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Hammond, M. E. H., Hayes, D. F., Dowsett, M., Allred, D. C., Hagerty, K. L., Badve, S., Fitzgibbons, P. L., Francis, G., Goldstein, N. S., Hayes, M., Hicks, D. G., Lester, S., Love, R., Mangu, P. B., McShane, L., Miller, K., Osborne, C. K., Paik, S., Perlmutter, J., Rhodes, A., Sasano, H., Schwartz, J. N., Sweep, F. C. G., Taube, S., Torlakovic, E. E., Valenstein, P., Viale, G., Visscher, D., Wheeler, T., Williams, R. B., Wittliff, J. L., Wolff, A. C. (2010) American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for Immunohistochemical Testing of Estrogen and Progesterone Receptors in Breast Cancer. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 134 (6). pp. 907-922. ISSN 0003-9985

Hammond, M. E. H., Hayes, D. F., Dowsett, M., Allred, D. C., Hagerty, K. L., Badve, S., Fitzgibbons, P. L., Francis, G., Goldstein, N. S., Hayes, M., Hicks, D. G., Lester, S., Love, R., Mangu, P. B., McShane, L., Miller, K., Osborne, C. K., Paik, S., Perlmutter, J., Rhodes, A., Sasano, H., Schwartz, J. N., Sweep, F. C. G., Taube, S., Torlakovic, E. E., Valenstein, P., Viale, G., Visscher, D., Wheeler, T., Williams, R. B., Wittliff, J. L., Wolff, A. C. (2010) American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for Immunohistochemical Testing of Estrogen and Progesterone Receptors in Breast Cancer (Unabridged Version). ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 134 (7). E48-E72. ISSN 0003-9985

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Freedman, O. C., Amir, E., Hanna, W., Kahn, H., O'Malley, F., Dranitsaris, G., Cole, D. E. C., Verma, S., Folkerd, E., Dowsett, M., Clemons, M. (2010) A randomized trial exploring the biomarker effects of neoadjuvant sequential treatment with exemestane and anastrozole in post-menopausal women with hormone receptor-positive breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 119 (1). pp. 155-161. ISSN 0167-6806

Jones, R. L., Salter, J., A'Hern, R., Nerurkar, A., Parton, M., Reis-Filho, J. S., Smith, I. E., Dowsett, M. (2010) Relationship between oestrogen receptor status and proliferation in predicting response and long-term outcome to neoadjuvant chemotherapy for breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 119 (2). pp. 315-323. ISSN 0167-6806

Dunbier, A. K., Anderson, H., Ghazoui, Z., Folkerd, E. J., A'Hern, R., Crowder, R. J., Hoog, J., Smith, I. E., Osin, P., Nerurkar, A., Parker, J. S., Perou, C. M., Ellis, M. J., Dowsett, M. (2010) Relationship Between Plasma Estradiol Levels and Estrogen-Responsive Gene Expression in Estrogen Receptor-Positive Breast Cancer in Postmenopausal Women. JOURNAL OF CLINICAL ONCOLOGY, 28 (7). pp. 1161-1167. ISSN 0732-183X

Huijbers, I. J., Iravani, M., Popov, S., Robertson, D., Al-Sarraj, S., Jones, C., Isacke, C. M. (2010) A Role for Fibrillar Collagen Deposition and the Collagen Internalization Receptor Endo180 in Glioma Invasion. PLOS ONE, 5 (3). ISSN 1932-6203

Datta, S. R., McQuillin, A., Rizig, M., Blaveri, E., Thirumalai, S., Kalsi, G., Lawrence, J., Bass, N. J., Puri, V., Choudhury, K., Pimm, J., Crombie, C., Fraser, G., Walker, N., Curtis, D., Zvelebil, M., Pereira, A., Kandaswamy, R., St Clair, D., Gurling, H. M. D. (2010) A threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophrenia. MOLECULAR PSYCHIATRY, 15 (6). pp. 615-628. ISSN 1359-4184

Evers, B., Speksnijder, E. N., Schut, E., Ciampricotti, M., Smalley, M. J., Derksen, P. W. B., Jonkers, J., de Visser, K. E. (2010) A tissue reconstitution model to study cancer cell-intrinsic and -extrinsic factors in mammary tumourigenesis. JOURNAL OF PATHOLOGY, 220 (1). pp. 34-44. ISSN 0022-3417

Huser, C. A., Pringle, M. A., Heath, V. J., Bell, A. K., Kendrick, H., Smalley, M. J., Crighton, D., Ryan, K. M., Gusterson, B. A., Stein, T. (2010) TSC-22D1 isoforms have opposing roles in mammary epithelial cell survival. CELL DEATH AND DIFFERENTIATION, 17 (2). pp. 304-315. ISSN 1350-9047

Foulkes, W. D., Reis-Filho, J. S., Narod, S. A. (2010) Tumor size and survival in breast cancer-a reappraisal. NATURE REVIEWS CLINICAL ONCOLOGY, 7 (6). pp. 348-353. ISSN 1759-4774

Ashworth, A., Bernards, R. (2010) Using Functional Genetics to Understand Breast Cancer Biology. COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY, 2 (7). ISSN 1943-0264

Lancashire, L. J., Powe, D. G., Reis-Filho, J. S., Rakha, E., Lemetre, C., Weigelt, B., Abdel-Fatah, T. M., Green, A. R., Mukta, R., Blamey, R., Paish, E. C., Rees, R. C., Ellis, I. O., Ball, G. R. (2010) A validated gene expression profile for detecting clinical outcome in breast cancer using artificial neural networks. BREAST CANCER RESEARCH AND TREATMENT, 120 (1). pp. 83-93. ISSN 0167-6806

Drain, S., Catherwood, M. A., Orr, N., Galligan, L., Rea, I. M., Hodkinson, C., Drake, M. B., Kettle, P. J., Morris, T. C. M., Alexander, H. D. (2009) ABCB1 (MDR1) rs1045642 is associated with increased overall survival in plasma cell myeloma. LEUKEMIA & LYMPHOMA, 50 (4). pp. 566-570. ISSN 1042-8194

O'Riain, C., O'Shea, D. M., Yang, Y., Le Dieu, R., Gribben, J. G., Summers, K., Yeboah-Afari, J., Bhaw-Rosun, L., Fleischmann, C., Mein, C. A., Crook, T., Smith, P., Kelly, G., Rosenwald, A., Ott, G., Campo, E., Rimsza, L. M., Smeland, E. B., Chan, W. C., Johnson, N., Gascoyne, R. D., Reimer, S., Braziel, R. M., Wright, G. W., Staudt, L. M., Lister, T. A., Fitzgibbon, J. (2009) Array-based DNA methylation profiling in follicular lymphoma. LEUKEMIA, 23 (10). pp. 1858-1866. ISSN 0887-6924

Fasquelle, C., Sartelet, A., Li, W., Dive, M., Tamma, N., Michaux, C., Druet, T., Huijbers, I. J., Isacke, C. M., Coppieters, W., Georges, M., Charlier, C. (2009) Balancing Selection of a Frame-Shift Mutation in the MRC2 Gene Accounts for the Outbreak of the Crooked Tail Syndrome in Belgian Blue Cattle. PLOS GENETICS, 5 (9). ISSN 1553-7390

Lord, C. J., Ashworth, A. (2009) Bringing DNA Repair in Tumors into Focus. CLINICAL CANCER RESEARCH, 15 (10). pp. 3241-3243. ISSN 1078-0432

Singh, G., Fletcher, O., Bell, G. S., McLean, A. E., Sander, J. W. (2009) Cancer mortality amongst people with epilepsy: A study of two cohorts with severe and presumed milder epilepsy. EPILEPSY RESEARCH, 83 (2-3). pp. 190-197. ISSN 0920-1211

Bibby, R. A., Tang, C., Faisal, A., Drosopoulos, K., Lubbe, S., Houlston, R., Bayliss, R., Linardopoulos, S. (2009) A Cancer-associated Aurora A Mutant Is Mislocalized and Misregulated Due to Loss of Interaction with TPX2. JOURNAL OF BIOLOGICAL CHEMISTRY, 284 (48). pp. 33177-33184. ISSN 0021-9258

Stephens, P. J., McBride, D. J., Lin, M., Varela, I., Pleasance, E. D., Simpson, J. T., Stebbings, L. A., Leroy, C., Edkins, S., Mudie, L. J., Greenman, C. D., Jia, M., Latimer, C., Teague, J. W., Lau, K. W., Burton, J., Quail, M. A., Swerdlow, H., Churcher, C., Natrajan, R., Sieuwerts, A. M., Martens, J. W. M., Silver, D. P., Langerod, A., Russnes, H. E. G., Foekens, J. A., Reis-Filho, J. S., van't Veer, L., Richardson, A. L., Borresen-Dale, A., Campbell, P. J., Futreal, P. A., Stratton, M. R. (2009) Complex landscapes of somatic rearrangement in human breast cancer genomes. NATURE, 462 (7276). 1005-U60. ISSN 0028-0836

McCarthy, A., Lord, C. J., Savage, K., Grigoriadis, A., Smith, D. P., Weigelt, B., Reis-Filho, J. S., Ashworth, A. (2009) Conditional deletion of the Lkb1 gene in the mouse mammary gland induces tumour formation. JOURNAL OF PATHOLOGY, 219 (3). pp. 306-316. ISSN 0022-3417

Iorns, E., Martens-de Kemp, S. R., Lord, C. J., Ashworth, A. (2009) CRK7 modifies the MAPK pathway and influences the response to endocrine therapy. CARCINOGENESIS, 30 (10). pp. 1696-1701. ISSN 0143-3334

Arnedos, M., Nerurkar, A., Osin, P., A'Hern, R., Smith, I. E., Dowsett, M. (2009) Discordance between core needle biopsy (CNB) and excisional biopsy (EB) for estrogen receptor (ER), progesterone receptor (PgR) and HER2 status in early breast cancer (EBC). ANNALS OF ONCOLOGY, 20 (12). pp. 1948-1952. ISSN 0923-7534

Marchio, C., Lambros, M. B., Gugliotta, P., Di Cantogno, L. V., Botta, C., Pasini, B., Tan, D. S. P., Mackay, A., Fenwick, K., Tamber, N., Bussolati, G., Ashworth, A., Reis-Filho, J. S., Sapino, A. (2009) Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridization and microarray-based CGH analysis. JOURNAL OF PATHOLOGY, 219 (1). pp. 16-24. ISSN 0022-3417

Bax, D. A., Gaspar, N., Little, S. E., Marshall, L., Perryman, L., Regairaz, M., Viana-Pereira, M., Vuononvirta, R., Sharp, S. Y., Reis-Filho, J. S., Stavale, J. N., Al-Sarraj, S., Reis, R. M., Vassal, G., Pearson, A. D. J., Hargrave, D., Ellison, D. W., Workman, P., Jones, C. (2009) EGFRvIII Deletion Mutations in Pediatric High-Grade Glioma and Response to Targeted Therapy in Pediatric Glioma Cell Lines. CLINICAL CANCER RESEARCH, 15 (18). pp. 5753-5761. ISSN 1078-0432

Nicholson, L. J., Smith, P. R., Hiller, L., Szlosarek, P. W., Kimberley, C., Sehouli, J., Koensgen, D., Mustea, A., Schmid, P., Crook, T. (2009) Epigenetic silencing of argininosuccinate synthetase confers resistance to platinum-induced cell death but collateral sensitivity to arginine auxotrophy in ovarian cancer. INTERNATIONAL JOURNAL OF CANCER, 125 (6). pp. 1454-1463. ISSN 0020-7136

Paschos, K., Smith, P., Anderton, E., Middeldorp, J. M., White, R. E., Allday, M. J. (2009) Epstein-Barr Virus Latency in B Cells Leads to Epigenetic Repression and CpG Methylation of the Tumour Suppressor Gene Bim. PLOS PATHOGENS, 5 (6). ISSN 1553-7366

Vuononvirta, R., Sebire, N. J., Messahel, B., Perusinghe, N., Reis-Filho, J. S., Pritchard-Jones, K., Vujanic, G. M., Jones, C. (2009) Expression of Hepatocyte Growth Factor and Its Receptor Met in Wilms' Tumors and Nephrogenic Rests Reflects Their Roles in Kidney Development. CLINICAL CANCER RESEARCH, 15 (8). pp. 2723-2730. ISSN 1078-0432

Martinho, O., Longatto-Filho, A., Lambros, M. B. K., Martins, A., Pinheiro, C., Silva, A., Pardal, F., Amorim, J., Mackay, A., Milanezi, F., Tamber, N., Fenwick, K., Ashworth, A., Reis-Filho, J. S., Lopes, J. M., Reis, R. M. (2009) Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas. BRITISH JOURNAL OF CANCER, 101 (6). pp. 973-982. ISSN 0007-0920

Stone, J., Folkerd, E., Doody, D., Schroen, C., Treloar, S. A., Giles, G. G., Pike, M. C., English, D. R., Southey, M. C., Hopper, J. L., Dowsett, M. (2009) Familial Correlations in Postmenopausal Serum Concentrations of Sex Steroid Hormones and Other Mitogens: A Twins and Sisters Study. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM, 94 (12). pp. 4793-4800. ISSN 0021-972X

Fletcher, O., Johnson, N., Silva, I. D., Kilpivaara, O., Aittomaki, K., Blomqvist, C., Nevanlinna, H., Wasielewski, M., Meijers-Heijerboer, H., Broeks, A., Schmidt, M. K., Van't Veer, L. J., Bremer, M., Dork, T., Chekmariova, E. V., Sokolenko, A. P., Imyanitov, E. N., Hamann, U., Rashid, M. U., Brauch, H., Justenhoven, C., Ashworth, A., Peto, J. (2009) Family History, Genetic Testing, and Clinical Risk Prediction: Pooled Analysis of CHEK2*1100delC in 1,828 Bilateral Breast Cancers and 7,030 Controls. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 18 (1). pp. 230-234. ISSN 1055-9965

Sarrio, D., Palacios, J., Hergueta-Redondo, M., Gomez-Lopez, G., Cano, A., Moreno-Bueno, G. (2009) Functional characterization of E- and P-cadherin in invasive breast cancer cells. BMC CANCER, 9 . ISSN 1471-2407

Geyer, F. C., Decker, T., Reis-Filho, J. S. (2009) Genome-wide expression profiling as a clinical tool. PATHOLOGE, 30 (2). pp. 141-146. ISSN 0172-8113

Westbury, C. B., Reis-Filho, J. S., Dexter, T., Mahler-Araujo, B., Fenwick, K., Iravani, M., Grigoriadis, A., Parry, S., Robertson, D., Mackay, A., Ashworth, A., Yarnold, J. R., Isacke, C. M. (2009) Genome-wide transcriptomic profiling of microdissected human breast tissue reveals differential expression of KIT (c-Kit, CD117) and oestrogen receptor-alpha (ER alpha) in response to therapeutic radiation. JOURNAL OF PATHOLOGY, 219 (1). pp. 131-140. ISSN 0022-3417

Lambros, M. B. K., Tan, D. S. P., Jones, R. L., Vatcheva, R., Savage, K., Tamber, N., Fenwick, K., Mackay, A., Ashworth, A., Reis-Filho, J. S. (2009) Genomic profile of a secretory breast cancer with an ETV6-NTRK3 duplication. JOURNAL OF CLINICAL PATHOLOGY, 62 (7). pp. 604-612. ISSN 0021-9746

Mackay, A., Tamber, N., Fenwick, K., Iravani, M., Grigoriadis, A., Dexter, T., Lord, C. J., Reis-Filho, J. S., Ashworth, A. (2009) A high-resolution integrated analysis of genetic and expression profiles of breast cancer cell lines. BREAST CANCER RESEARCH AND TREATMENT, 118 (3). pp. 481-498. ISSN 0167-6806

Grigoriadis, A., Oliver, G. R., Tanney, A., Kendrick, H., Smalley, M. J., Jat, P., Neville, A. M. (2009) Identification of differentially expressed sense and antisense transcript pairs in breast epithelial tissues. BMC GENOMICS, 10 . ISSN 1471-2164

Packer, L. M., East, P., Reis-Filho, J. S., Marais, R. (2009) Identification of direct transcriptional targets of V600EBRAF/MEK signalling in melanoma. PIGMENT CELL & MELANOMA RESEARCH, 22 (6). pp. 785-798. ISSN 1755-1471

Killock, D. J., Parsons, M., Zarrouk, M., Ameer-Beg, S. M., Ridley, A. J., Haskard, D. O., Zvelebil, M., Ivetic, A. (2009) In Vitro and in Vivo Characterization of Molecular Interactions between Calmodulin, Ezrin/Radixin/Moesin, and L-selectin. JOURNAL OF BIOLOGICAL CHEMISTRY, 284 (13). pp. 8833-8845. ISSN 0021-9258

Fong, P. C., Boss, D. S., Yap, T. A., Tutt, A., Wu, P., Mergui-Roelvink, M., Mortimer, P., Swaisland, H., Lau, A., O'Connor, M. J., Ashworth, A., Carmichael, J., Kaye, S. B., Schellens, J. H. M., De Bono, J. S. (2009) Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers. NEW ENGLAND JOURNAL OF MEDICINE, 361 (2). pp. 123-134. ISSN 0028-4793

Orme, M., Meier, P. (2009) Inhibitor of apoptosis proteins in Drosophila: gatekeepers of death. APOPTOSIS, 14 (8). pp. 950-960. ISSN 1360-8185

Iorns, E., Lord, C. J., Grigoriadis, A., McDonald, S., Fenwick, K., MacKay, A., Mein, C. A., Natrajan, R., Savage, K., Tamber, N., Reis-Filho, J. S., Turner, N. C., Ashworth, A. (2009) Integrated Functional, Gene Expression and Genomic Analysis for the Identification of Cancer Targets. PLOS ONE, 4 (4). ISSN 1932-6203

Shorning, B. Y., Zabkiewicz, J., McCarthy, A., Pearson, H. B., Winton, D. J., Sansom, O. J., Ashworth, A., Clarke, A. R. (2009) Lkb1 Deficiency Alters Goblet and Paneth Cell Differentiation in the Small Intestine. PLOS ONE, 4 (1). ISSN 1932-6203

Natrajan, R., Lambros, M. B. K., Geyer, F. C., Marchio, C., Tan, D. S. P., Vatcheva, R., Shiu, K. K., Hungermann, D., Rodriguez-Pinilla, S. M., Palacios, J., Ashworth, A., Buerger, H., Reis-Filho, J. S. (2009) Loss of 16q in High Grade Breast Cancer is Associated with Estrogen Receptor Status: Evidence for Progression in Tumors with a Luminal Phenotype? GENES CHROMOSOMES & CANCER, 48 (4). pp. 351-365. ISSN 1045-2257

Messaritou, G., East, L., Roghi, C., Isacke, C. M., Yarwood, H. (2009) Membrane type-1 matrix metalloproteinase activity is regulated by the endocytic collagen receptor Endo180. JOURNAL OF CELL SCIENCE, 122 (22). pp. 4042-4048. ISSN 0021-9533

Weigelt, B., Kreike, B., Reis-Filho, J. S. (2009) Metaplastic breast carcinomas are basal-like breast cancers: a genomic profiling analysis. BREAST CANCER RESEARCH AND TREATMENT, 117 (2). pp. 273-280. ISSN 0167-6806

Martin, S. A., McCarthy, A., Barber, L. J., Burgess, D. J., Parry, S., Lord, C. J., Ashworth, A. (2009) Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2. EMBO MOLECULAR MEDICINE, 1 (6-7). pp. 323-337. ISSN 1757-4676

Geyer, F. C., Kushner, Y. B., Lambros, M. B., Natrajan, R., Mackay, A., Tamber, N., Fenwick, K., Purnell, D., Ashworth, A., Walker, R. A., Reis-Filho, J. S. (2009) Microglandular adenosis or microglandular adenoma? A molecular genetic analysis of a case associated with atypia and invasive carcinoma. HISTOPATHOLOGY, 55 (6). pp. 732-743. ISSN 0309-0167

Marchio, C., Iravan, M., Natrajan, R., Lambros, M. B. K., Geyer, F. C., Savage, K., Parry, S., Tamber, N., Fenwick, K., Mackay, A., Schmitt, F. C., Bussolati, G., Ellis, I., Ashworth, A., Sapino, A., Reis-Filho, J. S. (2009) Mixed micropapillary-ductal carcinomas of the breast: a genomic and immunohistochemical analysis of morphologically distinct components. JOURNAL OF PATHOLOGY, 218 (3). pp. 301-315. ISSN 0022-3417

Richardson, C. J., Gao, Q., Mitsopoulous, C., Zvelebil, M., Pearl, L. H., Pearl, F. M. G. (2009) MoKCa database - mutations of kinases in cancer. NUCLEIC ACIDS RESEARCH, 37 (Database Issue). D824-D831. ISSN 0305-1048

