Article

Slade, I., Stephens, P., Douglas, J., Barker, K., Stebbings, L., Abbaszadeh, F., Pritchard-Jones, K., Cole, R., Pizer, B., Stiller, C., Vujanic, G., Scott, R. H., Stratton, M. R., Rahman, N., FACT Collaboration, [Group Author] (2010) Constitutional translocation breakpoint mapping by genome-wide paired-end sequencing identifies HACE1 as a putative Wilms tumour susceptibility gene. JOURNAL OF MEDICAL GENETICS, 47 (5). pp. 342-347. ISSN 0022-2593

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Williamson, D., Missiaglia, E., de Reynies, A., Pierron, G., Thuille, B., Palenzuela, G., Thway, K., Orbach, D., Lae, M., Freneaux, P., Pritchard-Jones, K., Oberlin, O., Shipley, J., Delattre, O. (2010) Fusion Gene-Negative Alveolar Rhabdomyosarcoma Is Clinically and Molecularly Indistinguishable From Embryonal Rhabdomyosarcoma. JOURNAL OF CLINICAL ONCOLOGY, 28 (13). pp. 2151-2158. ISSN 0732-183X

Skinner, R., Parry, A., Price, L., Cole, M., Craft, A. W., Pearson, A. D. J. (2010) Glomerular Toxicity Persists 10 Years After Ifosfamide Treatment in Childhood and Is Not Predictable by Age or Dose. PEDIATRIC BLOOD & CANCER, 54 (7). pp. 983-989. ISSN 1545-5009

Alrashdi, I., Levine, S., Paterson, J., Saxena, R., Patel, S. R., Depani, S., Hargrave, D. R., Pritchard-Jones, K., Hodgson, S. V. (2010) Hereditary leiomyomatosis and renal cell carcinoma: very early diagnosis of renal cancer in a paediatric patient. FAMILIAL CANCER, 9 (2). pp. 239-243. ISSN 1389-9600

Shah, A., Stiller, C., Lancaster, D., Vincent, T., Coleman, M. P. (2010) Leukaemia survival trends in children with Down's syndrome in Great Britain, 1971-2000: a population-based study. JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH, 64 (7). pp. 604-609. ISSN 0143-005X

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Veal, G. J., Cole, M., Errington, J., Pearson, A. D. J., Gerrard, M., Whyman, G., Ellershaw, C., Boddy, A. V. (2010) Pharmacokinetics of carboplatin and etoposide in infant neuroblastoma patients. CANCER CHEMOTHERAPY AND PHARMACOLOGY, 65 (6). pp. 1057-1066. ISSN 0344-5704

Ladenstein, R., Valteau-Couanet, D., Brock, P., Yaniv, I., Castel, V., Laureys, G., Malis, J., Papadakis, V., Lacerda, A., Ruud, E., Kogner, P., Garami, M., Balwierz, W., Schroeder, H., Beck-Popovic, M., Schreier, G., Machin, D., Potschger, U., Pearson, A. (2010) Randomized Trial of Prophylactic Granulocyte Colony-Stimulating Factor During Rapid COJEC Induction in Pediatric Patients With High-Risk Neuroblastoma: The European HR-NBL1/SIOPEN Study. JOURNAL OF CLINICAL ONCOLOGY, 28 (21). pp. 3516-3524. ISSN 0732-183X

Olmos, D., Postel-Vinay, S., Molife, L. R., Okuno, S. H., Schuetze, S. M., Paccagnella, M. L., Batzel, G. N., Yin, D., Pritchard-Jones, K., Judson, I., Worden, F. P., Gualberto, A., Scurr, M., de Bono, J. S., Haluska, P. (2010) Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab(CP-751,871) in patients with sarcoma and Ewing's sarcoma: a phase 1 expansion cohort study. LANCET ONCOLOGY, 11 (2). pp. 129-135. ISSN 1470-2045

