NSABP Breast Cancer Prevention Trial (P-1). JOURNAL OF THE NATIONAL CANCER INSTITUTE, 98 (2). pp. 110-115. ISSN 0027-8874

Eliassen, A. H., Missmer, S. A., Tworoger, S. S., Spiegelman, D., Barbieri, R. L., Dowsett, M., Hankinson, S. E. (2006) Endogenous steroid hormone concentrations and risk of breast cancer among premenopausal women. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 98 (19). pp. 1406-1415. ISSN 0027-8874

Ellis, M. J., Too, Y., Young, O., White, S., Proia, A. D., Murray, J., Renshaw, L., Faratian, D., Thomas, J., Dowsett, M., Krause, A., Evans, D. B., Miller, W. R., Dixon, J. M. (2006) Estrogen-independent proliferation is present in estrogen-receptor HER2-positive primary breast cancer after neoadjuvant letrozole. JOURNAL OF CLINICAL ONCOLOGY, 24 (19). pp. 3019-3025. ISSN 0732-183X

Burcombe, R. D., Wilson, G., Dowsett, M., Khan, I., Richman, P. I., Daley, F., Detre, S., Makris, A. (2006) Evaluation of Ki-67 proliferation and apoptotic index before, during and after neoadjuvant chemotherapy for primary breast cancer. BREAST CANCER RESEARCH, 8 (3). ISSN 1465-5411

Cleator, S., Tsimelzon, A., Ashworth, A., Dowsett, M., Dexter, T., Powles, T., Hilsenbeck, S., Wong, H., Osborne, C. K., O'Connell, P., Chang, J. C. (2006) Gene expression patterns for doxorubicin (Adriamycin) and cyclophosphamide (Cytoxan) (AC) response and resistance. BREAST CANCER RESEARCH AND TREATMENT, 95 (3). pp. 229-233. ISSN 0167-6806

Low, Y. L., Dunning, A. M., Dowsett, M., Luben, R. N., Khaw, K. T., Wareham, N. J., Bingham, S. A. (2006) Implications of gene-environment interaction in studies of gene variants in breast cancer: An example of dietary isoflavones and the D356N polymorphism in the sex hormone-binding globulin gene. CANCER RESEARCH, 66 (18). pp. 8980-8983. ISSN 0008-5472

Amin, A. A., Huang, C. C., Reierstad, S., Lin, Z. H., Arbieva, Z., Wiley, E., Saborian, H., Haynes, B., Cotterill, H., Dowsett, M., Bulun, S. E. (2006) Paracrine-stimulated gene expression profile favors estradiol production in breast tumors. MOLECULAR AND CELLULAR ENDOCRINOLOGY, 253 (39114). pp. 44-55. ISSN 0303-7207

Dowsett, M., Smith, I. E., Ebbs, S. R., Dixon, J. M., Skene, A., Griffith, C., Boeddinghaus, I., Salter, J., Detre, S., Hills, M., Ashley, S., Francis, S., Walsh, G., A'Hern, R. (2006) Proliferation and apoptosis as markers of benefit in neoadjuvant endocrine therapy of breast cancer. CLINICAL CANCER RESEARCH, 12 (3). 1024S-1030S. ISSN 1078-0432

Folkerd, E. J., Martin, L. A., Kendall, A., Dowsett, M. (2006) The relationship between factors affecting endogenous oestradiol levels in postmenopausal women and breast cancer. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 102 (1-5). pp. 250-255. ISSN 0960-0760

Schernhammer, E. S., Kroenke, C. H., Dowsett, M., Folkerd, E., Hankinson, S. E. (2006) Urinary 6-sulfatoxymelatonin levels and their correlations with lifestyle factors and steroid hormone levels. JOURNAL OF PINEAL RESEARCH, 40 (2). pp. 116-124. ISSN 0742-3098

Martin, L. A., Pancholi, S., Chan, C. M. W., Farmer, I., Kimberley, C., Dowsett, M., Johnston, S. R. D. (2005) The anti-oestrogen ICI 182,780, but not tamoxifen, inhibits the growth of MCF-7 breast cancer cells refractory to long-term oestrogen deprivation through down-regulation of oestrogen receptor and IGF signalling. ENDOCRINE-RELATED CANCER, 12 (4). pp. 1017-1036. ISSN 1351-0088

Johnston SRD, Martin LA, Head J, Smith I, Dowsett M (2005) Aromatase inhibitors: Combinations with fulvestrant or signal transduction inhibitors as a strategy to overcome endocrine resistance. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 95 (1-5). pp. 173-181. ISSN 0960-0760

Kendall, A., Dowsett, M. (2005) Biological aspects of tamoxifen resistance versus aromatase inhibitors. MIMS ADVANCES IN BREAST CANCER, 2 . pp. 4-7.

Dowsett M, Nicholson RI, Pietras RJ (2005) Biological characteristics of the pure antiestrogen fulvestrant: overcoming endocrine resistance. BREAST CANCER RESEARCH AND TREATMENT, 93 (Supplement 1). S11-S18. ISSN 0167-6806

Dowsett, M., Folkerd, E., Doody, D., Haynes, B. (2005) The biology of steroid hormones and endocrine treatment of breast cancer. BREAST, 14 (6). pp. 452-457. ISSN 0960-9776

Dowsett M, Ebbs SR, Dixon JM, Skene A, Griffith C, Boeddinghaus I, Salter J, Detre S, Hills M, Ashley S, Francis S, Walsh G, Smith IE (2005) Biomarker changes during neoadjuvant anastrozole, tamoxifen, or the combination: Influence of hormonal status and HER-2 in breast cancer - A study from the IMPACT trialists. JOURNAL OF CLINICAL ONCOLOGY, 23 (11). pp. 2477-2492. ISSN 0732-183X