Weigelt, B., Geyer, F. C., Horlings, H. M., Kreike, B., Halfwerk, H., Reis-Filho, J. S. (2009) Mucinous and neuroendocrine breast carcinomas are transcriptionally distinct from invasive ductal carcinomas of no special type. MODERN PATHOLOGY, 22 (11). pp. 1401-1414. ISSN 0893-3952

Reis-Filho, J. S. (2009) Next-generation sequencing. BREAST CANCER RESEARCH, 11 (Suppl. 3). ISSN 1465-5411

Dhomen, N., Reis-Filho, J. S., Dias, S. D., Hayward, R., Savage, K., Delmas, V., Larue, L., Pritchard, C., Marais, R. (2009) Oncogenic Braf Induces Melanocyte Senescence and Melanoma in Mice. CANCER CELL, 15 (4). pp. 294-303. ISSN 1535-6108

Iorns, E., Lord, C. J., Ashworth, A. (2009) Parallel RNAi and compound screens identify the PDK1 pathway as a target for tamoxifen sensitization. BIOCHEMICAL JOURNAL, 417 (Part 1). pp. 361-370. ISSN 0264-6021

Liu, T., Sims, D., Baum, B. (2009) Parallel RNAi screens across different cell lines identify generic and cell type-specific regulators of actin organization and cell morphology. GENOME BIOLOGY, 10 (3). ISSN 1474-760X

Tan, D. S. P., Lambros, M. B. K., Rayter, S., Natrajan, R., Vatcheva, R., Gao, Q., Marchio, C., Geyer, F. C., Savage, K., Parry, S., Fenwick, K., Tamber, N., Mackay, A., Dexter, T., Jameson, C., McCluggage, W. G., Williams, A., Graham, A., Faratian, D., El-Bahrawy, M., Paige, A. J., Gabra, H., Gore, M. E., Zvelebil, M., Lord, C. J., Kaye, S. B., Ashworth, A., Reis-Filho, J. S. (2009) PPM1D Is a Potential Therapeutic Target in Ovarian Clear Cell Carcinomas. CLINICAL CANCER RESEARCH, 15 (7). pp. 2269-2280. ISSN 1078-0432

Britt, K. L., Kendrick, H., Regan, J. L., Molyneux, G., Magnay, F. A., Ashworth, A., Smalley, M. J. (2009) Pregnancy in the mature adult mouse does not alter the proportion of mammary epithelial stem/progenitor cells. BREAST CANCER RESEARCH, 11 (2). ISSN 1465-5411

Walker, K., Fletcher, O., Johnson, N., Coupland, B., McCormack, V. A., Folkerd, E., Gibson, L., Hillier, S. G., Holly, J. M., Moss, S., Dowsett, M., Peto, J., Silva, I. S. (2009) Premenopausal Mammographic Density in Relation to Cyclic Variations in Endogenous Sex Hormone Levels, Prolactin, and Insulin-like Growth Factors. CANCER RESEARCH, 69 (16). pp. 6490-6499. ISSN 0008-5472

Jones, R. L., Salter, J., A'Hern, R., Nerurkar, A., Parton, M., Reis-Filho, J. S., Smith, I. E., Dowsett, M. (2009) The prognostic significance of Ki67 before and after neoadjuvant chemotherapy in breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 116 (1). pp. 53-68. ISSN 0167-6806

Shah, R., Smith, P., Purdie, C., Quinlan, P., Baker, L., Aman, P., Thompson, A. M., Crook, T. (2009) The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer. BRITISH JOURNAL OF CANCER, 100 (10). pp. 1687-1696. ISSN 0007-0920

Rocha, R. M., Nunes, C. B., Sanches, F. S. F., Rocha, G. F. S., de Oliveira, F. N., Reis-Filho, J. S., Lambros, M. B., Gobbi, H. (2009) RABBIT ANTIBODIES FOR HORMONE RECEPTORS AND HER2 EVALUATION IN BREAST CANCER. REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, 55 (2). pp. 163-168. ISSN 0104-4230

Hoffman, H. E., Jiraskova, J., Ingr, M., Zvelebil, M., Konvalinka, J. (2009) Recombinant human serine racemase: Enzymologic characterization and comparison with its mouse ortholog. PROTEIN EXPRESSION AND PURIFICATION, 63 (1). pp. 62-67. ISSN 1046-5928

Milne, R. L., Benitez, J., Nevanlinna, H., Heikkinen, T., Aittomaki, K., Blomqvist, C., Ignacio Arias, J., Pilar Zamora, M., Burwinkel, B., Bartram, C. R., Meindl, A., Schmutzler, R. K., Cox, A., Brock, I., Elliott, G., Reed, M. W. R., Southey, M. C., Smith, L., Spurdle, A. B., Hopper, J. L., Couch, F. J., Olson, J. E., Wang, X., Fredericksen, Z., Schuermann, P., Bremer, M., Hillemanns, P., Doerk, T., Devilee, P., Van Asperen, C. J., Tollenaar, R. A. E. M., Seynaeve, C., Hall, P., Czene, K., Liu, J., Li, Y., Ahmed, S., Dunning, A. M., Maranian, M., Pharoah, P. D. P., Chenevix-Trench, G., Beesley, J., Bogdanova, N. V., Antonenkova, N. N., Zalutsky, I. V., Anton-Culver, H., Ziogas, A., Brauch, H., Justenhoven, C., Ko, Y., Haas, S., Fasching, P. A., Strick, R., Ekici, A. B., Beckmann, M. W., Giles, G. G., Severi, G., Baglietto, L., English, D. R., Fletcher, O., Johnson, N., Silva, I., Peto, J., Turnbull, C., Hines, S., Renwick, A., Rahman, N., Nordestgaard, B. G., Bojesen, S. E., Flyger, H., Kang, D., Yoo, K., Noh, D., Mannermaa, A., Kataja, V., Kosma, V., Garcia-Closas, M., Chanock, S., Lissowska, J., Brinton, L. A., Chang-Claude, J., Wang-Gohrke, S., Shen, C., Wang, H., Yu, J., Chen, S., Bermisheva, M., Nikolaeva, T., Khusnutdinova, E., Humphreys, M. K., Morrison, J., Platte, R., Easton, D. F., KConFab Investigators, [Group Author], AOCS Grp, [Group Author], Breast Canc Assoc Consortium, [Group Author] (2009) Risk of Estrogen Receptor-Positive and -Negative Breast Cancer and Single-Nucleotide Polymorphism 2q35-rs13387042. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 101 (14). pp. 1012-1018. ISSN 0027-8874

Lord, C. J., Martin, S. A., Ashworth, A. (2009) RNA interference screening demystified. JOURNAL OF CLINICAL PATHOLOGY, 62 (3). pp. 195-200. ISSN 0021-9746

Drury, S., Anderson, H., Dowsett, M. (2009) Selection of Reference Genes for Normalization of qRT-PCR Data Derived From FFPE Breast Tumors. DIAGNOSTIC MOLECULAR PATHOLOGY, 18 (2). pp. 103-107. ISSN 1052-9551

Attard, G., Reid, A. H. M., A'Hern, R., Parker, C., Oommen, N. B., Folkerd, E., Messiou, C., Molife, L. R., Maier, G., Thompson, E., Olmos, D., Sinha, R., Lee, G., Dowsett, M., Kaye, S. B., Dearnaley, D., Kheoh, T., Molina, A., de Bono, J. S. (2009) Selective Inhibition of CYP17 With Abiraterone Acetate Is Highly Active in the Treatment of Castration-Resistant Prostate Cancer. JOURNAL OF CLINICAL ONCOLOGY, 27 (23). pp. 3742-3748. ISSN 0732-183X

Ellis, P., Barrett-Lee, P., Johnson, L., Cameron, D., Wardley, A., O'Reilly, S., Verrill, M., Smith, I., Yarnold, J., Coleman, R., Earl, H., Canney, P., Twelves, C., Poole, C., Bloomfield, D., Hopwood, P., Johnston, S., Dowsett, M., Bartlett, J. M. S., Ellis, I., Peckitt, C., Hall, E., Bliss, J. M., TACT Trial Management Grp, [Group Author], TACT Trialists, [Group Author] (2009) Sequential docetaxel as adjuvant chemotherapy for early breast cancer (TACT): an open-label, phase III, randomised controlled trial. LANCET, 373 (9676). pp. 1681-1692. ISSN 0140-6736

McCormack, V. A., Dowsett, M., Folkerd, E., Johnson, N., Palles, C., Coupland, B., Holly, J. M., Vinnicombe, S. J., Perry, N. M., Silva, I. S. (2009) Sex steroids, growth factors and mammographic density: a cross-sectional study of UK postmenopausal Caucasian and Afro-Caribbean women. BREAST CANCER RESEARCH, 11 (3). ISSN 1465-5411

Reynolds, A. R., Hart, I. R., Watson, A. R., Welti, J. C., Silva, R. G., Robinson, S. D., Da Violante, G., Gourlaouen, M., Salih, M., Jones, M. C., Jones, D. T., Saunders, G., Kostourou, V., Perron-Sierra, F., Norman, J. C., Tucker, G. C., Hodivala-Dilke, K. M. (2009) Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors. NATURE MEDICINE, 15 (4). pp. 392-400. ISSN 1078-8956

Oliver, A. W., Swift, S., Lord, C. J., Ashworth, A., Pearl, L. H. (2009) Structural basis for recruitment of BRCA2 by PALB2. EMBO REPORTS, 10 (9). pp. 990-996. ISSN 1469-221X

Mendes-Pereira, A. M., Martin, S. A., Brough, R., McCarthy, A., Taylor, J. R., Kim, J., Waldman, T., Lord, C. J., Ashworth, A. (2009) Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors. EMBO MOLECULAR MEDICINE, 1 (6-7). pp. 315-322. ISSN 1757-4676

McCabe, N., Cerone, M. A., Ohishi, T., Seimiya, H., Lord, C. J., Ashworth, A. (2009) Targeting Tankyrase 1 as a therapeutic strategy for BRCA-associated cancer. ONCOGENE, 28 (11). pp. 1465-1470. ISSN 0950-9232

Natrajan, R., Lambros, M. B., Rodriguez-Pinilla, S. M., Moreno-Bueno, G., Tan, D. S. P., Marchio, C., Vatcheva, R., Rayter, S., Mahler-Araujo, B., Fulford, L. G., Hungermann, D., Mackay, A., Grigoriadis, A., Fenwick, K., Tamber, N., Hardisson, D., Tutt, A., Palacios, J., Lord, C. J., Buerger, H., Ashworth, A., Reis-Filho, J. S. (2009) Tiling Path Genomic Profiling of Grade 3 Invasive Ductal Breast Cancers. CLINICAL CANCER RESEARCH, 15 (8). pp. 2711-2722. ISSN 1078-0432

Rakha, E. A., Elsheikh, S. E., Aleskandarany, M. A., Habashi, H. O., Green, A. R., Powe, D. G., El-Sayed, M. E., Benhasouna, A., Brunet, J. S., Akslen, L. A., Evans, A. J., Blamey, R., Reis-Filho, J. S., Foulkes, W. D., Ellis, I. O. (2009) Triple-Negative Breast Cancer: Distinguishing between Basal and Nonbasal Subtypes. CLINICAL CANCER RESEARCH, 15 (7). pp. 2302-2310. ISSN 1078-0432

Rajan, N., Langtry, J. A. A., Ashworth, A., Roberts, C., Chapman, P., Burn, J., Trainer, A. H. (2009) Tumor Mapping in 2 Large Multigenerational Families With CYLD Mutations Implications for Disease Management and Tumor Induction. ARCHIVES OF DERMATOLOGY, 145 (11). pp. 1277-1284. ISSN 0003-987X

Erturk-Hasdemir, D., Broemer, M., Leulier, F., Lane, W. S., Paquette, N., Hwang, D., Kim, C., Stoven, S., Meier, P., Silverman, N. (2009) Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106 (24). pp. 9779-9784. ISSN 0027-8424

Banerjee, S., Zvelebil, M., Furet, P., Mueller-Vieira, U., Evans, D. B., Dowsett, M., Martin, L. A. (2009) The Vascular Endothelial Growth Factor Receptor Inhibitor PTK787/ZK222584 Inhibits Aromatase. CANCER RESEARCH, 69 (11). pp. 4716-4723. ISSN 0008-5472

Dowsett, M., A'Hern, R., Salter, J., Zabaglo, L., Smith, I. E. (2009) Who would have thought a single Ki67 measurement would predict long-term outcome? BREAST CANCER RESEARCH, 11 (Suppl. 3). ISSN 1465-5411

Cariati, M., Naderi, A., Brown, J. P., Smalley, M. J., Pinder, S. E., Caldas, C., Purushotham, A. D. (2008) Alpha-6 integrin is necessary for the tumourigenicity of a stem cell-like subpopulation within the MCF7 breast cancer cell line. INTERNATIONAL JOURNAL OF CANCER, 122 (2). pp. 298-304. ISSN 0020-7136

Viana-Pereira, M., Lopes, J. M., Little, S., Milanezi, F., Basto, D., Pardal, F., Jones, C., Reis-Filho, R. M. (2008) Analysis of EGFR overexpression, EGFR gene amplification and the EGFRvIII mutation in Portuguese high-grade gliomas. ANTICANCER RESEARCH, 28 (2A). pp. 913-920. ISSN 0250-7005

Fletcher, O., Johnson, N., Gibson, L., Coupland, B., Fraser, A., Leonard, A., Silva, I. D., Ashworth, A., Houlston, R., Peto, J. (2008) Association of genetic variants at 8q24 with breast cancer risk. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 17 (3). pp. 702-705. ISSN 1055-9965

Tutt, A., Ashworth, A. (2008) Can genetic testing guide treatment in breast cancer? EUROPEAN JOURNAL OF CANCER, 44 (18). pp. 2774-2780. ISSN 0959-8049

Elsheikh, S. E., Green, A. R., Rakha, E. A., Samaka, R. M., Ammar, A. A., Powe, D., Reis-Filho, J. S., Ellis, I. O. (2008) Caveolin 1 and caveolin 2 are associated with breast cancer basal-like and triple-negative immunophenotype. BRITISH JOURNAL OF CANCER, 99 (2). pp. 327-334. ISSN 0007-0920

Elsheikh, S., Green, A. R., Aleskandarany, M. A., Grainge, M., Paish, C. E., Lambros, M. B. K., Reis, J. S., Ellis, I. O. (2008) CCND1 amplification and cyclin D1 expression in breast cancer and their relation with proteomic subgroups and patient outcome. BREAST CANCER RESEARCH AND TREATMENT, 109 (2). pp. 325-335. ISSN 0167-6806

Rudenko, H. C., Else, M., Dearden, C., Brito-Babapulle, V., Jones, C., Dexter, T., Fenwick, K., Mackay, A., Ashworth, A., Matutes, E., Gonzalez, D., Catovsky, D., Morgan, G. J. (2008) Characterising the TP53-deleted subgroup of chronic lymphocytic leukemia: an analysis of additional cytogenetic abnormalities detected by interphase fluorescence in situ hybridisation and array-based comparative genomic hybridisation. LEUKEMIA & LYMPHOMA, 49 (10). pp. 1879-1886. ISSN 1042-8194

Rayter, S., Elliott, R., Travers, J., Rowlands, M. G., Richardson, T. B., Boxall, K., Jones, K., Linardopoulos, S., Workman, P., Aherne, W., Lord, C. J., Ashworth, A. (2008) A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D. ONCOGENE, 27 (8). pp. 1036-1044. ISSN 0950-9232

Nunes, C. B., Rocha, R. M., Reis-Filho, J. S., Lambros, M. B., Rocha, G. F. S., Sanches, F. S. F., Oliveira, F. N., Gobbi, H. (2008) Comparative analysis of six different antibodies against Her2 including the novel rabbit monoclonal antibody (SP3) and chromogenic in situ hybridisation in breast carcinomas. JOURNAL OF CLINICAL PATHOLOGY, 61 (8). pp. 934-938. ISSN 0021-9746

Natrajan, R., Warren, W., Messahel, B., Reis-Filho, J. S., Brundler, M. A., Dome, J. S., Grundy, P. E., Vujanic, G., Pritchard-Jones, K., Jones, C. (2008) Complex patterns of chromosome 9 alterations including the p16(INK4a) locus in Wilms tumours. JOURNAL OF CLINICAL PATHOLOGY, 61 (1). pp. 95-102. ISSN 0021-9746

Lord, C. J., Iorns, E., Ashworth, A. (2008) Dissecting resistance to endocrine therapy in breast cancer. CELL CYCLE, 7 (13). pp. 1895-1898. ISSN 1538-4101

Savage, K., Leung, S., Todd, S. K., Brown, L. A., Jones, R. L., Robertson, D., James, M., Parry, S., Pinilla, S. M. R., Huntsman, D., Reis-Filho, J. S. (2008) Distribution and significance of caveolin 2 expression in normal breast and invasive breast cancer: an immunofluorescence and immunohistochemical analysis. BREAST CANCER RESEARCH AND TREATMENT, 110 (2). pp. 245-256. ISSN 0167-6806

Wansbury, O., Panchal, H., James, M., Parry, S., Ashworth, A., Howard, B. (2008) Dynamic expression of erbb pathway members during early mammary gland morphogenesis. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 128 (4). pp. 1009-1021. ISSN 0022-202X

Williams, N., [ATAC Trialists Group (includes Mitch Dowsett)] (2008) Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial. LANCET ONCOLOGY, 9 (1). pp. 45-53. ISSN 1470-2045

Dowsett, M., Dunbier, A. K. (2008) Emerging Biomarkers and New Understanding of Traditional Markers in Personalized Therapy for Breast Cancer. CLINICAL CANCER RESEARCH, 14 (24). pp. 8019-8026. ISSN 1078-0432

Simonavicius, N., Robertson, D., Bax, D. A., Jones, C., Huijbers, I. J., Isacke, C. M. (2008) Endosialin (CD248) is a marker of tumor-associated pericytes in high-grade glioma. MODERN PATHOLOGY, 21 (3). pp. 308-315. ISSN 0893-3952

Virgintino, D., Errede, M., Girolamo, F., Capobianco, C., Robertson, D., Vimercati, A., Serio, G., Di Benedetto, A., Yonekawa, Y., Frei, K., Roncali, L. (2008) Fetal blood-brain barrier p-glycoprotein contributes to brain protection during human development. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 67 (1). pp. 50-61. ISSN 0022-3069

Bardet, P. L., Kolahgar, G., Mynett, A., Miguel-Aliaga, I., Briscoe, J., Meier, P., Vincent, J. P. (2008) A fluorescent reporter of caspase activity for live imaging. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 105 (37). pp. 13901-13905. ISSN 0027-8424

Thorat, M. A., Marchio, C., Morimiya, A., Savage, K., Nakshatri, H., Reis-Filho, J. S., Badve, S. (2008) Forkhead box A1 expression in breast cancer is associated with luminal subtype and good prognosis. JOURNAL OF CLINICAL PATHOLOGY, 61 (3). pp. 327-332. ISSN 0021-9746

Brough, R., Wei, D., Leulier, S., Lord, C. J., Rong, Y. S., Ashworth, A. (2008) Functional analysis of drosophila melanogaster BRCA2 in DNA repair. DNA REPAIR, 7 (1). pp. 10-19. ISSN 1568-7864

Arriola, E., Marchio, C., Tan, D. S., Drury, S. C., Lambros, M. B., Natrajan, R., Rodriguez-Pinilla, S. M., Mackay, A., Tamber, N., Fenwick, K., Jones, C., Dowsett, M., Ashworth, A., Reis-Filho, J. S. (2008) Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines. LABORATORY INVESTIGATION, 88 (5). pp. 491-503. ISSN 0023-6837

Marchio, C., Iravani, M., Natrajan, R., Lambros, M. B., Savage, K., Tamber, N., Fenwick, K., Mackay, A., Senetta, R., Di Palma, S., Schmitt, F. C., Bussolati, G., Ellis, I. O., Ashworth, A., Sapino, A., Reis-Filho, J. S. (2008) Genomic and immunophenotypical characterization of pure micropapillary carcinomas of the breast. JOURNAL OF PATHOLOGY, 215 (4). pp. 398-410. ISSN 0022-3417

Marchio, C., Natrajan, R., Shiu, K. K., Lambros, M. B. K., Rodriguez-Pinilla, S. M., Tan, D. S. P., Lord, C. J., Hungermann, D., Fenwick, K., Tamber, N., Mackay, A., Palacios, J., Sapino, A., Buerger, H., Ashworth, A., Reis-Filho, J. S. (2008) The genomic profile of HER2-amplified breast cancers: the influence of ER status. JOURNAL OF PATHOLOGY, 216 (4). pp. 399-407. ISSN 0022-3417