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Williams, R. D., Al-Saadi, R., Chagtai, T., Popov, S., Messahel, B., Sebire, N., Gessler, M., Wegert, J., Graf, N., Leuschner, I., Hubank, M., Jones, C., Vujanic, G., Pritchard-Jones, K., Childrens Canc Leukaemia Grp, [Group Author], SIOP Wilms Tumour Biol Grp, [Group Author] (2010) Subtype-Specific FBXW7 Mutation and MYCN Copy Number Gain in Wilms' Tumor. CLINICAL CANCER RESEARCH, 16 (7). pp. 2036-2045. ISSN 1078-0432

Zacharoulis, S., Ashley, S., Moreno, L., Gentet, J., Massimino, M., Frappaz, D. (2010) Treatment and outcome of children with relapsed ependymoma: a multi-institutional retrospective analysis. CHILDS NERVOUS SYSTEM, 26 (7). pp. 905-911. ISSN 0256-7040

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Ronghe, M., Hargrave, D., Bartels, U., Tabori, U., Vaidya, S., Chandler, C., Kulkarni, A., Bouffet, E. (2010) Vincristine and Carboplatin Chemotherapy for Unresectable and/or Recurrent Low-Grade Astrocytoma of the Brainstem. PEDIATRIC BLOOD & CANCER, 55 (3). pp. 471-477. ISSN 1545-5009

Beiske, K., Burchill, S. A., Cheung, I. Y., Hiyama, E., Seeger, R. C., Cohn, S. L., Pearson, A. D. J., Matthay, K. K. (2009) Consensus criteria for sensitive detection of minimal neuroblastoma cells in bone marrow, blood and stem cell preparations by immunocytology and QRT-PCR: recommendations by the International Neuroblastoma Risk Group Task Force. BRITISH JOURNAL OF CANCER, 100 (10). pp. 1627-1637. ISSN 0007-0920

Zacharoulis, S., Moreno, L. (2009) Ependymoma: An Update. JOURNAL OF CHILD NEUROLOGY, 24 (11, Sp. Iss. SI). pp. 1431-1438. ISSN 0883-0738

De Bernardi, B., Gerrard, M., Boni, L., Rubie, H., Canete, A., Di Cataldo, A., Castel, V., de Lacerda, A. F., Ladenstein, R., Ruud, E., Brichard, B., Couturier, J., Ellershaw, C., Munzer, C., Bruzzi, P., Michon, J., Pearson, A. D. J. (2009) Excellent Outcome With Reduced Treatment for Infants With Disseminated Neuroblastoma Without MYCN Gene Amplification. JOURNAL OF CLINICAL ONCOLOGY, 27 (7). pp. 1034-1040. ISSN 0732-183X

Dallosso, A. R., Hancock, A. L., Szemes, M., Moorwood, K., Chilukamarri, L., Tsai, H., Sarkar, A., Barasch, J., Vuononvirta, R., Jones, C., Pritchard-Jones, K., Royer-Pokora, B., Lee, S. B., Owen, C., Malik, S., Feng, Y., Frank, M., Ward, A., Brown, K. W., Malik, K. (2009) Frequent Long-Range Epigenetic Silencing of Protocadherin Gene Clusters on Chromosome 5q31 in Wilms' Tumor. PLOS GENETICS, 5 (11). ISSN 1553-7390

Ambros, P.F., Ambros, I.M., Brodeur, G.M., Haber, M., Khan, J., Nakagawara, A., Schleiermacher, G., Speleman, F., Spitz, R., London, W.B., Cohn, S.L., Pearson, A.D.J., Maris, J.M. (2009) International consensus for neuroblastoma molecular diagnostics: report from the International Neuroblastoma Risk Group (INRG) Biology Committee. BRITISH JOURNAL OF CANCER, 100 (9). pp. 1471-1482. ISSN 0007-0920