Banerjee, S., Smith, I. E., Folkerd, L., Iqbal, J., Barker, P., Dowsett, M. (2005) Comparative effects of anastrozole, tamoxifen alone and in combination on plasma lipids and bone-derived resorption during neoadjuvant therapy in the impact trial. ANNALS OF ONCOLOGY, 16 (10). pp. 1632-1638. ISSN 0923-7534

Ring, A. E., Zabaglo, L., Ormerod, M. G., Smith, I. E., Dowsett, M. (2005) Detection of circulating epithelial cells in the blood of patients with breast cancer: comparison of three techniques. BRITISH JOURNAL OF CANCER, 92 (5). pp. 906-912. ISSN 0007-0920

Martin, L. A., Farmer, I., Johnston, S. R. D., Ali, S., Dowsett, M. (2005) Elevated ERK1/ERK2/estrogen receptor cross-talk enhances estrogen-mediated signaling during long-term estrogen deprivation. ENDOCRINE-RELATED CANCER, 12 (Supplement 1). S75-S84. ISSN 1351-0088

Dowsett, M., Johnston, S., Martin, L. A., Salter, J., Hills, M., Detre, S., Gutierrez, M. C., Mohsin, S. K., Shout, J., Allred, D. C., Osborne, C. K., Smith, I. (2005) Growth factor signalling and response to endocrine therapy: the Royal Marsden Experience. ENDOCRINE-RELATED CANCER, 12 (Supplement 1). S113-S117. ISSN 1351-0088

Johnston SR, Martin LA, Dowsett M (2005) Life following aromatase inhibitors - where now for endocrine sequencing?. BREAST CANCER RESEARCH AND TREATMENT, 93 (Supplement 1). S19-S25. ISSN 0167-6806

Dowsett M, Martin LA, Smith I, Johnston S (2005) Mechanisms of resistance to aromatase inhibitors. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 95 (1-5). pp. 167-172. ISSN 0960-0760

Gutierrez MC, Detre S, Johnston S, Mohsin SK, Shou JN, Allred DC, Schiff R, Osborne CK, Dowsett M (2005) Molecular changes in tamoxifen-resistant breast cancer: Relationship between estrogen receptor, HER-2, and p38 mitogen-activated protein kinase. JOURNAL OF CLINICAL ONCOLOGY, 23 (11). pp. 2469-2476. ISSN 0732-183X

Smith IE, Dowsett M, Ebbs SR, Dixon JM, Skene A, Blohmer JU, Ashley SE, Francis S, Boeddinghaus I, Walsh G (2005) Neoadjuvant treatment of postmenopausal breast cancer with anastrozole, tamoxifen, or both in combination: The Immediate Preoperative Anastrozole, Tamoxifen, or Combined with Tamoxifen (IMPACT) multicenter double-blind randomized trial. JOURNAL OF CLINICAL ONCOLOGY, 23 (22). pp. 5108-5116. ISSN 0732-183X

Low, Y. L., Taylor, J. I., Grace, P. B., Dowsett, M., Scollen, S., Dunning, A. M., Mulligan, A. A., Welch, A. A., Luben, R. N., Khaw, K. T., Day, N. E., Wareham, N. J., Bingham, S. A. (2005) Phytoestrogen exposure correlation with plasma estradiol in postmenopausal women in European Prospective Investigation of Cancer and Nutrition-Norfolk may involve diet-gene interactions. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 14 (1). pp. 213-220. ISSN 1055-9965

Low, Y. L., Taylor, J. I., Grace, P. B., Dowsett, M., Folkerd, E., Doody, D., Dunning, A. M., Scollen, S., Mulligan, A. A., Welch, A. A., Luben, R. N., Khaw, K. T., Day, N. E., Wareham, N. J., Bingham, S. A. (2005) Polymorphisms in the CYP19 gene may affect the positive correlations between serum and urine phytoestrogen metabolites and plasma androgen concentrations in men. JOURNAL OF NUTRITION, 135 (11). pp. 2680-2686. ISSN 0022-3166

Chen B, Gajdos C, Dardes R, Kidwai N, Johnston SRD, Dowsett M, Jordan VC (2005) Potential of endogenous estrogen receptor beta to influence the selective ER modulator ER beta complex. INTERNATIONAL JOURNAL OF ONCOLOGY, 27 (2). pp. 327-335. ISSN 1019-6439

Howell A, Cuzick J, Baum M, Buzdar A, Dowsett M, Forbes JF, Hoctin-Boes G, Houghton I, Locker GY, Tobias JS, ATAC Trialists' Group (2005) Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer. LANCET, 365 (9453). pp. 60-62. ISSN 0140-6736

Dowsett, M., Cuzick, J., Wale, C., Howell, T., Houghton, J., Baum, M. (2005) Retrospective analysis of time to recurrence in the ATAC trial according to hormone receptor status: An hypothesis-generating study. JOURNAL OF CLINICAL ONCOLOGY, 23 (30). pp. 7512-7517. ISSN 0732-183X

Dowsett, M., Smith, I. E., Ebbs, S. R., Dixon, J. M., Skene, A., Griffith, C., Boeddinghaus, I., Salter, J., Detre, S., Hills, M., Ashley, S., Francis, S., Walsh, G. on behalf of the IMPACT Trialists (2005) Short-term changes in Ki-67 during neoadjuvant treatment of primary breast cancer with anastrozole or tamoxifen alone or combined correlate with recurrence-free survival. CLINICAL CANCER RESEARCH, 11 (2). 951S-958S. ISSN 1078-0432