Lo, A. S. Y., Taylor, J. R., Farzaneh, F., Kemeny, D. M., Dibb, N. J., Maher, J. (2008) Harnessing the tumour-derived cytokine, CSF-1, to co-stimulate T-cell growth and activation. MOLECULAR IMMUNOLOGY, 45 (5). pp. 1276-1287. ISSN 0161-5890

Lord, C. J., McDonald, S., Swift, S., Turner, N. C., Ashworth, A. (2008) A high-throughput RNA interference screen for DNA repair determinants of PARP inhibitor sensitivity. DNA REPAIR, 7 (12). pp. 2010-2019. ISSN 1568-7864

Melchor, L., Smalley, M. J. (2008) Highway to heaven: mammary gland development and differentiation. BREAST CANCER RESEARCH, 10 (5). ISSN 1465-5411

Gyrd-Hansen, M., Darding, M., Miasari, M., Santoro, M. M., Zender, L., Xue, W., Tenev, T., da Fonseca, P. C. A., Zvelebil, M., Bujnicki, J. M., Lowe, S., Silke, J., Meier, P. (2008) IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappa B as well as cell survival and oncogenesis. NATURE CELL BIOLOGY, 10 (11). 1309-U130. ISSN 1465-7392

Folkes, A. J., Ahmadi, K., Alderton, W. K., Alix, S., Baker, S. J., Box, G., Chuckowree, I. S., Clarke, P. A., Depledge, P., Eccles, S. A., Friedman, L. S., Hayes, A., Hancox, T. C., Kugendradas, A., Lensun, L., Moore, P., Olivero, A. G., Pang, J., Patel, S., Pergl-Wilson, G. H., Raynaud, F. I., Robson, A., Saghir, N., Salphati, L., Sohal, S., Ultsch, M. H., Valenti, M., Wallweber, H. J. A., Wan, N. C., Wiesmann, C., Workman, P., Zhyvoloup, A., Zvelebil, M. J., Shuttleworth, S. J. (2008) The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer. JOURNAL OF MEDICINAL CHEMISTRY, 51 (18). pp. 5522-5532. ISSN 0022-2623

Iorns, E., Turner, N. C., Elliott, R., Syed, N., Garrone, O., Gasco, M., Tutt, A. N. J., Crook, T., Lord, C. J., Ashworth, A. (2008) Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer. CANCER CELL, 13 (2). pp. 91-104. ISSN 1535-6108

Palles, C., Johnson, N., Coupland, B., Taylor, C., Carvajal, J., Holly, J., Fentiman, I. S., Silva, I. D., Ashworth, A., Peto, J., Fletcher, O. (2008) Identification of genetic variants that influence circulating IGF1 levels: a targeted search strategy. HUMAN MOLECULAR GENETICS, 17 (10). pp. 1457-1464. ISSN 0964-6906

Ditzel, M., Broemer, M., Tenev, T., Boiduc, C., Lee, T. V., Rigbolt, K. T. G., Elliot, R., Zvelebil, M., Blagoev, B., Bergmann, A., Meier, P. (2008) Inactivation of Effector Caspases through Nondegradative Polyubiquitylation. MOLECULAR CELL, 32 (4). pp. 540-553. ISSN 1097-2765

Reis-Filho, J. S., Natrajan, R., Vatcheva, R., Lambros, M. B. K., Marcho, C., Mahler-Araujo, B., Paish, C., Hodi, Z., Eusebi, V., Ellis, I. O. (2008) Is acinic cell carcinoma a variant of secretory carcinoma? A FISH study using ETV6 'split apart' probes. HISTOPATHOLOGY, 52 (7). pp. 840-846. ISSN 0309-0167

Pearson, H. B., McCarthy, A., Collins, C. M. P., Ashworth, A., Clarke, A. R. (2008) Lkb1 deficiency causes prostate neoplasia in the mouse. CANCER RESEARCH, 68 (7). pp. 2223-2232. ISSN 0008-5472

Fiegl, H., Jones, A., Hauser-Kronberger, C., Hutarew, G., Reitsamer, R., Jones, R. L., Dowsett, M., Mueller-Holzner, E., Windbichler, G., Daxenbichler, G., Goebel, G., Ensinger, C., Jacobs, I., Widschwendter, M. (2008) Methylated NEUROD1 promoter is a marker for chemosensitivity in breast cancer. CLINICAL CANCER RESEARCH, 14 (11). pp. 3494-3502. ISSN 1078-0432

Simpson, P. T., ReIs-Filho, J. S., Lambros, M. B. K., Jones, C., Steele, D., Mackay, A., Iravani, M., Fenwick, K., Dexter, T., Jones, A., Reid, L., Da Silva, L., Shin, S. J., Hardisson, D., Ashworth, A., Schmitt, F. C., Palacios, J., Lakhani, S. R. (2008) Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas. JOURNAL OF PATHOLOGY, 215 (3). pp. 231-244. ISSN 0022-3417

Abdel-Fatah, T. M. A., Powe, D. G., Hodi, Z., Reis-Filho, J. S., Lee, A. H. S., Ellis, I. O. (2008) Morphologic and molecular evolutionary pathways of low nuclear grade invasive breast cancers and their putative precursor lesions: Further evidence to support the concept of low nuclear grade breast neoplasia family. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 32 (4). pp. 513-523. ISSN 0147-5185

Robertson, D., Savage, K., Reis-Filho, J. S., Isacke, C. M. (2008) Multiple immunofluorescence labelling of formalin-fixed paraffin-embedded (FFPE) tissue. BMC CELL BIOLOGY, 9 . ISSN 1471-2121

Parry, S., Savage, K., Marchio, C., Reis-Filho, J. S. (2008) Nestin is expressed in basal-like and triple negative breast cancers. JOURNAL OF CLINICAL PATHOLOGY, 61 (9). pp. 1045-1050. ISSN 0021-9746

Strizzi, L., Mancino, M., Bianco, C., Raafat, A., Gonzales, M., Booth, B. W., Watanabe, K., Nagaoka, T., Mack, D. L., Howard, B., Callahan, R., Smith, G. H., Salomon, D. S. (2008) Netrin-1 can affect morphogenesis and differentiation of the mouse mammary gland. JOURNAL OF CELLULAR PHYSIOLOGY, 216 (3). pp. 824-834. ISSN 0021-9541

Schwarz, Q., Vieira, J. M., Howard, B., Eickholt, B. J., Ruhrberg, C. (2008) Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells. DEVELOPMENT, 135 (9). pp. 1605-1613. ISSN 0950-1991

Nasri, S., More, H., Graziano, F., Ruzzo, A., Wilson, E., Dunbier, A., McKinney, C., Merriman, T., Guilford, P., Magnani, M., Humar, B. (2008) A novel diffuse gastric cancer susceptibility variant in E-cadherin (CDH1) intron 2: A case control study in an Italian population. BMC CANCER, 8 . ISSN 1471-2407

Towler, M. C., Fogarty, S., Hawley, S. A., Pan, D. A., Martin, D. M. A., Morrice, N. A., McCarthy, A., Galardo, M. N., Meroni, S. B., Cigorraga, S. B., Ashworth, A., Sakamoto, K., Hardie, D. G. (2008) A novel short splice variant of the tumour suppressor LKB1 is required for spermiogenesis. BIOCHEMICAL JOURNAL, 416 (1). pp. 1-14. ISSN 0264-6021

Ashworth, A., Balkwill, F., Bast, R. C., Berek, J. S., Kaye, A., Boyd, J. A., Mills, G., Weinstein, J. N., Woolley, K., Workman, P. (2008) Opportunities and challenges in ovarian cancer research, a perspective from the 11th Ovarian cancer action/HHMT Forum, Lake Como, March 2007. GYNECOLOGIC ONCOLOGY, 108 (3). pp. 652-657. ISSN 0090-8258

Dowsett, M. (2008) Optimizing the implementation of future treatment using surrogate end-points. BREAST CANCER RESEARCH, 10 (Supplement 4). ISSN 1465-5411

Vuononvirta, R., Sebire, N. J., Dallosso, A. R., Reis-Filho, J. S., Williams, R. D., Mackay, A., Fenwick, K., Grigoriadis, A., Ashworth, A., Pritchard-Jones, K., Brown, K. W., Vujanic, G. M., Jones, C. (2008) Perilobar Nephrogenic Rests Are Nonobligate Molecular Genetic Precursor Lesions of Insulin-Like Growth Factor-II-Associated Wilms Tumors. CLINICAL CANCER RESEARCH, 14 (23). pp. 7635-7644. ISSN 1078-0432

Reynolds, C. H., Garwood, C. J., Wray, S., Price, C., Kellie, S., Perera, T., Zvelebil, M., Yang, A., Sheppard, P. W., Varndell, I. M., Hanger, D. P., Anderton, B. H. (2008) Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase C gamma 1, Grb2, and Src family kinases. JOURNAL OF BIOLOGICAL CHEMISTRY, 283 (26). pp. 18177-18186. ISSN 0021-9258

Lhocine, N., Ribeiro, P. S., Buchon, N., Wepf, A., Wilson, R., Tenev, T., Lemaitre, B., Gstaiger, M., Meier, P., Leulier, F. (2008) PIMS modulates immune tolerance by negatively regulating Drosophila innate immune signaling. CELL HOST & MICROBE, 4 (2). pp. 147-158. ISSN 1931-3128

Urruticoechea, A., Aguilar, H., Sole, X., Capella, G., Martin, L. A., Dowsett, M., Germa-Lluch, J. R. (2008) Pre-clinical validation of early molecular markers of sensitivity to aromatase inhibitors in a mouse model of post-menopausal hormone-sensitive breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 109 (3). pp. 463-470. ISSN 0167-6806

Lim, S. L., Smith, P., Syed, N., Coens, C., Wong, H., van der Burg, M., Szlosarek, P., Crook, T., Green, J. A. (2008) Promoter hypermethylation of FANCF and outcome in advanced ovarian cancer. BRITISH JOURNAL OF CANCER, 98 (8). pp. 1452-1456. ISSN 0007-0920

Mahler-Araujo, B., Savage, K., Parry, S., Reis-Filho, J. S. (2008) Reduction of E-cadherin expression is associated with non-lobular breast carcinomas of basal-like and triple negative phenotype. JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY, 61 (5). pp. 615-620. ISSN 1366-8714

Edwards, S. L., Brough, R., Lord, C. J., Natrajan, R., Vatcheva, R., Levine, D. A., Boyd, J., Reis-Filho, J. S., Ashworth, A. (2008) Resistance to therapy caused by intragenic deletion in BRCA2. NATURE, 451 (7182). pp. 1111-1115. ISSN 0028-0836

Howard, B. A. (2008) The role of NRG3 in mammary development. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, 13 (2). pp. 195-203. ISSN 1083-3021

Zvelebil, M. J., Waterfield, M. D., Shuttleworth, S. J. (2008) Structural analysis of PI3-kinase isoforms: Identification of residues enabling selective inhibition by small molecule ATP-competitive inhibitors. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 477 (2). pp. 404-410. ISSN 0003-9861

Komander, D., Lord, C. J., Scheel, H., Swift, S., Hofmann, K., Ashworth, A., Barford, D. (2008) The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module. MOLECULAR CELL, 29 (4). pp. 451-464. ISSN 1097-2765

Turner, N. C., Lord, C. J., Iorns, E., Brough, R., Swift, S., Elliott, R., Rayter, S., Tutt, A. N., Ashworth, A. (2008) A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor. EMBO JOURNAL, 27 (9). pp. 1368-1377. ISSN 0261-4189

Ashworth, A. (2008) A synthetic lethal therapeutic approach: Poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair. JOURNAL OF CLINICAL ONCOLOGY, 26 (22). pp. 3785-3790. ISSN 0732-183X

Tan, D. S. P., Marchio, C., Jones, R. L., Savage, K., Smith, I. E., Dowsett, M., Reis, J. S. (2008) Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients. BREAST CANCER RESEARCH AND TREATMENT, 111 (1). pp. 27-44. ISSN 0167-6806

Anderton, E., Yee, J., Smith, P., Crook, T., White, R. E., Allday, M. J. (2008) Two Epstein-Barr virus (EBV) oncoproteins cooperate to repress expression of the proapoptotic tumour-suppressor Bim: clues to the pathogenesis of Burkitt's lymphoma. ONCOGENE, 27 (4). pp. 421-433. ISSN 0950-9232

Yuan, M., Tomlinson, V., Lara, R., Holliday, D., Chelala, C., Harada, T., Gangeswaran, R., Manson-Bishop, C., Smith, P., Danovi, S. A., Pardo, O., Crook, T., Mein, C. A., Lemoine, N. R., Jones, L. J., Basu, S. (2008) Yes-associated protein (YAP) functions as a tumor suppressor in breast. CELL DEATH AND DIFFERENTIATION, 15 (11). pp. 1752-1759. ISSN 1350-9047

Natrajan, R., Little, S. E., Sodha, N., Reis-Filho, J. S., Mackay, A., Fenwick, K., Ashworth, A., Perlman, E. J., Dome, J. S., Grundy, P. E., Pritchard-Jones, K., Jones. C. (2007) Analysis by array CGH of genomic changes associated with the progression or relapse of Wilms' tumour. JOURNAL OF PATHOLOGY, 211 (1). pp. 52-59. ISSN 0022-3417

Tischkowitz, M., Xia, B., Sabbaghian, N., Reis-Filho, J. S., Hamel, N., Li, G. L., van Beers, E. H., Li, L. L., Khalil, T., Quenneville, L. A., Omeroglu, A., Poll, A., Lepage, P., Wong, N., Nederlof, P. M., Ashworth, A., Tonin, P. N., Narod, S. A., Livingston, D. M., Foulkes, W. D. (2007) Analysis of PALB2/FANCN-associated breast cancer families. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 104 (16). pp. 6788-6793. ISSN 0027-8424

Tenev, T., Ditzel, M., Zachariou, A., Meier, P. (2007) The antiapoptotic activity of insect IAPs requires activation by an evolutionarily conserved mechanism. CELL DEATH AND DIFFERENTIATION, 14 (6). pp. 1191-1201. ISSN 1350-9047

Sun, C. B., Chan, F., Briassouli, P., Linardopoulos, S. (2007) Aurora kinase inhibition downregulates NF-kappa B and sensitises tumour cells to chemotherapeutic agents. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 352 (1). pp. 220-225. ISSN 0006-291X

Linardopoulos, S. (2007) Aurora-A kinase regulates NF-kB activity: lessons from combination studies. JOURNAL OF BUON, 12 (Supplement 1). S67-S70. ISSN 1107-0625

Briassouli, P., Chan, F., Savage, K., Reis-Filho, J. S., Linardopoulos, S. (2007) Aurora-A regulation of nuclear factor-kappa B signaling by phosphorylation of I kappa B alpha. CANCER RESEARCH, 67 (4). pp. 1689-1695. ISSN 0008-5472

Fulford, L. G., Reis-Filho, J. S., Ryder, K., Jones, C., Gillett, C. E., Hanby, A., Easton, D. F., Lakhani, S. R. (2007) Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival. BREAST CANCER RESEARCH, 9 (1). ISSN 1465-5411

Turner, N. C., Reis-Filho, J. S., Russell, A. M., Springall, R. J., Ryder, K., Steele, D., Savage, K., Gillett, C. E., Schmitt, F. C., Ashworth, A., Tutt, A. N. (2007) BRCA1 dysfunction in sporadic basal-like breast cancer. ONCOGENE, 26 (14). pp. 2126-2132. ISSN 0950-9232

Kote-Jarai, Z., Powles, T. J., Mitchell, G., Tidy, A., Ashley, S., Easton, D., Assersohn, L., Sodha, N., Salter, J., Gusterson, B., Dowsett, M., Eeles, R. (2007) BRCA1/BRCA2 mutation status and analysis of cancer family history in participants of the Royal Marsden Hospital tamoxifen chemoprevention trial. CANCER LETTERS, 247 (2). pp. 259-265. ISSN 0304-3835

Jones, C., Rodriguez-Pinilla, M., Lambros, M., Bax, D., Messahel, B., Vujanic, G. M., Reis-Filho, J. S., Pritchard-Jones, K. (2007) c-KIT overexpression, without gene amplification and mutation, in paediatric renal tumours. JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY, 60 (11). pp. 1226-1231. ISSN 1366-8714

Savage, K., Lambros, M. B. K., Robertson, D., Jones, R. L., Jones, C., Mackay, A., James, M., Hornick, J. L., Pereira, E. M., Milanezi, F., Fletcher, C. D. M., Schmitt, F. C., Ashworth, A., Reis-Filho, J. S. (2007) Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: A morphologic, ultrastructural, immunohistochemical, and in situ hybridization analysis. CLINICAL CANCER RESEARCH, 13 (1). pp. 90-101. ISSN 1078-0432

Lax, S., Hou, T. Z., Jenkinson, E., Salmon, M., MacFadyen, J. R., Isacke, C. M., Anderson, G., Cunningham, A. F., Buckley, C. D. (2007) CD248/endosialin is dynamically expressed on a subset of stromal cells during lymphold tissue development, splenic remodeling and repair. FEBS LETTERS, 581 (18). pp. 3550-3556. ISSN 0014-5793

Wienke, D., Davies, G. C., Johnson, D. A., Sturge, J., Lambros, M. B. K., Savage, K., Elsheikh, S. E., Green, A. R., Ellis, I. O., Robertson, D., Reis-Filho, J. S., Isacke, C. M. (2007) The collagen receptor endo180 (CD280) is expressed on basal-like breast tumor cells and promotes tumor growth in vivo. CANCER RESEARCH, 67 (21). pp. 10230-10240. ISSN 0008-5472

Cox, A., Dunning, A. M., Garcia-Closas, M., Balasubramanian, S., Reed, M. W. R., Pooley, K. A., Scollen, S., Baynes, C., Ponder, B. A. J., Chanock, S., Lissowska, J., Brinton, L., Peplonska, B., Southey, M. C., Hopper, J. L., McCredie, M. R. E., Giles, G. G., Fletcher, O., Johnson, N., Silva, I. D., Gibson, L., Bojesen, S. E., Nordestgaard, B. G., Axelsson, C. K., Torres, D., Hamann, U., Justenhoven, C., Brauch, H., Chang-Claude, J., Kropp, S., Risch, A., Wang-Gohrke, S., Schurmann, P., Bogdanova, N., Dork, T., Fagerholm, R., Aaltonen, K., Blomqvist, C., Nevanlinna, H., Seal, S., Renwick, A., Stratton, M. R., Rahman, N., Sangrajrang, S., Hughes, D., Odefrey, F., Brennan, P., Spurdle, A. B., Chenevix-Trench, G., Beesley, J., Mannermaa, A., Hartikainen, J., Kataja, V., Kosma, V. M., Couch, F. J., Olson, J. E., Goode, E. L., Broeks, A., Schmidt, M. K., Hogervorst, F. B. L., Van't Veer, L. J., Kang, D., Yoo, K. Y., Noh, D. Y., Ahn, S. H., Wedren, S., Hall, P., Low, Y. L., Liu, J. J., Milne, R. L., Ribas, G., Gonzalez-Neira, A., Benitez, J., Sigurdson, A. J., Stredrick, D. L., Alexander, B. H., Struewing, J. P., Pharoah, P. D. P., Easton, D. F., Kathleen Cunningham Fdn Consortium, [Group Author], Breast Canc Assoc Consortium, [Group Author] (2007) A common coding variant in CASP8 is associated with breast cancer risk. NATURE GENETICS, 39 (3). pp. 352-358. ISSN 1061-4036

Noble, J. L., Dua, R. S., Coulton, G. R., Isacke, C. M., Gui, G. P. H. (2007) A comparative proteinomic analysis of nipple aspiration fluid from healthy women and women with breast cancer. EUROPEAN JOURNAL OF CANCER, 43 (16). pp. 2315-2320. ISSN 0959-8049

Johnson, N., Fletcher, O., Palles, C., Rudd, M., Webb, E., Sellick, G., Silva, I. D. S., McCormack, V., Gibson, L., Fraser, A., Leonard, A., Gilham, C., Tavtigian, S. V., Ashworth, A., Houlston, R., Peto, J. (2007) Counting potentially functional variants in BRCA1, BRCA2 and ATM predicts breast cancer susceptibility. HUMAN MOLECULAR GENETICS, 16 (9). pp. 1051-1057. ISSN 0964-6906

Whittaker, S. R., Poele, R. H. T., Chan, F., Linardopoulos, S., Walton, M. I., Garrett, M. D., Workman, P. (2007) The cyclin-dependent kinase inhibitor seliciclib (Rroscovitine; CYC202) decreases the expression of mitotic control genes and prevents entry into mitosis. CELL CYCLE, 6 (24). pp. 3114-3131. ISSN 1538-4101

Amary, M. F. C., Berisha, F., Bernardi, F. D., Herbert, A., James, M., Reis-Filho, J. S., Fisher, C., Nicholson, A. G., Tirabosco, R., Diss, T. C., Flanagan, A. M. (2007) Detection of SS18-SSX fusion transcripts in formalin-fixed paraffin-embedded neoplasms: analysis of conventional RT-PCR, qRT-PCR and dual color FISH as diagnostic tools for synovial sarcoma. MODERN PATHOLOGY, 20 (4). pp. 482-496. ISSN 0893-3952