Cohn, S. L., Pearson, A. D. J., London, W. B., Monclair, T., Ambros, P. F., Brodeur, G. M., Faldum, A., Hero, B., Iehara, T., Machin, D., Mosseri, V., Simon, T., Garaventa, A., Castel, V., Matthay, K. K. (2009) The International Neuroblastoma Risk Group (INRG) Classification System: An INRG Task Force Report. JOURNAL OF CLINICAL ONCOLOGY, 27 (2). pp. 289-297. ISSN 0732-183X

Monclair, T., Brodeur, G.M., Ambros, P.F., Brisse, H.J., Cecchetto, G., Holmes, K., Kaneko, M., London, W.B., Matthay, K.K., Nuchtern, J.G., von Schweinitz, D., Simon, T., Cohn, S.L., Pearson, A.D.J. (2009) The International Neuroblastoma Risk Group (INRG) Staging System: An INRG Task Force Report. JOURNAL OF CLINICAL ONCOLOGY, 27 (2). pp. 298-303. ISSN 0732-183X

Vartzelis, G., Lancaster, D., Fallon, P. (2009) Intracranial Hypertension in Pediatric Patients With Acute Lymphoblastic Leukemia. PEDIATRIC BLOOD & CANCER, 52 (3). pp. 418-420. ISSN 1545-5009

Bax, D. A., Little, S. E., Gaspar, N., Perryman, L., Marshall, L., Viana-Pereira, M., Jones, T. A., Williams, R. D., Grigoriadis, A., Vassal, G., Workman, P., Sheer, D., Reis, R. M., Pearson, A. D. J., Hargrave, D., Jones, C. (2009) Molecular and Phenotypic Characterisation of Paediatric Glioma Cell Lines as Models for Preclinical Drug Development. PLOS ONE, 4 (4). ISSN 1932-6203

Moreno, L., Bautista, F. J., Zacharoulis, S. (2009) Outcome of teenagers and young adults with ependymoma: The Royal Marsden experience. CHILDS NERVOUS SYSTEM, 25 (9). pp. 1047-1052. ISSN 0256-7040

Skinner, R., Parry, A., Price, L., Cole, M., Craft, A. W., Pearson, A. D. J. (2009) Persistent nephrotoxicity during 10-year follow-up after cisplatin or carboplatin treatment in childhood: Relevance of age and dose as risk factors. EUROPEAN JOURNAL OF CANCER, 45 (18). pp. 3213-3219. ISSN 0959-8049

Canete, A., Gerrard, M., Rubie, H., Castel, V., Di Cataldo, A., Munzer, C., Ladenstein, R., Brichard, B., Bermudez, J.D., Couturier, J., de Bernardi, B., Pearson, A.J., Michon, J. (2009) Poor Survival for Infants With MYCN-Amplified Metastatic Neuroblastoma Despite Intensified Treatment: The International Society of Paediatric Oncology European Neuroblastoma Experience. JOURNAL OF CLINICAL ONCOLOGY, 27 (7). pp. 1014-1019. ISSN 0732-183X

Messahel, B., Ashley, S., Saran, F., Ellison, D., Ironside, J., Phipps, K., Cox, T., Chong, W. K., Robinson, K., Picton, S., Pinkerton, C. R., Mallucci, C., Macarthur, D., Jaspan, T., Michalski, A., Grundy, R. G., Children's Canc Leukaemia Grp Brai, [Group Author] (2009) Relapsed intracranial ependymoma in children in the UK: Patterns of relapse, survival and therapeutic outcome. EUROPEAN JOURNAL OF CANCER, 45 (10). pp. 1815-1823. ISSN 0959-8049

Jackson, C., Dixon-Woods, M., Tobin, M., Young, B., Heney, D., Pritchard-Jones, K. (2009) Seeking consent to tissue banking: a survey of health professionals in childhood cancer. EUROPEAN JOURNAL OF CANCER CARE, 18 (4). pp. 391-400. ISSN 0961-5423

