Article

Jones, R. L., Salter, J., A'Hern, R., Nerurkar, A., Parton, M., Reis-Filho, J. S., Smith, I. E., Dowsett, M. (2010) Relationship between oestrogen receptor status and proliferation in predicting response and long-term outcome to neoadjuvant chemotherapy for breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 119 (2). pp. 315-323. ISSN 0167-6806

Dunbier, A. K., Anderson, H., Ghazoui, Z., Folkerd, E. J., A'Hern, R., Crowder, R. J., Hoog, J., Smith, I. E., Osin, P., Nerurkar, A., Parker, J. S., Perou, C. M., Ellis, M. J., Dowsett, M. (2010) Relationship Between Plasma Estradiol Levels and Estrogen-Responsive Gene Expression in Estrogen Receptor-Positive Breast Cancer in Postmenopausal Women. JOURNAL OF CLINICAL ONCOLOGY, 28 (7). pp. 1161-1167. ISSN 0732-183X

Rabaglio, M., Sun, Z., Price, K. N., Castiglione-Gertsch, M., Hawle, H., Thurlimann, B., Mouridsen, H., Campone, M., Forbes, J. F., Paridaens, R. J., Colleoni, M., Pienkowski, T., Nogaret, J. -., Lang, I., Smith, I., Gelber, R. D., Goldhirsch, A., Coates, A. S., Big 1-98 Collaborative Int Breast, [Group Author] (2009) Bone fractures among postmenopausal patients with endocrine-responsive early breast cancer treated with 5 years of letrozole or tamoxifen in the BIG 1-98 trial. ANNALS OF ONCOLOGY, 20 (9). pp. 1489-1498. ISSN 0923-7534

Arnedos, M., Nerurkar, A., Osin, P., A'Hern, R., Smith, I. E., Dowsett, M. (2009) Discordance between core needle biopsy (CNB) and excisional biopsy (EB) for estrogen receptor (ER), progesterone receptor (PgR) and HER2 status in early breast cancer (EBC). ANNALS OF ONCOLOGY, 20 (12). pp. 1948-1952. ISSN 0923-7534

Johnston, S. R. D. (2009) Enhancing the Efficacy of Hormonal Agents with Selected Targeted Agents. CLINICAL BREAST CANCER, 9 (Supplement 1). S28-S36. ISSN 1526-8209

Lambros, M. B. K., Tan, D. S. P., Jones, R. L., Vatcheva, R., Savage, K., Tamber, N., Fenwick, K., Mackay, A., Ashworth, A., Reis-Filho, J. S. (2009) Genomic profile of a secretory breast cancer with an ETV6-NTRK3 duplication. JOURNAL OF CLINICAL PATHOLOGY, 62 (7). pp. 604-612. ISSN 0021-9746

Sirohi, B., Leary, A., Johnston, S. R. D. (2009) Ipsilateral Breast Tumor Recurrence: Is There Any Evidence for Benefit of Further Systemic Therapy? THE BREAST JOURNAL, 15 (3). pp. 268-278. ISSN 1075-122X

Johnston, S., Pippen Jr., J., Pivot, X., Lichinitser, M., Sadeghi, S., Dieras, V., Gomez, H. L., Romieu, G., Manikhas, A., Kennedy, M. J., Press, M. F., Maltzman, J., Florance, A., O'Rourke, L., Oliva, C., Stein, S., Pegram, M. (2009) Lapatinib Combined With Letrozole Versus Letrozole and Placebo As First-Line Therapy for Postmenopausal Hormone Receptor-Positive Metastatic Breast Cancer. JOURNAL OF CLINICAL ONCOLOGY, 27 (33). pp. 5538-5546. ISSN 0732-183X

Kaufman, B., Trudeau, M., Awada, A., Blackwell, K., Bachelot, T., Salazar, V., DeSilvio, M., Westlund, R., Zaks, T., Spector, N., Johnston, S. (2009) Lapatinib monotherapy in patients with HER2-overexpressing relapsed or refractory inflammatory breast cancer: final results and survival of the expanded HER2+cohort in EGF103009, a phase II study. LANCET ONCOLOGY, 10 (6). pp. 581-588. ISSN 1470-2045

Mouridsen, H., Giobbie-Hurder, A., Goldhirsch, A., Thuerlimann, B., Paridaens, R., Smith, I., Mauriac, L., Forbes, J. F., Price, K. N., Regan, M. M., Gelber, R. D., Coates, A. S., Big 1-98 Collaborative Grp, [Group Author] (2009) Letrozole Therapy Alone or in Sequence with Tamoxifen in Women with Breast Cancer. NEW ENGLAND JOURNAL OF MEDICINE, 361 (8). pp. 766-776. ISSN 0028-4793

Jones, R. L., Salter, J., A'Hern, R., Nerurkar, A., Parton, M., Reis-Filho, J. S., Smith, I. E., Dowsett, M. (2009) The prognostic significance of Ki67 before and after neoadjuvant chemotherapy in breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 116 (1). pp. 53-68. ISSN 0167-6806

Jones, R. L., Walsh, G., Ashley, S., Chua, S., Agarwal, R., O'Brien, M., Johnston, S., Smith, I. E. (2009) A randomised pilot Phase II study of doxorubicin and cyclophosphamide (AC) or epirubicin and cyclophosphamide (EC) given 2 weekly with pegfilgrastim (accelerated) vs 3 weekly (standard) for women with early breast cancer. BRITISH JOURNAL OF CANCER, 100 (2). pp. 305-310. ISSN 0007-0920

Rixe, O., Franco, S. X., Yardley, D. A., Johnston, S. R., Martin, M., Arun, B. K., Letrent, S. P., Rugo, H. S. (2009) A randomized, phase II, dose-finding study of the pan-ErbB receptor tyrosine-kinase inhibitor CI-1033 in patients with pretreated metastatic breast cancer. CANCER CHEMOTHERAPY AND PHARMACOLOGY, 64 (6). pp. 1139-1148. ISSN 0344-5704

Ellis, P., Barrett-Lee, P., Johnson, L., Cameron, D., Wardley, A., O'Reilly, S., Verrill, M., Smith, I., Yarnold, J., Coleman, R., Earl, H., Canney, P., Twelves, C., Poole, C., Bloomfield, D., Hopwood, P., Johnston, S., Dowsett, M., Bartlett, J. M. S., Ellis, I., Peckitt, C., Hall, E., Bliss, J. M., TACT Trial Management Grp, [Group Author], TACT Trialists, [Group Author] (2009) Sequential docetaxel as adjuvant chemotherapy for early breast cancer (TACT): an open-label, phase III, randomised controlled trial. LANCET, 373 (9676). pp. 1681-1692. ISSN 0140-6736

Jahromi, A. H., Narayanan, S., MacNeill, F., Osin, P., Nerurkar, A., Gui, G. (2009) Testing the feasibility of intra-operative sentinel lymph node touch imprint cytology. ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND, 91 (4). pp. 336-339. ISSN 0035-8843

Banerjee, S., Pancholi, S., A'Hern, R., Ghazoui, Z., Smith, I. E., Dowsett, M., Martin, L. A. (2008) The effects of neoadjuvant anastrozole and tamoxifen on circulating vascular endothelial growth factor and soluble vascular endothelial growth factor receptor 1 in breast cancer. CLINICAL CANCER RESEARCH, 14 (9). pp. 2656-2663. ISSN 1078-0432

Come, S. E., Buzdar, A. U., Ingle, J. N., Johnston, S. R. D., Brodie, A. M., Coombes, R. C., Miller, W. R., Pritchard, K. I., Winer, E. P., Zujewski, J. A., Goss, P. E. (2008) Endocrine and Targeted Manipulation of Breast Cancer: Summary statement for the Sixth Cambridge Conference. CANCER, 112 (3). pp. 673-678. ISSN 0008-543X

Pancholi, S., Lykkesfeldt, A. E., Hilmi, C., Banerjee, S., Leary, A., Drury, S., Johnston, S., Dowsett, M., Martin, L. A. (2008) ERBB2 influences the subcellullar localization of the estrogen receptor in tamoxifen-resistant MCF-7 cells leading to the activation of AKT and RPS6KA2. ENDOCRINE-RELATED CANCER, 15 (4). pp. 985-1002. ISSN 1351-0088

Untch, M., Gelber, R. D., Jackisch, C., Procter, M., Baselga, J., Bell, R., Cameron, D., Bari, M., Smith, I., Leyland-Jones, B., de Azambuja, E., Wermuth, P., Khasanov, R., Feng-yi, F., Constantin, C., Mayordomo, J. I., Su, C. H., Yu, S. Y., Lluch, A., Senkus-Konefka, E., Price, C., Haslbauer, F., Sahui, T. S., Srimuninnimit, V., Colleoni, M., Coates, A. S., Piccart-Gebhart, M. J., Goldhirsch, A., HERA Study Team, [Group Author] (2008) Estimating the magnitude of trastuzumab effects within patient subgroups in the HERA trial. ANNALS OF ONCOLOGY, 19 (6). pp. 1090-1096. ISSN 0923-7534

Johnston, S. R. D. (2008) Integration of endocrine therapy with targeted agents. BREAST CANCER RESEARCH, 10 (Supplement 4). ISSN 1465-5411

Benson, J. R., della Rovere, G. Q. (2008) Ipsilateral breast cancer recurrence. BREAST, 17 (1). pp. 12-18. ISSN 0960-9776

Crivellari, D., Sun, Z., Coates, A. S., Price, K. N., Thurlimann, B., Mouridsen, H., Mauriac, L., Forbes, J. F., Paridaens, R. J., Castiglione-Gertsch, M., Gelber, R. D., Colleoni, M., Lang, I., Del Mastro, L., Gladieff, L., Rabaglio, M., Smith, I. E., Chirgwin, J. H., Goldhirsch, A. (2008) Letrozole compared with tamoxifen for elderly patients with endocrine-responsive early breast cancer: The BIG 1-98 trial. JOURNAL OF CLINICAL ONCOLOGY, 26 (12). pp. 1972-1979. ISSN 0732-183X

Gui, G. P. H., Kadayaprath, G., Tan, S. M., Faliakou, E. C., Choy, C., Ward, A., A'Hern, R. (2008) Long-term Quality-of-Life assessment following one-stage immediate breast reconstruction using biodimensional expander implants: The patient's perspective. PLASTIC AND RECONSTRUCTIVE SURGERY, 121 (1). pp. 17-24. ISSN 0032-1052

Smith, I. E. (2008) Neoadjuvant/presurgical treatments. BREAST CANCER RESEARCH, 10 (Supplement 4). ISSN 1465-5411

Ellis, M. J., Tao, Y., Luo, J. Q., A'Hern, R., Evans, D. B., Bhatnagar, A. S., Ross, H. A. C., von Kameke, A., Miller, W. R., Smith, I., Eiermann, W., Dowsett, M. (2008) Outcome prediction for estrogen receptor-positive breast cancer based on postneoadjuvant endocrine therapy tumor characteristics. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 100 (19). pp. 1380-1388. ISSN 0027-8874