Ribeiro, P. S., Kuranaga, E., Tenev, T., Leulier, F., Miura, M., Meier, P. (2007) DIAP2 functions as a mechanism-based regulator of drICE that contributes to the caspase activity threshold in living cells. JOURNAL OF CELL BIOLOGY, 179 (7). pp. 1467-1480. ISSN 0021-9525

Sleeman, K. E., Kendrick, H., Robertson, D., Isacke, C. M., Ashworth, A., Smalley, M. J. (2007) Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland. JOURNAL OF CELL BIOLOGY, 176 (1). pp. 19-26. ISSN 0021-9525

Schmidt, M. K., Reincke, S., Broeks, A., Braaf, L. M., Hogervorst, F. B. L., Tollenaar, Raem, Johnson, N., Fletcher, O., Peto, J., Tommiska, J., Blomqvist, C., Nevanlinna, H. A., Healey, C. S., Dunning, A. M., Pharoah, P. D. P., Easton, D. F., Doork, T., Van't Veer, L. J., Breast Cancer Ass Consortium, [Group Author] (2007) Do MDM2 SNP309 and TP53 R72P interact in breast cancer susceptibility? A large pooled series from the breast cancer association consortium. CANCER RESEARCH, 67 (19). pp. 9584-9590. ISSN 0008-5472

Jones, M. E., Folkerd, E. J., Doody, D. A., Iqbal, J., Dowsett, M., Ashworth, A., Swerdlow, A. J. (2007) Effect of delays in processing blood samples on measured endogenous plasma sex hormone levels in women. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 16 (6). pp. 1136-1139. ISSN 1055-9965

MacFadyen, J., Savage, K., Wienke, D., Isacke, C. M. (2007) Endosialin is expressed on stromal fibroblasts and CNS pericytes in mouse embryos and is downregulated during development. GENE EXPRESSION PATTERNS, 7 (3). pp. 363-369. ISSN 1567-133X

Smith, P., Nicholson, L. J., Syed, N., Payne, A., Hiller, L., Garrone, O., Occelli, M., Gasco, M., Crook, T. (2007) Epigenetic inactivation implies independent functions for insulin-like growth factor binding protein (IGFBP) - Related protein 1 and the related IGFBPL1 in inhibiting breast cancer phenotypes. CLINICAL CANCER RESEARCH, 13 (14). pp. 4061-4068. ISSN 1078-0432

Arriola, E., Lambros, M. B. K., Jones, C., Dexter, T., Mackay, A., Tan, D. S. P., Tamber, N., Fenwick, K., Ashworth, A., Dowsett, M., Reis-Filho, J. S. (2007) Evaluation of Phi29-based whole-genome amplification for microarray-based comparative genomic hybridisation. LABORATORY INVESTIGATION, 87 (1). pp. 75-83. ISSN 0023-6837

Lee, A. H. S., Paish, E. C., Marchio, C., Sapino, A., Schmitt, F. C., Ellis, I. O., Reis-Filho, J. S. (2007) The expression of Wilms' tumour-1 and Ca125 in invasive micropapillary carcinoma of the breast. HISTOPATHOLOGY, 51 (6). pp. 824-828. ISSN 0309-0167

Elsheikh, S. E., Green, A. R., Lambros, M. B. K., Turner, N. C., Grainge, M. J., Powe, D., Ellis, I. O., Reis-Filho, J. S. (2007) FGFR1 amplification in breast carcinomas: a chromogenic in situ hybridisation analysis. BREAST CANCER RESEARCH, 9 (2). R23-R23. ISSN 1465-5411

Maloney, A., Clarke, P. A., Naaby-Hansen, S., Stein, R., Koopman, J. O., Akpan, A., Yang, A., Zvelebil, M., Cramer, R., Stimson, L., Aherne, W., Banerji, U., Judson, I., Sharp, S., Powers, M., deBilly, E., Salmons, J., Walton, M., Burlingame, A., Waterfield, M., Workman, P. (2007) Gene and protein expression profiling of human ovarian cancer cells treated with the heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin. CANCER RESEARCH, 67 (7). pp. 3239-3253. ISSN 0008-5472

Easton, D. F., Pooley, K. A., Dunning, A. M., Pharoah, P. D. P., Thompson, D., Ballinger, D. G., Struewing, J. P., Morrison, J., Field, H., Luben, R., Wareham, N., Ahmed, S., Healey, C. S., Bowman, R., Meyer, K. B., Haiman, C. A., Kolonel, L. K., Henderson, B. E., Le Marchand, L., Brennan, P., Sangrajrang, S., Gaborieau, V., Stratton M., Rahman, N., Fletcher, O., SEARCH Collaborators, [Group Author], kConFab, [Group Author], AOCS Management Grp, [Group Author] (2007) Genome-wide association study identifies novel breast cancer susceptibility loci. NATURE, 447 (7148). pp. 1087-1093. ISSN 0028-0836

Abdel-Fatah, T. M. A., Powe, D. G., Hodi, Z., Lee, A. H. S., Reis-Filho, J. S., Ellis, I. O. (2007) High frequency of coexistence of columnar cell lesions, lobular neoplasia, and low grade ductal carcinoma in situ with invasive tubular carcinoma and invasive lobular carcinoma. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 31 (3). pp. 417-426. ISSN 0147-5185

Bavetsias, V., Sun, C., Bouloc, N., Reynisson, J., Workman, P., Linardopoulos, S., McDonald, E. (2007) Hit generation and exploration: Imidazo[4,5-b] pyridine derivatives as inhibitors of Aurora kinases. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 17 (23). pp. 6567-6571. ISSN 0960-894X

Westbury, C. B., Pearson, A., Nerurkar, A., Reis-Filho, J. S., Steele, D., Peckitt, C., Sharp, G., Yarnold, J. R. (2007) Hypoxia can be detected in irradiated normal human tissue: a study using the hypoxic marker pimonidazole hydrochloride. BRITISH JOURNAL OF RADIOLOGY, 80 (959). pp. 934-938. ISSN 0007-1285

Esseghir, S., Kennedy, A., Seedhar, P., Nerurkar, A., Poulsom, R., Reis-Filho, J. S., Isacke, C. M. (2007) Identification of NTN4, TRA1, and STC2 as prognostic markers in breast cancer in a screen for signal sequence encoding proteins. CLINICAL CANCER RESEARCH, 13 (11). pp. 3164-3173. ISSN 1078-0432

Nolte-'t Hoen, E. N. M., Almeida, C. R., Cohen, N. R., Nedvetzki, S., Yarwood, H., Davis, D. M. (2007) Increased surveillance of cells in mitosis by human NK cells suggests a novel strategy for limiting tumor growth and viral replication. BLOOD, 109 (2). pp. 670-673. ISSN 0006-4971

Dowsett, M., Goldhirsch, A., Hayes, D. F., Senn, H. J., Wood, W., Viale, G. (2007) International Web-based consultation on priorities for translational breast cancer research. BREAST CANCER RESEARCH, 9 (6). ISSN 1465-5411

Takeda, S., Iwai, A., Nakashima, M., Fujikura, D., Chiba, S., Li, H. M., Uehara, J., Kawaguchi, S., Kaya, M., Nagoya, S., Wada, T., Yuan, J. Y., Rayter, S., Ashworth, A., Reed, J. C., Yamashita, T., Uede, T., Miyazaki, T. (2007) LKB1 is crucial for TRAIL-mediated apoptosis induction in osteosarcoma. ANTICANCER RESEARCH, 27 (2). pp. 761-768. ISSN 0250-7005

Ellis, M. J., Dixon, M., Dowsett, M., Nagarajan, R., Mardis, E. (2007) A luminal breast cancer genome atlas: Progress and barriers. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 106 (1–5). pp. 125-129. ISSN 0960-0760

Sturge, J., Todd, S. K., Kogianni, G., McCarthy, A., Isacke, C. M. (2007) Mannose receptor regulation of macrophage cell migration. JOURNAL OF LEUKOCYTE BIOLOGY, 82 (3). pp. 585-593. ISSN 0741-5400

Pierga, J. Y., Reis-Filho, J. S., Cleator, S. J., Dexter, T., MacKay, A., Simpson, P., Fenwick, K., Iravani, M., Salter, J., Hills, M., Jones, C., Ashworth, A., Smith, I. E., Powles, T., Dowsett, M. (2007) Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapy. BRITISH JOURNAL OF CANCER, 96 (2). pp. 341-351. ISSN 0007-0920

Mackay, A., Urruticoechea, A., Dixon, J. M., Dexter, T., Fenwick, K., Ashworth, A., Drury, S., Larionov, A., Young, O., White, S., Miller, W. R., Evans, D. B., Dowsett, M. (2007) Molecular response to aromatase inhibitor treatment in primary breast cancer. BREAST CANCER RESEARCH, 9 (3). ISSN 1465-5411

McCarthy, A., Savage, K., Gabriel, A., Naceur, C., Reis-Filho, J. S., Ashworth, A. (2007) A mouse model of basal-like breast carcinoma with metaplastic elements. JOURNAL OF PATHOLOGY, 211 (4). pp. 389-398. ISSN 0022-3417

Rodriguez-Pinilla, S. M., Jones, R. L., Lambros, M. B. K., Arriola, E., Savage, K., James, M., Pinder, S. E., Reis-Filho, J. S. (2007) MYC amplification in breast cancer: a chromogenic in situ hybridisation study. JOURNAL OF CLINICAL PATHOLOGY, 60 (9). pp. 1017-1023. ISSN 0021-9746

Pinder, S. E., Reis-Filho, J. S. (2007) Non-operative breast pathology: columnar cell lesions. JOURNAL OF CLINICAL PATHOLOGY, 60 (12). pp. 1307-1312. ISSN 0021-9746

Reis-Filho, J. S., Pinder, S. E. (2007) Non-operative breast pathology: lobular neoplasia. JOURNAL OF CLINICAL PATHOLOGY, 60 (12). pp. 1321-1327. ISSN 0021-9746

Di Palma, S., Lambros, M. B. K., Savage, K., Jones, C., Mackay, A., Dexter, T., Iravani, M., Fenwick, K., Ashworth, A., Reis-Filho, J. S. (2007) Oncocytic change in pleomorphic adenoma: molecular evidence in support of an origin in neoplastic cells. JOURNAL OF CLINICAL PATHOLOGY, 60 (5). pp. 492-499. ISSN 0021-9746

Low, Y. L., Dunning, A. M., Dowsett, M., Folkerd, E., Doody, D., Taylor, J., Bhaniani, A., Luben, R., Khaw, K. T., Wareham, N. J., Bingham, S. A. (2007) Phytoestrogen exposure is associated with circulating sex hormone levels in postmenopausal women and interact with ESR1 and NR1I2 gene variants. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 16 (5). pp. 1009-1016. ISSN 1055-9965

Mantovani, F., Tocco, F., Girardini, J., Smith, P., Gasco, M., Lu, X., Crook, T., Del Sal, G. (2007) The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP. NATURE STRUCTURAL & MOLECULAR BIOLOGY, 14 (10). pp. 912-920. ISSN 1545-9985

Gudmundsdottir, K., Lord, C. J., Ashworth, A. (2007) The proteasome is involved in determining differential utilization of double-strand break repair pathways. ONCOGENE, 26 (54). pp. 7601-7606. ISSN 0950-9232

Noble, J., Dua, R. S., Locke, I., Eeles, R., Gui, G. P. H., Isacke, C. M. (2007) Proteomic analysis of nipple aspirate fluid throughout the menstrual cycle in healthy pre-menopausal women. BREAST CANCER RESEARCH AND TREATMENT, 104 (2). pp. 191-196. ISSN 0167-6806

Plaza-Menacho, I., van der Sluis, T., Hollema, H., Gimm, O., Buys, C., Magee, A. I., Isacke, C. M., Hofstra, R. M. W., Eggen, B. J. L. (2007) Ras/ERK1/2-mediated STAT3 Ser(727) phosphorylation by familial medullary thyroid carcinoma-associated RET mutants induces full activation of STAT3 and is required for c-fos promoter activation, cell mitogenicity, and transformation. JOURNAL OF BIOLOGICAL CHEMISTRY, 282 (9). pp. 6415-6424. ISSN 0021-9258

Smalley, M. J., Iravani, M., Leao, M., Grigoriadis, A., Kendrick, H., Dexter, T., Fenwick, K., Regan, J. L., Britt, K., McDonald, S., Lord, C. J., MacKay, A., Ashworth, A. (2007) Regulator of G-protein signalling 2 mRNA is differentially expressed in mammary epithelial subpopulations and over-expressed in the majority of breast cancers. BREAST CANCER RESEARCH, 9 (6). ISSN 1465-5411

Esseghir, S., Todd, S. K., Hunt, T., Poulsom, R., Plaza-Menacho, I., Reis-Filho, J. S., Isacke, C. M. (2007) A role for glial cell-derived neurotrophic factor-induced expression by inflammatory cytokines and RET/GFR alpha 1 receptor up-regulation in breast cancer. CANCER RESEARCH, 67 (24). pp. 11732-11741. ISSN 0008-5472

Plaza-Menacho, I., Mologni, L., Sala, E., Gambacorti-Passerini, C., Magee, A. I., Links, T. P., Hofstra, R. M. W., Barford, D., Isacke, C. M. (2007) Sorafenib functions to potently suppress RET tyrosine kinase activity by direct enzymatic inhibition and promoting RET lysosomal degradation independent of proteasomal targeting. JOURNAL OF BIOLOGICAL CHEMISTRY, 282 (40). pp. 29230-29240. ISSN 0021-9258

Rodriguez-Pinilla, S. M., Sarrio, D., Moreno-Bueno, G., Rodriguez-Gil, Y., Martinez, M. A., Hernandez, L., Hardisson, D., Reis-Filho, J. S., Palacios, J. (2007) Sox2: a possible driver of the basal-like phenotype in sporadic breast cancer. MODERN PATHOLOGY, 20 (4). pp. 474-481. ISSN 0893-3952

Gorrini, C., Squatrito, M., Luise, C., Syed, N., Perna, D., Wark, L., Martinato, F., Sardella, D., Verrecchia, A., Bennett, S., Confalonieri, S., Cesaroni, M., Marchesi, F., Gasco, M., Scanziani, E., Capra, M., Mai, S., Nuciforo, P., Crook, T., Lough, J., Amati, B. (2007) Tip60 is a haplo-insufficient tumour suppressor required for an oncogene-induced DNA damage response. NATURE, 448 (7157). pp. 1063-1067. ISSN 0028-0836

Mansson, S. S., Reis-Filho, J., Landberg, G. (2007) Transcriptional upregulation and unmethylation of the promoter region of p16 in invasive basal cell carcinoma cells and partial co-localization with the gamma 2 chain of laminin-332. JOURNAL OF PATHOLOGY, 212 (1). pp. 102-111. ISSN 0022-3417

Balkwill, F. R., Ashworth, A., Bast, R. C., Berek, J. S., Boyd, J., Disis, M. L., Gabra, H., Gore, M. E., Hamilton, T. C., Jacobs, I. J., Kaye, S. B., Kohn, E. C., Mills, G. B., Urban, N. D. (2006) 10th Biennial Helene Harris Memorial Trust Meeting. CANCER RESEARCH, 66 (6). pp. 2904-2906. ISSN 0008-5472

Natrajan, R., Little, S. E., Reis-Filho, J. S., Hing, L., Messahel, B., Grundy, P. E., Dome, J. S., Schneider, T., Vujanic, G. M., Pritchard-Jones, K., Jones, C. (2006) Amplification and overexpression of CACNA1E correlates with relapse in favorable histology Wilms' tumors. CLINICAL CANCER RESEARCH, 12 (24). pp. 7284-7293. ISSN 1078-0432

Horsley, S. W., Mackay, A., Iravani, M., Fenwick, K., Valgeirsson, H., Dexter, T., Ashworth, A., Kearney, L. (2006) Array CGH of fusion gene-positive leukemia-derived cell lines reveals cryptic regions of genomic gain and loss. GENES CHROMOSOMES & CANCER, 45 (6). pp. 554-564. ISSN 1045-2257

Natrajan, R., Williams, R. D., Hing, S. N., Mackay, A., Reis-Filho, J. S., Fenwick, K., Iravani, M., Valgeirsson, H., Grigoriadis, A., Langford, C. F., Dovey, O., Gregory, S. G., Weber, B. L., Ashworth, A., Grundy, P. E., Pritchard-Jones, K., Jones, C. (2006) Array CGH profiling of favourable histology Wilms tumours reveals novel gains and losses associated with relapse. JOURNAL OF PATHOLOGY, 210 (1). pp. 49-58. ISSN 0022-3417

Little, S. E., Vuononvirta, R., Reis-Filho, J. S., Natrajan, R., Iravani, M., Fenwick, K., Mackay, A., Ashworth, A., Pritchard-Jones, K., Jones, C. (2006) Array CGH using whole genome amplification of fresh-frozen and formalin-fixed, paraffin-embedded tumor DNA. GENOMICS, 87 (2). pp. 298-306. ISSN 0888-7543

Chieffi, P., Cozzolino, L., Kisslinger, A., Libertini, S., Staibano, S., Mansueto, G., De Rosa, G., Villacci, A., Vitale, M., Linardopoulos, S., Portella, G., Tramontano, D. (2006) Aurora B expression directly correlates with prostate cancer malignancy and influence prostate cell proliferation. PROSTATE, 66 (3). pp. 326-333. ISSN 0270-4137

Banerjee, S., Reis-Filho, J. S., Ashley, S., Steele, D., Ashworth, A., Lakhani, S. R., Smith, I. E. (2006) Basal-like breast carcinomas: clinical outcome and response to chemotherapy. JOURNAL OF CLINICAL PATHOLOGY, 59 (7). pp. 729-735. ISSN 0021-9746

Natrajan, R., Reis-Filho, J. S., Little, S. E., Messahel, B., Brundler, M. A., Dome, J. S., Grundy, P. E., Vujanic, G. M., Pritchard-Jones, K., Jones, C. (2006) Blastemal expression of type I insulin-like growth factor receptor in Wilms' tumors is driven by increased copy number and correlates with relapse. CANCER RESEARCH, 66 (23). pp. 11148-11155. ISSN 0008-5472

Sleeman, K. E., Kendrick, H., Ashworth, A., Isacke, C. M., Smalley, M. J. (2006) CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells. BREAST CANCER RESEARCH, 8 (1). ISSN 1465-5411

Reis-Filho, J. S., Savage, K., Lambros, M. B. K., James, M., Steele, D., Jones, R. L., Dowsett, M. (2006) Cyclin D1 protein overexpression and CCND1 amplification in breast carcinomas: an immunohistochemical and chromogenic in situ hybridisation analysis. MODERN PATHOLOGY, 19 (7). pp. 999-1009. ISSN 0893-3952

McCabe, N., Turner, N. C., Lord, C. J., Kluzek, K., Bialkowska, A., Swift, S., Giavara, S., O'Connor, M. J., Tutt, A. N., Zdzienicka, M. Z., Smith, G. C. M., Ashworth, A. (2006) Deficiency in the repair of DNA damage by homologous recombination and sensitivity to poly(ADP-ribose) polymerase inhibition. CANCER RESEARCH, 66 (16). pp. 8109-8115. ISSN 0008-5472

Sakamoto, K., Zarrinpashneh, E., Budas, G. R., Pouleur, A. C., Dutta, A., Prescott, A. R., Vanoverschelde, J. L., Ashworth, A., Jovanovic, A., Alessi, D. R., Bertrand, L. (2006) Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPK alpha 2 but not AMPK alpha 1. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 290 (5). E780-E788. ISSN 0193-1849

Tzircotis, G., Thorne, R. F., Isacke, C. M. (2006) Directional sensing of a phorbol ester gradient requires CD44 and is regulated by CD44 phosphorylation. ONCOGENE, 25 (56). pp. 7401-7410. ISSN 0950-9232

Reis-Filho, J. S., Steele, D., Di Palma, S., Jones, R. L., Savage, K., James, M., Milanezi, F., Schmitt, F. C., Ashworth, A. (2006) Distribution and significance of nerve growth factor receptor (NGFR/p75(NTR)) in normal, benign and malignant breast tissue. MODERN PATHOLOGY, 19 (2). pp. 307-319. ISSN 0893-3952

Crighton, D., Wilkinson, S., O'Prey, J., Syed, N., Smith, P., Harrison, P. R., Gasco, M., Garrone, O., Crook, T., Ryan, K. M. (2006) DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. CELL, 126 (1). pp. 121-134. ISSN 0092-8674