Dowsett M (2005) Tailored endocrine therapy - ready for clinical practice. EJC SUPPLEMENTS, 3 (3). pp. 255-258. ISSN 1359-6349

Esserman, L. J., Ozanne, E. M., Dowsett, M., Slingerland, J. M. (2005) Tamoxifen may prevent both ER+ and ER- breast cancers and select for ER- carcinogenesis: an alternative hypothesis. BREAST CANCER RESEARCH, 7 (6). R1153-R1158. ISSN 1465-5411

Piccart-Gebhart, M. J., Procter, M., Leyland-Jones, B., Goldhirsch, A., Untch, M., Smith, I., Gianni, L., Baselga, J., Bell, R., Jackisch, C., Cameron, D., Dowsett, M., Barrios, C. H., Steger, G., Huang, C. S., Andersson, M., Inbar, M., Lichinitser, M., Lang, I., Nitz, U., Iwata, H., Thomssen, C., Lohrisch, C., Suter, T. M., Ruschoff, J., Suto, T., Greatorex, V., Ward, C., Straehle, C., McFadden, E., Dolci, M. S., Gelber, R. D. (2005) Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. NEW ENGLAND JOURNAL OF MEDICINE, 353 (16). pp. 1659-1672. ISSN 0028-4793

Geisler J, Haynes B, Anker G, Helle H, Ekse D, Dowsett M, Lonning PE (2005) Treatment with high-dose estrogen (diethylstilbestrol) significantly decreases plasma estrogen and androgen levels but does not influence in vivo aromatization in postmenopausal breast cancer patients. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 96 (5). pp. 415-422. ISSN 0960-0760

Dixon JM, Jackson J, Hills M, Renshaw L, Cameron DA, Anderson TJ, Miller WR, Dowsett M (2004) Anastrozole demonstrates clinical and biological effectiveness in oestrogen receptor-positive breast cancers, irrespective of the erbB2 status. EUROPEAN JOURNAL OF CANCER, 40 (18). pp. 2742-2747. ISSN 0959-8049

Dowsett M (2004) Biomarker investigations from the ATAC trial: the role of TA01. BREAST CANCER RESEARCH AND TREATMENT, 87 (Supplement 1). S11-S18. ISSN 0167-6806

Johnston SRD, Gumbrell LA, Evans TRJ, Coleman RE, Smith IE, Twelves CJ, Soukop M, Rea DW, Earl HM, Howell A, Jones A, Canney P, Powles TJ, Haynes BP, Nutley B, Grimshaw R, Jarman M, Halbert GW, Brampton M, Haviland J, Dowsett M, Coombes RC (2004) A Cancer Research (UK) randomized phase II study of idoxifene in patients with locally advanced/metastatic breast cancer resistant to tamoxifen. CANCER CHEMOTHERAPY AND PHARMACOLOGY, 53 (4). pp. 341-348. ISSN 0344-5704

Dowsett M (2004) Designing the future shape of breast cancer diagnosis, prognosis and treatment. BREAST CANCER RESEARCH AND TREATMENT, 87 (Supplement 1). S27-S29. ISSN 0167-6806

Atkinson, C., Compston, J. E., Day, N. E., Dowsett, M., Bingham, S. A. (2004) The effects of phytoestrogen isoflavones on bone density in women: a double-blind, randomized, placebo-controlled trial. THE AMERICAN JOURNAL OF CLINICAL NUTRITION, 79 (2). pp. 326-333. ISSN 0002-9165

Parton M, Dowsett M, Ashley S, Hills M, Lowe F, Smith IE (2004) High incidence of HER-2 positivity in inflammatory breast cancer. BREAST, 13 (2). pp. 97-103. ISSN 0960-9776

O'Donnell, A., Judson, I., Dowsett, M., Raynaud, F., Dearnaley, D., Mason, M., Harland, S., Robbins, A., Halbert, G., Nutley, B., Jarman, M. (2004) Hormonal impact of the 17 alpha-hydroxylase/C-17,C-20-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer. BRITISH JOURNAL OF CANCER, 90 (12). pp. 2317-2325. ISSN 0007-0920

Grace, P. B., Taylor, J. I., Low, Y. L., Luben, R. N., Mulligan, A. A., Botting, N. P., Dowsett, M., Welch, A. A., Khaw, K. T., Wareham, N. J., Day, N. E., Bingham, S. A. (2004) Phytoestrogen concentrations in serum and spot urine as biomarkers for dietary phytoestrogen intake and their relation to breast cancer risk in European prospective Investigation of Cancer and Nutrition-Norfolk. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 13 (5). pp. 698-708. ISSN 1055-9965

Dunning, A. M., Dowsett, M., Healey, C. S., Tee, L., Luben, R. N., Folkerd, E., Novik, K. L., Kelemen, L., Ogata, S., Pharoah, P. D. P., Easton, D. F., Day, N. E., Ponder, B. A. J. (2004) Polymorphisms associated with circulating sex hormone levels in postmenopausal women. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 96 (12). pp. 936-945. ISSN 0027-8874

Dowsett M (2004) Translational research and the changing face of breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 87 (Supplement 1). S1-S2. ISSN 0167-6806

Baum, M., Buzdar, A., Cuzick, J., Forbes, J., Houghton, J., Howell, A., Sahmoud, T., [The ATAC (Arimidex, Tamoxifen Alone or in Combination) Trialists' Group (includes M Dowsett)] (2003) Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early-stage breast cancer. Results of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial efficacy and safety update analyses. CANCER, 98 (9). pp. 1802-1810. ISSN 0008-543X