Johnston, S., Trudeau, M., Kaufman, B., Boussen, H., Blackwell, K., LoRusso, P., Lombardi, D. P., Ben Ahmed, S., Citrin, D. L., DeSilvio, M. L., Harris, J., Westlund, R. E., Salazar, V., Zaks, T. Z., Spector, N. L. (2008) Phase II study of predictive biomarker profiles for response targeting human epidermal growth factor receptor 2 (HER-2) in advanced inflammatory breast cancer with lapatinib monotherapy. JOURNAL OF CLINICAL ONCOLOGY, 26 (7). pp. 1066-1072. ISSN 0732-183X

Johnston, S. R. D., Semiglazov, V. F., Manikhas, G. M., Spaeth, D., Romieu, G., Dodwell, D. J., Wardley, A. M., Neven, P., Bessems, A., Park, Y. C., De Porre, P. M., Ruixo, J. J. P., Howes, A. J. (2008) A phase II, randomized, blinded study of the farnesyltransferase inhibitor tipifarnib combined with letrozole in the treatment of advanced breast cancer after antiestrogen therapy. BREAST CANCER RESEARCH AND TREATMENT, 110 (2). pp. 327-335. ISSN 0167-6806

Sirohi, B., Arnedos, M., Popat, S., Ashley, S., Nerurkar, A., Walsh, G., Johnston, S., Smith, I. E. (2008) Platinum-based chemotherapy in triple-negative breast cancer. ANNALS OF ONCOLOGY, 19 (11). pp. 1847-1852. ISSN 0923-7534

Hughes, S., Barbachano, Y., Ashley, S., Yap, Y. S., Popat, S., Allen, M., Della-Rovere, U. Q., Johnston, S., Smith, I., O'Brien, M. (2008) Time trends in the outcome of elderly patients with breast cancer. THE BREAST JOURNAL, 14 (2). pp. 158-163. ISSN 1075-122X

Tan, D. S. P., Marchio, C., Jones, R. L., Savage, K., Smith, I. E., Dowsett, M., Reis, J. S. (2008) Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients. BREAST CANCER RESEARCH AND TREATMENT, 111 (1). pp. 27-44. ISSN 0167-6806

Smith, I. E. (2008) Which tools can I use in daily clinical practice to improve tailoring of treatment for breast cancer? Treatment decision-making in advanced disease. ANNALS OF ONCOLOGY, 19 (Supplement 7). pp. 51-57. ISSN 0923-7534

Smith, I., Procter, M. D. Gelber, R., Guillaume, S., Feyereislova, A., Dowsett, M., Goldhirsch, A., Untch, M., Mariani, G., Baselga, J., Kaufmann, M., Cameron, D., Bell, R., Bergh, J., Coleman, R., Wardley, A., Harbeck, N., Lopez, R. I., Mallmann, P., Gelmon, K., Wilcken, N., Wist, E., Rovira, P. S., Piccart-Gebhart, M., HERA Study Team, [Group Author] (2007) 2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial. LANCET, 369 (9555). pp. 29-36. ISSN 0140-6736

Arriola, E., Hui, E., Dowsett, M., Smith, I. E. (2007) Aromatase inhibitors and male breast cancer. CLINICAL AND TRANSLATIONAL ONCOLOGY, 9 (3). pp. 192-194. ISSN 1699-048X

Kote-Jarai, Z., Powles, T. J., Mitchell, G., Tidy, A., Ashley, S., Easton, D., Assersohn, L., Sodha, N., Salter, J., Gusterson, B., Dowsett, M., Eeles, R. (2007) BRCA1/BRCA2 mutation status and analysis of cancer family history in participants of the Royal Marsden Hospital tamoxifen chemoprevention trial. CANCER LETTERS, 247 (2). pp. 259-265. ISSN 0304-3835

Mouridsen, H., Keshaviah, A., Coates, A. S., Rabaglio, M., Castiglione-Gertsch, M., Sun, Z., Thurlimann, B., Mauriac, L., Forbes, J. F., Paridaens, R., Gelber, R. D., Colleoni, M., Smith, I., Price, K. N., Goldhirsch, A. (2007) Cardiovascular adverse events during adjuvant endocrine therapy for early breast cancer using letrozole or tamoxifen: Safety analysis of BIG 1-98 trial. JOURNAL OF CLINICAL ONCOLOGY, 25 (36). pp. 5715-5722. ISSN 0732-183X

Yap, Y. S., Kendall, A., Walsh, G., Banerji, U., Johnston, S. R. D., Smith, I. E., O'Brien, M. (2007) Clinical efficacy of capecitabine as first-line chemotherapy in metastatic breast cancer - How low can you go? BREAST, 16 (4). pp. 420-424. ISSN 0960-9776

Johnston, S. R. D., Martin, L. A., Leary, A., Head, J., Dowsett, M. (2007) Clinical strategies for rationale combinations of aromatase inhibitors with novel therapies for breast cancer. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 106 (1–5). pp. 180-186. ISSN 0960-0760

Leary, A. F., Sirohi, B., Johnston, S. R. (2007) Clinical trials update: endocrine and biological therapy combinations in the treatment of breast cancer. BREAST CANCER RESEARCH, 9 (5). ISSN 1465-5411

Arnedos, M., Seidman, A. D. (2007) Emerging targeted therapies for breast cancer. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA, 21 (2). pp. 321-340. ISSN 0889-8588

Johnston, S. R. D., Leary, A., Martin, L. A., Smith, I. E., Dowsett, M. (2007) Enhancing endocrine response with novel targeted therapies - Why have the clinical trials to date failed to deliver on the preclinical promise? CANCER, 112 (3 Supplement S). pp. 710-717. ISSN 0008-543X

Smith, I. E., Arnedos, M. (2007) The evolution of adjuvant endocrine therapy: Developments since St Gallen 2005. BREAST, 16 (Supplement 2). S4-S9. ISSN 0960-9776

Banerji, U., Kuciejewska, A., Ashley, S., Walsh, G., O'Brien, M., Johnston, S., Smith, I. (2007) Factors determining outcome after third line chemotherapy for metastatic breast cancer. BREAST, 16 (4). pp. 359-366. ISSN 0960-9776

Martin, L. A., Head, J. E., Pancholi, S., Salter, J., Quinn, E., Detre, S., Kaye, S., Howes, A., Dowsett, M., Johnston, S. R. D. (2007) The farnesyltransferase inhibitor R115777 (tipifarnib) in combination with tamoxifen acts synergistically to inhibit MCF-7 breast cancer cell proliferation and cell cycle progression in vitro and in vivo. MOLECULAR CANCER THERAPEUTICS, 6 (9). pp. 2458-2467. ISSN 1535-7163

Coates, A. S., Keshaviah, A., Thurlimann, B., Mouridsen, H., Mauriac, L., Forbes, J. F., Paridaens, R., Castiglione-Gertsch, M., Gelber, R. D., Colleoni, M., Lang, I., Del Mastro, L., Smith, I., Chirgwin, J., Nogaret, J. M., Pienkowski, T., Wardley, A., Jakobsen, E. H., Price, K. N., Goldhirsch, A. (2007) Five years of letrozole compared with tamoxifen as initial adjuvant therapy for postmenopausal women with endocrine-responsive early breast cancer: Update of study BIG 1-98. JOURNAL OF CLINICAL ONCOLOGY, 25 (5). pp. 486-492. ISSN 0732-183X

Benson, J. R., della Rovere, G. Q., Axilla Management Consensus Group, [Group Author] (2007) Management of the axilla in women with breast cancer. BREAST, 16 (2). pp. 130-136. ISSN 0960-9776

Pierga, J. Y., Reis-Filho, J. S., Cleator, S. J., Dexter, T., MacKay, A., Simpson, P., Fenwick, K., Iravani, M., Salter, J., Hills, M., Jones, C., Ashworth, A., Smith, I. E., Powles, T., Dowsett, M. (2007) Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapy. BRITISH JOURNAL OF CANCER, 96 (2). pp. 341-351. ISSN 0007-0920

Smith, I. E., Walsh, G., Skene, A., Llombart, A., Mayordomo, J. I., Detre, S., Salter, J., Clark, E., Magill, P., Dowsett, M. (2007) A phase II placebo-controlled trial of neoadjuvant anastrozole alone or with gefitinib in early breast cancer. JOURNAL OF CLINICAL ONCOLOGY, 25 (25). pp. 3816-3822. ISSN 0732-183X

Mauriac, L., Keshaviah, A., Debled, M., Mouridsen, H., Forbes, J. F., Thurlimann, B., Paridaens, R., Monnier, A., Lang, I., Wardley, A., Nogaret, J. M., Gelber, R. D., Castiglione-Gertsch, M., Price, K. N., Coates, A. S., Smith, I., Viale, G., Rabaglio, M., Zabaznyi, N., Goldhirsch, A. (2007) Predictors of early relapse in postmenopausal women with hormone receptor-positive breast cancer in the BIG 1-98 trial. ANNALS OF ONCOLOGY, 18 (5). pp. 859-867. ISSN 0923-7534

Anderson, H., Bulun, S., Smith, I., Dowsett, M. (2007) Predictors of response to aromatase inhibitors. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 106 (1–5). pp. 49-54. ISSN 0960-0760

Dowsett, M., Smith, I.E., Ebbs, S.R., Dixon, J.M., Skene, A., A'Hern, R., Salter, J., Detre, S., Hills, M., Walsh, G., IMPACT Trialists Group, [Group Author] (2007) Prognostic value of ki67 expression after short-term presurgical endocrine therapy for primary breast cancer. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 99 (2). pp. 167-170. ISSN 0027-8874

Dowsett, M., Salter, J., Hills, M., Detre, S., A'Hern, R., Smith, I. E. (2007) Short-term presurgical treatment for all? BREAST CANCER RESEARCH, 9 (Supplement 2). ISSN 1465-5411

Arriola, E., Rodriguez-Pinilla, S. M., Lambros, M. B. K., Jones, R. L., James, M., Savage, K., Smith, I. E., Dowsett, M., Reis-Filho, J. S. (2007) Topoisomerase II alpha amplification may predict benefit from adjuvant anthracyclines in HER2 positive early breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 106 (2). pp. 181-189. ISSN 0167-6806

Powles, T. J., Ashley, S., Tidy, A., Dowsett, M., Smith, I. A. (2007) Twenty-year follow-up of the royal Marsden randomized, double-blinded tamoxifen breast cancer prevention trial. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 99 (4). pp. 283-290. ISSN 0027-8874

Shanley, S., McReynolds, K., Ardern-Jones, A., Ahern, R., Fernando, I., Yarnold, J., Evans, G., Eccles, D., Hodgson, S., Ashley, S., Ashcroft, L., Tutt, A., Bancroft, E., Short, S., Smith, I., Gui, G., Barr, L., Baildam, A., Howell, A., Royle, G., Pierce, L., Easton, D., Eeles, R. (2006) Acute chemotherapy-related toxicity is not increased in BRCA1 and BRCA2 mutation carriers treated for breast cancer in the United Kingdom. CLINICAL CANCER RESEARCH, 12 (23). pp. 7033-7038. ISSN 1078-0432