Leulier, F., Lhocine, N., Lemaitre, B., Meier, P. (2006) The Drosophila inhibitor of apoptosis protein DIAP2 functions in innate immunity and is essential to resist gram-negative bacterial infection. MOLECULAR AND CELLULAR BIOLOGY, 26 (21). pp. 7821-7831. ISSN 0270-7306

Cleator, S. J., Powles, T. J., Dexter, T., Fulford, L., Mackay, A., Smith, I. E., Valgeirsson, H., Ashworth, A., Dowsett, M. (2006) The effect of the stromal component of breast tumours on prediction of clinical outcome using gene expression microarray analysis. BREAST CANCER RESEARCH, 8 (3). ISSN 1465-5411

Reis-Filho, J. S., Pinheiro, C., Lambros, M. B. K., Milanezi, F., Carvalho, S., Savage, K., Simpson, P. T., Jones, C., Swift, S., Mackay, A., Reis, R. M., Hornick, J. L., Pereira, E. M., Baltazar, F., Fletcher, C. D. M., Ashworth, A., Lakhani, S. R., Schmitt, F. C. (2006) EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. JOURNAL OF PATHOLOGY, 209 (4). pp. 445-453. ISSN 0022-3417

Sturge, J., Wienke, D., Isacke, C. M. (2006) Endosomes generate localized Rho-ROCK-MLC2 based contractile signals via Endo180 to promote adhesion disassembly. JOURNAL OF CELL BIOLOGY, 175 (2). pp. 337-347. ISSN 0021-9525

Smith, P., Syed, N., Crook, T. (2006) Epigenetic inactivation implies a tumor suppressor function in hematologic malignancies for Polo-like kinase 2 but not Polo-like kinase 3. CELL CYCLE (GEORGETOWN, TEX.), 5 (12). pp. 1262-1264. ISSN 1538-4101

Grigoriadis, A., Mackay, A., Reis-Filho, J. S., Steele, D., Iseli, C., Stevenson, B. J., Jongeneel, C. V., Valgeirsson, H., Fenwick, K., Iravani, M., Leao, M., Simpson, A. J. G., Strausberg, R. L., Jat, P. S., Ashworth, A., Neville, A. M., O'Hare, M. J. (2006) Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data. BREAST CANCER RESEARCH, 8 (5). ISSN 1465-5411

Warren, R. M. L., Thompson, D., Pointon, L. J., Hoff, R., Gilbert, F. J., Padhani, A. R., Easton, D. F., Lakhani, S. R., Leach, M. O. (2006) Evaluation of a prospective scoring system designed for a multicenter breast MR imaging screening study. RADIOLOGY, 239 (3). pp. 677-685. ISSN 0033-8419

Honardoust, H. A., Jiang, G., Koivisto, L., Wienke, D., Isacke, C. M., Larjava, H., Hakkinen, L. (2006) Expression of Endo180 is spatially and temporally regulated during wound healing. HISTOPATHOLOGY, 49 (6). pp. 634-648. ISSN 0309-0167

Reis-Filho, J. S., Simpson, P. T., Turner, N. C., Lambros, M. B., Jones, C., Mackay, A., Grigoriadis, A., Sarrio, D., Savage, K., Dexter, T., Iravani, M., Fenwick, K., Weber, B., Hardisson, D., Schmitt, F. C., Palacios, J., Lakhani, S. R., Ashworth, A. (2006) FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas. CLINICAL CANCER RESEARCH, 12 (22). pp. 6652-6662. ISSN 1078-0432

Cleator, S., Tsimelzon, A., Ashworth, A., Dowsett, M., Dexter, T., Powles, T., Hilsenbeck, S., Wong, H., Osborne, C. K., O'Connell, P., Chang, J. C. (2006) Gene expression patterns for doxorubicin (Adriamycin) and cyclophosphamide (Cytoxan) (AC) response and resistance. BREAST CANCER RESEARCH AND TREATMENT, 95 (3). pp. 229-233. ISSN 0167-6806

Bergamaschi, D., Samuels, Y., Sullivan, A., Zvelebil, M., Breyssens, H., Bisso, A., Del Sal, G., Syed, N., Smith, P., Gasco, M., Crook, T., Lu, X. (2006) iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72 polymorphic p53. NATURE GENETICS, 38 (10). pp. 1133-1141. ISSN 1061-4036

Esseghir, S., Reis-Filho, J. S., Kennedy, A., James, M., O'Hare, M. J., Jeffery, R., Poulsom, R., Isacke, C. M. (2006) Identification of transmembrane proteins as potential prognostic markers and therapeutic targets in breast cancer by a screen for signal sequence encoding transcripts. JOURNAL OF PATHOLOGY, 210 (4). pp. 420-430. ISSN 0022-3417

Szlosarek, P. W., Klabatsa, A., Pallaska, A., Sheaff, M., Smith, P., Crook, T., Grimshaw, M. J., Steele, J. P., Rudd, R. M., Balkwill, F. R., Fennell, D. A. (2006) In vivo loss of expression of argininosuccinate synthetase in malignant pleural mesothelioma is a biomarker for susceptibility to arginine depletion. CLINICAL CANCER RESEARCH, 12 (23). pp. 7126-7131. ISSN 1078-0432

Fletcher, O., Johnson, N., Palles, C., dos Santos, I., McCormack, V., Whittaker, J., Ashworth, A., Peto, J. (2006) Inconsistent association between the STK15 f31I genetic polymorphism and breast cancer risk. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 98 (14). pp. 1014-1018. ISSN 0027-8874

Silva, I. D., Johnson, N., Torres-Mejia, G., Fletcher, O., Allen, D. S., Allen, N. E., Key, T. J., Fentiman, I. S., Holly, J. M. P., Peto, J. (2006) The insulin-like growth factor system and mammographic features in premenopausal and postmenopausal women. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 15 (3). pp. 449-455. ISSN 1055-9965

Friedmann, B. J., Caplin, M., Savic, B., Shah, T., Lord, C. J., Ashworth, A., Hartley, J. A., Hochhauser, D. (2006) Interaction of the epidermal growth factor receptor and the DNA-dependent protein kinase pathway following gefitinib treatment. MOLECULAR CANCER THERAPEUTICS, 5 (2). pp. 209-218. ISSN 1535-7163

Clarke, C. L., Sandle, J., Jones, A. A., Sofronis, A., Patani, N. R., Lakhani, S. R. (2006) Mapping loss of heterozygosity in normal human breast cells from BRCA1/2 carriers. BRITISH JOURNAL OF CANCER, 95 (4). pp. 515-519. ISSN 0007-0920

Reis-Filho, J. S., Milanezi, F., Steele, D., Savage, K., Simpson, P. T., Nesland, J. M., Pereira, E. M., Lakhani, S. R., Schmitt, F. C. (2006) Metaplastic breast carcinomas are basal-like tumours. HISTOPATHOLOGY, 49 (1). pp. 10-21. ISSN 0309-0167

Briassouli, P., Chan, F., Linardopoulos, S. (2006) The N-terminal domain of the Aurora-A Phe-31 variant encodes an E3 ubiquitin ligase and mediates ubiquitination of I kappa B alpha. HUMAN MOLECULAR GENETICS, 15 (22). pp. 3343-3350. ISSN 0964-6906

Arias-Lopez, C., Lazaro-Trueba, I., Kerr, P., Lord, C. J., Dexter, T., Iravani, M., Ashworth, A., Silva, A. (2006) P53 modulates homologous recombination by transcriptional regulation of the RAD51 gene. EMBO REPORTS, 7 (2). pp. 219-224. ISSN 1469-221X

Tutt, A., Yarnold, J. (2006) Radiobiology of breast cancer. CLINICAL ONCOLOGY, 18 (3). pp. 166-178. ISSN 0936-6555

Folkerd, E. J., Martin, L. A., Kendall, A., Dowsett, M. (2006) The relationship between factors affecting endogenous oestradiol levels in postmenopausal women and breast cancer. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 102 (1-5). pp. 250-255. ISSN 0960-0760

Costa, F. F., Paixao, V. A., Cavalher, F. P., Ribeiro, K. B., Cunha, I. W., Rinck, J. A., O'Hare, M., Mackay, A., Soares, F. A., Brentani, R. R., Camargo, A. A. (2006) SATR-1 hypomethylation is a common and early event in breast cancer. CANCER GENETICS AND CYTOGENETICS, 165 (2). pp. 135-143. ISSN 0165-4608

Webb, E. L., Rudd, M. F., Sellick, G. S., El Galta, R., Bethke, L., Wood, W., Fletcher, O., Penegar, S., Withey, L., Qureshi, M., Johnson, N., Tomlinson, I., Gray, R., Peto, J., Houlston, R. S. (2006) Search for low penetrance alleles for colorectal cancer through a scan of 1467 non-synonymous SNPs in 2575 cases and 2707 controls with validation by kin-cohort analysis of 14 704 first-degree relatives. HUMAN MOLECULAR GENETICS, 15 (21). pp. 3263-3271. ISSN 0964-6906

Fulford, L. G., Easton, D. F., Reis-Filho, J. S., Sofronis, A., Gillett, C. E., Lakhani, S. R., Hanby, A. (2006) Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast. HISTOPATHOLOGY, 49 (1). pp. 22-34. ISSN 0309-0167

Boskovic, J., Arnold, J. N., Stilion, R., Gordon, S., Sim, R. B., Rivera-Calzada, A., Wienke, D., Isacke, C. M., Martinez-Pomares, L., Llorca, O. (2006) Structural model for the mannose receptor family uncovered by electron microscopy of Endo180 and the mannose receptor. JOURNAL OF BIOLOGICAL CHEMISTRY, 281 (13). pp. 8780-8787. ISSN 0021-9258

Leulier, F., Ribeiro, P. S., Palmer, E., Tenev, T., Takahashi, K., Robertson, D., Zachariou, A., Pichaud, F., Ueda, R., Meier, P. (2006) Systematic in vivo RNAi analysis of putative components of the Drosophila cell death machinery. CELL DEATH AND DIFFERENTIATION, 13 (10). pp. 1663-1674. ISSN 1350-9047

Lord, C. J., Garrett, M. D., Ashworth, A. (2006) Targeting the double-strand DNA break repair pathway as a therapeutic strategy. CLINICAL CANCER RESEARCH, 12 (15). pp. 4463-4468. ISSN 1078-0432

Syed, N., Smith, P., Sullivan, A., Spender, L. C., Dyer, M., Karran, L., O'Nions, J., Allday, M., Hoffmann, I., Crawford, D., Griffin, B., Farrell, P. J., Crook, T. (2006) Transcriptional silencing of Polo-like kinase 2 (SNK/PLK2) is a frequent event in B-cell malignancies. BLOOD, 107 (1). pp. 250-256. ISSN 0006-4971

Lambros, M. B. K., Simpson, P. T., Jones, C., Natrajan, R., Westbury, C., Steele, D., Savage, K., Mackay, A., Schmitt, F. C., Ashworth, A., Reis-Filho, J. S. (2006) Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridization. LABORATORY INVESTIGATION, 86 (4). pp. 398-408. ISSN 0023-6837

Croft, D. R., Coleman, M. L., Li, S. X., Robertson, D., Sullivan, T., Stewart, C. L., Olson, M. F. (2005) Actin-myosin-based contraction is responsible for apoptotic nuclear disintegration. JOURNAL OF CELL BIOLOGY, 168 (2). pp. 245-255. ISSN 0021-9525

Sorrentino, R., Libertini, S., Pallante, P. L., Troncone, G., Palombini, L., Bavetsias, V., Spalletti-Cernia, D., Laccetti, P., Linardopoulos, S., Chieffi, P., Fusco, A., Portella, G. (2005) Aurora B overexpression associates with the thyroid carcinoma undifferentiated phenotype and is required for thyroid carcinoma cell proliferation. JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM, 90 (2). pp. 928-935. ISSN 0021-972X

Kendall, A., Dowsett, M. (2005) Biological aspects of tamoxifen resistance versus aromatase inhibitors. MIMS ADVANCES IN BREAST CANCER, 2 . pp. 4-7.

McCabe, N., Lord, C. J., Tutt, A. N. J., Martin, N. M. B., Smith, G. C. M., Ashworth, A. (2005) BRCA2-deficient CAPAN-1 cells are extremely sensitive to the inhibition of poly (ADP-Ribose) polymerase. CANCER BIOLOGY & THERAPY, 4 (9). pp. 934-936. ISSN 1538-4047

Zola, H., Swart, B., Nicholson, I., Aasted, B., Bensussan, A., Boumsell, L., Buckley, C., Clark, G., Drbal, K., Engel, P., Hart, D., Horejsi, V., Isacke, C., Macardle, P., Malavasi, F., Mason, D., Olive, D., Saalmueller, A., Schlossman, S. F., Schwartz-Albiez, R., Simmons, P., Tedder, T. F., Uguccioni, M., Warren, H. (2005) CD molecules 2005: human cell differentiation molecules. BLOOD, 106 (9). pp. 3123-3126. ISSN 0006-4971

Tzircotis, G., Thorne, R. F., Isacke, C. M. (2005) Chemotaxis towards hyaluronan is dependent on CD44 expression and modulated by cell type variation in CD44-hyaluronan binding. JOURNAL OF CELL SCIENCE, 118 (21). pp. 5119-5128. ISSN 0021-9533

Simpson PT, Gale T, Reis-Filho JS, Jones C, Parry S, Sloane JP, Hanby A, Pinder SE, Lee AHS, Humphreys S, Ellis IO, Lakhani SR (2005) Columnar cell lesions of the breast: The missing link in breast cancer progression? A morphological and molecular analysis. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 29 (6). pp. 734-746. ISSN 0147-5185

Gui GPH, Joubert DJ, Reichert R, Ward A, Lakhani S, Osin P, Nerurkar A, A'Hern R, Benson K, Underwood SR (2005) Continued axillary sampling is unnecessary and provides no further information to sentinel node biopsy in staging breast cancer. EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 31 (7). pp. 707-714. ISSN 0748-7983

Sakamoto, K., McCarthy, A., Smith, D., Green, K. A., Hardie, D. G., Ashworth, A., Alessi, D. R. (2005) Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction. EMBO JOURNAL, 24 (10). pp. 1810-1820. ISSN 0261-4189

Reis, R. M., Reis-Filho, J. S., Longatto, A., Tomarev, S., Silva, P., Lopes, J. M. (2005) Differential Prox-1 and CD 31 expression in mucousae, cutaneous and soft tissue vascular lesions and tumors. PATHOLOGY, RESEARCH AND PRACTICE, 201 (12). pp. 771-776. ISSN 0344-0338

Smalley, M. J., Signoret, N., Robertson, D., Tilley, A., Hann, A., Ewan, K., Ding, Y. N., Paterson, H., Dale, T. C. (2005) Dishevelled (Dvl-2) activates canonical Wnt signalling in the absence of cytoplasmic puncta. JOURNAL OF CELL SCIENCE, 118 (22). pp. 5279-5289. ISSN 0021-9533

Martin, L. A., Farmer, I., Johnston, S. R. D., Ali, S., Dowsett, M. (2005) Elevated ERK1/ERK2/estrogen receptor cross-talk enhances estrogen-mediated signaling during long-term estrogen deprivation. ENDOCRINE-RELATED CANCER, 12 (Supplement 1). S75-S84. ISSN 1351-0088

Thomas, E. K., Nakamura, M., Wienke, D., Isacke, C. M., Pozzio, A., Liang, P. (2005) Endo180 binds to the C-terminal region of type I collagen. JOURNAL OF BIOLOGICAL CHEMISTRY, 280 (24). pp. 22596-22605. ISSN 0021-9258

MacFadyen, J. R., Haworth, O., Roberston, D., Hardie, D., Webster, M. T., Morris, H. R., Panico, M., Sutton-Smith, M., Dell, A., van der Geer, P. R., Wienke, D., Buckley, C. D., Isacke, C. M. (2005) Endosialin (TEM1, CD248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium. FEBS LETTERS, 579 (12). pp. 2569-2575. ISSN 0014-5793

Dua RS, Gui GPH, Isacke CM (2005) Endothelial adhesion molecules in breast cancer invasion into the vascular and lymphatic systems. EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 31 (8). pp. 824-832. ISSN 0748-7983

Reis-Filho, J. S., Schmitt, F. C. D. (2005) Fluorescence in situ hybridization, comparative genomic hybridization, and other molecular biology techniques in the analysis of effusions. DIAGNOSTIC CYTOPATHOLOGY, 33 (5). pp. 294-299. ISSN 8755-1039

Brookman-Amissah, N., Duchesnes, C., Williamson, M. P., Wang, Q., Ahmed, A., Feneley, M. R., Mackay, A., Freeman, A., Fenwick, K., Iravani, M., Weber, B., Ashworth, A., Masters, J. R. (2005) Genome-wide screening for genetic changes in a matched pair of benign and prostate cancer cell lines using array CGH. PROSTATE CANCER AND PROSTATIC DISEASES, 8 (4). pp. 335-343. ISSN 1365-7852

Cleator, S. J., Makris, A., Ashley, S. E., Lal, R., Powles, T. J. (2005) Good clinical response of breast cancers to neoa uvant chemoendocrine therapy is associated with improved overall survival. ANNALS OF ONCOLOGY, 16 (2). pp. 267-272. ISSN 0923-7534

Tenev, T., Zachariou, A., Wilson, R., Ditzel, M., Meier, P. (2005) IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms. NATURE CELL BIOLOGY, 7 (1). pp. 70-77. ISSN 1465-7392

Howard, B., Panchal, H., McCarthy, A., Ashworth, A. (2005) Identification of the scaramanga gene implicates Neuregulin3 in mammary gland specification. GENES & DEVELOPMENT, 19 (17). pp. 2078-2090. ISSN 0890-9369

Smalley, M. J., Titley, I., Ashworth, A. (2005) An improved definition of mouse mammary epithelial side population cells. CYTOTHERAPY, 7 (6). pp. 497-508. ISSN 1465-3249

Johnson, N., Fletcher, O., Naceur-Lombardelli, C., Silva, I. D., Ashworth, A., Peto, J. (2005) Interaction between CHEK2*1100delC and other low-penetrance breast-cancer susceptibility genes: a familial study. LANCET, 366 (9496). pp. 1554-1557. ISSN 0140-6736

Johnston SR, Martin LA, Dowsett M (2005) Life following aromatase inhibitors - where now for endocrine sequencing?. BREAST CANCER RESEARCH AND TREATMENT, 93 (Supplement 1). S19-S25. ISSN 0167-6806

Smalley, M. J., Clarke, R. B. (2005) The mammary gland "Side Population": A putative stem/progenitor cell marker? JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, 10 (1). pp. 37-47. ISSN 1083-3021

Dowsett, M., Martin, L. A., Smith, I., Johnston, S. (2005) Mechanisms of resistance to aromatase inhibitors. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 95 (1-5). pp. 167-172. ISSN 0960-0760

Reis-Filho, J. S., Milanezi, F., Carvalho, S., Simpson, P. T., Steele, D., Savage, K., Lambros, M. B. K., Pereira, E. M., Nesland, J. M., Lakhani, S. R., Schmitt, F. C. (2005) Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis. BREAST CANCER RESEARCH, 7 (6). R1028-R1035. ISSN 1465-5411

Reis-Filho JS, Simpson PT, Jones C, Steele D, Mackay A, Iravani M, Fenwick K, Valgeirsson H, Lambros M, Ashworth A, Palacios J, Schmitt F, Lakhani SR (2005) Pleomorphic lobular carcinoma of the breast: role of comprehensive molecular pathology in characterization of an entity. JOURNAL OF PATHOLOGY, 207 (1). pp. 1-13. ISSN 0022-3417

Lakhani, S. R., Reis-Filho, J. S,. Fulford, L., Penault-Llorca, F., van der Vjiver, M., Parry, S., Bishop, T., Benitez, J., Rivas, C., Bignon, Y. J,. Chang-Claude, J., Hamann, U., Cornelisse, C. J., Devilee, P., Beckmann, M. W., Nestle-Kramling, C., Daly, P. A., Haites, N., Varley, J., Lalloo, F., Evans, G., Maugard, C., Meijers-Heijboer, H., Klijn, J. G. M., Olah, E., Gusterson, B. A., Pilotti, S., Radice, P., Scherneck, S., Sobol, H., Jacquemier, J., Wagner, T., Peto, J., Stratton, M. R., McGuffog, L., Easton, D. F. (2005) Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype. CLINICAL CANCER RESEARCH, 11 (14). pp. 5175-5180. ISSN 1078-0432

Warren, R. M. L., Pointon, L., Thompson, D., Hoff, R., Gilbert, F. J., Padhani, A., Easton, D., Lakhani, S. R., Leach, M. O., UK Magnetic Resonance Imaging in Breast Screening (MARIBS) Study Group (includes Rosalind Eeles), [Group Author] (2005) Reading protocol for dynamic contrast-enhanced MR images of the breast: Sensitivity and specificity analysis. RADIOLOGY, 236 (3). pp. 779-788. ISSN 0033-8419