Key, T. J., Appleby, P. N., Reeves, G. K., Roddam, A., Dorgan, J. F., Longcope, C., Stanczyk, F. Z,. Stephenson, H. E., Falk, R. T., Miller, R., Schatzkin, A., Allen, D. S., Fentiman, I. S., Key, T. J., Wang, D. Y., Dowsett, M., Thomas, H. V., Hankinson, S. E., Toniolo, P., Koenig, K., Shore, R. E., Zeleniuch-Jacquotte, A., Berrino, F., Muti, P., Micheli, A., Krogh, V., Sieri, S., Pala, V., Venturelli, E., Secreto, G., Barrett-Connor, E., Laughlin, G. A., Kabuto, M., Akiba, S., Stevens, R. G., Neriishi, K., Land, C. E., Cauley, J. A., Kuller, L. H., Cummings, S. R., Helzlsouer, K. J., Alberg, A. J., Bush, T. L., Comstock, G. W., Gordon, G. B., Miller, S. R. (2003) Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 95 (16). pp. 1218-1226. ISSN 0027-8874

Zabaglo, L., Ormerod, M. G., Parton, M., Ring, A., Smith, I. E., Dowsett, M. (2003) Cell filtration-laser scanning cytometry for the characterisation of circulating breast cancer cells. CYTOMETRY, 55 (2). pp. 102-108. ISSN 0196-4763

Detre, S., Riddler, S., Salter, J., A'Hern, R., Dowsett, M., Johnston, S. R. D. (2003) Comparison of the selective estrogen receptor modulator arzoxifene (LY353381) with tamoxifen on tumor growth and biomarker expression in an MCF-7 human breast cancer xenograft model. CANCER RESEARCH, 63 (19). pp. 6516-6522. ISSN 0008-5472

Davies, G., Salter, J., Hills, M., Martin, L. A., Sacks, N., Dowsett, M. (2003) Correlation between cyclooxygenase-2 expression and angiogenesis in human breast cancer. CLINICAL CANCER RESEARCH, 9 (7). pp. 2651-2656. ISSN 1078-0432

Dowsett M, Bartlett J, Ellis IO, Salter J, Hills M, Mallon E, Watters AD, Cooke T, Paish C, Wencyk PM, Pinder SE (2003) Correlation between immunohistochemistry (HercepTest) and fluorescence in situ hybridization (FISH) for HER-2 in 426 breast carcinomas from 37 centres. JOURNAL OF PATHOLOGY, 199 (4). pp. 418-423. ISSN 0022-3417

Archer, C. D., Parton, M., Smith, I. E., Ellis, P. A., Salter, J., Ashley, S., Gui, G., Sacks, N., Ebbs, S. R., Allum, W., Nasiri, N., Dowsett, M. (2003) Early changes in apoptosis and proliferation following primary chemotherapy for breast cancer. BRITISH JOURNAL OF CANCER, 89 (6). pp. 1035-1041. ISSN 0007-0920

Dowsett M (2003) Efforts to link biological and clinical breast cancer research. BREAST, 12 (6). pp. 442-446. ISSN 0960-9776

Martin, L. A., Farmer, I., Johnston, S. R. D., Ali, S., Marshall, C., Dowsett, M. (2003) Enhanced estrogen receptor (ER) alpha, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation. JOURNAL OF BIOLOGICAL CHEMISTRY, 278 (33). pp. 30458-30468. ISSN 0021-9258

Dowsett M, Haynes BP (2003) Hormonal effects of aromatase inhibitors: focus on premenopausal effects and interaction with tamoxifen. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 86 (3-5). pp. 255-263. ISSN 0960-0760

Ring A, Dowsett M (2003) Human epidermal growth factor receptor-2 and hormonal therapies: clinical implications. CLINICAL BREAST CANCER, 4 (Supplement 1). S34-S41. ISSN 1526-8209

Zabaglo, L., Ormerod, M. G., Dowsett, M. (2003) Measurement of proliferation marker Ki67 in breast tumour FNAs using laser scanning cytometry in comparison to conventional immunocytochemistry. CYTOMETRY, 56 (1). pp. 55-61. ISSN 0196-4763

Johnston SRD, Hickish T, Ellis P, Houston S, Kelland L, Dowsett M, Salter J, Michiels B, Perez-Ruixo JJ, Palmer P, Howes A (2003) Phase II study of the efficacy and tolerability of two dosing regimens of the farnesyl transferase inhibitor, R115777, in advanced breast cancer. JOURNAL OF CLINICAL ONCOLOGY, 21 (13). pp. 2492-2499. ISSN 0732-183X

Assersohn L, Salter J, Powles TJ, A'Hern R, Makris A, Gregory RK, Chang J, Dowsett M (2003) Studies of the potential utility of Ki67 as a predictive molecular marker of clinical response in primary breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 82 (2). pp. 113-123. ISSN 0167-6806

The ATAC Trialists Group (Dowsett M Steering Committee Member) (2002) Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial. LANCET, 360 (9336). pp. 817-824. ISSN 0140-6736

Cleator, S., Parton, M., Dowsett, M. (2002) The biology of neoadjuvant chemotherapy for breast cancer. ENDOCRINE-RELATED CANCER, 9 (3). pp. 183-195. ISSN 1351-0088

Parton, M., Krajewski, S., Smith, I., Krajewska, M., Archer, C., Naito, M., Ahern, R., Reed, J., Dowsett, M. (2002) Co-ordinate expression of apoptosis associated proteins in human breast cancer before and during chemotherapy. CLINICAL CANCER RESEARCH, 8 (7). pp. 2100-2108. ISSN 1078-0432