Smith, I. E., Dowsett, M., Yap, Y. S., Walsh, G., Lonning, P. E., Santen, R. J., Hayes, D. (2006) Adjuvant aromatase inhibitors for early breast cancer after chemotherapy-induced arnenorrhoea: Caution and suggested guidelines. JOURNAL OF CLINICAL ONCOLOGY, 24 (16). pp. 2444-2447. ISSN 0732-183X

della Rovere, G. Q., Bonomi, R., Ashley, S., Benson, J. R. (2006) Axillary staging in women with small invasive breast tumours. EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 32 (7). pp. 733-737. ISSN 0748-7983

Banerjee, S., Reis-Filho, J. S., Ashley, S., Steele, D., Ashworth, A., Lakhani, S. R., Smith, I. E. (2006) Basal-like breast carcinomas: clinical outcome and response to chemotherapy. JOURNAL OF CLINICAL PATHOLOGY, 59 (7). pp. 729-735. ISSN 0021-9746

Johnston, S. R. D. (2006) Clinical efforts to combine endocrine agents with targeted therapies against epidermal growth factor receptor/human epidermal growth factor receptor 2 and mammalian target of rapamycin in breast cancer. CLINICAL CANCER RESEARCH, 12 (3). 1061S-1068S. ISSN 1078-0432

Gui, G. P. H., Kadayaprath, G., Darhouse, N., Self, J., Ward, A., A'Hern, R., Eeles, R. (2006) Clinical outcome and service implications of screening women at increased breast cancer risk from a family history. EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 32 (7). pp. 719-724. ISSN 0748-7983

Karnon, J., Delea, T., Johnston, S. R. D., Smith, R. (2006) Cost effectiveness of extended adjuvant letrozole in postmenopausal women after adjuvant tamoxifen therapy - The UK perspective. PHARMACOECONOMICS, 24 (3). pp. 237-250. ISSN 1170-7690

Delea, T. E., Karnon, J., Smith, R. E., Johnston, S. R. D., Brandman, J., Sung, J. C. Y., Goss, P. E. (2006) Cost-effectiveness of extended adjuvant letrozole therapy after 5 years of adjuvant tamoxifen therapy in postmenopausal women with early-stage breast cancer. AMERICAN JOURNAL OF MANAGED CARE, 12 (7). pp. 374-386. ISSN 1088-0224

della Rovere, G. Q., Benson, J. R. (2006) A critique of the sentinel node concept. BREAST, 15 (6). pp. 693-697. ISSN 0960-9776

Reis-Filho, J. S., Steele, D., Di Palma, S., Jones, R. L., Savage, K., James, M., Milanezi, F., Schmitt, F. C., Ashworth, A. (2006) Distribution and significance of nerve growth factor receptor (NGFR/p75(NTR)) in normal, benign and malignant breast tissue. MODERN PATHOLOGY, 19 (2). pp. 307-319. ISSN 0893-3952

Cleator, S. J., Powles, T. J., Dexter, T., Fulford, L., Mackay, A., Smith, I. E., Valgeirsson, H., Ashworth, A., Dowsett, M. (2006) The effect of the stromal component of breast tumours on prediction of clinical outcome using gene expression microarray analysis. BREAST CANCER RESEARCH, 8 (3). ISSN 1465-5411

Smith, I. E. (2006) The Extended Adjuvant Treatment Strategy in Early Breast Cancer: A New Standard of Care? AMERICAN JOURNAL OF CANCER, 5 (1). pp. 1-5. ISSN 1175-6357

Smith, I. (2006) Goals of treatment for patients with metastatic breast cancer. SEMINARS IN ONCOLOGY, 33 (1). S2-S5. ISSN 0093-7754

Yau, T., Swanton, C., Chua, S., Sue, A., Walsh, G., Rostom, A., Johnston, S. R., O'Brien, M. E. R., Smith, I. E. (2006) Incidence, pattern and timing of brain metastases among patients with advanced breast cancer treated with trastuzumab. ACTA ONCOLOGICA, 45 (2). pp. 196-201. ISSN 0284-186X

Kote-Jarai, Z., Salmon, A., Mengitsu, T., Copeland, M., Ardern-Jones, A., Locke, I., Shanley, S., Summersgill, B., Lu, Y. J., Shipley, J., Eeles, R. (2006) Increased level of chromosomal damage after irradiation of lymphocytes from BRCA1 mutation carriers. BRITISH JOURNAL OF CANCER, 94 (2). pp. 308-310. ISSN 0007-0920

Behranwala, K. A., Dua, R. S., Ross, G. M., Ward, A., A'Hern, R., Gui, G. P. H. (2006) The influence of radiotherapy on capsule formation and aesthetic outcome after immediate breast reconstruction using biodimensional anatomical expander implants. JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, 59 (10). pp. 1043-1051. ISSN 1748-6815

Johnston, S. R. D., Leary, A. (2006) Lapatinib: A novel EGFR/HER2 tyrosine kinase inhibitor for cancer. DRUGS OF TODAY, 42 (7). pp. 441-453. ISSN 0025-7656

Shanley, S., McReynolds, K., Ardern-Jones, A., Ahern, R., Fernando, I., Yarnold, J., Evans, G., Eccles, D., Hodgson, S., Ashley, S., Ashcroft, L., Tutt, A., Bancroft, E., Short, S., Gui, G., Barr, L., Baildam, A., Howell, A., Royle, G., Pierce, L., Easton, D., Eeles, R. (2006) Late toxicity is not increased in BRCA1/BRCA2 mutation carriers undergoing breast radiotherapy in the United Kingdom. CLINICAL CANCER RESEARCH, 12 (23). pp. 7025-7032. ISSN 1078-0432

Jones, R. L., Smith, I. E. (2006) Neoadjuvant treatment for early-stage breast cancer: opportunities to assess tumour response. LANCET ONCOLOGY, 7 (10). pp. 869-874. ISSN 1470-2045

Jones, R. L., Lakhani, S. R., Ring, A. E., Ashley, S., Walsh, G., Smith, I. E. (2006) Pathological complete response and residual DCIS following neoadjuvant chemotherapy for breast carcinoma. BRITISH JOURNAL OF CANCER, 94 (3). pp. 358-362. ISSN 0007-0920

Ford, H. E. R., Yap, Y. S., Miles, D. W., Makris, A., Hall, M., Miller, L., Harries, M., Smith, I. E., Johnston, S. R. D. (2006) A phase II study of weekly docetaxel in patients with anthracycline pretreated metastatic breast cancer. CANCER CHEMOTHERAPY AND PHARMACOLOGY, 58 (6). pp. 809-815. ISSN 0344-5704

Padhani, A. R., Hayes, C., Assersohn, L., Powles, T., Makris, A., Suckling, J., Leach, M. O., Husband, J. E. (2006) Prediction of clinicopathologic response of breast cancer to primary chemotherapy at contrast-enhanced MR imaging: Initial clinical results. RADIOLOGY, 239 (2). pp. 361-374. ISSN 0033-8419

Dowsett, M., Smith, I. E., Ebbs, S. R., Dixon, J. M., Skene, A., Griffith, C., Boeddinghaus, I., Salter, J., Detre, S., Hills, M., Ashley, S., Francis, S., Walsh, G., A'Hern, R. (2006) Proliferation and apoptosis as markers of benefit in neoadjuvant endocrine therapy of breast cancer. CLINICAL CANCER RESEARCH, 12 (3). 1024S-1030S. ISSN 1078-0432

della Rovere, G. Q., Trott, P., Filshie, J., Ashley, S., Hassanally, D. (2006) A prospective randomised study to evaluate the effectiveness of standard 23 gauge fine needle, compared with a thinner 27 gauge needle for breast cytology. BREAST, 15 (4). pp. 567-569. ISSN 0960-9776

Powles, T., Paterson, A., McCloskey, E., Schein, P., Scheffler, B., Tidy, A., Ashley, S., Smith, I., Ottestad, L., Kanis, J. (2006) Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026]. BREAST CANCER RESEARCH, 8 (3). ISSN 1465-5411

Nava, M. B., Cortinovis, U., Ottolenghi, J., Riggio, E., Permati, A., Catanuto, G., Greco, M., della Rovere, G. Q. (2006) Skin-reducing mastectomy. PLASTIC AND RECONSTRUCTIVE SURGERY, 118 (3). pp. 603-610. ISSN 0032-1052

Kouskos, E., Gui, G. P. H., Mantas, D., Revenas, K., Rallis, N., Antonopoulou, Z., Lampadariou, E., Gogas, H., Markopoulos, C. (2006) Wire localisation biopsy of non-palpable breast lesions: reasons for unsuccessful excision. EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, 27 (3). pp. 262-266. ISSN 0392-2936

Smith, I. (2005) Adjuvant treatment for early breast cancer. ANNALS OF ONCOLOGY, 16 (Supplement 2). pp. 182-187. ISSN 0923-7534

Martin, L. A., Pancholi, S., Chan, C. M. W., Farmer, I., Kimberley, C., Dowsett, M., Johnston, S. R. D. (2005) The anti-oestrogen ICI 182,780, but not tamoxifen, inhibits the growth of MCF-7 breast cancer cells refractory to long-term oestrogen deprivation through down-regulation of oestrogen receptor and IGF signalling. ENDOCRINE-RELATED CANCER, 12 (4). pp. 1017-1036. ISSN 1351-0088

Johnston SRD, Martin LA, Head J, Smith I, Dowsett M (2005) Aromatase inhibitors: Combinations with fulvestrant or signal transduction inhibitors as a strategy to overcome endocrine resistance. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 95 (1-5). pp. 173-181. ISSN 0960-0760

Dowsett M, Ebbs SR, Dixon JM, Skene A, Griffith C, Boeddinghaus I, Salter J, Detre S, Hills M, Ashley S, Francis S, Walsh G, Smith IE (2005) Biomarker changes during neoadjuvant anastrozole, tamoxifen, or the combination: Influence of hormonal status and HER-2 in breast cancer - A study from the IMPACT trialists. JOURNAL OF CLINICAL ONCOLOGY, 23 (11). pp. 2477-2492. ISSN 0732-183X

Erkkola R, Mattila L, Powles T, Heikkinen J, Toivola B, Korhonen P, Mustonen M (2005) Bone mineral density and lipid changes during 5 years of follow-up in a study of prevention of breast cancer with toremifene in healthy, high-risk pre- and post-menopausal women. BREAST CANCER RESEARCH AND TREATMENT, 93 (3). pp. 277-287. ISSN 0167-6806

Ring AE, Smith IE, Jones A, Shannon C, Galani E, Ellis PA (2005) Chemotherapy for breast cancer during pregnancy: An 18-year experience from five London teaching hospitals. JOURNAL OF CLINICAL ONCOLOGY, 23 (18). pp. 4192-4197. ISSN 0732-183X

Johnston, S. R. D. (2005) Clinical trials of intracellular signal transductions inhibitors for breast cancer - a strategy to overcome endocrine resistance. ENDOCRINE-RELATED CANCER, 12 (Supplement 1). S145-S157. ISSN 1351-0088