Kenny, P. A., Enver, T., Ashworth, A. (2005) Receptor and secreted targets of Wnt-I/beta-catenin signalling in mouse mammary epithelial cells. BMC CANCER, 5 . ISSN 1471-2407

Buckley, C. D., Halder, S., Hardie, D., Reynolds, G., Torensma, R., De Villeroche, V. J., Brouty-Boye, D., Isacke, C. M. (2005) Report on antibodies submitted to the stromal cell section of HLDA8. CELLULAR IMMUNOLOGY, 236 (1-2). pp. 29-41. ISSN 0008-8749

Stephens, P., Edkins, S., Davies, H., Greenman, C., Cox, C., Hunter, C., Bignell, G., Teague, J., Smith, R., Stevens, C., O'Meara, S., Parker, A., Tarpey, P., Avis, T., Barthorpe, A., Brackenbury, L., Buck, G., Butler, A., Clements, J., Cole, J., Dicks, E., Edwards, K., Forbes, S., Gorton, M., Gray, K., Halliday, K., Harrison, R., Hills, K., Hinton, J., Jones, D., Kosmidou, V., Laman, R., Lugg, R., Menzies, A., Perry, J., Petty, R., Raine, K., Shepherd, R., Small, A., Solomon, H., Stephens, Y., Tofts, C., Varian, J., Webb, A., West, S., Widaa, S., Yates, A., Brasseur, F., Cooper, C. S., Flanagan, A. M., Green, A., Knowles, M., Leung, S. Y., Looijenga, L. H. J., Malkowicz, B., Pierotti, M. A., Teh, B., Yuen, S. T., Nicholson, A. G., Lakhani, S., Easton, D. F., Weber, B. L., Stratton, M. R., Futreal, P. A., Wooster, R. (2005) A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer. NATURE GENETICS, 37 (6). pp. 590-592. ISSN 1061-4036

Krutzfeldt M, Ellis M, Weekes DB, Bull JJ, Eilers M, Vivanco MDM, Sellers WR, Mittnacht S (2005) Selective ablation of retinoblastoma protein function by the RET finger protein. MOLECULAR CELL, 18 (2). pp. 213-224. ISSN 1097-2765

Farmer, H., McCabe, N., Lord, C. J., Tutt, A. N. J., Johnson, D. A., Richardson, T. B., Santarosa, M., Dillon, K. J., Hickson, I., Knights, C., Martin, N. M. B., Jackson, S. P., Smith, G. C. M., Ashworth, A. (2005) Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. NATURE, 434 (7035). pp. 917-921. ISSN 0028-0836

Turner N, Tutt A, Ashworth A (2005) Targeting the DNA repair defect of BRCA tumours. CURRENT OPINION IN PHARMACOLOGY, 5 (4). pp. 388-393. ISSN 1471-4892

Jacquemier J, Padovani L, Rabayrol L, Lakhani SR, Penault-Llorca F, Denoux Y, Fiche M, Figueiro P, Maisongrosse V, Ledoussal V, Penuela JM, Udvarhely N, El Makdissi G, Ginestier C, Geneix J, Charafe-Jauffret E, Xerri L, Eisinger F, Birnbaum D (2005) Typical medullary breast carcinomas have a basal/myoepithelial phenotype. JOURNAL OF PATHOLOGY, 207 (3). pp. 260-268. ISSN 0022-3417

Chieffi, P., Troncone, G., Caleo, A., Libertini, S., Linardopoulos, S., Tramontano, D., Portella, G. (2004) Aurora B expression in normal testis and seminomas. JOURNAL OF ENDOCRINOLOGY, 181 (2). pp. 263-270. ISSN 0022-0795

Sleeman KE, Harries M, Gore ME (2004) Bilateral palmar contractures as a paraneoplastic syndrome in primary peritoneal carcinoma. CLINICAL ONCOLOGY, 16 (1). pp. 77-78. ISSN 0936-6555

Gudmundsdottir K, Ashworth A (2004) BRCA2 in meiosis: turning over a new leaf. TRENDS IN CELL BIOLOGY, 14 (8). pp. 401-404. ISSN 0962-8924

Reis-Filho, J. S., Fulford, L. G., Crebassa, B., Carpentier, S., Lakhani, S. R. (2004) Collagenous spherulosis in an adenomyoepithelioma of the breast. JOURNAL OF CLINICAL PATHOLOGY, 57 (1). pp. 83-86. ISSN 0021-9746

Remak, E., Brazil, L. (2004) Cost of managing women presenting with stage IV breast cancer in the United Kingdom. BRITISH JOURNAL OF CANCER, 91 (1). pp. 77-83. ISSN 0007-0920

Clarke CL, Sandle J, Parry SC, Reis-Filho JS, O'Hare MJ, Lakhani SR (2004) Cytokeratin 5/6 in normal human breast: lack of evidence for a stem cell phenotype. JOURNAL OF PATHOLOGY, 204 (2). pp. 147-152. ISSN 0022-3417

Hussain, S., Wilson, J. B., Medhurst, A. L., Hejna, J., Witt, E., Ananth, S., Davies, A., Masson, J. Y., Moses, R., West, S. C., de Winter, J. P., Ashworth, A., Jones, N. J., Mathew, C. G. (2004) Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways. HUMAN MOLECULAR GENETICS, 13 (12). pp. 1241-1248. ISSN 0964-6906

Simpson PT, Gale T, Reis-Filho JS, Jones C, Parry S, Steele D, Cossu A, Budroni M, Palmieri G, Lakhani SR (2004) Distribution and significance of 14-3-3 sigma, a novel myoepithelial marker, in normal, benign, and malignant breast tissue. JOURNAL OF PATHOLOGY, 202 (3). pp. 274-285. ISSN 0022-3417

Howard MJ, Chambers MG, Mason RM, Isacke CM (2004) Distribution of Endo180 receptor and ligand in developing articular cartilage. OSTEOARTHRITIS AND CARTILAGE, 12 (1). pp. 74-82. ISSN 1063-4584

Ciani, L., Krylova, O., Smalley, M. J., Dale, T. C., Salinas, P. C. (2004) A divergent canonical WNT-signaling pathway regulates microtubule dynamics: Dishevelled signals locally to stabilize microtubules. JOURNAL OF CELL BIOLOGY, 164 (2). pp. 243-253. ISSN 0021-9525

Gudmundsdottir, K., Lord, C. J., Witt, E., Tutt, A. N. J., Ashworth, A. (2004) DSS1 is required for RAD51 focus formation and genomic stability in mammalian cells. EMBO REPORTS, 5 (10). pp. 989-993. ISSN 1469-221X

Angele, S., Jones, C., Reis-Filho, J. S., Fulford, L. G., Treilleux, I., Lakhani, S. R., Hall, J. (2004) Expression of ATM, p53, and the MRE11-Rad50-NBS1 complex in myoepithelial cells from benign and malignant proliferations of the breast. JOURNAL OF CLINICAL PATHOLOGY, 57 (11). pp. 1179-1184. ISSN 0021-9746

Angelova A, Tenev T, Varadinova T (2004) Expression of cellular proteins Bcl-X-L XIAP and Bax involved in apoptosis in cells infected with Herpes simplex virus 1 and effect of pavine alkaloid (-)-thalimonine on virus-induced suppression of apoptosis. ACTA VIROLOGICA, 48 (3). pp. 193-196. ISSN 0001-723X

Jones, C., Mackay, A., Grigoriadis, A., Cossu, A., Reis-Filho, J. S., Fulford, L., Dexter, T., Davies, S., Bulmer, K., Ford, E., Parry, S., Budroni, M., Palmieri, G., Neville, A. M., O'Hare, M. J., Lakhani, S. R. (2004) Expression profiling of purified normal human luminal and myoepithelial breast cells: Identification of novel prognostic markers for breast cancer. CANCER RESEARCH, 64 (9). pp. 3037-3045. ISSN 0008-5472

Millis, R. R., Pinder, S. E., Ryder, K., Howitt, R., Lakhani, S. R. (2004) Grade of recurrent in situ and invasive carcinoma following treatment of pure ductal carcinoma in situ of the breast. BRITISH JOURNAL OF CANCER, 90 (8). pp. 1538-1542. ISSN 0007-0920

Clayton H, Titley I, Vivanco MdM (2004) Growth and differentiation of progenitor/stem cells derived from the human mammary gland. EXPERIMENTAL CELL RESEARCH, 297 (2). pp. 444-460. ISSN 0014-4827

Sun, C. B., Newbatt, Y., Douglas, L., Workman, P., Aherne, W., Linardopoulos, S. (2004) High-throughput screening assay for identification of small molecule inhibitors of Aurora2/STK15 kinase. JOURNAL OF BIOMOLECULAR SCREENING, 9 (5). pp. 391-397. ISSN 1087-0571

Virgintino D, Errede M, Robertson D, Capobianco C, Girolamo F, Vimercati A, Bertossi M, Roncali L (2004) Immunolocalization of tight junction proteins in the adult and developing human brain. HISTOCHEMISTRY AND CELL BIOLOGY, 122 (1). pp. 51-59. ISSN 0948-6143

Gui GPH, Behranwala KA, Abdullah N, Seet J, Osin P, Nerurkar A, Lakhani SR (2004) The inframammary fold: contents, clinical significance and implications for immediate breast reconstruction. BRITISH JOURNAL OF PLASTIC SURGERY, 57 (2). pp. 146-149. ISSN 0007-1226

Cruz, J., Reis-Filho, J. S., Lopes, J. M. (2004) Malignant peripheral nerve sheath tumour-like primary cutaneous malignant melanoma. JOURNAL OF CLINICAL PATHOLOGY, 57 (2). pp. 218-220. ISSN 0021-9746

Jones, C., Ford, E., Gillett, C., Ryder, K., Merrett, S., Reis-Filho, J. S., Fulford, L. G., Hanby, A., Lakhani, S. R. (2004) Molecular cytogenetic identification of subgroups of grade III invasive ductal breast carcinomas with different clinical outcomes. CLINICAL CANCER RESEARCH, 10 (18). pp. 5988-5997. ISSN 1078-0432

Tzircotis, G., Thorne, R. F., Isacke, C. M. (2004) A new spreadsheet method for the analysis of bivariate flow cytometric data. BMC CELL BIOLOGY, 5 . p. 10. ISSN 1471-2121

Giannini AL, Mazor M, Orme M, Vivanco MdM, Waxman J, Kypta RM (2004) Nuclear export of alpha-catenin: overlap between nuclear export signal sequences and the beta-catenin binding site. EXPERIMENTAL CELL RESEARCH, 295 (1). pp. 150-160. ISSN 0014-4827

Reis-Filho JS, Simpson PT, Fulford LG, Martins A, Schmitt FC (2004) p63-driven nuclear accumulation of beta-catenin is not a frequent event in human neoplasms. PATHOLOGY, RESEARCH AND PRACTICE, 199 (12). pp. 785-793. ISSN 0344-0338

Lakhani, S. R., Manek, S., Penault-Llorca, F., Flanagan, A., Arnout, L., Merrett, S., McGuffog, L., Steele, D., Devilee, P., Klijn, J. G. M., Meijers-Heijboer, H., Radice, P., Pilotti, S., Nevanlinna, H., Butzow, R., Sobol, H., Jacquemier, J., Lyonet, D. S., Neuhausen, S. L., Weber, B., Wagner, T., Winqvist, R., Bignon, Y. J., Monti, F., Schmitt, F., Lenoir, G., Seitz, S., Hamman, U., Pharoah, P., Lane, G., Ponder, B., Bishop, D. T., Easton, D. F. (2004) Pathology of ovarian cancers in BRCA1 and BRCA2 carriers. CLINICAL CANCER RESEARCH, 10 (7). pp. 2473-2481. ISSN 1078-0432

Marani, M., Hancock, D., Lopes, R., Tenev, T., Downward, J., Lemoine, N. R. (2004) Role of Bim in the survival pathway induced by Raf in epithelial cells. ONCOGENE, 23 (14). pp. 2431-2441. ISSN 0950-9232

Billon, N., Terrinoni, A., Jolicoeur, C., McCarthy, A., Richardson, W. D., Melino, G., Raff, M. (2004) Roles for p53 and p73 during oligodendrocyte development. DEVELOPMENT, 131 (6). pp. 1211-1220. ISSN 0950-1991

Preto, A., Cameselle-Teijeiro, J., Moldes-Boullosa, J., Soares, P., Cameselle-Teijeiro, J. F., Silva, P., Reis-Filho, J. S., Reyes-Santias, R. M., Alfonsin-Barreiro, N., Forteza, J., Sobrinho-Simoes, M. (2004) Telomerase expression and proliferative activity suggest a stem cell role for thyroid solid cell nests. MODERN PATHOLOGY, 17 (7). pp. 819-826. ISSN 0893-3952

Baum, M., Buzdar, A., Cuzick, J., Forbes, J., Houghton, J., Howell, A., Sahmoud, T., [The ATAC (Arimidex, Tamoxifen Alone or in Combination) Trialists' Group (includes M Dowsett)] (2003) Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early-stage breast cancer. Results of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial efficacy and safety update analyses. CANCER, 98 (9). pp. 1802-1810. ISSN 0008-543X

Logarajah, S., Hunter, P., Kraman, M., Steele, D., Lakhani, S., Bobrow, L., Venkitaraman, A., Wagner, S. (2003) BCL-6 is expressed in breast cancer and prevents mammary epithelial differentiation. ONCOGENE, 22 (36). pp. 5572-5578. ISSN 0950-9232

Warren, R., Lakhani, S. R. (2003) Can the stroma provide the clue to the cellular basis for mammographic density? BREAST CANCER RESEARCH, 5 (5). pp. 225-227. ISSN 1465-5411

Mackay, A., Jones, C., Dexter, T., Silva, R. L. A., Bulmer, K., Jones, A., Simpson, P., Harris, R. A., Jat, P. S., Neville, A. M., Reis, L. F. L., Lakhani S. R., O'Hare, M. J. (2003) cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells. ONCOGENE, 22 (17). pp. 2680-2688. ISSN 0950-9232

Tutt, A., Connor, F., Bertwistle, D., Kerr, P., Peacock, J., Ross, G., Ashworth, A. (2003) Cell cycle and genetic background dependence of the effect of loss of BRCA2 on ionizing radiation sensitivity. ONCOGENE, 22 (19). pp. 2926-2931. ISSN 0950-9232

Jones C, Merrett S, Thomas VA, Barker TH, Lakhani SR (2003) Comparative genomic hybridization analysis of bilateral hyperplasia of usual type of the breast. JOURNAL OF PATHOLOGY, 199 (2). pp. 152-156. ISSN 0022-3417

Trompouki, E., Hatzivassiliou, E., Tsichritzis, T., Farmer, H., Ashworth, A., Mosialos, G. (2003) CYLD is a deubiquitinating enzyme that negatively regulates NF-kappa B activation by TNFR family members. NATURE, 424 (6950). pp. 793-796. ISSN 0028-0836

Ditzel M, Wilson R, Tenev T, Zachariou A, Paul A, Deas E, Meier P (2003) Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis. NATURE CELL BIOLOGY, 5 (5). pp. 467-473. ISSN 1465-7392

Hussain, S., Witt, E., Huber, P. A. J., Medhurst, A. L., Ashworth, A., Mathew, C. G. (2003) Direct interaction of the Fanconi anaemia protein FANCG with BRCA2/FANCD1. HUMAN MOLECULAR GENETICS, 12 (19). pp. 2503-2510. ISSN 0964-6906

Reis-Filho JS, Simpson PT, Martins A, Preto A, Gartner F, Schmitt FC (2003) Distribution of p63, cytokeratins 5/6 and cytokeratin 14 in 51 normal and 400 neoplastic human tissue samples using TARP-4 multi-tumor tissue microarray. VIRCHOWS ARCHIV, 443 (2). pp. 122-132. ISSN 0945-6317

Simpson PT, Shoker BS, Barraclough R, Halliwell N, Rudland PS, Sibson DR, Davies MPA (2003) Examination of tumour histopathology and gene expression in a neu/S100A4 transgenic model of metastatic breast cancer. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 84 (4). pp. 173-184. ISSN 0959-9673

Alvi, A. J., Clayton, H., Joshi, C., Enver, T., Ashworth, A., Vivanco, M., Dale, T. C., Smalley, M. J. (2003) Functional and molecular characterisation of mammary side population cells. BREAST CANCER RESEARCH, 5 (1). R1-R8. ISSN 1465-5411

Gascoyne, D. M., Kypta, R. M., Vivanco, M. D. M. (2003) Glucocorticoids inhibit apoptosis during fibrosarcoma development by transcriptionally activating Bcl-x(L). JOURNAL OF BIOLOGICAL CHEMISTRY, 278 (20). pp. 18022-18029. ISSN 0021-9258

Orme MH, Giannini AL, Vivanco MD, Kypta RM (2003) Glycogen synthase kinase-3 and Axin function in a beta-catenin-independent pathway that regulates neurite outgrowth in neuroblastorna cells. MOLECULAR AND CELLULAR NEUROSCIENCE, 24 (3). pp. 673-686. ISSN 1044-7431

Sturge, J., Wienke, D., East, L., Jones, G. E., Isacke, C. M. (2003) GPI-anchored uPAR requires Endo180 for rapid directional sensing during chemotaxis. JOURNAL OF CELL BIOLOGY, 162 (5). pp. 789-794. ISSN 0021-9525

Zachariou, A., Tenev, T., Goyal, L., Agapite, J., Steller, H., Meier, P. (2003) IAP-antagonists exhibit non-redundant modes of action through differential DIAP1 binding. EMBO JOURNAL, 22 (24). pp. 6642-6652. ISSN 0261-4189

Wienke, D., MacFadyen, J. R., Isacke, C. M. (2003) Identification and characterization of the endocytic transmembrane glycoprotein Endo180 as a novel collagen receptor. MOLECULAR BIOLOGY OF THE CELL, 14 (9). pp. 3592-3604. ISSN 1059-1524

Ewart-Toland A, Briassouli P, de Koning JP, Mao JH, Yuan JW, Chan F, MacCarthy-Morrogh L, Ponder BAJ, Nagase H, Burn J, Ball S, Almeida M, Linardopoulos S, Balmain A (2003) Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human. NATURE GENETICS, 34 (4). pp. 403-412. ISSN 1061-4036

Gascoyne, D. M., Hixon, M. L., Gualberto, A., Vivanco, M. (2003) Loss of mitotic spindle checkpoint activity predisposes to chromosomal instability at early stages of fibrosarcoma development. CELL CYCLE (GEORGETOWN, TEX.), 2 (3). pp. 238-245. ISSN 1538-4101

Roca, R., Kypta, R. M., Vivanco, M. D. (2003) Loss of P16(INK4a) results in increased glucocorticoid receptor activity during fibrosarcoma development. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 100 (6). pp. 3113-3118. ISSN 0027-8424

Sullivan A, Uff CR, Isacke CM, Thorne RF (2003) PACE-1, a novel protein that interacts with the C-terminal domain of ezrin. EXPERIMENTAL CELL RESEARCH, 284 (2). pp. 224-238. ISSN 0014-4827

Reis-Filho JS, Fulford LG, Freeman A, Lakhani SR (2003) Pathologic quiz case - A 93-year-old woman with an enlarged and tender left breast. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 127 (12). pp. 1626-1628. ISSN 0003-9985

Warren, M., Lord, C. J., Masabanda, J., Griffin, D., Ashworth, A. (2003) Phenotypic effects of heterozygosity for a BRCA2 mutation. HUMAN MOLECULAR GENETICS, 12 (20). pp. 2645-2656. ISSN 0964-6906

Puebla, I., Esseghir, S., Mortlock, A., Brown, A., Crisanti, A., Low, W. (2003) A recombinant H1 histone-based system for efficient delivery of nucleic acids. JOURNAL OF BIOTECHNOLOGY, 105 (3). pp. 215-226. ISSN 0168-1656

Spicer, J., Rayter, S., Young, N., Elliott, R., Ashworth, A., Smith, D. (2003) Regulation of the Wnt signalling component PAR1A by the Peutz-Jeghers syndrome kinase LKB1. ONCOGENE, 22 (30). pp. 4752-4756. ISSN 0950-9232

Foray, N., Marot, D., Gabriel, A., Randrianarison, V., Carr, A. M., Perricaudet, M., Ashworth, A., Jeggo, P. (2003) A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein. EMBO JOURNAL, 22 (11). pp. 2860-2871. ISSN 0261-4189

East, L., McCarthy, A., Wienke, D., Sturge, J., Ashworth, A., Isacke, C. M. (2003) A targeted deletion in the endocytic receptor gene Endo180 results in a defect in collagen uptake. EMBO REPORTS, 4 (7). pp. 710-716. ISSN 1469-221X