Harper-Wynne CL, Sacks NPM, Shenton K, MacNeill FA, Sauven P, Laidlaw IJ, Rayter Z, Miall S, Howes A, Salter J, Hills MJ, Lowe FM, A'Hern R, Nasiri N, Doody D, Iqbal J, Dowsett M (2002) Comparison of the systemic and intratumoral effects of tamoxifen and the aromatase inhibitor vorozole in postmenopausal patients with primary breast cancer. JOURNAL OF CLINICAL ONCOLOGY, 20 (4). pp. 1026-1035. ISSN 0732-183X

Di Leo A, Dowsett M, Horten B, Penault-Llorca F (2002) Current status of HER2 testing. ONCOLOGY, 63 (Supplement 1). pp. 25-32. ISSN 0030-2414

Harper-Wynne, C., Ross, G., Sacks, N., Salter, J., Nasiri, N., Iqbal, J., A'Hern, R., Dowsett, M. (2002) Effects of the aromatase inhibitor letrozole on normal breast epithelial cell proliferation and metabolic indices in postmenopausal women A pilot study for breast cancer prevention. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 11 (7). pp. 614-621. ISSN 1055-9965

Endogenous Hormones and Breast Cancer Collaborative Group (Dowsett M member) (2002) Endogenous Sex Hormones and Breast Cancer in Postmenopausal Women: Reanalysis of Nine Prospective Studies. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 94 (8). pp. 606-616. ISSN 0027-8874

Assersohn, L., Gangi, L., Zhao, Y. D., Dowsett, M., Simon, R., Powles, T. J., Liu, E. T. (2002) The feasibility of using fine needle aspiration from primary breast cancers for cDNA microarray analyses. CLINICAL CANCER RESEARCH, 8 (3). pp. 794-801. ISSN 1078-0432

IBIS Investigators (Dowsett M member), Cuzick J (2002) First results from the International Breast cancer Intervention Study (IBIS-1): a randomised prevention trial. LANCET, 360 (9336). pp. 817-824. ISSN 0140-6736

Bundred NJ, Anderson E, Nicholson RI, Dowsett M, Dixon M, Robertson JFR (2002) Fulvestrant, an estrogen receptor downregulator, reduces cell turnover index more effectively than tamoxifen. ANTICANCER RESEARCH, 22 (4). pp. 2317-2319. ISSN 0250-7005

Geisler J, Haynes B, Anker G, Dowsett M, Lonning PE (2002) Influence of letrozole and anastrozole on total body aromatization and plasma estrogen levels in postmenopausal breast cancer patients evaluated in a randomized, cross-over study. JOURNAL OF CLINICAL ONCOLOGY, 20 (3). pp. 751-757. ISSN 0732-183X

Geisler J, Dowsett M, Lonning PE (2002) Letrozole is more effective than anastrozole in suppressing total body aromatization and plasma strogen levels in postmenopausal breast cancer patients. AMERICAN JOURNAL OF ONCOLOGY REVIEWS, 1 . pp. 99-102.

Chan CMW, Martin LA, Johnston SRD, Ali S, Dowsett M (2002) Molecular changes associated with the acquisition of oestrogen hypersensitivity in MCF-7 breast cancer cells on long-term oestrogen deprivation. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 81 (4-5). pp. 333-341. ISSN 0960-0760

Boeddinghaus IM, Dowsett M (2001) Comparative clinical pharmacology and pharmacokinetic interactions of aromatase inhibitors. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 79 (1-5). pp. 85-91. ISSN 0960-0760

Robertson, J. F., Nicholson, R. I., Bundred, N. J., Anderson, E., Rayter, Z., Dowsett, M., Fox, J. N., Gee, J. M. W., Webster, A., Wakeling, A. E., Morris, C., Dixon, M. (2001) Comparison of the short-term biological effects of 7 alpha-[9- (4,4,5,5,5-pentafluoropentylsulfinyl)-nonyl]estra-1,3,5, (10)-triene-3,17 beta-diol (Faslodex) versus tamoxifen in postmenopausal women with primary breast cancer. CANCER RESEARCH, 61 (18). pp. 6739-6746. ISSN 0008-5472

Dowsett, M., Bundred, N. J., Decensi, A., Sainsbury, R. C., Lu, Y. L., Hills, M. J., Cohen, F. J., Veronesi, P., O'Brien, M. E. R., Scott, T., Muchmore, D. B. (2001) Effect of raloxifene on breast cancer cell Ki67 and apoptosis: A double-blind, placebo-controlled, randomized clinical trial in postmenopausal patients. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 10 (9). pp. 961-966. ISSN 1055-9965

Dowsett, M., Harper-Wynne, C., Boeddinghaus, I., Salter, J., Hills, M., Dixon, M., Ebbs, S., Gui, G., Sacks, N., Smith, I. (2001) HER-2 amplification impedes the antioproliferative effects of hormone therapy in oestrogen receptor-positive primary breast cancer. CANCER RESEARCH, 61 (23). pp. 8452-8458. ISSN 0008-5472

Geisler, J., Detre, S., Berntsen, H., Ottestad, L., Lindtjorn, B., Dowsett, M., Lonning, P. E. (2001) Influence of neoadjuvant anastrozole (Arimidex) on intratumoral estrogen levels and proliferation markers in patients with locally advanced breast cancer. CLINICAL CANCER RESEARCH, 7 (5). pp. 1230-1236. ISSN 1078-0432

Dowsett, M. (2001) Overexpression of HER-2 as a resistance mechanism to hormonal therapy for breast cancer. ENDOCRINE-RELATED CANCER, 8 (3). pp. 191-195. ISSN 1351-0088

The ATAC Trialists Group (Dowsett M member) (2001) Pharmacokinetics of anastrozole and tamoxifen alone, and in combination, during adjuvant endocrine therapy for early breast cancer in postmenopausal women: a sub-protocol of the 'Arimidex (TM) and Tamoxifen Alone or in Combination' (ATAC) trial. BRITISH JOURNAL OF CANCER, 85 (3). pp. 317-324. ISSN 0007-0920