Johnston, S. R. D. (2005) Combinations of endocrine and biological agents: Present status of therapeutic and presurgical investigations. CLINICAL CANCER RESEARCH, 11 (2). 889S-899S. ISSN 1078-0432

Banerjee, S., Smith, I. E., Folkerd, L., Iqbal, J., Barker, P., Dowsett, M. (2005) Comparative effects of anastrozole, tamoxifen alone and in combination on plasma lipids and bone-derived resorption during neoadjuvant therapy in the impact trial. ANNALS OF ONCOLOGY, 16 (10). pp. 1632-1638. ISSN 0923-7534

Thurlimann, B., Keshaviah, A., Coates, A. S., Mouridsen, H., Mauriac, L., Forbes, J. F., Paridaens, R., Castiglione-Gertsch, M., Gelber, R. D., Rabaglio, M., Smith, I., Wardly, A., Price, K. N., Goldhirsch, A., [BIG 1-98 Collaborative Grp] (2005) A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer. NEW ENGLAND JOURNAL OF MEDICINE, 353 (26). pp. 2747-2757. ISSN 0028-4793

Gui GPH, Joubert DJ, Reichert R, Ward A, Lakhani S, Osin P, Nerurkar A, A'Hern R, Benson K, Underwood SR (2005) Continued axillary sampling is unnecessary and provides no further information to sentinel node biopsy in staging breast cancer. EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 31 (7). pp. 707-714. ISSN 0748-7983

Ring, A. E., Zabaglo, L., Ormerod, M. G., Smith, I. E., Dowsett, M. (2005) Detection of circulating epithelial cells in the blood of patients with breast cancer: comparison of three techniques. BRITISH JOURNAL OF CANCER, 92 (5). pp. 906-912. ISSN 0007-0920

Early Breast Cancer Trialists' Collaborative Group (includes Bliss J, Hall E, Smith I, Yarnold J, Powles TJ, A'Hern R) (2005) Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. LANCET, 365 (9472). pp. 1687-1717. ISSN 0140-6736

Martin, L. A., Farmer, I., Johnston, S. R. D., Ali, S., Dowsett, M. (2005) Elevated ERK1/ERK2/estrogen receptor cross-talk enhances estrogen-mediated signaling during long-term estrogen deprivation. ENDOCRINE-RELATED CANCER, 12 (Supplement 1). S75-S84. ISSN 1351-0088

Nicholson RI, Johnston SR (2005) Endocrine therapy - current benefits and limitations. BREAST CANCER RESEARCH AND TREATMENT, 93 (Supplement 1). S3-S10. ISSN 0167-6806

Dua RS, Gui GPH, Isacke CM (2005) Endothelial adhesion molecules in breast cancer invasion into the vascular and lymphatic systems. EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 31 (8). pp. 824-832. ISSN 0748-7983

Gui GPH, Kadayaprath G, Tan SM, Faliakou EC, Choy C, A'Hern R, Ward A (2005) Evaluation of outcome after immediate breast reconstruction: Prospective comparison of four methods. PLASTIC AND RECONSTRUCTIVE SURGERY, 115 (7). pp. 1916-1926. ISSN 0032-1052

Cleator, S. J., Makris, A., Ashley, S. E., Lal, R., Powles, T. J. (2005) Good clinical response of breast cancers to neoa uvant chemoendocrine therapy is associated with improved overall survival. ANNALS OF ONCOLOGY, 16 (2). pp. 267-272. ISSN 0923-7534

Dowsett, M., Johnston, S., Martin, L. A., Salter, J., Hills, M., Detre, S., Gutierrez, M. C., Mohsin, S. K., Shout, J., Allred, D. C., Osborne, C. K., Smith, I. (2005) Growth factor signalling and response to endocrine therapy: the Royal Marsden Experience. ENDOCRINE-RELATED CANCER, 12 (Supplement 1). S113-S117. ISSN 1351-0088

Johnston SR, Martin LA, Dowsett M (2005) Life following aromatase inhibitors - where now for endocrine sequencing?. BREAST CANCER RESEARCH AND TREATMENT, 93 (Supplement 1). S19-S25. ISSN 0167-6806

Wheatley, D., Adwani, A., Ebbs, S., Hanson, J., Ross, G., Sharma, A. K., Wells, P., Yarnold, J. (2005) Matching supraclavicular fields to the extent of axillary surgery in women prescribed radiotherapy for early stage carcinoma of the breast. CLINICAL ONCOLOGY, 17 (1). pp. 32-38. ISSN 0936-6555

Dowsett M, Martin LA, Smith I, Johnston S (2005) Mechanisms of resistance to aromatase inhibitors. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 95 (1-5). pp. 167-172. ISSN 0960-0760

Urruticoechea, A., Archer, C. D., Assersohn, L. A,. Gregory, R. K., Verrill, M., Mendes, R., Walsh, G., Smith, I. E., Johnston, S. R. D. (2005) Mitomycin C, vinblastine and cisplatin (MVP): an active and well-tolerated salvage regimen for advanced breast cancer. BRITISH JOURNAL OF CANCER, 92 (3). pp. 475-479. ISSN 0007-0920

Gutierrez MC, Detre S, Johnston S, Mohsin SK, Shou JN, Allred DC, Schiff R, Osborne CK, Dowsett M (2005) Molecular changes in tamoxifen-resistant breast cancer: Relationship between estrogen receptor, HER-2, and p38 mitogen-activated protein kinase. JOURNAL OF CLINICAL ONCOLOGY, 23 (11). pp. 2469-2476. ISSN 0732-183X

Johnston SRD (2005) Molecular insights into endocrine resistance. EJC SUPPLEMENTS, 3 (3). pp. 225-236. ISSN 1359-6349

Smith IE, Dowsett M, Ebbs SR, Dixon JM, Skene A, Blohmer JU, Ashley SE, Francis S, Boeddinghaus I, Walsh G (2005) Neoadjuvant treatment of postmenopausal breast cancer with anastrozole, tamoxifen, or both in combination: The Immediate Preoperative Anastrozole, Tamoxifen, or Combined with Tamoxifen (IMPACT) multicenter double-blind randomized trial. JOURNAL OF CLINICAL ONCOLOGY, 23 (22). pp. 5108-5116. ISSN 0732-183X

Chua, S., Smith, I. E., A'Hern, R. P., Coombes, G. A., Hickish, T. F., Robinson, A. C., Laing, R. W., O'Brien, M. E. R., Ebbs, S. R., Hong, A., Wardley, A., Mughal, T., Verrill, M., Dubois, D., Bliss, J. M. (2005) Neoadjuvant vinorelbine/epirubicin (VE) versus standard adriamycin/cyclophosphamide (AC) in operable breast cancer: analysis of response and tolerability in a randomised phase III trial (TOPIC 2). ANNALS OF ONCOLOGY, 16 (9). pp. 1435-1441. ISSN 0923-7534

Chan S, Scheulen ME, Johnston S, Mross K, Cardoso F, Dittrich C, Eiermann W, Hess D, Morant R, Semiglazov V, Borner M, Salzberg M, Ostapenko V, Illiger HJ, Behringer D, Bardy-Bouxin N, Boni J, Kong S, Cincotta M, Moore L (2005) Phase II study of temsirolimus (CCI-779), a novel inhibitor of mTOR, in heavily pretreated patients with locally advanced or metastatic breast cancer. JOURNAL OF CLINICAL ONCOLOGY, 23 (23). pp. 5314-5322. ISSN 0732-183X

Chen B, Gajdos C, Dardes R, Kidwai N, Johnston SRD, Dowsett M, Jordan VC (2005) Potential of endogenous estrogen receptor beta to influence the selective ER modulator ER beta complex. INTERNATIONAL JOURNAL OF ONCOLOGY, 27 (2). pp. 327-335. ISSN 1019-6439

Howell A, Cuzick J, Baum M, Buzdar A, Dowsett M, Forbes JF, Hoctin-Boes G, Houghton I, Locker GY, Tobias JS, ATAC Trialists' Group (2005) Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer. LANCET, 365 (9453). pp. 60-62. ISSN 0140-6736

Dowsett, M., Smith, I. E., Ebbs, S. R., Dixon, J. M., Skene, A., Griffith, C., Boeddinghaus, I., Salter, J., Detre, S., Hills, M., Ashley, S., Francis, S., Walsh, G. on behalf of the IMPACT Trialists (2005) Short-term changes in Ki-67 during neoadjuvant treatment of primary breast cancer with anastrozole or tamoxifen alone or combined correlate with recurrence-free survival. CLINICAL CANCER RESEARCH, 11 (2). 951S-958S. ISSN 1078-0432

Piccart-Gebhart, M. J., Procter, M., Leyland-Jones, B., Goldhirsch, A., Untch, M., Smith, I., Gianni, L., Baselga, J., Bell, R., Jackisch, C., Cameron, D., Dowsett, M., Barrios, C. H., Steger, G., Huang, C. S., Andersson, M., Inbar, M., Lichinitser, M., Lang, I., Nitz, U., Iwata, H., Thomssen, C., Lohrisch, C., Suter, T. M., Ruschoff, J., Suto, T., Greatorex, V., Ward, C., Straehle, C., McFadden, E., Dolci, M. S., Gelber, R. D. (2005) Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. NEW ENGLAND JOURNAL OF MEDICINE, 353 (16). pp. 1659-1672. ISSN 0028-4793

Smith IE (2004) Aromatase inhibitors - extending the benefits of adjuvant therapy beyond tamoxifen. BREAST, 13 (Supplement 1). S3-S9. ISSN 0960-9776

Johnston SRD, Gumbrell LA, Evans TRJ, Coleman RE, Smith IE, Twelves CJ, Soukop M, Rea DW, Earl HM, Howell A, Jones A, Canney P, Powles TJ, Haynes BP, Nutley B, Grimshaw R, Jarman M, Halbert GW, Brampton M, Haviland J, Dowsett M, Coombes RC (2004) A Cancer Research (UK) randomized phase II study of idoxifene in patients with locally advanced/metastatic breast cancer resistant to tamoxifen. CANCER CHEMOTHERAPY AND PHARMACOLOGY, 53 (4). pp. 341-348. ISSN 0344-5704

Jones RL, Berry GJ, Rubens RD, Miles DW (2004) Clinical and pathological absence of cardiotoxicity after liposomal doxorubicin. LANCET ONCOLOGY, 5 (9). pp. 575-577. ISSN 1470-2045

Behranwala KA, Nasiri N, A'Hern R, Gui GPH (2004) Clinical presentation and long-term outcome of pure myoepithelial carcinoma of the breast. EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 30 (4). pp. 357-361. ISSN 0748-7983

Clarke CL, Sandle J, Parry SC, Reis-Filho JS, O'Hare MJ, Lakhani SR (2004) Cytokeratin 5/6 in normal human breast: lack of evidence for a stem cell phenotype. JOURNAL OF PATHOLOGY, 204 (2). pp. 147-152. ISSN 0022-3417