Rivera-Calzada, A., Robertson, D., MacFadyen, J. R., Boskovic, J., Isacke, C. M., Llorca, O. (2003) Three-dimensional interplay among the ligand-binding domains of the urokinase-plasminogen-activator-receptor-associated protein, Endo180. EMBO REPORTS, 4 (8). pp. 807-812. ISSN 1469-221X

Virgintino D, Errede M, Robertson D, Girolamo F, Masciandaro A, Bertossi M (2003) VEGF expression is developmentally regulated during human brain angiogenesis. HISTOCHEMISTRY AND CELL BIOLOGY, 119 (3). pp. 227-232. ISSN 0948-6143

Tiffin N, Williams RD, Robertson D, Hill S, Shipley J, Pritchard-Jones K (2003) WT1 expression does not disrupt myogenic differentiation in C2C12 murine myoblasts or in human rhabdomyosarcoma. EXPERIMENTAL CELL RESEARCH, 287 (1). pp. 155-165. ISSN 0014-4827

Novelli, M., Cossu, A., Oukrif, D., Quaglia, A., Lakhani, S., Poulsom, R., Sasieni, P., Carta, P., Contini, M., Pasca, A., Palmieri, G., Bodmer, W., Tanda, F., Wright, N. (2003) X-inactivation patch size in human female tissue confounds the assessment of tumor clonality. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 100 (6). pp. 3311-3314. ISSN 0027-8424

Vidarsson H, Mikaelsdottir EK, Rafnar T, Bertwistle D, Ashworth A, Eyfjord JE, Valgeirsdottir S (2002) BRCA1 and BRCA2 bind Stat5a and suppress its transcriptional activity. FEBS LETTERS, 532 (1-2). pp. 247-252. ISSN 0014-5793

Howard, M. J., Isacke, C. M. (2002) The C-type lectin receptor Endo180 displays internalization and recycling properties distinct from other members of the mannose receptor family. JOURNAL OF BIOLOGICAL CHEMISTRY, 277 (35). pp. 32320-32331. ISSN 0021-9258

East, L., Rushton, S., Taylor, M. E., Isacke, C. M. (2002) Characterization of sugar binding by the mannose receptor family member, Endo180. JOURNAL OF BIOLOGICAL CHEMISTRY, 272 (52). pp. 50469-50475. ISSN 0021-9258

Wilson R, Goyal L, Ditzel M, Zachariou A, Baker DA, Agapite J, Steller H, Meier P (2002) The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis. NATURE CELL BIOLOGY, 4 (6). pp. 445-450. ISSN 1465-7392

Theodosiou, A., Ashworth, A. (2002) Differential effects of stress stimuli on a JNK-inactivating phosphatase. ONCOGENE, 21 (15). pp. 2387-2397. ISSN 0950-9232

Tutt, A. N. J., van Oostrom, C. T. M., Ross, G. M., van Steeg, H., Ashworth, A. (2002) Disruption of Brca2 increases the spontaneous mutation rate in vivo: synergism with ionizing radiation. EMBO REPORTS, 3 (3). pp. 255-260. ISSN 1469-221X

Virgintino D, Robertson D, Errede M, Benagiano V, Tauer U, Roncali L, Bertossi M (2002) Expression of caveolin-1 in human brain microvessels. NEUROSCIENCE, 115 (1). pp. 145-152. ISSN 0306-4522

Virgintino D, Robertson D, Errede M, Benagiano V, Girolamo F, Maiorano E, Roncali L, Bertossi M (2002) Expression of P-glycoprotein in human cerebral cortex microvessels. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 50 (12). pp. 1671-1676. ISSN 0022-1554

Suzuki RN, Entwistle A, Atherton AJ, Clarke C, Lakhani SR, O'Hare MJ (2002) The expression patterns of integrin subunits on human breast tissues obtained during pregnancy. CELL BIOLOGY INTERNATIONAL, 26 (7). pp. 593-598. ISSN 1065-6995

Isacke CM, Yarwood H (2002) The hyaluronan receptor, CD44. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 34 (7). pp. 718-721. ISSN 1357-2725

Ditzel M, Meier P (2002) IAP degradation: decisive blow or altruistic sacrifice?. TRENDS IN CELL BIOLOGY, 12 (10). pp. 449-452. ISSN 0962-8924

Fraser, E., Young, N., Dajani, R., Franca-Koh, J., Ryves, J., Williams, R. S., Yeo, M., Webster, M. T., Richardson, C., Smalley, M. J., Pearl, L. H., Harwood, A., Dale, T. C. (2002) Identification of the Axin and Frat binding region of glycogen synthase kinase-3. JOURNAL OF BIOLOGICAL CHEMISTRY, 277 (3). pp. 2176-2185. ISSN 0021-9258

Bailey, L., Wienke, D., Howard, M., Knauper, V., Isacke, C. M., Murphy, G. (2002) Investigation of the role of Endo180/urokinase-type plasminogen activator receptor-associated protein as a collagenase 3 (matrix metalloproteinase 13) receptor. BIOCHEMICAL JOURNAL, 363 (1). pp. 67-72. ISSN 0264-6021

Tenev, T., Zachariou, A., Wilson, R., Paul, A., Meier, P. (2002) Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1. EMBO JOURNAL, 21 (19). pp. 5118-5129. ISSN 0261-4189

Geisler J, Dowsett M, Lonning PE (2002) Letrozole is more effective than anastrozole in suppressing total body aromatization and plasma strogen levels in postmenopausal breast cancer patients. AMERICAN JOURNAL OF ONCOLOGY REVIEWS, 1 . pp. 99-102.

East L, Isacke CM (2002) The mannose receptor family. BIOCHIMICA ET BIOPHYSICA ACTA, 1572 . pp. 364-386. ISSN 0006-3002

Legg JW, Lewis CA, Parsons M, Ng T, Isacke CM (2002) A novel PKC-regulated mechanism controls CD44-ezrin association and directional cell motility. NATURE CELL BIOLOGY, 4 (6). pp. 399-407. ISSN 1465-7392

Lakhani SR, van de Vijver MJ, Jacquemier J, Anderson TJ, Osin PP, McGuffog L, Easton DF (2002) The pathology of familial breast cancer: Predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2. JOURNAL OF CLINICAL ONCOLOGY, 20 (9). pp. 2310-2318. ISSN 0732-183X

Kenny, P. A., Enver, T., Ashworth, A. (2002) Retroviral vectors for establishing tetracycline-regulated gene expression in an otherwise recalcitrant cell line. BMC MOLECULAR BIOLOGY, 3 . ISSN 1471-2199

Brown, R. S. D., Edwards, J., Bartlett, J. W., Jones, C., Dogan, A. (2002) Routine acid decalcification of bone marrow samples can preserve DNA for FISH and CGH studies in metastatic prostate cancer. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 50 (1). pp. 113-115. ISSN 0022-1554

Warren, M., Smith, A., Partridge, N., Masabanda, J., Griffin, D., Ashworth, A. (2002) Structural analysis of the chicken BRCA2 gene facilitates identification of functional domains and disease causing mutations. HUMAN MOLECULAR GENETICS, 11 (7). pp. 841-851. ISSN 0964-6906

Sawyer EJ, Hanby AM, Rowan AJ, Gillett CE, Thomas RE, Poulsom R, Lakhani SR, Ellis IO, Ellis P, Tomlinson IP (2002) The Wnt pathway epithelial-stromal interactions and malignant progression in phyllodes tumours. JOURNAL OF PATHOLOGY, 196 (4). pp. 437-444. ISSN 0022-3417

Lewis, C. A., Townsend, P. A., Isacke, C. M. (2001) Ca2+/calmodulin-dependent protein kinase mediates the phosphorylation of CD44 required for cell migration on hyaluronan. BIOCHEMICAL JOURNAL, 357 (Part 3). pp. 843-850. ISSN 0264-6021

Jones, C., Nonni, A. V., Fulford, L., Merrett, S., Chaggar, R., Eusebi, V., Lakhani, S. R. (2001) CGH analysis of ductal carcinoma of the breast with basaloid/myoepithelial cell differentiation. BRITISH JOURNAL OF CANCER, 85 (3). pp. 422-427. ISSN 0007-0920

Virgintino D, Robertson D, Errede M, Benagiano V, Bertossi M, Ambrosi G, Roncali L (2001) Expression of the gap junction protein connexin43 in human telencephalon microvessels. MICROVASCULAR RESEARCH, 62 (3). pp. 435-439. ISSN 0026-2862

Benagiano V, Roncali L, Virgintino D, Flace P, Errede M, Rizzi A, Girolamo F, Robertson D, Bormann J, Ambrosi G (2001) GABA immunoreactivity in the human cerebellar cortex: A light and electron microscopical study. HISTOCHEMICAL JOURNAL, 33 (9—10). pp. 537-543. ISSN 0018-2214

Stone, J. G., Robertson, D., Houlston, R. S. (2001) Immunohistochemistry for MSH2 and MHL1: a method for identifying mismatch repair deficient colorectal cancer. JOURNAL OF CLINICAL PATHOLOGY, 54 (6). pp. 484-487. ISSN 0021-9746

Monaghan P, Watson PR, Cook H, Scott L, Wallis TS, Robertson D (2001) An improved method for preparing thick sections for immuno/histochemistry and confocal microscopy and its use to identify rare events. JOURNAL OF MICROSCOPY-OXFORD, 203 (Part 2). pp. 223-226. ISSN 0022-2720

Hostein, I., Robertson, D., Di Stefano, D., Workman, P., Clarke, P. A. (2001) Inhibition of signal transduction by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin results in cytostasis and apoptosis. CANCER RESEARCH, 61 (10). pp. 4003-4009. ISSN 0008-5472

Smith, D. P., Rayter, S. I., Niederlander, C., Spicer, J., Jones, C. M., Ashworth, A. (2001) LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1. HUMAN MOLECULAR GENETICS, 10 (25). pp. 2869-2877. ISSN 0964-6906

Leonard, N., Chaggar, R., Jones, C., Takahashi, M., Nikitopoulou, A., Lakhani, S. R. (2001) Loss of heterozygosity at cylindromatosis gene locus, CYLD, in sporadic skin adnexal tumours. JOURNAL OF CLINICAL PATHOLOGY, 54 (9). pp. 689-692. ISSN 0021-9746

Lakhani, S. R., O'Hare, M. J. (2001) The mammary myoepithelial cell - Cinderella or ugly sister? BREAST CANCER RESEARCH, 3 (1). pp. 1-4. ISSN 1465-5411

Lyons, P. A., Armitage, N., Lord ,C. J., Phillips, M. S., Todd, J. A., Peterson, L. B., Wicker, L. S. (2001) Mapping by genetic interaction - High-resolution congenic mapping of the type 1 diabetes loci Idd10 and Idd18 in the NOD mouse. DIABETES, 50 (11). pp. 2633-2637. ISSN 0012-1797

Jones, C., Damiani, S., Wells, D., Chaggar, R., Lakhani, S. R., Eusebi, V. (2001) Molecular cytogenetic comparison of apocrine hyperplasia and apocrine carcinoma of the breast. AMERICAN JOURNAL OF PATHOLOGY, 158 (1). pp. 207-214. ISSN 0002-9440

Ralleigh G, Walker AE, Hall-Craggs MA, Lakhani SR, Saunders C (2001) MR imaging of the skin and nipple of the breast: differentiation between tumour recurrence and post-treatment change. EUROPEAN JOURNAL OF RADIOLOGY, 11 (9). pp. 1651-1658. ISSN 0720-048X

Tutt, A., Bertwistle, D., Valentine, J., Gabriel, A., Swift, S., Ross, G., Griffin, C., Thacker, J., Ashworth, A. (2001) Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences. EMBO JOURNAL, 20 (17). pp. 4704-4716. ISSN 0261-4189

Lakhani, S. R., O'Hare, M. J., Ashworth, A. (2001) Profiling familial breast cancer. Microarray analysis can be used to differentiate gene expression patterns between various types of tumors, including breast tumors caused by BRAC1 and BRAC2 mutations. But what must be done before technology can be used in the clinic? NATURE MEDICINE, 7 (4). pp. 408-410. ISSN 1078-8956

Perry, J., Palmer, S., Gabriel, A., Ashworth, A. (2001) A short pseudoautosomal region in laboratory mice. GENOME RESEARCH, 11 (11). pp. 1826-1832. ISSN 1088-9051

Book

Zvelebil, M., Baum, J. (2007) Understanding bioinformatics. Garland Science Textbooks. ISBN 978-081534024-9

UNSPECIFIED, ed. (2001) Biopsy Pathology of the Breast (2nd ed.). Biopsy Pathology . Arnold, London. ISBN 978-034075876-2

Book Section

Winer EP, Carey LA, Dowsett M, Tripathy D (2005) Beyond Anatomic Staging: Are We Ready to Take the Leap to Molecular Classification? In: American Society of Clinical Oncology Educational Book 2005. American Society of Clinical Oncology, pp. 46-59.

Dowsett, M. (2005) Biology of estrogen-dependent breast cancer (Chapter 1). In: Aromatase Inhibitors for the Treatment of Breast Cancer. CMP HealthCare Media, Manhasset, New York, USA, pp. 1-13.

Dowsett M, Garber J (2004) Aromatase Inhibitors as Chemopreventives of Breast Cancer. In: Cancer Chemoprevention Volume 1: Promising Cancer Chemopreventive Agents. Cancer Drug Discovery and Development . Humana Press, Totowa, USA, pp. 231-244. ISBN 978-158829076-2

Dowsett M (2004) Clinical trials with aromatase inhibitors for the prevention of breast cancer. In: Advances in Endocrine Therapy of Breast Cancer. Informa Healthcare, New York, USA, pp. 189-202. ISBN 978-082472228-9

Shenton K, Dowsett M, Dukes M (2002) Clinical Utility of Aromatase Inhibitors. In: Hormone Therapy in Breast and Prostate Cancer. Cancer Drug Discovery and Development . Humana Press, Totowa, USA, pp. 265-292. ISBN 978-089603673-4

Fulford L, Ryan DA, Lakhani SR. (2002) Pathology of breast cancer. In: UNSPECIFIED, (ed.) International Handbook of Breast Cancer. Euromed Communications Ltd.

Lakhani SR, Flanagan AM. (2002) Pathology of the breast and ovary in mutation carriers. In: UNSPECIFIED, (ed.) Familial Breast and Ovarian Cancer. Cambridge University Press, Cambridge, UK, pp. 108-124. ISBN 978-052180373-1

Lakhani SR, Dogan A. (2002) Wound healing. In: UNSPECIFIED, (ed.) Clinical Surgery in General (4th ed.). Churchill Livingstone, London, UK, pp. 322-330. ISBN 978-044307262-8

Dowsett M (2001) Aromatase inhibition: the outcome of twenty years of drug development. In: Aromatase Inhibition and Breast Cancer. Informa Healthcare, New York, USA, pp. 3-15. ISBN 978-082470412-4

Harper-Wynne C, Dowsett M (2001) Evidentiary basis for breast cancer prevention. In: The Effective Management of Breast Cancer. UK Key Advances in Clinical Practice Series . Aesculapius Medical Press, London, pp. 29-44. ISBN 978-190304413-1

Johston SRD, Smith IE, Dowsett M (2001) Place of aromatase inhibitors in the endocrine therapy of breast cancer. In: Aromatase Inhibition and Breast Cancer. Informa Healthcare, New York, USA, pp. 29-49. ISBN 978-082470412-4

Correction

Clayton H, Titley I, Vivanco MD (2004) Growth and differentiation of progenitor/stem cells derived from the human mammary gland (vol 297, pg 444, 2004). [Correction]

Alvi, A. J., Clayton, H., Joshi, C., Enver, T., Ashworth, A., Vivanco, M. D., Dale, T. C., Smalley, M. J. (2003) Functional and molecular characterisation of mammary side population cells (vol 5, pg R1, 2003). [Correction]

Editorial

Hall, P. A., Reis-Filho, J. S., Tomlinson, I. P. M., Poulsom, R. (2010) An introduction to genes, genomes and disease. [Editorial]

Ashworth, A. (2009) Familial breast cancer: the first linkage. [Editorial]

Watkins, N. A., Gusnanto, A., de Bono, B., De, S., Miranda-Saavedra, D., Hardie, D. L., Angenent, W. G. J., Attwood, A. P., Ellis, P. D., Erber, W., Foad, N. S., Garner, S. F., Isacke, C. M., Jolley, J., Koch, K., Macaulay, I. C., Morley, S. L., Rendon, A., Rice, K. M., Taylor, N., Thijssen-Timmer, D. C., Tijssen, M. R., van der Schoot, C. E., Wernisch, L., Winzer, T., Dudbridge, F., Buckley, C. D., Langford, C. F., Teichmann, S., Gottgens, B., Ouwehand, W. H., Bloodomics Consortium, [Group Author] (2009) A HaemAtlas: characterizing gene expression in differentiated human blood cells. [Editorial]

Bianchi, K., Jost, P. J., Kaufmann, T., Rutkowski, R. (2009) International EMBO workshop on `model organisms in cell death research', Obergurgl (Austria). [Editorial]

Dowsett, M. (2009) The potential of new technologies/approaches. Introduction to Sessions 3 and 4. [Editorial]

Alexander, C. M., Puchalski, J., Klos, K. S., Badders, N., Ailles, L., Kim, C. F., Dirks, P., Smalley, M. J. (2009) Separating Stem Cells by Flow Cytometry: Reducing Variability for Solid Tissues. [Editorial]

Smalley, M. J., Reis-Filho, J. S., Ashworth, A. (2008) BRCa1 and stem cells: tumour typecasting. [Editorial]

Reis-Filho, J. S., Lakhani, S. R. (2008) Breast cancer special types: why bother? [Editorial]

Tan, D. S. P., Lambros, M. B. K., Marchio, C., Reis-Filho, J. S. (2008) ESR1 amplification in endometrial carcinomas: hope or hyperbole? [Editorial]

Dowsett, M. (2008) Introduction to sessions on 'Predicting personal risk for breast cancer'. [Editorial]

Kilburn, L. S., T.N.T. Trial Management Group, [Group Author] (2008) 'Triple negative' breast cancer: a new area for phase III breast cancer clinical trials. [Editorial]

Stebbing, J., Crook, T. (2007) Cytotoxic-free treatment designs: time to resistance. [Editorial]

Dowsett, M., Miller, W. R. (2007) Introduction to sessions on Personalising treatment. [Editorial]

Meier, P., Vousden, K. H. (2007) Lucifer's labyrinth - Ten years of path finding in cell death. [Editorial]

Pinder, S. E., Reis-Filho, J. S. (2007) Non-operative breast pathology. [Editorial]

Lord, C. J., Ashworth, A. (2007) RAD51, BRCA2 and DNA repair: a partial resolution. [Editorial]

Ashworth, A., Rahman, N. (2006) Introduction. [Editorial]

Come, S. E., Buzdar, A. U., Ingle, J. N., Arteaga, C. L., Brown, M., Dowsett, M., Hilsenbeck, S. G., Kumar, R., Johnston, S. R. D., Lee, A. V., Paik, S., Pritchard, K. I., Winer, E. P., Hart, C. (2006) Proceedings of the Fifth International Conference on Recent Advances and Future Directions in Endocrine Therapy for Breast Cancer: Conference summary statement. [Editorial]

Sowter, H. M., Ashworth, A. (2005) BRCA1 and BRCA2 as ovarian cancer susceptibility genes. [Editorial]

Ditzel, M., Meier, P. (2005) Ubiquitylation in apoptosis: DIAP1's (N-)en(d)igma. [Editorial]

Spicer J, Ashworth A (2004) LKB1 kinase: Master and commander of metabolism and polarity. [Editorial]

Rahman N, Ashworth A (2004) A new gene on the X involved in Fanconi anemia. [Editorial]

Lakhani SR (2004) Putting the brakes on cylindromatosis? [Editorial]

Thorne, R. F., Legg, J. W., Isacke, C. M. (2004) The role of the CD44 transmembrane and cytoplasmic domains in co-ordinating adhesive and signalling events. [Editorial]

Tutt A, Ashworth A (2003) Close relatives or distant cousins? [Editorial]

Lakhani, S. R. (2003) The diagnosis and management of pre-invasive breast disease - current challenges, future hopes. [Editorial]

Lakhani SR (2003) In-situ lobular neoplasia: time for an awakening. [Editorial]

Dowsett M, Ashworth A (2003) New biology of the oestrogen receptor. [Editorial]

Stone C, McCabe N, Ashworth A (2003) X-chromosome inactivation: X marks the spot for BRCA1. [Editorial]

Witt E, Ashworth A (2002) Biomedicine - D-Day for BRCA2. [Editorial]

Lakhani S, Ashworth A (2001) Microarray and histopathological analysis of tumours: the future and the past?. [Editorial]

Letter

Dowsett, M. (2010) Absolute Benefits of Aromatase Inhibitors in Adjuvant Treatment of Breast Cancer: Should We Know More? Reply to B. Seruga et al. [Letter]