Kelland, L. R., Smith, V., Valenti, M., Patterson, L., Clarke, P. A., Detre, S., End, D., Howes, A. J., Dowsett, M., Workman, P., Johnston, S. R. D. (2001) Preclinical antitumor activity and pharmacodynamic studies with the farnesylprotein transferase inhibitor R115777 in human breast cancer. CLINICAL CANCER RESEARCH, 7 (11). pp. 3544-3550. ISSN 1078-0432

Harper-Wynne C, Dowsett M (2001) Recent advances in the clinical application of aromatase inhibitors. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 76 (1-5). pp. 179-186. ISSN 0960-0760

Book Section

Dowsett, M. (2008) Factors Predicting Response and Resistance to Endocrine Therapy of Breast Cancer. In: American Society of Clinical Oncology 2008 Educational Book. American Society of Clinical Oncology, pp. 14-17.

Winer EP, Carey LA, Dowsett M, Tripathy D (2005) Beyond Anatomic Staging: Are We Ready to Take the Leap to Molecular Classification? In: American Society of Clinical Oncology Educational Book 2005. American Society of Clinical Oncology, pp. 46-59.

Dowsett, M. (2005) Biology of estrogen-dependent breast cancer (Chapter 1). In: Aromatase Inhibitors for the Treatment of Breast Cancer. CMP HealthCare Media, Manhasset, New York, USA, pp. 1-13.

Dowsett M, Garber J (2004) Aromatase Inhibitors as Chemopreventives of Breast Cancer. In: Cancer Chemoprevention Volume 1: Promising Cancer Chemopreventive Agents. Cancer Drug Discovery and Development . Humana Press, Totowa, USA, pp. 231-244. ISBN 978-158829076-2

Dowsett M (2004) Clinical trials with aromatase inhibitors for the prevention of breast cancer. In: Advances in Endocrine Therapy of Breast Cancer. Informa Healthcare, New York, USA, pp. 189-202. ISBN 978-082472228-9

Dowsett M, Miller WR. (2003) Endocrinology. In: Classic Papers in Breast Disease. Martin Dunitz, London, pp. 283-304. ISBN 978-190186583-7

Boeddinghaus I, Johnston SRD, Dowsett M. (2003) Hormones and cancer. In: Cancer in Primary Care. Taylor and Francis, London, pp. 75-80. ISBN 978-190186526-4

Shenton K, Dowsett M, Dukes M (2002) Clinical Utility of Aromatase Inhibitors. In: Hormone Therapy in Breast and Prostate Cancer. Cancer Drug Discovery and Development . Humana Press, Totowa, USA, pp. 265-292. ISBN 978-089603673-4

Boeddinghaus I, Dowsett M. (2002) Recent developments in the hormonal treatment of breast cancer. In: Breast Cancer: Prognosis, Treatment, and Prevention. Informa Healthcare, New York, USA, pp. 343-372. ISBN 978-082470712-5

Dowsett M. (2002) Surrogate and Intermediate Markers in Early Breast Cancer. In: Endocrine Therapy in Breast Cancer. Marcel Dekker Inc., New York, USA, pp. 157-169. ISBN 978-082470787-3

Dowsett M (2001) Aromatase inhibition: the outcome of twenty years of drug development. In: Aromatase Inhibition and Breast Cancer. Informa Healthcare, New York, USA, pp. 3-15. ISBN 978-082470412-4

Harper-Wynne C, Dowsett M (2001) Evidentiary basis for breast cancer prevention. In: The Effective Management of Breast Cancer. UK Key Advances in Clinical Practice Series . Aesculapius Medical Press, London, pp. 29-44. ISBN 978-190304413-1

Dowsett M, Johnston SRD. (2001) Hormone therapy. In: Oxford Textbook of Oncology (2nd ed.). Oxford University Press., Oxford, UK, pp. 819-833. ISBN 978-019262926-5

Johston SRD, Smith IE, Dowsett M (2001) Place of aromatase inhibitors in the endocrine therapy of breast cancer. In: Aromatase Inhibition and Breast Cancer. Informa Healthcare, New York, USA, pp. 29-49. ISBN 978-082470412-4

Editorial

Dowsett, M. (2008) Introduction to sessions on 'Predicting personal risk for breast cancer'. [Editorial]

Dowsett, M. (2007) Chairperson's introduction. [Editorial]

Dowsett, M., Miller, W. R. (2007) Introduction to sessions on Personalising treatment. [Editorial]

Dowsett, M. (2006) Estrogen receptor: Methodology matters. [Editorial]

Come, S. E., Buzdar, A. U., Ingle, J. N., Arteaga, C. L., Brown, M., Dowsett, M., Hilsenbeck, S. G., Kumar, R., Johnston, S. R. D., Lee, A. V., Paik, S., Pritchard, K. I., Winer, E. P., Hart, C. (2006) Proceedings of the Fifth International Conference on Recent Advances and Future Directions in Endocrine Therapy for Breast Cancer: Conference summary statement. [Editorial]

Dowsett M, Ashworth A (2003) New biology of the oestrogen receptor. [Editorial]

Come, S. E., Buzdar, A. U., Arteaga, C. L., Brodie, A. M., Davidson, N. E., Dowsett, M., Ingle, J. N., Johnston, S. R. D., Lee, A. V., Osborne, C. K., Pritchard, K. I., Vogel, V. G., Winer, E. P., Hart, C. S. (2003) Second international conference on recent advances and future directions in endocrine manipulation of breast cancer: summary consensus statement. [Editorial]