Jones, C., Mackay, A., Grigoriadis, A., Cossu, A., Reis-Filho, J. S., Fulford, L., Dexter, T., Davies, S., Bulmer, K., Ford, E., Parry, S., Budroni, M., Palmieri, G., Neville, A. M., O'Hare, M. J., Lakhani, S. R. (2004) Expression profiling of purified normal human luminal and myoepithelial breast cells: Identification of novel prognostic markers for breast cancer. CANCER RESEARCH, 64 (9). pp. 3037-3045. ISSN 0008-5472

Keskek M, Kothari M, Ardehali B, Betambeau N, Nasiri N, Gui GPH (2004) Factors predisposing to cavity margin positivity following conservation surgery for breast cancer. EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 30 (10). pp. 1058-1064. ISSN 0748-7983

Johnston, S. (2004) Fulvestrant and the sequential endocrine cascade for advanced breast cancer. BRITISH JOURNAL OF CANCER, 90 (Supplement 1). S15-S18. ISSN 0007-0920

Millis, R. R., Pinder, S. E., Ryder, K., Howitt, R., Lakhani, S. R. (2004) Grade of recurrent in situ and invasive carcinoma following treatment of pure ductal carcinoma in situ of the breast. BRITISH JOURNAL OF CANCER, 90 (8). pp. 1538-1542. ISSN 0007-0920

Parton M, Dowsett M, Ashley S, Hills M, Lowe F, Smith IE (2004) High incidence of HER-2 positivity in inflammatory breast cancer. BREAST, 13 (2). pp. 97-103. ISSN 0960-9776

Gui GPH, Behranwala KA, Abdullah N, Seet J, Osin P, Nerurkar A, Lakhani SR (2004) The inframammary fold: contents, clinical significance and implications for immediate breast reconstruction. BRITISH JOURNAL OF PLASTIC SURGERY, 57 (2). pp. 146-149. ISSN 0007-1226

Berry MG, Gui GPH, Wells CA, Carpenter R (2004) Integrin expression and survival in human breast cancer. EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 30 (5). pp. 484-489. ISSN 0748-7983

Snelling JD, Abdullah N, Brown G, King DM, Moskovic E, Gui GPH (2004) Measurement of tumour size in case selection for breast cancer therapy by clinical assessment and ultrasound. EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 30 (1). pp. 5-9. ISSN 0748-7983

Kouskos E, Della Rovere GQ, Ball S, Koh DM, Freeman A (2004) Metastatic intramammary lymph primary presenting sign of breast nodes as the cancer. BREAST, 13 (5). pp. 416-420. ISSN 0960-9776

Jones, C., Ford, E., Gillett, C., Ryder, K., Merrett, S., Reis-Filho, J. S., Fulford, L. G., Hanby, A., Lakhani, S. R. (2004) Molecular cytogenetic identification of subgroups of grade III invasive ductal breast carcinomas with different clinical outcomes. CLINICAL CANCER RESEARCH, 10 (18). pp. 5988-5997. ISSN 1078-0432

Smith, I. E., A'Hern, R. P., Coombes, G. A., Howell, A., Ebbs, S. R., Hickish, T. F., O'Brien, M. E. R., Mansi, J. L., Wilson, C. B., Robinson, A. C., Murray, P. A., Price, C. G. A., Perren, T. J., Laing, R. W., Bliss, J. M. on behalf of the TOPIC Trial Group (2004) A novel continuous infusional 5-fluorouracil-based chemotherapy regimen compared with conventional chemotherapy in the neo-adjuvant treatment of early breast cancer: 5 year results of the TOPIC trial. ANNALS OF ONCOLOGY, 15 (5). pp. 751-758. ISSN 0923-7534

Ring, A. E., Smith, I. E., Ashley, S., Fulford, L. G., Lakhani, S. R. (2004) Oestrogen receptor status, pathological complete response and prognosis in patients receiving neoadjuvant chemotherapy for early breast cancer. BRITISH JOURNAL OF CANCER, 91 (12). pp. 2012-2017. ISSN 0007-0920

Lakhani, S. R., Manek, S., Penault-Llorca, F., Flanagan, A., Arnout, L., Merrett, S., McGuffog, L., Steele, D., Devilee, P., Klijn, J. G. M., Meijers-Heijboer, H., Radice, P., Pilotti, S., Nevanlinna, H., Butzow, R., Sobol, H., Jacquemier, J., Lyonet, D. S., Neuhausen, S. L., Weber, B., Wagner, T., Winqvist, R., Bignon, Y. J., Monti, F., Schmitt, F., Lenoir, G., Seitz, S., Hamman, U., Pharoah, P., Lane, G., Ponder, B., Bishop, D. T., Easton, D. F. (2004) Pathology of ovarian cancers in BRCA1 and BRCA2 carriers. CLINICAL CANCER RESEARCH, 10 (7). pp. 2473-2481. ISSN 1078-0432

Marsden J, Bradburn J on behalf of the Consumers' Advisory Group for Clinical Trials* (CAG-CT) and the Lynda Jackson Macmillan Centre (2004) Patient and clinician collaboration in the design of a national randomized breast cancer trial. HEALTH EXPECTATIONS: AN INTERNATIONAL JOURNAL OF PUBLIC PARTICIPATION IN HEALTH CARE AND HEALTH POLICY., 7 (1). pp. 6-17. ISSN 1369-6513

Kadouri L, Kote-Jarai Z, Easton DF, Hubert A, Hamoudi R, Glaser B, Abeliovich D, Peretz T, Eeles RA (2004) Polyglutamine repeat length in the AIB1 gene modifies breast cancer susceptibility in BRCA1 carriers. INTERNATIONAL JOURNAL OF CANCER, 108 (3). pp. 399-403. ISSN 0020-7136

Smith IE (2004) Radiotherapy alone following a complete response to neoadjuvant chemotherapy in operable breast cancer. AMERICAN JOURNAL OF ONCOLOGY REVIEW, 3 (4). pp. 221-223. ISSN 1542-9520

O'Brien, M. E. R., Wigler, N., Inbar, M., Rosso, R., Grischke, E., Santoro, A., Catane, R., Kieback, D. G., Tomczak, P., Ackland, S. P., Orlandi, F., Mellars, L., Alland, L., Tendler, C. (2004) Reduced cardiotoxicity and comparable efficacy in a phase III trial of pegylated liposomal doxorubicin HCl (CAELYX (TM)/Doxil (R)) versus conventional doxorubicin for first-line treatment of metastatic breast cancer. ANNALS OF ONCOLOGY, 15 (3). pp. 440-449. ISSN 0923-7534

Johnston SRD (2003) BMS-214662 (Bristol-Myers Squibb). IDRUGS, 6 (1). pp. 72-78. ISSN 1369-7056

Maisey NR, Sacks N, Johnston SRD (2003) Catheter fracture: a rare complication of totally implantable venous devices. BREAST, 12 (4). pp. 287-289. ISSN 0960-9776

Zabaglo, L., Ormerod, M. G., Parton, M., Ring, A., Smith, I. E., Dowsett, M. (2003) Cell filtration-laser scanning cytometry for the characterisation of circulating breast cancer cells. CYTOMETRY, 55 (2). pp. 102-108. ISSN 0196-4763

Detre, S., Riddler, S., Salter, J., A'Hern, R., Dowsett, M., Johnston, S. R. D. (2003) Comparison of the selective estrogen receptor modulator arzoxifene (LY353381) with tamoxifen on tumor growth and biomarker expression in an MCF-7 human breast cancer xenograft model. CANCER RESEARCH, 63 (19). pp. 6516-6522. ISSN 0008-5472

Davies, G., Salter, J., Hills, M., Martin, L. A., Sacks, N., Dowsett, M. (2003) Correlation between cyclooxygenase-2 expression and angiogenesis in human breast cancer. CLINICAL CANCER RESEARCH, 9 (7). pp. 2651-2656. ISSN 1078-0432

Shannon C, Ashley S, Smith IE (2003) Does timing of adjuvant chemotherapy for early breast cancer influence survival? JOURNAL OF CLINICAL ONCOLOGY, 21 (20). pp. 3792-3797. ISSN 0732-183X

Archer, C. D., Parton, M., Smith, I. E., Ellis, P. A., Salter, J., Ashley, S., Gui, G., Sacks, N., Ebbs, S. R., Allum, W., Nasiri, N., Dowsett, M. (2003) Early changes in apoptosis and proliferation following primary chemotherapy for breast cancer. BRITISH JOURNAL OF CANCER, 89 (6). pp. 1035-1041. ISSN 0007-0920

Martin, L. A., Farmer, I., Johnston, S. R. D., Ali, S., Marshall, C., Dowsett, M. (2003) Enhanced estrogen receptor (ER) alpha, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation. JOURNAL OF BIOLOGICAL CHEMISTRY, 278 (33). pp. 30458-30468. ISSN 0021-9258

Atula S, Powles T, Paterson A, McCloskey E, Nevalainen J, Kanis J (2003) Extended safety profile of oral clodronate after long-term use in primary breast cancer patients. DRUG SAFETY, 26 (9). pp. 661-671. ISSN 0114-5916

Gui GPH, Tan SM, Faliakou EC, Choy C, A'Hern R, Ward A (2003) Immediate breast reconstruction using biodimensional anatomical permanent expander implants: a prospective analysis of outcome and patient satisfaction. PLASTIC AND RECONSTRUCTIVE SURGERY, 111 (1). pp. 139-140. ISSN 0032-1052

Ring A, Webb A, Ashley S, Allum WH, Ebbs S, Gui G, Sacks NP, Walsh G, Smith IE (2003) Is surgery necessary after complete clinical remission following neoadjuvant chemotherapy for early breast cancer? JOURNAL OF CLINICAL ONCOLOGY, 21 (24). pp. 4540-4545. ISSN 0732-183X

Smith IE (2003) Letrozole versus tamoxifen in the treatment of advanced breast cancer and as neoadjuvant therapy. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 86 (3-5). pp. 289-293. ISSN 0960-0760

Rose C, Vtoraya O, Pluzanska A, Davidson N, Gershanovich M, Thomas R, Johnston S, Caicedo JJ, Gervasio H, Manikhas G, Ben Ayed F, Burdette-Radoux S, Chaudri-Ross HA, Lang R (2003) An open randomised trial of second-line endocrine therapy in advanced breast cancer: comparison of the aromatase inhibitors letrozole and anastrozole. EUROPEAN JOURNAL OF CANCER, 39 (16). pp. 2318-2327. ISSN 0959-8049

Cuzick J, Powles T, Veronesi U, Forbes J, Edwards R, Ashley S, Boyle P (2003) Overview of the main outcomes in breast-cancer prevention trials. LANCET, 361 (9354). pp. 296-300. ISSN 0140-6736

Johnston SRD, Hickish T, Ellis P, Houston S, Kelland L, Dowsett M, Salter J, Michiels B, Perez-Ruixo JJ, Palmer P, Howes A (2003) Phase II study of the efficacy and tolerability of two dosing regimens of the farnesyl transferase inhibitor, R115777, in advanced breast cancer. JOURNAL OF CLINICAL ONCOLOGY, 21 (13). pp. 2492-2499. ISSN 0732-183X