Bagatell, R., Beck-Popovic, M., London, W. B., Zhang, Y., Pearson, A. D. J., Matthay, K. K., Monclair, T., Ambros, P. F., Cohn, S. L. (2009) Significance of MYCN Amplification in International Neuroblastoma Staging System Stage 1 and 2 Neuroblastoma: A Report From the International Neuroblastoma Risk Group Database. JOURNAL OF CLINICAL ONCOLOGY, 27 (3). pp. 365-370. ISSN 0732-183X

Dommett, R., Geary, J., Freeman, S., Hartley, J., Sharland, M., Davidson, A., Tulloh, R., Taj, M., Stoneham, S., Chisholm, J. C. (2009) Successful introduction and audit of a step-down oral antibiotic strategy for low risk paediatric febrile neutropaenia in a UK, multicentre, shared care setting. EUROPEAN JOURNAL OF CANCER, 45 (16). pp. 2843-2849. ISSN 0959-8049

Ladenstein, R., Potschger, U., Hartman, O., Pearson, A. D. J., Klingebiel, T., Castel, V., Yaniv, I., Demirer, T., Dini, G., Party, EBMT Paediatric Working Party, [Group Author] (2008) 28 years of high-dose therapy and SCT for neuroblastoma in Europe: lessons from more than 4000 procedures. BONE MARROW TRANSPLANTATION, 41 (Supplement 2). S118-S127. ISSN 0268-3369

Adwan, H., Gordon, H., Nicholls, E. (2008) Are routine chest radiographs needed after fluoroscopically guided percutaneous insertion of central venous catheters in children? JOURNAL OF PEDIATRIC SURGERY, 43 (2). pp. 341-343. ISSN 0022-3468

Pritchard-Jones, K. (2008) Clinical trials for children with cancer in Europe - Still a long way from harmonisation: A report from SIOP Europe. EUROPEAN JOURNAL OF CANCER, 44 (15). pp. 2106-2111. ISSN 0959-8049

Hargrave, D., Chuang, N., Bouffet, E. (2008) Conventional MRI cannot predict survival in childhood diffuse intrinsic pontine glioma. JOURNAL OF NEURO-ONCOLOGY, 86 (3). pp. 313-319. ISSN 0167-594X

Qureshi, A., Marshall, L., Lancaster, D. (2008) Defibrotide in the prevention and treatment of veno-occlusive disease in autologous and allogeneic stem cell transplantation in children. PEDIATRIC BLOOD & CANCER, 50 (4). pp. 831-832. ISSN 1545-5009

Anoop, P., Hargrave, D., Zacharoulis, S., Saran, F. (2008) Diagnostic and therapeutic challenges owing to concurrent pontine glioma and acute lymphoblastic leukemia. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 30 (6). pp. 454-457. ISSN 1077-4114

Gerrard, M., Cairo, M. S., Weston, C., Auperin, A., Pinkerton, R., Lambilliote, A., Sposto, R., McCarthy, K., Lacombe, M. J. T., Perkins, S. L., Patte, C., FAB LMB96 Int Study Comm, [Group Author] (2008) Excellent survival following two courses of COPAD chemotherapy in children and adolescents with resected localized B-cell non-Hodgkin's lymphoma: results of the FAB/LMB 96 international study. BRITISH JOURNAL OF HAEMATOLOGY, 141 (6). pp. 840-847. ISSN 0007-1048

Pearson, A. D. J., Pinkerton, C. R., Lewis, I. J., Imeson, J., Ellershaw, C., Machin, D., European Neuroblastoma Study Grp, [Group Author], Children's Canc Leukaemia Grp, [Group Author] (2008) High-dose rapid and standard induction chemotherapy for patients aged over 1 year with stage 4 neuroblastoma: a randomised trial. LANCET ONCOLOGY, 9 (3). pp. 247-256. ISSN 1470-2045