Dowsett, M., Howell, A. (2002) Breast cancer: Aromatase inhibitors take on tamoxifen. [Editorial]

Harousseau, J. L., Mundy, G. R., Durie, B., Powles, R., Catovsky, D., Kulkarni, S., Dowsett, M., Goyal, S. (2001) International grand round. Myeloma Grand Round. [Editorial]

Letter

Lonning, P. E., Dowsett, M. (2010) Endocrine Effects of Aromatase Inhibitors. [Letter]

Bartlett, J. M. S., Ellis, I. O., Dowsett, M., Mallon, E. A., Cameron, D. A., Johnston, S., Hall, E., A'Hern, R., Peckitt, C., Bliss, J. M., Johnson, L., Barrett-Lee, P., Ellis, P. (2008) In early-stage breast cancer, the estrogen receptor interacts with correlation between human epidermal growth factor receptor 2 status and age at diagnosis, tumor grade, and lymph node involvement - In reply. [Letter]

Dowsett, M., Smith, I. E. (2007) Re: Prognostic value of Ki67 expression after short-term presurgical endocrine therapy for primary breast cancer - Response. [Letter]

Powles, T. J., Ashley, S., Smith, I. E., Dowsett, M. (2007) Response: Re: Treatment of Human Epidermal Growth Factor Receptor 2-Overexpressing Breast Cancer Xenografts With Multiagent Human Epidermal Growth Factor Receptor-Targeted Therapy. [Letter]

Dowsett, M., Urruticoechea, A., Smith, I. E. (2006) Ki-67 correlates with in vivo bromodeoxyuridine labeling index in operable breast cancer - Reply. [Letter]

Dowsett, M., Cuzick, J., Wale, C., Howell, T., Houghton, J., Baum, M., Buzdar, A. (2006) Progesterone receptor and human epidermal growth factor receptor 2 status: An independent influence on the efficacy of endocrine therapy in breast cancer? Reply. [Letter]

Dunning, A. M., Dowsett, M., Healey, C. S., Luben, R. N., Folkerd, E., Pharoah, P. D. P., Easton, D. F., Bruce, N. E. D., Ponder, A. J. (2005) Re: Polymorphisms associated with circulating sex hormone levels in postmenopausal women - Response. [Letter]

Cuzick J, Buzdar A, Baum M, Bianco R, Coleman R, Constenla M, Distler W, Dowsett M, Forbes J, Guastalla JP, Houghton J, Williams N, Howell A, Locker G, MacKey J, Sainsbury R, Tobias J (2004) Adjuvant use of anastrozole in breast cancer. [Letter]

Lonning PE, Geisler J, Dowsett M (2002) Endocrine effects of nonsteroidal aromatase inhibitors and their clinical impact - Reply. [Letter]

Monograph

Henderson C, Piccart MJ, Baum M, Berry DA, Coombes RC, Dowsett M, Howell A, Ingle JN, Jänicke F, Kaufmann M, Pritchard KI, Rose C, Tu D, Winer EP (2004) The evolving role of aromatase inhibitors in adjuvant breast cancer therapy. Other. UNKNOWN.

Review Article

Leary, A. F., Hanna, W. M., van de Vijver, M. J., Penault-Llorca, F., Ruschoff, J., Osamura, R. Y., Bilous, M., Dowsett, M. (2009) Value and Limitations of Measuring HER-2 Extracellular Domain in the Serum of Breast Cancer Patients. JOURNAL OF CLINICAL ONCOLOGY, 27 (10). pp. 1694-1705. ISSN 0732-183X

Urruticoechea, A., Arnedos, M., Walsh, G., Dowsett, M., Smith, I. E. (2008) Ovarian protection with goserelin during adjuvant chemotherapy for pre-menopausal women with early breast cancer (EBC). BREAST CANCER RESEARCH AND TREATMENT, 110 (3). pp. 411-416. ISSN 0167-6806

Wolff, A. C., Berry, D., Carey, L. A., Colleoni, M., Dowsett, M., Ellis, M., Garber, J. E., Mankoff, D., Paik, S., Pusztai, L., Smith, M. L., Zujewski, J. (2008) Research issues affecting preoperative systemic therapy for operable breast cancer. JOURNAL OF CLINICAL ONCOLOGY, 26 (5). pp. 806-813. ISSN 0732-183X

Santen, R. J., Boyd, N. F., Chlebowski, R. T., Cummings, S., Cuzick, J., Dowsett, M., Easton, D., Forbes, J. F., Key, T., Hankinson, S. E., Howell, A., Ingle, J. (2007) Critical assessment of new risk factors for breast cancer: considerations for development of an improved risk prediction model. ENDOCRINE-RELATED CANCER, 14 (2). pp. 169-187. ISSN 1351-0088

Kendall, A., Folkerd, E. J., Dowsett, M. (2007) Influences on circulating oestrogens in postmenopausal women: Relationship with breast cancer. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 103 (2). pp. 99-109. ISSN 0960-0760

Banerjee, S., Dowsett, M., Ashworth, A., Martin, L. A. (2007) Mechanisms of Disease: angiogenesis and the management of breast cancer. NATURE CLINICAL PRACTICE ONCOLOGY, 4 (9). pp. 536-550. ISSN 1743-4254

Leary, A., Dowsett, M. (2006) Combination therapy with aromatase inhibitors: the next era of breast cancer treatment? BRITISH JOURNAL OF CANCER, 95 (6). pp. 661-666. ISSN 0007-0920

Kendall, A., Dowsett, M. (2006) Novel concepts for the chemoprevention of breast cancer through aromatase inhibition. ENDOCRINE-RELATED CANCER, 13 (3). pp. 827-837. ISSN 1351-0088