Chau, I., Kelleher, M. T., Cunningham, D., Norman, A., Wotherspoon, A., Trott, P., Rhys-Evans, P. G., Querci-Della Rovere, Q., Brown, G., Allen, M., Waters, J. S., Haque, S., Murray, T., Bishop, L. (2003) Rapid access multidisciplinary lymph node diagnostic clinic: analysis of 550 patients. BRITISH JOURNAL OF CANCER, 88 (3). pp. 354-361. ISSN 0007-0920

Behranwala KA, Nasiri N, Abdullah N, Trott PA, Gui GPH (2003) Squamous cell carcinoma of the breast: clinico-pathologic implications and outcome. EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 29 (4). pp. 386-389. ISSN 0748-7983

Assersohn L, Salter J, Powles TJ, A'Hern R, Makris A, Gregory RK, Chang J, Dowsett M (2003) Studies of the potential utility of Ki67 as a predictive molecular marker of clinical response in primary breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 82 (2). pp. 113-123. ISSN 0167-6806

Karnon, J. R., Johnston, S. R. D., Jones, T., Glendenning, A. (2003) A trial-based cost-effectiveness analysis of letrozole followed by tamoxifen versus tamoxifen followed by letrozole for postmenopausal advanced breast cancer. ANNALS OF ONCOLOGY, 14 (11). pp. 1629-1633. ISSN 0923-7534

Cleator, S., Parton, M., Dowsett, M. (2002) The biology of neoadjuvant chemotherapy for breast cancer. ENDOCRINE-RELATED CANCER, 9 (3). pp. 183-195. ISSN 1351-0088

Behranwala KA, Gui GPH (2002) Breast cancer in the inframammary fold: is preserving the inframammary fold during mastectomy justified? BREAST, 11 (4). pp. 340-342. ISSN 0960-9776

Powles, T. J. (2002) Breast cancer prevention. ONCOLOGIST, 7 (1). pp. 60-64. ISSN 1083-7159

Parton, M., Krajewski, S., Smith, I., Krajewska, M., Archer, C., Naito, M., Ahern, R., Reed, J., Dowsett, M. (2002) Co-ordinate expression of apoptosis associated proteins in human breast cancer before and during chemotherapy. CLINICAL CANCER RESEARCH, 8 (7). pp. 2100-2108. ISSN 1078-0432

Smith, D. H., Adams, J. R., Johnston, S. R. D., Gordon, A., Drummond, M. F., Bennett, C. L. (2002) A comparative economic analysis of pegylated liposomal doxorubicin versus topotecan in ovarian cancer in the USA and the UK. ANNALS OF ONCOLOGY, 13 (10). pp. 1590-1597. ISSN 0923-7534

Di Leo A, Dowsett M, Horten B, Penault-Llorca F (2002) Current status of HER2 testing. ONCOLOGY, 63 (Supplement 1). pp. 25-32. ISSN 0030-2414

Seddon B, Cook A, Gothard L, Salmon E, Latus K, Underwood SR, Yarnold J (2002) Detection of defects in myocardial perfusion imaging in patients with early breast cancer treated with radiotherapy. RADIOTHERAPY AND ONCOLOGY, 64 (1). pp. 53-63. ISSN 0167-8140

Harries, M., Smith, I. (2002) The development and clinical use of trastuzumab (Herceptin). ENDOCRINE-RELATED CANCER, 9 (2). pp. 75-85. ISSN 1351-0088

Lewis JS, Gordon AB, Gui GPH (2002) The drainage of large seromas: A quick, closed system. PLASTIC AND RECONSTRUCTIVE SURGERY, 110 (6). pp. 1611-1612. ISSN 0032-1052

Bartram C, Brown G (2002) Endorectal ultrasound and magnetic resonance imaging in rectal cancer staging. GASTROENTEROLOGY CLINICS OF NORTH AMERICA, 31 (3). pp. 827-839. ISSN 0889-8553

Assersohn, L., Gangi, L., Zhao, Y. D., Dowsett, M., Simon, R., Powles, T. J., Liu, E. T. (2002) The feasibility of using fine needle aspiration from primary breast cancers for cDNA microarray analyses. CLINICAL CANCER RESEARCH, 8 (3). pp. 794-801. ISSN 1078-0432

Padhani AR, Yarnold JR, Regan J, Husband JE (2002) Magnetic resonance imaging of induration in the irradiated breast. RADIOTHERAPY AND ONCOLOGY, 64 (2). pp. 157-162. ISSN 0167-8140

Chan CMW, Martin LA, Johnston SRD, Ali S, Dowsett M (2002) Molecular changes associated with the acquisition of oestrogen hypersensitivity in MCF-7 breast cancer cells on long-term oestrogen deprivation. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 81 (4-5). pp. 333-341. ISSN 0960-0760

Shannon C, Walsh G, Sapunar F, A'Hern R, Smith I (2002) Occult primary breast carcinoma presenting as axillary lymphadenopathy. BREAST, 11 (5). pp. 414-418. ISSN 0960-9776

De Boer, R. H., Eisen, T. G., Ellis, P. A., Johnston, S. R. D., Walsh, G., Ashley, S., Smith, I. E. (2002) A randomised phase II study of conventional versus accelerated infusional chemotherapy with granulocyte colony-stimulating factor support in advanced breast cancer. ANNALS OF ONCOLOGY, 13 (6). pp. 889-894. ISSN 0923-7534

Powles T, Paterson S, Kanis JA, McCloskey E, Ashley S, Tidy A, Rosenqvist K, Smith I, Ottestad L, Legault S, Pajunen M, Nevantaus A, Mannisto E, Suovuori A, Atula S, Nevalainen J, Pylkkanen L (2002) Randomized, placebo-controlled trial of clodronate in patients with primary operable breast cancer. JOURNAL OF CLINICAL ONCOLOGY, 20 (15). pp. 3219-3224. ISSN 0732-183X

Tan SM, Behranwala KA, Trott PA, Nasiri NA, Moskovic E, Brown G, King DM, Sacks NPM, Gui GPH (2002) A retrospective study comparing the individual modalities of triple assessment in the pre-operative diagnosis of invasive lobular breast carcinoma. EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 28 (3). pp. 203-208. ISSN 0748-7983

Green, H., Ross, G., Peacock, J., Owen, R., Yarnold, J., Houlston, R. (2002) Variation in the manganese superoxide dismutase gene (SOD2) is not a major cause of radiotherapy complications in breast cancer patients. RADIOTHERAPY AND ONCOLOGY, 63 (2). pp. 213-216. ISSN 0167-8140

Tsopelas, C., Sutton, R. (2002) Why certain dyes are useful for localizing the sentinel lymph node. JOURNAL OF NUCLEAR MEDICINE, 43 (10). pp. 1377-1382. ISSN 0161-5505

Gui GPH (2001) Assessment of the patient with breast problems. TRENDS IN UROLOGY, GYNAECOLOGY AND SEXUAL HEALTH .

Powles T (2001) Breast cancer chemoprevention - Quo vadis? BREAST, 12 (6). pp. 379-386. ISSN 0960-9776

Cauley JA, Norton L, Lippman ME, Eckert S, Krueger KA, Purdie DW, Farrerons J, Karasik A, Mellstrom D, Ng KW, Stepan JJ, Powles TJ, Morrow M, Costa A, Silfen SL, Walls EL, Schmitt H, Muchmore DB, Jordan VC (2001) Continued breast cancer risk reduction in postmenopausal women treated with raloxifene: 4-year results from the MORE trial. BREAST CANCER RESEARCH AND TREATMENT, 65 (2). pp. 125-134. ISSN 0167-6806

Stone, J. G., Coleman, G., Gusterson, B., Marossy, A., Lakhani, S. R., Ward, A., Nash, A., McKinna, A., A'Hern, R., Stratton, M. R., Houlston, R. S. (2001) Contribution of germline MLH1 and MSH2 mutations to lobular carcinoma in situ of the breast. CANCER LETTERS, 167 (2). pp. 171-174. ISSN 0304-3835

Smith IE (2001) Efficacy and safety of Herceptin in women with metastatic breast cancer: results from pivotal clinical studies. ANTI-CANCER DRUGS, 12 (Supplement 4). S3-S10. ISSN 0959-4973

Johnston, S. R. D. (2001) Endocrine manipulation in advanced breast cancer: Recent advances with SERM therapies. CLINICAL CANCER RESEARCH, 7 (12). 4376S-4387S. ISSN 1078-0432

Johnston, S. R. D., Kelland, L. R. (2001) Farnesyl transferase inhibitors - a novel therapy for breast cancer. ENDOCRINE-RELATED CANCER, 8 (3). pp. 227-235. ISSN 1351-0088

Smith I (2001) Future directions in the adjuvant treatment of breast cancer: The role of trastuzumab. ANNALS OF ONCOLOGY, 12 (Supplement 1). S75-S79. ISSN 0923-7534

Gui GPH (2001) The future of ductal carcinoma in situ of the breast. WOMEN'S ONCOLOGY REVIEW .

Dowsett, M., Harper-Wynne, C., Boeddinghaus, I., Salter, J., Hills, M., Dixon, M., Ebbs, S., Gui, G., Sacks, N., Smith, I. (2001) HER-2 amplification impedes the antioproliferative effects of hormone therapy in oestrogen receptor-positive primary breast cancer. CANCER RESEARCH, 61 (23). pp. 8452-8458. ISSN 0008-5472

Gui GPH, Hogben RKF, Walsh G, A'Hern R, Eeles R (2001) The incidence of breast cancer from screening women according to predicted family history risk: does annual clinical examination add to mammography? EUROPEAN JOURNAL OF CANCER, 37 (13). pp. 1668-1673. ISSN 0959-8049

Gordon, A. B., Nasiri, N., Gui, G. P. H., Sacks, N. P. M. (2001) Nipple excised and areola retained after total mastectomy (NEAT). JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, 94 (4). pp. 185-186. ISSN 0141-0768

Lloyd, M. S., Nash, A. G. (2001) 'Occult' breast cancer. ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND, 83 (6). pp. 420-424. ISSN 0035-8843

Kapiris I, Nasiri N, A'Hern R, Healey V, Gui GPH (2001) Outcome and predictive factors of local recurrence and distant metastases following primary surgical treatment of high-grade malignant phyllodes tumours of the breast. EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 27 (8). pp. 723-730. ISSN 0748-7983

Miles DW, Smith IE, Coleman RE, Calvert AH, Lind MJ (2001) A phase II study of pemetrexed disodium (LY231514) in patients with locally recurrent or metastatic breast cancer. EUROPEAN JOURNAL OF CANCER, 37 (11). pp. 1366-1371. ISSN 0959-8049

Harden SP, Neal AJ, Al-Nasiri N, Ashley S, della Revere GQ (2001) Predicting axillary lymph node metastases in patients with T-1 infiltrating ductal carcinoma of the breast. BREAST, 10 (2). pp. 155-159. ISSN 0960-9776

Saunders Y, Stebbing J, Broadley K, Johnston SRD (2001) Recurrent locally advanced breast cancer: The treatment of chest wall disease with further chemotherapy. CLINICAL ONCOLOGY, 13 (3). pp. 195-199. ISSN 0936-6555