DuBois, S. G., London, W. B., Zhang, Y., Matthay, K. K., Monclair, T., Ambros, P. F., Cohn, S. L., Pearson, A., Diller, L. (2008) Lung metastases in neuroblastoma at initial diagnosis: A report from the International Neuroblastoma Risk Group (INRG) project. PEDIATRIC BLOOD & CANCER, 51 (5). pp. 589-592. ISSN 1545-5009

Nicolin, G., Taylor, R., Baughan, C., Shannon, R., Stevens, S., Richardson, D., Kelsey, A., Pritchard-Jones, K., Mitchell, C. (2008) Outcome after pulmonary radiotherapy in Wilms' tumor patients with pulmonary metastases at diagnosis: A UK children's cancer study group, Wilms' tumour working group study. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 70 (1). pp. 175-180. ISSN 0360-3016

Ullenhagad, G. J., Spendlove, I., Watson, N. F. S., Kallmeyer, C., Pritchard-Jones, K., Durrant, L. G. (2008) T-cell responses in osteosarcoma patients vaccinated with an anti-idiotypic antibody, 105AD7, mimicking CD55. CLINICAL IMMUNOLOGY, 128 (2). pp. 148-154. ISSN 1521-6616

De Bernardi, B., Mosseri, V., Rubie, H., Castel, V., Foot, A., Ladenstein, R., Laureys, G., Beck-Popovic, M., de Lacerda, A. F., Pearson, A. D. J., De Kraker, J., Ambros, P. F., de Rycke, Y., Conte, M., Bruzzi, P., Michon, J. (2008) Treatment of localised resectable neuroblastoma. Results of the LNESG1 study by the SIOP Europe Neuroblastoma Group. BRITISH JOURNAL OF CANCER, 99 (7). pp. 1027-1033. ISSN 0007-0920

Veal, G. J., Errington, J., Tilby, M. J., Pearson, A. D. J., Foot, A. B. M., McDowell, H., Ellershaw, C., Pizer, B., Nowell, G. M., Pearson, D. G., Boddy, A. V., UKCCSG Pharmacology Working Grp, [Group Author] (2007) Adaptive dosing and platinum-DNA adduct formation in children receiving high-dose carboplatin for the treatment of solid tumours. BRITISH JOURNAL OF CANCER, 96 (5). pp. 725-731. ISSN 0007-0920

Buckley, S. E., Saran, F. H., Gaze, M. N., Chittenden, S., Partridge, M., Lancaster, D., Pearson, A., Flux, G. D. (2007) Dosimetry for fractionated I-131-mIBG therapies in patients with primary resistant high-risk neuroblastoma: Preliminary results. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS, 22 (1). pp. 105-112. ISSN 1084-9785

Scott, R. H., Homfray, T., Huxter, N. L., Mitton, S. G., Nash, R., Potter, M. N., Lancaster, D., Rahman, N. (2007) Familial T-cell non-Hodgkin lymphoma caused by biallelic MSH2 mutations. JOURNAL OF MEDICAL GENETICS, 44 (7). e83-e83. ISSN 0022-2593

Westbury, C. B., Pearson, A., Nerurkar, A., Reis-Filho, J. S., Steele, D., Peckitt, C., Sharp, G., Yarnold, J. R. (2007) Hypoxia can be detected in irradiated normal human tissue: a study using the hypoxic marker pimonidazole hydrochloride. BRITISH JOURNAL OF RADIOLOGY, 80 (959). pp. 934-938. ISSN 0007-1285

Lastowska, M., Viprey, V., Santibanez-Koref, M., Wappler, I., Peters, H., Cullinane, C., Roberts, P., Hall, A. G., Tweddle, D. A., Pearson, A. D. J., Lewis, I., Burchill, S. A., Jackson, M. S. (2007) Identification of candidate genes involved in neuroblastoma progression by combining genomic and expression microarrays with survival data. ONCOGENE, 26 (53). pp. 7432-7444. ISSN 0950-9232