Dowsett, M., Folkerd, E. (2005) Deficits in plasma oestradiol measurement in studies and management of breast cancer. BREAST CANCER RESEARCH, 7 (1). pp. 1-4. ISSN 1465-5411

Urruticoechea, A., Smith, I. E., Dowsett, M. (2005) Proliferation marker Ki-67 in early breast cancer. JOURNAL OF CLINICAL ONCOLOGY, 23 (28). pp. 7212-7220. ISSN 0732-183X

Ring A, Smith IE, Dowsett M (2004) Circulating tumour cells in breast cancer. LANCET ONCOLOGY, 5 (2). pp. 79-88. ISSN 1470-2045

Howell, A., Dowsett, M. (2004) Endocrinology and hormone therapy in breast cancer - Aromatase inhibitors versus antioestrogens. BREAST CANCER RESEARCH, 6 (6). pp. 269-274. ISSN 1465-5411

Ring, A., Dowsett, M. (2004) Mechanisms of tamoxifen resistance. ENDOCRINE-RELATED CANCER, 11 (4). pp. 643-658. ISSN 1351-0088

Atkinson, C., Warren, R. M. L., Sala, E., Dowsett, M., Dunning, A. M., Healey, C. S., Runswick, S., Day, N. E., Bingham, S. A. (2004) Red clover-derived isoflavones and mammographic breast density: a double-blind, randomized, placebo-controlled trial [ISRCTN42940165]. BREAST CANCER RESEARCH, 6 (3). R170-R179. ISSN 1465-5411

Saunders Y, Ross JR, Broadley KE, Edmonds PM, Patel S, on behalf of Steering Group (includes Dearnaley D, Dowsett M, Ahern R, Powles T, Johnston S) (2004) Systematic review of bisphosphonates for hypercalcaemia of malignancy. PALLIATIVE MEDICINE, 18 (5). pp. 418-431. ISSN 0269-2163

Ellis, I. O,. Bartlett, J., Dowsett, M., Humphreys, S., Jasani, B., Miller, K., Pinder, S. E., Rhodes, A., Walker, R. (2004) Updated recommendations for HER2 testing in the UK. JOURNAL OF CLINICAL PATHOLOGY, 57 (3). pp. 233-237. ISSN 0021-9746

Johnston SRD, Dowsett M (2003) Aromatase inhibitors for breast cancer: Lessons from the laboratory. NATURE REVIEWS CANCER, 3 (11). pp. 821-831. ISSN 1474-175X

Bilous, M., Dowsett, M., Hanna, W., Isola, J., Lebeau, A., Moreno, A., Penault-Llorca, F., Ruschoff, J., Tomasic, G., de Vijver, M. V. (2003) Current perspectives on HER2 testing: A review of national testing guidelines. MODERN PATHOLOGY, 16 (2). pp. 173-182. ISSN 0893-3952

Smith, I. E., Dowsett, M. (2003) Drug therapy: Aromatase inhibitors in breast cancer. NEW ENGLAND JOURNAL OF MEDICINE, 348 (24). pp. 2431-2442. ISSN 0028-4793

Johnston, S. R. D., Head, J., Pancholi, S., Detre, S., Martin, L. A., Smith, I. E., Dowsett, M. (2003) Integration of signal transduction inhibitors with endocrine therapy: An approach to overcoming hormone resistance in breast cancer. CLINICAL CANCER RESEARCH, 9 (1). 524S-532S. ISSN 1078-0432

Dowsett M (2003) Origin and characteristics of adverse events in aromatase inhibition therapy for breast cancer. SEMINARS IN ONCOLOGY, 30 (4 Supplement 14). pp. 58-69. ISSN 0093-7754

Haynes BP, Dowsett M, Miller WR, Dixon JM, Bhatnagar AS (2003) The pharmacology of letrozole. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 87 (1). pp. 35-45. ISSN 0960-0760

Dowsett, M. (2003) Preoperative models to evaluate endocrine strategies for breast cancer. CLINICAL CANCER RESEARCH, 9 (1). 502S-510S. ISSN 1078-0432

Dowsett M, Ellis MJ (2003) Role of biologic markers in patient selection and application to disease prevention. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 26 (4). S34-S39. ISSN 0277-3732

Allred DC, Baum M, Buzdar AU, Carlson RS, Dowsett M, Elledge RM, Gradishar WJ, Grana G, Howell A, Mamounas EP (2003) A roundtable discussion of aromatase inhibitors as therapy for breast cancer. THE BREAST JOURNAL, 9 (3). pp. 213-222. ISSN 1075-122X

Simpson, E. R., Dowsett, M. (2002) Aromatase and its inhibitors: significance for breast cancer therapy. RECENT PROGRESS IN HORMONE RESEARCH, 57 . pp. 317-338. ISSN 0079-9963

Davies, G., Martin, L. A., Sacks, N., Dowsett, M. (2002) Cyclooxygenase-2 (COX-2), aromatase and breast cancer: a possible role for COX-2 inhibitors in breast cancer chemoprevention. ANNALS OF ONCOLOGY, 13 (5). pp. 669-678. ISSN 0923-7534

Sotiriou, C., Powles, T. J., Dowsett, M., Jazaeri, A. A., Feldman, A. L., Assersohn, L., Gadisetti, C., Libutti, S. K., Liu, E. T. (2002) Gene expression profiles derived from fine needle aspiration correlate with response to systemic chemotherapy in breast cancer. BREAST CANCER RESEARCH, 4 (3). ISSN 1465-5411

Parton, M., Dowsett, M., Smith, I. (2001) Studies of apoptosis in breast cancer. BRITISH MEDICAL JOURNAL, 322 (7301). pp. 1528-1538. ISSN 0007-1447