Ross PJ, Powles TJ (2001) Results and implications of the Royal Marsden and other tamoxifen chemoprevention trials. CLINICAL BREAST CANCER, 2 (1). pp. 33-40. ISSN 1526-8209

Leyland-Jones, B., Smith, I. (2001) Role of Herceptin in primary breast cancer: Views from North America and Europe. ONCOLOGY, 61 (Supplement 2). pp. 83-91. ISSN 0030-2414

Fersht N, Vini L, A'Hern R, Harmer C (2001) The role of radiotherapy in the management of elevated calcitonin after surgery for medullary thyroid cancer. THYROID, 11 (12). pp. 1161-1168. ISSN 1050-7256

Powles TJ (2001) The Royal Marsden Hospital (RMH) trial - Key points and remaining questions. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 949 . pp. 109-112. ISSN 0077-8923

Fallowfield LJ, Fleissig A, Edwards R, West A, Powles TJ, Howell A, Cuzick J (2001) Tamoxifen for the prevention of breast cancer: psychosocial impact on women participating in two randomised controlled trials. JOURNAL OF CLINICAL ONCOLOGY, 19 (7). pp. 1885-1892. ISSN 0732-183X

Whitehouse PA, Baber Y, Brown G, Moskovic E, King DM, Gui GPH (2001) The use of ultrasound by breast surgeons in outpatients: an accurate extension of clinical diagnosis. EUROPEAN JOURNAL OF SURGICAL ONCOLOGY, 27 (7). pp. 611-616. ISSN 0748-7983

Book Section

Gregory K, Smith I. (2003) Breast cancer. In: Cancer in Primary Care. Martin Dunitz, London, UK, pp. 97-106. ISBN 978-190186526-4

Baselga J, Johnston SRD. (2003) Future perspectives - Ras inhibitors. In: Breast Cancer Therapy Annual. Martin Dunitz, London, UK, pp. 183-193. ISBN 978-185317898-6

Judson I, Ross G. (2003) Mechanisms of cancer therapy. In: Cancer in Primary Care. Martin Dunitz, London, UK, pp. 81-88. ISBN 978-190186526-4

Johnston SRD. (2003) Predictors of response and resistance to medical therapy: chemotherapy. In: Medical Therapy of Breast Cancer. Cambridge University Press, Cambridge, UK, pp. 246-263. ISBN 978-052149632-2

Johnston SRD. (2001) Breast cancer - advances in hormonal therapy. In: Primary Care in the new NHS - Autumn 2001. Association of Primary Care Groups and Trusts., London, UK, pp. 193-198.

Johston SRD, Smith IE, Dowsett M (2001) Place of aromatase inhibitors in the endocrine therapy of breast cancer. In: Aromatase Inhibition and Breast Cancer. Informa Healthcare, New York, USA, pp. 29-49. ISBN 978-082470412-4

Correction

Powles, T., Paterson, A., McCloskey, E., Schein, P., Scheffler, B., Tidy, A., Ashley, S., Smith, I., Ottestad, L., Kanis, J. (2006) Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer [ISRCTN83688026] (vol 8, pg R13, 2006). [Correction]

Tan, S. M., Behranwala, K. A., Trott, P. A., Nasim, N. A., Moskovic, E., Brown, G., King, D. M., Sacks, N. P. M., Gui, G. P. H. (2002) A retrospective study comparing the individual modalities of triple assessment in the pre-operative diagnosis of invasive lobular breast carcinoma (vol 28, pg 203, 2002). [Correction]

Editorial

Powles, T. J. (2008) Addressing concerns about breast cancer prevention - The Vogel article reviewed. [Editorial]

Dodwell, D., Coombes, G., Bliss, J. M., Kilburn, L. S., Johnston, S., SoFEA Trial Management Grp, [Group Author] (2008) Combining fulvestrant (Faslodex (TM)) with continued oestrogen suppression in endocrine-sensitive advanced breast cancer: the SoFEA trial. [Editorial]

Leary, A., Smith, I. E. (2008) Survival from breast cancer in England and Wales up to 2001 - Clinical commentary. [Editorial]

Kilburn, L. S., T.N.T. Trial Management Group, [Group Author] (2008) 'Triple negative' breast cancer: a new area for phase III breast cancer clinical trials. [Editorial]

Smith, I. E., Chua, S. (2006) ABC of breast diseases - Medical treatment of early breast cancer. I: adjuvant treatment. [Editorial]

Smith, I. E., Chua, S. (2006) ABC of breast diseases - Medical treatment of early breast cancer. II: endocrine therapy. [Editorial]

Smith, I. E., Chua, S. (2006) ABC of breast diseases - Medical treatment of early breast cancer. IV: neoadjuvant treatment. [Editorial]

Powles, T. (2006) The Jordan article reviewed. [Editorial]

Smith, I., Chua, S. (2006) Medical treatment of early breast cancer. III: chemotherapy. [Editorial]

Come, S. E., Buzdar, A. U., Ingle, J. N., Arteaga, C. L., Brown, M., Dowsett, M., Hilsenbeck, S. G., Kumar, R., Johnston, S. R. D., Lee, A. V., Paik, S., Pritchard, K. I., Winer, E. P., Hart, C. (2006) Proceedings of the Fifth International Conference on Recent Advances and Future Directions in Endocrine Therapy for Breast Cancer: Conference summary statement. [Editorial]

Smith, I. E. (2006) Proceedings of the Satellite Symposium "ATurning Point in Adjuvant Therapy: Optimizing the Use of Aromatase Inhibitors" at the 5th European Breast Cancer Conference, Nice, France, 22 March 2006 - Introduction. [Editorial]

Smith, I. E. (2006) Trastuzumab for early breast cancer: Hope or hype? [Editorial]

Yarnold, J. (2005) Assessing breast cosmesis after radiotherapy: What do we want to measure? [Editorial]

Johnston, S. R. (2005) Fulvestrant (Faslodex (R)): extending the reach of endocrine therapy? [Editorial]

Ebbs S (2005) Smoking and breast cancer. [Editorial]

Smith IE, Ross GM (2004) Breast radiotherapy after lumpectomy - No longer always necessary. [Editorial]

Lakhani SR (2004) Putting the brakes on cylindromatosis? [Editorial]

Smith IE, Janicke F (2004) Recent advances in the treatment of breast cancer. [Editorial]

Smith IE (2003) Hormonal therapy: introduction. [Editorial]

Come, S. E., Buzdar, A. U., Arteaga, C. L., Brodie, A. M., Davidson, N. E., Dowsett, M., Ingle, J. N., Johnston, S. R. D., Lee, A. V., Osborne, C. K., Pritchard, K. I., Vogel, V. G., Winer, E. P., Hart, C. S. (2003) Second international conference on recent advances and future directions in endocrine manipulation of breast cancer: summary consensus statement. [Editorial]

Powles TJ (2002) Anti-oestrogenic prevention of breast cancer - the make or break point. [Editorial]

Dowsett, M., Howell, A. (2002) Breast cancer: Aromatase inhibitors take on tamoxifen. [Editorial]

Sarker SK, Faliakou EC, Gui GPH (2001) Surgical technique: submuscular placement of breast implant ports with delayed expansion following ultrasound localization. [Editorial]

Letter

Rainsbury, R. M., MacNeill, F. (2009) Surgery for breast cancer Oncoplastic surgery is promising. [Letter]

Lee, A. J. X., East, P., Pepper, S., Nicke, B., Szallasi, Z., Eklund, A. C., Downward, J., Swanton, C. (2008) Concordance of exon array and real-time PCR assessment of gene expression following cancer cell cytotoxic drug exposure. [Letter]

Bartlett, J. M. S., Ellis, I. O., Dowsett, M., Mallon, E. A., Cameron, D. A., Johnston, S., Hall, E., A'Hern, R., Peckitt, C., Bliss, J. M., Johnson, L., Barrett-Lee, P., Ellis, P. (2008) In early-stage breast cancer, the estrogen receptor interacts with correlation between human epidermal growth factor receptor 2 status and age at diagnosis, tumor grade, and lymph node involvement - In reply. [Letter]

Dowsett, M., Smith, I. E. (2007) Re: Prognostic value of Ki67 expression after short-term presurgical endocrine therapy for primary breast cancer - Response. [Letter]

Smith, I. E., Procter, M., Gelber, R., Piccart-Gebhart, M. (2007) Trastuzumab after adjuvant chemotherapy in older patients - Reply. [Letter]

Dowsett, M., Urruticoechea, A., Smith, I. E. (2006) Ki-67 correlates with in vivo bromodeoxyuridine labeling index in operable breast cancer - Reply. [Letter]

Gui, G. (2006) Meta-analysis of sentinel lymph node biopsy after preoperative chemotherapy in patients with breast cancer (Br J Surg 2006; 93: 539-546). [Letter]

Smith, I. E. [and on behalf of 18 other signatories including Bliss J] (2006) Trastuzumab for early breast cancer. [Letter]

Popat, S., Smith, I. E. (2005) Re: Neoadjuvant versus adjuvant systemic treatment in breast cancer: A meta-analysis. [Letter]

Bowling JCR, Powles A, Nasiri N, Searle A, Bunker CB (2005) Spontaneous regression of extramammary Paget's disease after excision of primary apocrine carcinoma, in an immunosuppressed patient. [Letter]

Nava M, Catanuto G, Querci della Rovere G (2005) Wise pattern mastectomy with immediate breast reconstruction by P. Prathap and R.N.L. Harland. The Breast 2004; 13 : 502-5. [Letter]

Davies, G. L. S., Sacks, N. P. M., Gordon, A. B., Trott, P. A. (2004) Erosive adenomatosis of the nipple - a report of three cases. [Letter]

Benson JR, della Rovere GQ (2003) Towards a scientific basis for oncoplastic breast surgery. [Letter]

Behranwala KA, Gui GPH (2002) The Koebner phenomenon in a myocutaneous flap following immediate breast reconstruction. [Letter]

della Rovere, G. Q., Warren, R. (2001) Detection of breast cancer - Mammography should be available. [Letter]

Benson JR, Querci della Rovere GQ, Nasiri N (2001) Eyelid metastasis. [Letter]

Querci della Rovere, G., Benson, J. R. (2001) Irinotecan-induced dysarthria. [Letter]

Querci della Rovere G, Benson JR, Childs P, Hastings L, Johri A (2001) Is the 'tangential' or 'parallel' approach to FNA cytology of breast lesions always possible and compatible with reliable sampling? [Letter]

Benson JR, della Rovere GQ (2001) Sentinel-node biopsy in breast cancer. [Letter]

Review Article

Parton, M., Smith, I. E. (2008) Controversies in the management of patients with breast cancer: Adjuvant endocrine therapy in premenopausal women. JOURNAL OF CLINICAL ONCOLOGY, 26 (5). pp. 745-752. ISSN 0732-183X

Swanton, C., Szallasi, Z., Brenton, J. D., Downward, J. (2008) Functional genomic analysis of drug sensitivity pathways to guide adjuvant strategies in breast cancer. BREAST CANCER RESEARCH, 10 (5). ISSN 1465-5411