Vaidya, S. J., Hargrave, D., Saran, F., Britton, J., Soomal, R., Bouffet, E. (2007) Pattern of recurrence in paediatric malignant glioma: an institutional experience. JOURNAL OF NEURO-ONCOLOGY, 83 (3). pp. 279-284. ISSN 0167-594X

Veal, G. J., Cole, M., Errington, J., Pearson, A. D. J., Foot, A. B. M., Whyman, G., Boddy, A. V., UKCCSG Working Group, [Group Author] (2007) Pharmacokinetics and metabolism of 13-cis-retinoic acid (isotretinoin) in children with high-risk neuroblastoma - a study of the United Kingdom Children's Cancer Study Group. BRITISH JOURNAL OF CANCER, 96 (3). pp. 424-431. ISSN 0007-0920

Cole, M., Price, L., Parry, A., Picton, S., Waters, F., Marshall, S., Goran, C., Parnham, A., Wastell, H., Reid, M. M., Pearson, A. D. J., Boddy, A. V., Veal, G. J. (2007) A study to determine the minimum volume of blood necessary to be discarded from a central venous catheter before a valid sample is obtained in children with cancer. PEDIATRIC BLOOD & CANCER, 48 (7). pp. 687-695. ISSN 1545-5009

Editorial

Spreafico, F., Pritchard-Jones, K., Bergeron, C., De Kraker, J., Dallorso, S., Graf, N., Int Soc Pediat Oncology Renal Tumo, [Group Author] (2009) Value and difficulties of a common European strategy for recurrent Wilms' tumor. [Editorial]

Hargrave, D. (2008) Diffuse brainstem gliomas in children: should we or shouldn't we biopsy? [Editorial]

Letter

Vartzelis, G., Lancaster, D., Fallon, P. (2009) Intracranial Hypertension in Paediatric Patients With Acute Lymphoblastic Leukaemia. [Letter]

Cutting, R., Taj, M., Vora, A. (2008) Childhood precursor B-cell acute lymphoblastic leukaemia and monosomy 7 with phenotypic shift at relapse; evidence for the stem cell origins of monosomy 7. [Letter]

Anoop, P. (2008) Decision to perform bone marrow aspiration in immune thrombocytopenic purpura must be based on evidence. [Letter]

Patel, S. R., Cohen, B., Brown, D., Heath, P. T. (2007) Reply to arya and agarwal and meisel and dilloo. [Letter]

Review Article

Moore, A. S., Blagg, J., Linardopoulos, S., Pearson, A. D. J. (2010) Aurora kinase inhibitors: novel small molecules with promising activity in acute myeloid and Philadelphia-positive leukemias. LEUKEMIA, 24 (4). pp. 671-678. ISSN 0887-6924

Zacharoulis, S., Chi, S., Kadota, R., Kieran, M. (2010) Biological Modification Strategies Following Marrow Ablative, High-Dose Chemotherapy (HDCT) With Autologous Hematopoietic Stem Cell Rescue (AHSCR) for Pediatric Brain Tumors. PEDIATRIC BLOOD & CANCER, 54 (4). pp. 654-656. ISSN 1545-5009

El-Toukhy, T., Bickerstaff, H., Meller, S. (2010) Preimplantation genetic diagnosis for haematologic conditions. CURRENT OPINION IN PEDIATRICS, 22 (1). pp. 28-34. ISSN 1040-8703

Hargrave, D. (2009) Paediatric high and low grade glioma: the impact of tumour biology on current and future therapy. BRITISH JOURNAL OF NEUROSURGERY, 23 (4). pp. 351-363. ISSN 0268-8697

Spreafico, F., Pritchard-Jones, K., Malogolowkin, M. H., Bergeron, C., Hale, J., de Kraker, J., Dallorso, S., Acha, T., de Camargo, B., Dome, J. S., Graf, N. (2009) Treatment of relapsed Wilms tumors: lessons learned. EXPERT REVIEW OF ANTICANCER THERAPY, 9 (12). pp. 1807-1815. ISSN 1473-7140