Hughes, A. E., Orr, N., Cordell, H. J., Goodship, T. (2010) Associations of CFHR1-CFHR3 deletion and a CFH snp to age-related macular degeneration are not independent reply. [Letter]

Lonning, P. E., Dowsett, M. (2010) Endocrine Effects of Aromatase Inhibitors. [Letter]

Del Giudice, I., Osuji, N., Dexter, T., Brito-Babapulle, V., Parry-Jones, N., Chiaretti, S., Messina, M., Morgan, G., Catovsky, D., Matutes, E. (2009) B-cell prolymphocytic leukemia and chronic lymphocytic leukemia have distinctive gene expression signatures. [Letter]

Reynolds, A. R., Hodivala-Dilke, K. M. (2009) Will integrin inhibitors have proangiogenic effects in the clinic? Reply. [Letter]

Hatzimichael, E., Dasoula, A., Benetatos, L., Makis, A., Stebbing, J., Crook, T., Syrrou, M., Bourantas, K. L. (2008) The absence of CDKN1C (p57KIP2) promoter methylation in myeloid malignancies also characterizes plasma cell neoplasms. [Letter]

Rakha, E., Ellis, I., Reis-Filho, J. (2008) Are triple-negative and basal-like breast cancer synonymous? [Letter]

Reis-Filho, J. S., Drury, S., Lambros, M. B., Marchio, C., Johnson, N., Natrajan, R., Salter, J., Levey, P., Fletcher, O., Peto, J., Ashworth, A., Dowsett, M. (2008) ESR1 gene amplification in breast cancer: a common phenomenon? [Letter]

Lindeman, G. J., Visvader, J. E., Smalley, M. J., Eaves, C. J. (2008) The future of mammary stem cell biology: the power of in vivo transplants. [Letter]

Rakha, E. A., Ellis, I. O., Reis-Filho, J. S. (2008) Immunohistochemical heterogeneity of breast carcinomas negative for estrogen receptors, progesterone receptors and Her2/neu (basal-like breast carcinomas). [Letter]

Benetatos, L., Dasoula, A., Syed, N., Hatzimichael, E., Crook, T., Bourantas, K. L. (2008) Methylation analysis of the von Hippel-Lindau gene in acute myeloid leukaemia and myelodysplastic syndromes. [Letter]

Rakha, E. A., Tan, D. S. P., Foulkes, W. D., Ellis, I. O., Tutt, A., Nielsen, T. O., Reis-Filho, J. S. (2007) Are triple-negative tumours and basal-like breast cancer synonymous? [Letter]

Cleator, S., Makris, A., Powles, T. (2006) Response to letter "Analysis of breast cancer survival by clinical response to neoadjuvant chemoendocrine therapy" by Bogaerts et al. (Ann Oncol 2006; 17 : 352-353). [Letter]

Pierga, J. Y., Reis-Filho, J. S. (2005) Ewing's sarcoma of the rectum: Can we afford not to use molecular pathology? [Letter]

Reis-Filho JS (2005) Re: Korsching et al. The origin of vimentin expression in invasive breast cancer: epithelial-mesenchymal transition, myoepithelial histogenesis or histogenesis from progenitor cells with bilinear differentiation potential? J Pathol 2005; 206: 451-457. [Letter]

Ashworth A (2004) Refocusing on BRCA1. [Letter]

Lakhani, S. (2003) The diagnosis and management of pre-invasive breast disease: editor's reply. [Letter]

Jones C, Tooze R, Lakhani SR (2003) Malignant adenomyoepithelioma of the breast metastasizing to the liver. [Letter]

Reis-Filho JS (2003) Primary salivary clear cell tumors. [Letter]

Reis-Filho JS (2003) Re: Sastre-Garau et al. Inflammatory myofibroblastic tumour (inflammatory pseudotumour) of the breast: clinicopathological and genetic analysis of a case with evidence for clonality. J Pathol 2002; 196 : 97-102. [Letter]

Monograph

Henderson C, Piccart MJ, Baum M, Berry DA, Coombes RC, Dowsett M, Howell A, Ingle JN, Jänicke F, Kaufmann M, Pritchard KI, Rose C, Tu D, Winer EP (2004) The evolving role of aromatase inhibitors in adjuvant breast cancer therapy. Other. UNKNOWN.

Review Article

Marchio, C., Weigelt, B., Reis-Filho, J. S. (2010) Adenoid cystic carcinomas of the breast and salivary glands (or 'The strange case of Dr Jekyll and Mr Hyde' of exocrine gland carcinomas). JOURNAL OF CLINICAL PATHOLOGY, 63 (3). pp. 220-228. ISSN 0021-9746

Fletcher, O., Houlston, R. S. (2010) Architecture of inherited susceptibility to common cancer. NATURE REVIEWS CANCER, 10 (5). pp. 353-361. ISSN 1474-175X

Moore, A. S., Blagg, J., Linardopoulos, S., Pearson, A. D. J. (2010) Aurora kinase inhibitors: novel small molecules with promising activity in acute myeloid and Philadelphia-positive leukemias. LEUKEMIA, 24 (4). pp. 671-678. ISSN 0887-6924

Lord, C. J., Ashworth, A. (2010) Biology-driven cancer drug development: back to the future. BMC BIOLOGY, 8 . ISSN 1741-7007

Rakha, E. A., Reis-Filho, J. S., Ellis, I. O. (2010) Combinatorial biomarker expression in breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 120 (2). pp. 293-308. ISSN 0167-6806

Weigelt, B., Baehner, F. L., Reis-Filho, J. S. (2010) The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade. JOURNAL OF PATHOLOGY, 220 (2). pp. 263-280. ISSN 0022-3417

Shiu, K., Natrajan, R., Geyer, F. C., Ashworth, A., Reis-Filho, J. S. (2010) DNA amplifications in breast cancer: genotypic-phenotypic correlations. FUTURE ONCOLOGY, 6 (6). pp. 967-984. ISSN 1479-6694

Turner, N., Grose, R. (2010) Fibroblast growth factor signalling: from development to cancer. NATURE REVIEWS CANCER, 10 (2). pp. 116-129. ISSN 1474-175X

Martin, S. A., Hewish, M., Lord, C. J., Ashworth, A. (2010) Genomic instability and the selection of treatments for cancer. JOURNAL OF PATHOLOGY, 220 (2). pp. 281-289. ISSN 0022-3417

Weigelt, B., Geyer, F. C., Reis-Filho, J. S. (2010) Histological types of breast cancer: How special are they? MOLECULAR ONCOLOGY, 4 (3). pp. 192-208. ISSN 1574-7891

Gyrd-Hansen, M., Meier, P. (2010) IAPs: from caspase inhibitors to modulators of NF-kappa B, inflammation and cancer. NATURE REVIEWS CANCER, 10 (8). pp. 561-574. ISSN 1474-175X

Hewish, M., Lord, C. J., Martin, S. A., Cunningham, D., Ashworth, A. (2010) Mismatch repair deficient colorectal cancer in the era of personalized treatment. NATURE REVIEWS CLINICAL ONCOLOGY, 7 (4). pp. 197-208. ISSN 1759-4774

Rakha, E., Reis-Filho, J. S. (2009) Basal-like Breast Carcinoma From Expression Profiling to Routine Practice. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE, 133 (6). pp. 860-868. ISSN 0003-9985

Lopez, J., Percharde, M., Coley, H. M., Webb, A., Crook, T. (2009) The context and potential of epigenetics in oncology. BRITISH JOURNAL OF CANCER, 100 (4). pp. 571-577. ISSN 0007-0920

Penault-Llorca, F., Bilous, M., Dowsett, M., Hanna, W., Osamura, R. Y., Rueschoff, J., van de Vijver, M. (2009) Emerging Technologies for Assessing HER2 Amplification. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 132 (4). pp. 539-548. ISSN 0002-9173

Geyer, F. C., Lopez-Garcia, M. A., Lambros, M. B., Reis-Filho, J. S. (2009) Genetic characterization of breast cancer and implications for clinical management. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 13 (10). pp. 4090-4103. ISSN 1582-1838

Weigelt, B., Reis-Filho, J. S. (2009) Histological and molecular types of breast cancer: is there a unifying taxonomy? NATURE REVIEWS CLINICAL ONCOLOGY, 6 (12). pp. 718-730. ISSN 1759-4774

Geyer, F. C., Reis-Filho, J. S. (2009) Microarray-based Gene Expression Profiling as a Clinical Tool for Breast Cancer Management: Are We There Yet? INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY, 17 (4). pp. 285-302. ISSN 1066-8969

Rakha, E. A., El-Sayed, M. E., Reis-Filho, J., Ellis, I. O. (2009) Patho-biological aspects of basal-like breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 113 (3). pp. 411-422. ISSN 0167-6806

Geyer, F. C., Marchio, C., Reis-Filho, J. S. (2009) The role of molecular analysis in breast cancer. PATHOLOGY, 41 (1). pp. 77-88. ISSN 0031-3025

Bianchi, K., Meier, P. (2009) A Tangled Web of Ubiquitin Chains: Breaking News in TNF-R1 Signaling. MOLECULAR CELL, 36 (5). pp. 736-742. ISSN 1097-2765

Broemer, M., Meier, P. (2009) Ubiquitin-mediated regulation of apoptosis. TRENDS IN CELL BIOLOGY, 19 (3). pp. 130-140. ISSN 0962-8924

Leary, A. F., Hanna, W. M., van de Vijver, M. J., Penault-Llorca, F., Ruschoff, J., Osamura, R. Y., Bilous, M., Dowsett, M. (2009) Value and Limitations of Measuring HER-2 Extracellular Domain in the Serum of Breast Cancer Patients. JOURNAL OF CLINICAL ONCOLOGY, 27 (10). pp. 1694-1705. ISSN 0732-183X

Savage, P., Stebbing, J., Bower, M., Crook, T. (2009) Why does cytotoxic chemotherapy cure only some cancers? NATURE CLINICAL PRACTICE ONCOLOGY, 6 (1). pp. 43-52. ISSN 1743-4254

Rakha, E. A., Reis-Filho, J. S., Ellis, I. O. (2008) Basal-like breast cancer: A critical review. JOURNAL OF CLINICAL ONCOLOGY, 26 (15). pp. 2568-2581. ISSN 0732-183X

Tan, D. S. R., Reis-Filho, J. S. (2008) Comparative genomic hybridisation arrays: High-throughput tools to determine targeted therapy in breast cancer. PATHOBIOLOGY, 75 (2). pp. 63-74. ISSN 1015-2008

Shiu, K. K., Tan, D. S. P., Reis-Filho, J. S. (2008) Development of therapeutic approaches to 'triple negative' phenotype breast cancer. EXPERT OPINION ON THERAPEUTIC TARGETS, 12 (9). pp. 1123-1137. ISSN 1472-8222

Martin, S. A., Lord, C. J., Ashworth, A. (2008) DNA repair deficiency as a therapeutic target in cancer. CURRENT OPINION IN GENETICS & DEVELOPMENT, 18 (1). pp. 80-86. ISSN 0959-437X

Ashworth, A. (2008) Drug Resistance Caused by Reversion Mutation. CANCER RESEARCH, 68 (24). pp. 10021-10023. ISSN 0008-5472

Rakha, E. A., El-Sayed, M. E., Reis-Filho, J. S., Ellis, I. O. (2008) Expression profiling technology: its contribution to our understanding of breast cancer. HISTOPATHOLOGY, 52 (1). pp. 67-81. ISSN 0309-0167

Tan, D. S. P., Marchio, C., Reis-Filho, J. S. (2008) Hereditary breast cancer: from molecular pathology to tailored therapies. JOURNAL OF CLINICAL PATHOLOGY, 61 (10). pp. 1073-1082. ISSN 0021-9746

Rakha, E. A., Reis-Filho, J. S., Ellis, I. O. (2008) Impact of basal-like breast carcinoma determination for a more specific therapy. PATHOBIOLOGY, 75 (2). pp. 95-103. ISSN 1015-2008

Turner, N. C., Jones, A. L. (2008) Management of breast cancer - Part I. BRITISH MEDICAL JOURNAL, 337 (7661). pp. 107-110. ISSN 0007-1447

Turner, N. C., Jones, A. L. (2008) Management of breast cancer - Part II. BRITISH MEDICAL JOURNAL, 337 (7662). pp. 164-169. ISSN 0007-1447

Lord, C. J., Ashworth, A. (2008) Targeted therapy for cancer using PARP inhibitors. CURRENT OPINION IN PHARMACOLOGY, 8 (4). pp. 363-369. ISSN 1471-4892

Kendrick, H., Regan, J. L., Magnay, F. A., Grigoriadis, A., Mitsopoulos, C., Zvelebil, M., Smalley, M. J. (2008) Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate. BMC GENOMICS, 9 . ISSN 1471-2164

Reis-Filho, J. S., Tutt, A. N. J. (2008) Triple negative tumours: a critical review. HISTOPATHOLOGY, 52 (1). pp. 108-118. ISSN 0309-0167

Lambros, M. B. K., Natrajan, R., Reis-Filho, J. S. (2007) Chromogenic and fluorescent in situ hybridization in breast cancer. HUMAN PATHOLOGY, 38 (8). pp. 1105-1122. ISSN 0046-8177

Tan, D. S. P., Lambros, M. B. K., Natrajan, R., Reis-Filho, J. S. (2007) Getting it right: designing microarray (and not 'microawry') comparative genomic hybridization studies for cancer research. LABORATORY INVESTIGATION, 87 (8). pp. 737-754. ISSN 0023-6837

Pinder, S. E., Provenzano, E., Reis-Filho, J. S. (2007) Lobular in situ neoplasia and columnar cell lesions: diagnosis in breast core biopsies and implications for management. PATHOLOGY, 39 (2). pp. 208-216. ISSN 0031-3025

Molyneux, G., Regan, J., Smalley, M. J. (2007) Mammary stem cells and breast cancer. CMLS-Cellular and Molecular Life Sciences, 64 (24). pp. 3248-3260. ISSN 1420-682X

Banerjee, S., Dowsett, M., Ashworth, A., Martin, L. A. (2007) Mechanisms of Disease: angiogenesis and the management of breast cancer. NATURE CLINICAL PRACTICE ONCOLOGY, 4 (9). pp. 536-550. ISSN 1743-4254

Panchal, H., Wansbury, O., Parry, S., Ashworth, A., Howard, B. (2007) Neuregulin3 alters cell fate in the epidermis and mammary gland. BMC DEVELOPMENTAL BIOLOGY, 7 . ISSN 1471-213X

Britt, K., Ashworth, A., Smalley, M. (2007) Pregnancy and the risk of breast cancer. ENDOCRINE-RELATED CANCER, 14 (4). pp. 907-933. ISSN 1351-0088

Regan, J., Smalley, M. (2007) Prospective isolation and functional analysis of stem and differentiated cells from the mouse mammary gland. STEM CELL REVIEWS, 3 (2). pp. 124-136. ISSN 1550-8943

Iorns, E., Lord, C. J., Turner, N., Ashworth, A. (2007) Utilizing RNA interference to enhance cancer drug discovery. NATURE REVIEWS DRUG DISCOVERY, 6 (7). pp. 556-568. ISSN 1474-1776

Turner, N. C., Reis-Filho, J. S. (2006) Basal-like breast cancer and the BRCA1 phenotype. ONCOGENE, 25 (43). pp. 5846-5853. ISSN 0950-9232

Stebbing, J., Bower, M., Syed, N., Smith, P., Yu, V., Crook, T. (2006) Epigenetics: an emerging technology in the diagnosis and treatment of cancer. PHARMACOGENOMICS, 7 (5). pp. 747-757. ISSN 1462-2416

Reis-Filho, J. S., Westbury, C., Pierga, J. Y. (2006) The impact of expression profiling on prognostic and predictive testing in breast cancer. JOURNAL OF CLINICAL PATHOLOGY, 59 (3). pp. 225-231. ISSN 0021-9746

Dua, R. S., Isacke, C. M., Gui, G. P. H. (2006) The intraductal approach to breast cancer biomarker discovery. JOURNAL OF CLINICAL ONCOLOGY, 24 (7). pp. 1209-1216. ISSN 0732-183X

Gudmundsdottir, K., Ashworth, A. (2006) The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability. ONCOGENE, 25 (43). pp. 5864-5874. ISSN 0950-9232

Howard, B., Ashworth, A. (2006) Signalling pathways implicated in early mammary gland morphogenesis and breast cancer. PLOS GENETICS, 2 (8). pp. 1121-1130. ISSN 1553-7390

Simpson PT, Reis-Filho JS, Gale T, Lakhani SR (2005) Molecular evolution of breast cancer. JOURNAL OF PATHOLOGY, 205 (2). pp. 248-254. ISSN 0022-3417

Reis-Filho JS, Simpson PT, Gale T, Lakhani SR (2005) The molecular genetics of breast cancer: The contribution of comparative genomic hybridization. PATHOLOGY, RESEARCH AND PRACTICE, 201 (11). pp. 713-725. ISSN 0344-0338

Ashworth A (2005) Oh what a tangled web it weaves: BRCA1 and DNA decatenation. CANCER CELL, 8 (2). pp. 95-97. ISSN 1535-6108

Fletcher, O., Gibson, L., Johnson, N., Altmann, D. R., Holly, J. M. P., Ashworth, A., Peto, J., Silva, I. D. (2005) Polymorphisms and circulating levels in the insulin-like growth factor system and risk of breast cancer: A systematic review. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 14 (1). pp. 2-19. ISSN 1055-9965

Turner, N., Tutt, A., Ashworth, A. (2004) Hallmarks of 'BRCAness' in sporadic cancers. NATURE REVIEWS CANCER, 4 (10). pp. 814-819. ISSN 1474-175X

Santarosa M, Ashworth A (2004) Haploinsufficiency for tumour suppressor genes: when you don't need to go all the way. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 1654 (2). pp. 105-122. ISSN 0304-419X

Cleator, S., Ashworth, A. (2004) Molecular profiling of breast cancer: clinical implications. BRITISH JOURNAL OF CANCER, 90 (6). pp. 1120-1124. ISSN 0007-0920

Saunders Y, Ross JR, Broadley KE, Edmonds PM, Patel S, on behalf of Steering Group (includes Dearnaley D, Dowsett M, Ahern R, Powles T, Johnston S) (2004) Systematic review of bisphosphonates for hypercalcaemia of malignancy. PALLIATIVE MEDICINE, 18 (5). pp. 418-431. ISSN 0269-2163

Deniz K, O'Mahony S, Ross G, Purushotham A (2003) Breast cancer in women after treatment for Hodgkin's disease. LANCET ONCOLOGY, 4 (4). pp. 207-214. ISSN 1470-2045

Schmitt, F. C,. Reis-Filho, J. S. (2003) c-myc, not her-2/neu, can predict the prognosis of breast cancer patients: how novel, how accurate, and how significant? BREAST CANCER RESEARCH, 5 (4). pp. 188-191. ISSN 1465-5411

Reis-Filho, J. S., Lakhani, S. R. (2003) The diagnosis and management of pre-invasive breast disease - Genetic alterations in pre-invasive lesions. BREAST CANCER RESEARCH, 5 (6). pp. 313-319. ISSN 1465-5411

Simpson, P. T., Gale, T., Fulford, L. G., Reis-Filho, J. S., Lakhani, S. R. (2003) The diagnosis and management of pre-invasive breast disease - Pathology of atypical lobular hyperplasia and lobular carcinoma in situ. BREAST CANCER RESEARCH, 5 (5). pp. 258-262. ISSN 1465-5411

Pia-Foschini, M., Reis-Filho, J. S., Eusebi, V., Lakhani, S. R. (2003) Salivary gland-like tumours of the breast: surgical and molecular pathology. JOURNAL OF CLINICAL PATHOLOGY, 56 (7). pp. 497-506. ISSN 0021-9746

Smalley M, Ashworth A (2003) Stem cells and breast cancer: A field in transit. NATURE REVIEWS CANCER, 3 (11). pp. 832-844. ISSN 1474-175X

Theodosiou, A., Ashworth, A. (2002) MAP kinase phosphatases. GENOME BIOLOGY, 3 (7). REVIEWS3009.1-REVIEWS3009.10. ISSN 1465-6906

Tutt A, Ashworth A (2002) The relationship between the roles of BRCA genes in DNA repair and cancer predisposition. TRENDS IN MOLECULAR MEDICINE, 8 (12). pp. 571-576. ISSN 1471-4914

Lakhani, S. R. (2001) Molecular genetics of solid tumours: translating research into clinical practice. What we could do now: breast cancer. JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY, 54 (5). pp. 281-284. ISSN 1366-8714

Kerr P, Ashworth A (2001) New complexities for BRAC1 and BRAC2. CURRENT BIOLOGY, 11 (16). R668-R676. ISSN 0960-9822

Smalley MJ, Dale TC (2001) Wnt signaling and mammary tumorigenesis. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, 6 (1). pp. 37-52. ISSN 1083-3021