Urruticoechea, A., Arnedos, M., Walsh, G., Dowsett, M., Smith, I. E. (2008) Ovarian protection with goserelin during adjuvant chemotherapy for pre-menopausal women with early breast cancer (EBC). BREAST CANCER RESEARCH AND TREATMENT, 110 (3). pp. 411-416. ISSN 0167-6806

Gralow, J. R., Burstein, H. J., Wood, W., Hortobagyi, G. N., Gianni, L., Von Minckwitz, G., Buzdar, A. U., Smith, I. E., Symmans, W. F., Singh, B., Winer, E. P. (2008) Preoperative therapy in invasive breast cancer: Pathologic assessment and systemic therapy issues in operable disease. JOURNAL OF CLINICAL ONCOLOGY, 26 (5). pp. 814-819. ISSN 0732-183X

Arnedos, M., Sutherland, S., Ashley, S., Smith, I. (2008) Routine prophylactic granulocyte colony stimulating factor (GCSF) is not necessary with accelerated (dose dense) paclitaxel for early breast cancer. BREAST CANCER RESEARCH AND TREATMENT, 112 (1). pp. 1-4. ISSN 0167-6806

O'Brien, M. E. R. (2008) Single-agent treatment with pegylated liposomal doxorubicin for metastatic breast cancer. ANTI-CANCER DRUGS, 19 (1). pp. 1-7. ISSN 0959-4973

Popat, S., Smith, I. E. (2008) Therapy insight: anthracyclines and trastuzumab - the optimal management of cardiotoxic side effects. NATURE CLINICAL PRACTICE ONCOLOGY, 5 (6). pp. 324-335. ISSN 1743-4254

Andreetta, C., Smith, I. (2007) Adjuvant endocrine therapy for early breast cancer. CANCER LETTERS, 251 (1). pp. 17-27. ISSN 0304-3835

Arnedos, M., Smith, I. (2007) Progression of endocrine therapies for breast cancer: where are we headed? EXPERT REVIEW OF ANTICANCER THERAPY, 7 (11). pp. 1651-1664. ISSN 1473-7140

Leary, A., Johnston, S. R. D. (2007) Small molecule signal transduction inhibitors for the treatment of solid tumors. CANCER INVESTIGATION, 25 (5). pp. 347-365. ISSN 0735-7907

Dua, R. S., Isacke, C. M., Gui, G. P. H. (2006) The intraductal approach to breast cancer biomarker discovery. JOURNAL OF CLINICAL ONCOLOGY, 24 (7). pp. 1209-1216. ISSN 0732-183X

Smith, I. E. (2006) Overview of gemcitabine activity in advanced breast cancer. SEMINARS IN ONCOLOGY, 33 (3). S19-S23. ISSN 0093-7754

Dodwell, D., Wardley, A., Johnston, S. (2006) Postmenopausal advanced breast cancer: Options for therapy after tamoxifen and aromatase inhibitors. BREAST, 15 (5). pp. 584-594. ISSN 0960-9776

Hall, J., Knee, G., A'Hern, R. P., Clarke, J., Glees, J. P., Ford, H. T., Eeles, R. A. (2006) Sweat-gland tumours: A clinical review of cases in one centre over 20 years. CLINICAL ONCOLOGY, 18 (4). pp. 351-359. ISSN 0936-6555

Ring, A. E., Smith, I. E., Ellis, P. A. (2005) Breast cancer and pregnancy. ANNALS OF ONCOLOGY, 16 (12). pp. 1855-1860. ISSN 0923-7534

Johnston, S. R. D. (2005) Endocrinology and hormone therapy in breast cancer - Selective oestrogen receptor modulators and downregulators for breast cancer - have they lost their way? BREAST CANCER RESEARCH, 7 (3). pp. 119-130. ISSN 1465-5411

Urruticoechea, A., Smith, I. E., Dowsett, M. (2005) Proliferation marker Ki-67 in early breast cancer. JOURNAL OF CLINICAL ONCOLOGY, 23 (28). pp. 7212-7220. ISSN 0732-183X

Smith IE (2004) Aromatase inhibitors in early breast cancer therapy. SEMINARS IN ONCOLOGY, 31 (6). pp. 9-14. ISSN 0093-7754

Gore M, Johnston SRD (2004) Biology of cancer: clinical applications. MEDICINE, 32 (3). pp. 6-11. ISSN 1357-3039

Violet, J. A., Harmer, C. (2004) Breast cancer: improving outcome following adjuvant radiotherapy. BRITISH JOURNAL OF RADIOLOGY, 77 (922). pp. 811-820. ISSN 0007-1285

Swanton C (2004) Cell-cycle targeted therapies. LANCET ONCOLOGY, 5 (1). pp. 27-36. ISSN 1470-2045

Ring A, Smith IE, Dowsett M (2004) Circulating tumour cells in breast cancer. LANCET ONCOLOGY, 5 (2). pp. 79-88. ISSN 1470-2045

Jones, Robin L., Smith, Ian E. (2004) Efficacy and safety of trastuzumab. EXPERT OPINION ON DRUG SAFETY, 3 (4). pp. 317-27. ISSN 1474-0338

Bell R, Verma S, Untch M, Cameron D, Smith I (2004) Maximizing clinical benefit with trastuzumab. SEMINARS IN ONCOLOGY, 31 (5). pp. 35-44. ISSN 0093-7754

Head, J., Johnston, S. R. D. (2004) New targets for therapy in breast cancer - Farnesyltransferase inhibitors. BREAST CANCER RESEARCH, 6 (6). pp. 262-268. ISSN 1465-5411

Johnston SRD (2004) Ovarian cancer: Review of the National Institute for Clinical Excellence (NICE) guidance recommendations. CANCER INVESTIGATION, 22 (5). pp. 730-742. ISSN 0735-7907

Behranwala KA, Tisdall M, Habib NH, Canelo R (2004) Spontaneous bilobar subcapsular hematoma of the liver while undergoing anticoagulation therapy: Our experience and review of the literature. INTERNATIONAL SURGERY, 89 (4). pp. 212-216. ISSN 0020-8868

Saunders Y, Ross JR, Broadley KE, Edmonds PM, Patel S, on behalf of Steering Group (includes Dearnaley D, Dowsett M, Ahern R, Powles T, Johnston S) (2004) Systematic review of bisphosphonates for hypercalcaemia of malignancy. PALLIATIVE MEDICINE, 18 (5). pp. 418-431. ISSN 0269-2163

Howell SJ, Johnston SRD, Howell A (2004) The use of selective estrogen receptor modulators and selective estrogen receptor down-regulators in breast cancer. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 18 (1). pp. 47-66. ISSN 1521-690X

Powles TJ (2003) Anti-oestrogenic chemoprevention of breast cancer - the need to progress. EUROPEAN JOURNAL OF CANCER, 39 (5). pp. 572-579. ISSN 0959-8049

Johnston SRD, Dowsett M (2003) Aromatase inhibitors for breast cancer: Lessons from the laboratory. NATURE REVIEWS CANCER, 3 (11). pp. 821-831. ISSN 1474-175X

Mauriac L, Smith I (2003) Aromatase inhibitors in early breast cancer treatment. SEMINARS IN ONCOLOGY, 30 (4 Supplement 14). pp. 46-57. ISSN 0093-7754

Shannon C, Smith IE (2003) Breast cancer in adolescents and young women. EUROPEAN JOURNAL OF CANCER, 39 (18). pp. 2632-2642. ISSN 0959-8049

Mouridsen HT, Rose C, Brodie AH, Smith IE (2003) Challenges in the endocrine management of breast cancer. BREAST, 12 (Supplement 2). s2-s19. ISSN 0960-9776

Bilous, M., Dowsett, M., Hanna, W., Isola, J., Lebeau, A., Moreno, A., Penault-Llorca, F., Ruschoff, J., Tomasic, G., de Vijver, M. V. (2003) Current perspectives on HER2 testing: A review of national testing guidelines. MODERN PATHOLOGY, 16 (2). pp. 173-182. ISSN 0893-3952

Nerurkar, A., Osin, P. (2003) The diagnosis and management of pre-invasive breast disease - The role of new diagnostic techniques. BREAST CANCER RESEARCH, 5 (6). pp. 305-308. ISSN 1465-5411

Smith, I. E., Dowsett, M. (2003) Drug therapy: Aromatase inhibitors in breast cancer. NEW ENGLAND JOURNAL OF MEDICINE, 348 (24). pp. 2431-2442. ISSN 0028-4793

Johnston, S. R. D., Head, J., Pancholi, S., Detre, S., Martin, L. A., Smith, I. E., Dowsett, M. (2003) Integration of signal transduction inhibitors with endocrine therapy: An approach to overcoming hormone resistance in breast cancer. CLINICAL CANCER RESEARCH, 9 (1). 524S-532S. ISSN 1078-0432

Shannon C, Smith I (2003) Is there still a role for neoadjuvant therapy in breast cancer? CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 45 (1). pp. 77-90. ISSN 1040-8428

Perera NMA, Gui GPH (2003) Multi-ethnic differences in breast cancer: Current concepts and future directions. INTERNATIONAL JOURNAL OF CANCER, 106 (4). pp. 463-467. ISSN 0020-7136

Lo S, Johnston SRD (2003) Novel systemic therapies for breast cancer. SURGICAL ONCOLOGY-OXFORD, 12 (4). pp. 277-287. ISSN 0960-7404

Assersohn L, Johnston SRD (2003) Postmenopausal breast cancer; a review of first-line treatment options. AMERICAN JOURNAL OF CANCER, 2 (2). pp. 95-109. ISSN 1175-6357

Head J, Johnston SRD (2003) Protein farnesyltransferase inhibitors. EXPERT OPINION ON EMERGING DRUGS, 8 (1). pp. 163-178. ISSN 1472-8214

Sotiriou, C., Powles, T. J., Dowsett, M., Jazaeri, A. A., Feldman, A. L., Assersohn, L., Gadisetti, C., Libutti, S. K., Liu, E. T. (2002) Gene expression profiles derived from fine needle aspiration correlate with response to systemic chemotherapy in breast cancer. BREAST CANCER RESEARCH, 4 (3). ISSN 1465-5411

Marsden J (2002) Hormone-replacement therapy and breast cancer. LANCET ONCOLOGY, 3 (5). pp. 303-311. ISSN 1470-2045

Smith IE (2002) New drugs for breast cancer. LANCET, 360 (9335). pp. 790-792. ISSN 0140-6736

Smith IE, Lipton L (2001) Preoperative/ neoadjuvant medical therapy for early breast cancer. LANCET ONCOLOGY, 2 (9). pp. 561-570. ISSN 1470-2045

Parton, M., Dowsett, M., Smith, I. (2001) Studies of apoptosis in breast cancer. BRITISH MEDICAL JOURNAL, 322 (7301). pp. 1528-1538. ISSN 0007-1447

Johnston SRD (2001) Systemic treatment of metastatic breast cancer. HOSPITAL MEDICINE (LONDON, ENGLAND: 1998), 62 (5). pp. 289-295. ISSN 1462-3935